Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003499)

(Analysis AN005743)

Metabolite	Structure	F1	F2	F3
citrate	ME910222	1.47	0.52	1.01
ethanolamine phosphate	ME910242	1.66	0.14	1.21
dimethyllysine	ME910240	0.79	1.49	0.72
CMP	ME910224	1.24	0.75	1.01
ornithine	ME910311	1.14	1.00	0.86
quinolinic acid	ME910327	1.42	1.46	0.12
succinylglutathione	ME910341	0.89	1.31	0.80
IMP	ME910279	1.68	0.53	0.80
glycerylphosphorylcholine	ME910263	2.01	0.65	0.34
2-ketoglutarate	ME910190	1.92	0.68	0.40
succinate	ME910338	1.33	1.04	0.62
N-acetylaspartate	ME910295	0.83	0.98	1.20
phosphorylcholine	ME910321	1.12	0.74	1.15
FAD	ME910243	1.24	0.76	0.99
dimethylarginine	ME910239	0.95	1.23	0.82
cis-aconitate	ME910220	1.14	0.88	0.97
proline	ME910322	1.10	0.98	0.91
UDP	ME910349	1.35	0.69	0.95
UDP-hexose	ME910352	1.59	0.48	0.93
propionylcholine	ME910324	0.57	1.20	1.23
ophthalmic acid	ME910310	1.61	0.41	0.97
orotidine	ME910313	0.87	1.08	1.05
isoleucine	ME910283	1.16	1.01	0.84
N-acetylglutamate	ME910297	1.03	0.99	0.98
cyclic ADP-ribose	ME910229	0.97	1.10	0.92
ADP	ME910197	1.17	0.82	1.01
UTP	ME910356	1.46	0.67	0.87
betaine	ME910210	0.70	0.55	1.75
uric acid	ME910354	1.05	1.15	0.80
valine	ME910357	1.24	0.87	0.89
creatine	ME910226	0.78	0.69	1.52
phosphocholine	ME910317	1.12	0.74	1.15
beta-citrylglutamic acid	ME910209	0.65	1.65	0.70
leucine	ME910289	1.25	0.88	0.87
GMP	ME910266	1.13	0.72	1.15
inosine	ME910281	2.01	0.41	0.58
inositol	ME910282	0.99	1.09	0.92
uridine	ME910355	1.96	0.45	0.59
glutamine	ME910253	1.24	0.79	0.97
N-acetylornithine	ME910301	1.09	1.09	0.82
UDP-GlcNac	ME910350	1.36	0.91	0.73
glutamate	ME910252	1.40	0.58	1.02
CDP-ethanolamine	ME910217	1.64	0.31	1.05
dTTP	ME910241	1.21	0.91	0.87
creatinine	ME910227	1.21	0.89	0.90
NAD	ME910303	1.00	1.08	0.91
UDP-glucose	ME910351	1.59	0.48	0.93
CDP	ME910216	1.34	0.69	0.98
pyruvate	ME910326	1.31	1.39	0.30
carnitinamide	ME910213	1.41	0.70	0.89
glycerophosphoinositol	ME910260	0.89	1.20	0.91
adenosine	ME910195	1.03	0.65	1.32
choline	ME910219	1.27	0.73	1.00
glycerophosphoserine	ME910262	1.10	1.12	0.78
cystine	ME910233	2.09	0.58	0.33
aspartate	ME910205	1.15	0.75	1.09
citrulline	ME910223	1.08	1.17	0.75
NADPH	ME910306	1.03	0.82	1.15
cysteic acid	ME910232	1.04	0.67	1.29
nicotinamide riboside	ME910309	1.06	1.18	0.76
lysine	ME910290	1.25	0.76	1.00
taurine	ME910342	0.84	1.07	1.09
guanosine	ME910270	1.89	0.24	0.87
glutamylproline	ME910255	0.98	1.00	1.03
pantothenate	ME910315	1.66	0.61	0.74
butyrylcarnitine	ME910211	0.35	0.80	1.84
N-carbamoylglutamate	ME910308	0.98	0.81	1.21
glucuronic acid	ME910251	1.16	0.77	1.07
sedoheptulose 7-phosphate	ME910335	1.10	0.49	1.40
2-aminoadipic acid	ME910188	0.98	0.81	1.21
isovalerylcarnitine C5	ME910284	0.70	0.97	1.33
threonine	ME910344	1.47	0.62	0.91
GDP	ME910247	1.23	0.69	1.08
alanine	ME910199	0.85	1.56	0.60
homoarginine	ME910272	1.06	1.07	0.86
hydroxytrimethyllysine	ME910276	1.26	1.09	0.65
argininosuccinate	ME910203	1.02	1.30	0.69
N-acetylaspartylglutamate	ME910296	0.44	1.61	0.96
kynurenine	ME910287	0.59	1.00	1.42
methionine sulfoxide	ME910293	1.16	1.03	0.81
UMP	ME910353	1.25	0.74	1.00
glycerophosphorylcholine	ME910261	2.01	0.65	0.34
hypotaurine	ME910277	0.84	1.11	1.04
fructose 1,6-bisphosphate	ME910244	1.29	0.73	0.98
phosphoenolpyruvate	ME910319	1.22	0.92	0.85
citicoline	ME910221	1.64	0.69	0.67
N-carbamoylaspartate	ME910307	0.52	1.72	0.76
N-acetylhistidine	ME910299	1.11	1.19	0.70
glutamylcysteine	ME910254	1.17	0.96	0.88
xanthine	ME910359	1.14	0.99	0.88
N-acetylneuramic acid	ME910300	1.26	0.84	0.90
malate	ME910291	1.03	1.30	0.67
fructose 6-Phosphate	ME910245	1.39	0.92	0.69
S-(2-Succinyl)glutathione	ME910329	0.89	1.31	0.80
orotate	ME910312	2.34	0.34	0.33
N-acetylhexosamine phosphate	ME910298	1.51	0.70	0.80
succinyladenosine	ME910339	NA	0.13	1.87
oxidized glutathione	ME910314	1.23	0.72	1.04
tryptophan	ME910347	1.34	0.68	0.98
glycylglycine	ME910265	0.91	0.84	1.25
serine	ME910336	1.82	0.31	0.88
cystathionine	ME910231	1.59	0.78	0.63
carnitine	ME910214	0.46	1.16	1.38
aspartylglucosamine	ME910206	0.90	0.97	1.13
carnosine	ME910215	1.37	0.79	0.84
sarcosine	ME910334	1.06	1.05	0.89
fumarate	ME910246	1.02	1.32	0.66
AMP	ME910201	1.25	0.81	0.94
CTP	ME910228	1.46	0.61	0.93
glycerol 3-phosphate	ME910258	1.82	0.59	0.59
hypoxanthine	ME910278	2.10	0.40	0.50
ADP-ribose	ME910198	0.89	0.88	1.24
2/3-phosphoglycerate	ME910187	1.41	0.66	0.93
dihydroorotate	ME910237	0.78	1.08	1.14
2-hydroxyglutarate	ME910189	1.29	0.96	0.76
acetylcarnitine	ME910192	0.50	1.11	1.38
asparagine	ME910204	1.24	0.91	0.85
Cys-Gly	ME910230	0.95	0.91	1.15
4-guanidinobutanoate	ME910191	0.65	1.42	0.93
phosphocreatine	ME910318	1.74	0.64	0.63
cytidine	ME910234	1.93	0.57	0.50
ATP	ME910207	1.33	0.74	0.93
arginine	ME910202	1.07	1.03	0.91
beta-alanine	ME910208	0.63	1.64	0.73
phenylalanine	ME910316	1.28	0.81	0.91
glutathione	ME910256	0.96	0.90	1.14
guanine	ME910269	1.95	0.19	0.86
N-acetylarginine	ME910294	1.06	1.17	0.78
gluconate	ME910249	1.16	1.26	0.58
glyceraldehyde 3-phosphate	ME910257	1.21	0.95	0.84
cAMP	ME910212	1.02	1.28	0.70
propionylcarnitine	ME910323	0.69	1.20	1.12
deoxycytidine	ME910235	0.73	1.49	0.78
methionine	ME910292	1.40	0.68	0.92
S-adenosylhomocysteine	ME910331	0.87	0.95	1.18
S-adenosylmethionine	ME910332	1.24	0.84	0.92
acetyl-CoA	ME910194	0.97	1.26	0.77
lactate	ME910288	0.93	1.46	0.62
glycine	ME910264	2.32	0.30	0.39
GTP	ME910267	1.29	0.67	1.04
histidine	ME910271	1.15	1.06	0.80
GDP-glucose	ME910248	1.04	1.12	0.84
NADH	ME910304	0.64	0.76	1.60
trimethyllysine	ME910345	0.81	1.32	0.86
dihydroxyacetone phosphate	ME910238	1.36	0.84	0.80
succinylcarnitine	ME910340	0.54	1.37	1.09
hydroxyproline	ME910275	1.25	1.12	0.63
NADP	ME910305	1.13	0.79	1.08
thiamine	ME910343	0.55	1.61	0.84
adenylosuccinate	ME910196	0.17	0.22	2.61
S-(2-succinyl)cysteine	ME910328	1.24	1.18	0.58
hydroxyphenyllactate	ME910274	1.69	0.55	0.77
glucose 6-phosphate	ME910250	1.39	1.03	0.58
guanidineacetic acid	ME910268	0.47	0.61	1.92
glycerophosphoethanolamine	ME910259	1.93	0.66	0.42
tyrosine	ME910348	1.17	0.98	0.85
phosphoethanolamine	ME910320	1.67	0.13	1.20
hydantoin-5-propionic acid	ME910273	1.15	0.80	1.06
pyroglutamic acid	ME910325	1.06	1.08	0.85
CMP-acetylneuraminic acid	ME910225	1.25	0.81	0.94
aminobutyrate	ME910200	1.39	0.58	1.03
acetylcholine	ME910193	0.80	0.83	1.37
S-lactoylglutathione	ME910337	0.78	1.53	0.69
N-acetylserine	ME910302	0.81	1.04	1.14
deoxyribose 5-phosphate	ME910236	0.99	0.83	1.18
valine-d8	ME910358	0.99	1.02	0.99

Factors:

F1	Phenotype:Control \| Genotype:Wildtype
F2	Phenotype:Mild \| Genotype:R309H/c.1191+5G->C
F3	Phenotype:Mild \| Genotype:T450S/D332H

Data matrix