Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003606)

(Analysis AN005925)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15	F16	F17	F18	F19	F20
5-Aminopentanoate	ME934974	0.50	0.81	0.34	0.27	0.60	0.54	0.34	0.26	0.92	0.61	0.33	0.31	0.51	0.52	14.71	0.30	0.46	0.79	0.41	0.30
Dehydroascorbate	ME934964	0.79	0.60	0.13	0.30	0.61	0.50	0.34	0.42	0.93	0.83	0.31	0.47	0.57	0.46	9.83	0.37	0.40	0.58	0.77	1.53
Octadecatrienoic acid (linolenic acid)	ME934994	0.34	0.51	0.26	0.33	0.32	0.31	0.94	0.29	0.52	0.46	0.28	0.29	0.33	0.30	4.75	0.31	0.37	12.12	0.31	0.32
Linoleate	ME934993	0.76	1.01	0.51	0.50	0.70	0.67	1.26	0.40	1.08	0.81	0.37	0.48	0.58	0.60	3.69	0.47	0.77	7.15	0.60	0.47
Hexadecenoic acid	ME934991	0.54	0.83	0.41	0.40	0.54	0.53	5.52	0.35	0.65	0.56	0.30	0.35	0.46	0.53	1.11	0.40	0.58	8.31	0.45	0.42
Tetradecenoic acid	ME934990	0.51	0.71	0.42	0.49	0.52	0.44	4.38	0.41	0.50	0.48	0.45	0.43	0.47	0.53	1.28	0.43	0.49	8.92	0.49	0.52
4-Pyridoxate	ME934937	0.69	0.62	0.29	0.32	0.54	0.51	0.74	0.34	0.57	0.23	0.16	0.19	0.24	0.27	5.67	0.29	0.52	0.66	4.36	3.32
Inosine	ME934934	0.97	1.22	0.27	0.36	1.12	1.06	0.15	0.32	5.35	4.03	1.49	1.14	0.71	1.01	0.63	0.66	0.77	0.82	0.40	0.45
Hypoxanthine	ME934935	1.00	1.22	0.30	0.45	1.20	1.00	0.26	0.31	3.02	2.58	1.01	0.96	0.88	0.98	4.46	0.53	0.80	0.97	0.51	0.50
2-Oxoglutaramate	ME934951	0.40	1.29	0.98	1.58	0.97	0.46	1.28	0.86	0.79	0.69	1.23	0.09	0.23	0.60	4.67	0.98	0.90	1.12	0.99	0.65
Lactate	ME934945	1.40	1.74	0.64	0.99	1.53	1.28	0.58	0.76	0.76	0.53	0.29	0.73	1.02	0.62	4.68	0.73	0.79	0.91	0.43	0.69
Mannitol	ME934947	1.24	1.31	0.82	1.04	1.71	1.13	0.56	1.06	0.28	0.61	0.15	0.30	0.70	0.58	5.97	1.19	0.51	0.59	0.25	0.40
Maltose	ME934946	0.38	0.88	0.79	0.66	0.62	0.88	1.97	0.68	0.56	0.29	0.80	0.94	0.16	0.52	0.88	0.44	0.65	3.55	3.48	1.45
Octadecenoic acid (oleic acid)	ME934992	0.82	1.21	0.67	0.59	0.82	0.93	1.50	0.54	1.13	1.06	0.54	0.62	0.78	0.82	2.45	0.69	1.02	4.14	1.02	0.68
Tetradecanoic acid	ME934987	0.86	1.04	0.88	0.84	0.86	0.88	1.69	0.85	0.83	0.89	0.86	0.78	0.80	0.90	1.16	0.83	1.02	3.25	0.90	0.78
2/3-Phospho-D-glycerate	ME934943	0.96	1.53	0.35	0.56	1.43	1.22	0.58	0.74	0.56	0.34	0.04	0.26	2.08	1.27	0.36	0.43	1.45	1.30	2.44	2.07
Citrate	ME934949	1.21	0.67	0.40	0.51	1.20	0.62	0.48	0.60	0.83	1.49	0.37	0.98	2.11	0.96	0.81	0.55	1.19	0.69	2.56	2.10
fumarate 13C4	ME934925	NA	0.06	NA	0.84	0.26	0.60	0.07	1.37	NA	NA	NA	NA	1.25	0.69	0.52	1.56	0.71	0.71	0.49	1.24
malate 13C4	ME934926	0.34	0.35	0.21	0.75	0.41	0.39	0.24	1.64	NA	NA	0.02	NA	1.58	1.11	0.94	1.51	1.19	0.92	0.51	1.88
dAMP	ME934928	0.77	0.97	0.35	0.53	0.61	0.72	0.22	0.73	NA	NA	NA	NA	2.38	1.95	1.72	0.99	0.91	0.93	0.91	1.12
D-Arabitol	ME934948	0.80	0.89	0.58	0.98	0.97	0.72	0.28	0.50	0.08	0.10	0.05	0.13	1.66	1.55	1.44	1.86	1.79	2.04	1.04	1.46
itaconate 13C5	ME934924	0.59	0.80	0.45	0.42	0.63	0.90	0.42	0.43	0.34	0.27	0.24	0.26	1.49	1.87	1.53	2.39	1.52	2.23	1.18	1.31
2-Oxoglutarate	ME934950	1.08	1.30	1.43	1.27	0.91	1.12	0.91	0.80	0.09	0.13	2.70	2.66	0.88	0.51	1.37	1.30	0.31	0.24	0.51	0.57
Ascorbate	ME934963	1.10	1.15	1.09	1.51	0.84	0.96	0.50	0.67	0.08	0.06	1.39	1.73	1.37	1.17	1.80	1.89	0.49	0.39	0.38	0.57
Pyruvate	ME934944	0.85	1.17	0.79	1.20	0.79	0.90	0.79	0.73	0.61	1.43	1.05	1.41	1.03	0.91	2.56	1.41	0.47	0.57	0.55	0.71
Argininosuccinate	ME934967	2.66	2.41	0.43	1.34	2.31	1.32	0.97	1.73	0.33	0.27	0.15	0.27	0.97	0.37	0.68	0.49	0.59	0.28	0.97	0.75
Sedoheptulose 1-phosphate	ME934958	2.61	3.23	0.91	1.34	2.45	2.20	0.64	1.03	0.93	0.60	0.34	0.48	0.50	0.47	0.21	0.30	0.42	0.38	0.85	0.81
Cytidine	ME934931	2.18	2.80	0.88	1.30	2.23	2.35	0.74	0.70	0.91	1.18	0.29	0.41	0.80	0.86	0.67	0.57	0.96	0.95	0.25	0.37
sn-glycero-3-Phosphoethanolamine	ME934981	2.01	2.74	0.88	1.24	2.10	2.21	0.75	0.90	0.78	1.08	0.32	0.47	0.92	0.83	0.47	0.73	0.88	0.81	0.31	0.46
1-4-beta-D-Xylan	ME934971	1.24	1.73	0.92	0.96	0.94	1.07	0.47	0.48	1.26	3.48	1.70	2.73	0.83	0.68	0.80	0.75	0.54	0.50	0.39	0.40
Glutathione disulfide	ME934961	1.74	2.15	0.65	0.83	1.78	0.84	0.50	0.45	2.22	2.24	1.38	0.67	0.25	1.33	0.21	0.71	0.80	0.41	0.53	0.51
Hypotaurine	ME934976	2.14	1.98	0.69	0.87	1.99	1.49	0.52	0.44	2.30	3.09	1.14	1.64	0.93	0.61	0.48	0.64	0.69	0.42	0.19	0.22
Taurine	ME934975	1.81	1.96	0.70	1.00	1.66	1.38	0.47	0.52	2.47	2.67	1.35	1.72	0.78	0.68	0.49	0.71	0.69	0.53	0.15	0.27
Ethanolamine phosphate	ME934980	1.77	2.33	0.75	0.86	1.59	1.55	0.51	0.66	1.77	2.52	0.77	1.22	1.29	0.92	0.66	0.73	0.83	0.63	0.24	0.32
Itaconate	ME934956	1.89	2.55	1.05	1.03	1.68	1.70	0.65	0.66	1.18	2.16	0.67	0.97	1.30	0.95	0.59	0.58	1.01	0.74	0.25	0.30
IMP	ME934933	1.22	1.61	0.39	0.69	1.96	1.01	0.19	0.26	3.12	2.76	1.29	1.79	0.68	0.58	1.21	0.77	0.71	0.61	0.57	0.69
AMP	ME934927	1.63	1.98	0.43	0.54	1.73	1.52	0.36	0.28	1.87	3.29	0.88	1.92	1.28	1.01	0.48	0.52	1.46	1.16	0.39	0.35
GMP	ME934929	1.00	1.99	0.37	0.53	1.09	1.44	0.32	0.39	2.61	3.24	0.91	1.10	0.93	0.98	0.51	0.69	1.23	0.92	0.91	0.86
UMP	ME934932	1.53	1.81	0.35	0.46	1.13	1.35	0.24	0.29	2.61	3.35	1.07	1.31	1.39	1.23	0.55	0.60	1.35	1.00	0.48	0.61
Succinate	ME934952	1.05	1.31	0.62	0.41	0.90	0.93	1.16	0.60	1.24	2.61	0.84	0.64	1.11	0.98	0.97	0.49	0.99	1.62	2.09	1.20
(8Z-11Z-14Z)-Icosatrienoic acid	ME934998	0.92	1.08	0.67	0.72	0.96	0.90	0.90	0.75	2.04	1.42	0.89	1.05	0.68	0.78	1.13	0.99	0.99	1.39	1.31	1.07
Eicosatetraenoic acid	ME934995	0.97	1.03	0.60	0.76	0.91	0.97	0.89	0.81	2.11	1.47	0.99	1.05	0.64	0.69	0.84	0.89	0.93	1.09	1.36	1.32
(5Z-8Z-11Z-14Z-17Z)-Icosapentaenoic acid	ME934999	1.02	1.29	0.57	0.70	0.95	1.14	0.66	0.72	2.91	2.11	0.97	1.33	0.54	0.46	0.89	0.75	0.62	0.90	1.18	1.17
Eicosapentaenoic acid	ME934996	1.02	1.29	0.57	0.70	0.95	1.14	0.66	0.72	2.91	2.11	0.97	1.33	0.54	0.46	0.89	0.75	0.62	0.90	1.18	1.17
(7Z-10Z-13Z-16Z-19Z)-Docosa-7-10-13-16-19-pentaenoic acid	ME935000	1.23	1.46	0.61	0.61	1.06	1.07	0.72	0.60	3.03	2.22	0.80	1.02	0.71	0.80	0.88	0.70	0.98	1.10	1.00	0.94
Docosahexaenoic acid	ME934997	1.43	1.61	0.54	0.59	1.28	1.23	0.66	0.58	2.93	2.23	0.74	0.87	0.89	0.90	0.80	0.64	1.07	1.15	0.92	0.80
N-Acetylneuraminate	ME934968	1.24	1.75	0.86	0.45	0.79	0.89	0.39	0.28	1.61	1.75	0.93	1.05	1.76	1.78	1.58	1.13	1.20	1.23	0.79	0.59
N-Glycoloyl-neuraminate	ME934969	1.29	1.42	1.06	0.57	0.95	0.83	0.39	0.37	1.72	1.53	1.14	1.11	1.74	1.35	1.53	1.19	1.29	0.95	0.74	0.57
UDP-N-acetyl-D-glucosamine	ME934972	1.14	1.20	0.52	0.44	0.96	0.81	0.55	0.43	1.86	2.17	0.96	1.45	1.76	1.02	0.79	0.60	1.58	1.09	1.49	1.08
ADP-D-ribose	ME934939	1.16	1.96	0.57	0.23	1.58	1.74	0.77	0.48	1.76	1.86	1.35	1.22	1.21	1.25	0.60	0.51	1.18	1.36	1.07	0.73
alpha-D-Ribose 1-phosphate	ME934959	1.55	1.59	0.51	0.67	1.57	1.40	0.40	0.55	2.35	2.22	0.86	0.86	1.22	1.28	0.49	0.58	1.25	1.08	0.68	0.79
CMP	ME934930	1.29	1.75	0.53	0.43	1.03	1.31	0.48	0.40	1.76	2.05	0.78	1.09	1.27	1.12	0.86	0.82	1.31	1.14	1.09	1.13
Glutathione	ME934960	1.61	1.89	0.59	0.76	1.22	1.30	0.50	0.58	1.57	2.47	0.55	1.26	1.39	1.01	0.51	0.74	1.01	0.74	0.89	0.84
UDP-glucose	ME934938	1.17	1.14	0.48	0.53	1.33	0.92	0.54	0.36	1.48	1.43	0.71	1.10	2.32	1.56	0.73	0.69	2.32	1.36	1.06	0.87
Fumarate	ME934953	1.15	1.35	0.48	1.17	0.99	0.97	1.03	1.54	1.01	1.22	0.31	0.68	1.29	0.94	1.33	0.76	0.84	0.67	0.73	0.96
Malate	ME934954	1.22	1.35	0.48	1.27	1.16	1.01	1.09	1.60	0.93	1.05	0.27	0.64	1.42	0.99	0.65	0.78	0.84	0.69	0.66	1.02
Dimethylglycine	ME934965	0.95	1.14	0.75	1.13	1.61	0.97	0.55	0.66	0.75	0.90	0.64	0.78	0.94	1.04	0.96	1.49	1.58	1.57	0.79	0.76
Octadecanoic acid (stearic acid)	ME934989	1.06	0.95	0.88	0.85	0.99	1.02	0.89	1.10	0.94	1.01	0.85	0.76	0.93	0.84	1.35	0.98	0.93	1.09	0.97	1.31
Hexanoic acid (caproate)	ME934982	0.84	1.10	0.98	1.16	0.99	1.06	1.12	0.87	1.05	1.02	1.16	1.11	0.74	0.96	1.02	0.99	0.89	1.33	0.91	0.86
Octanoic acid (caprylate)	ME934984	0.86	1.06	1.05	1.18	1.00	1.01	1.01	0.91	1.00	1.01	1.06	1.08	0.84	0.87	1.09	0.98	0.91	1.30	1.07	0.84
Heptanoic acid	ME934983	0.82	1.10	1.07	1.14	1.02	1.06	1.04	0.92	1.12	1.02	1.02	1.01	0.78	0.94	1.08	0.96	0.96	1.13	1.00	0.91
Nonanoic acid (pelargonate)	ME934985	0.85	1.07	1.10	1.15	0.97	0.98	1.01	0.96	1.11	1.03	1.01	1.01	0.78	0.99	1.05	0.98	1.06	1.17	1.07	0.79
Dodecanoic acid	ME934986	0.92	1.02	1.05	0.98	0.96	0.85	1.27	0.89	0.92	0.92	0.93	0.96	0.85	0.99	1.22	0.97	0.95	1.88	0.97	0.87
Hexadecanoic acid	ME934988	0.97	1.11	0.96	1.03	0.99	0.95	1.25	0.86	0.99	1.04	0.99	0.88	0.81	0.93	1.50	0.86	1.04	1.51	1.00	0.86
D-Glucose	ME934942	0.86	1.24	0.89	0.92	1.27	1.06	0.86	0.89	0.74	0.85	0.65	1.19	1.38	1.10	1.03	1.03	1.06	1.34	1.07	0.91
D-Glucono-1-5-lactone 6-phosphate	ME934957	1.03	0.83	0.80	0.69	0.89	1.03	0.87	1.18	0.81	0.89	0.61	1.03	1.71	1.19	1.23	0.98	1.15	0.76	1.05	1.20
Diphosphate	ME934941	0.79	0.98	0.58	0.84	1.08	0.77	0.66	1.16	0.88	1.12	0.43	0.60	1.72	1.26	1.02	1.11	1.29	1.06	1.09	1.17
Phosphate	ME934940	0.88	0.97	0.79	0.95	1.03	0.89	0.88	1.10	0.96	1.01	0.68	0.77	1.32	1.10	1.01	1.07	1.07	1.04	1.08	1.10
2-Hydroxyglutarate/Citramalate	ME934955	1.38	2.33	1.02	1.22	1.42	1.76	0.52	0.51	0.59	1.01	1.96	2.22	0.88	0.82	0.77	0.84	0.59	0.71	0.37	0.42
alpha-D-Glucosamine 1-phosphate	ME934970	1.55	2.82	1.05	0.94	1.79	1.88	0.71	0.64	1.28	1.44	0.46	0.71	0.77	0.54	0.91	0.36	0.82	0.78	1.57	0.75
S-Glutathionyl-L-cysteine	ME934962	1.51	2.99	0.89	1.15	1.75	1.16	0.59	0.58	1.27	1.85	0.81	1.11	0.56	0.54	0.37	0.68	1.09	0.94	0.79	0.63
Glycerol 3-phosphate	ME934979	1.89	1.99	0.93	1.01	1.96	1.51	0.63	0.72	0.77	0.57	0.42	0.76	1.51	0.84	1.17	0.80	1.01	0.88	0.81	0.75
L-Cysteate	ME934978	1.39	2.43	1.33	1.33	1.61	1.10	0.68	0.65	1.01	0.93	1.23	0.77	0.31	0.76	0.56	0.74	1.47	1.41	0.66	0.45
3-Phosphonooxypyruvate	ME934966	1.24	1.76	1.11	1.00	1.31	1.21	0.89	0.76	0.96	1.16	1.05	1.00	0.80	1.04	0.81	0.95	1.10	1.08	0.94	0.66
3-Sulfino-L-alanine	ME934977	1.22	2.10	1.17	1.24	1.56	1.38	0.71	0.62	1.05	1.06	0.97	1.10	0.72	0.81	0.75	0.77	1.49	1.25	0.78	0.46
5-6-Dihydrothymine	ME934936	1.71	1.90	1.12	1.15	1.49	1.38	0.79	0.59	1.34	1.40	1.28	1.81	0.93	0.77	0.97	0.64	0.66	0.61	0.63	0.43
trans-4-Hydroxy-L-proline	ME934973	1.44	1.82	0.86	1.20	1.45	1.21	0.63	0.61	1.04	1.23	1.55	1.07	0.83	0.84	1.75	0.84	0.88	0.85	0.50	0.51

Factors:

F1	time (h):18 \| E coli treatment:dead \| genotype:Cre
F2	time (h):18 \| E coli treatment:dead \| genotype:Cre KRAS +/+
F3	time (h):18 \| E coli treatment:dead \| genotype:HRAS +/+
F4	time (h):18 \| E coli treatment:dead \| genotype:WT
F5	time (h):18 \| E coli treatment:live \| genotype:Cre
F6	time (h):18 \| E coli treatment:live \| genotype:Cre KRAS +/+
F7	time (h):18 \| E coli treatment:live \| genotype:HRAS +/+
F8	time (h):18 \| E coli treatment:live \| genotype:WT
F9	time (h):18 \| E coli treatment:none \| genotype:Cre
F10	time (h):18 \| E coli treatment:none \| genotype:Cre KRAS +/+
F11	time (h):18 \| E coli treatment:none \| genotype:HRAS +/+
F12	time (h):18 \| E coli treatment:none \| genotype:WT
F13	time (h):6 \| E coli treatment:dead \| genotype:Cre
F14	time (h):6 \| E coli treatment:dead \| genotype:Cre KRAS +/+
F15	time (h):6 \| E coli treatment:dead \| genotype:HRAS +/+
F16	time (h):6 \| E coli treatment:dead \| genotype:WT
F17	time (h):6 \| E coli treatment:live \| genotype:Cre
F18	time (h):6 \| E coli treatment:live \| genotype:Cre KRAS +/+
F19	time (h):6 \| E coli treatment:live \| genotype:HRAS +/+
F20	time (h):6 \| E coli treatment:live \| genotype:WT

Data matrix