Clustering data with hclust algorithm for (Study ST003883)
(Analysis AN006377)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3-Phenylbutyric acid | ME1025534 | 1.04 | 1.25 | 1.19 | 1.15 | 1.16 | NA | NA | NA | NA | NA | NA | NA | NA | 0.90 | 0.81 | 0.85 | 0.91 |
| 2 4-Diamino-6-hydroxypyrimidine | ME1025530 | 0.93 | 0.62 | 0.64 | 0.89 | 1.24 | NA | NA | NA | NA | NA | NA | NA | NA | 0.95 | 1.24 | 0.78 | 1.14 |
| cADP-Ribose | ME1025637 | 0.69 | 0.70 | 0.70 | 0.52 | 0.41 | NA | NA | NA | NA | NA | NA | NA | NA | 1.56 | 0.92 | 1.68 | 1.40 |
| AMP | ME1025543 | 1.08 | 0.58 | 0.94 | 1.15 | 1.37 | NA | NA | NA | NA | NA | NA | NA | NA | 0.85 | 1.00 | 0.80 | 0.92 |
| Arginine | ME1025552 | 0.88 | 0.95 | 1.13 | 0.87 | 1.08 | NA | NA | NA | NA | NA | NA | NA | NA | 0.96 | 0.81 | 1.05 | 1.13 |
| ATP | ME1025544 | 1.57 | 1.30 | 1.34 | 0.92 | 0.61 | NA | NA | NA | NA | NA | NA | NA | NA | 1.20 | 0.46 | 1.00 | 0.89 |
| 4-Aminobutyrate | ME1025535 | 1.45 | 1.45 | 1.00 | 1.94 | 1.18 | NA | NA | NA | NA | NA | NA | NA | NA | 0.68 | 0.96 | 0.56 | 0.70 |
| Biotin | ME1025556 | 0.47 | 0.57 | 0.88 | 0.74 | 0.86 | NA | NA | NA | NA | NA | NA | NA | NA | 1.41 | 0.98 | 1.30 | 1.20 |
| 3-Methylindole | ME1025533 | 0.54 | 0.19 | 0.41 | 0.37 | 1.14 | NA | NA | NA | NA | NA | NA | NA | NA | 0.29 | 4.17 | 0.21 | 0.29 |
| 5- Methylthioadenosine | ME1025538 | 1.06 | 1.08 | 0.92 | 0.78 | 0.77 | NA | NA | NA | NA | NA | NA | NA | NA | 0.95 | 0.78 | 1.30 | 1.49 |
| Adenine | ME1025548 | 0.39 | 0.46 | 0.62 | 0.44 | 0.51 | NA | NA | NA | NA | NA | NA | NA | NA | 1.30 | 1.44 | 1.76 | 1.35 |
| 5-Methoxytryptophan | ME1025540 | 1.44 | 0.09 | 1.36 | 0.79 | 2.17 | NA | NA | NA | NA | NA | NA | NA | NA | 0.36 | 0.76 | 0.28 | 0.75 |
| ADP | ME1025542 | 1.14 | 0.83 | 0.85 | 1.09 | 0.89 | NA | NA | NA | NA | NA | NA | NA | NA | 1.35 | 0.66 | 1.18 | 0.98 |
| 5-Aminoimidazole-4-carboxamide ribonucleotide | ME1025539 | 0.61 | 0.38 | 0.96 | 0.53 | 0.71 | NA | NA | NA | NA | NA | NA | NA | NA | 1.60 | 0.69 | 1.28 | 1.19 |
| Adenosine | ME1025549 | 0.41 | 0.26 | 0.54 | 0.27 | 0.43 | NA | NA | NA | NA | NA | NA | NA | NA | 1.87 | 0.87 | 2.18 | 1.18 |
| Acetyl-arginine | ME1025545 | 1.00 | 1.18 | 1.30 | 1.05 | 1.35 | NA | NA | NA | NA | NA | NA | NA | NA | 0.81 | 0.74 | 0.81 | 0.87 |
| 4-Guanidinobutanoic acid | ME1025536 | 0.87 | 0.79 | 1.08 | 1.21 | 1.09 | NA | NA | NA | NA | NA | NA | NA | NA | 0.88 | 1.37 | 0.70 | 0.80 |
| 2-Ketoisovalerate | ME1025531 | 1.11 | 0.82 | 1.07 | 1.16 | 1.02 | NA | NA | NA | NA | NA | NA | NA | NA | 0.89 | 1.06 | 0.80 | 0.97 |
| Betaine | ME1025555 | 0.96 | 0.64 | 0.89 | 1.04 | 1.04 | NA | NA | NA | NA | NA | NA | NA | NA | 1.06 | 0.78 | 1.20 | 1.13 |
| 4-Methylcatechol | ME1025537 | 2.04 | 0.23 | 1.42 | 1.23 | 1.67 | NA | NA | NA | NA | NA | NA | NA | NA | 0.34 | 0.76 | 0.31 | 0.37 |
| Acetylcholine | ME1025546 | 1.69 | 0.22 | 1.03 | 0.51 | 0.29 | NA | NA | NA | NA | NA | NA | NA | NA | 1.75 | 0.32 | 1.82 | 0.46 |
| 1-Methylimidazole acetic acid | ME1025528 | 1.01 | 0.74 | 0.90 | 0.97 | 1.13 | NA | NA | NA | NA | NA | NA | NA | NA | 1.14 | 1.02 | 0.82 | 1.04 |
| Aminoadipic acid | ME1025550 | 0.43 | 1.10 | 1.53 | 0.61 | 1.88 | NA | NA | NA | NA | NA | NA | NA | NA | 0.99 | 0.45 | 0.85 | 0.76 |
| Carnitine | ME1025559 | 1.02 | 0.89 | 1.11 | 1.03 | 1.27 | NA | NA | NA | NA | NA | NA | NA | NA | 0.82 | 0.82 | 0.96 | 0.99 |
| Anserine | ME1025551 | 0.50 | 0.66 | 0.83 | 0.90 | 1.00 | NA | NA | NA | NA | NA | NA | NA | NA | 0.93 | 1.02 | 1.75 | 1.01 |
| Asparagine | ME1025553 | 0.64 | 0.51 | 0.64 | 0.68 | 0.66 | NA | NA | NA | NA | NA | NA | NA | NA | 1.42 | 1.05 | 1.55 | 1.32 |
| 2 3-Bisphosphoglycerate | ME1025529 | 0.97 | 0.37 | 1.12 | 0.97 | 2.04 | NA | NA | NA | NA | NA | NA | NA | NA | 1.00 | 0.81 | 0.54 | 0.40 |
| 1-Methylhistidine | ME1025527 | 0.72 | 1.10 | 0.98 | 0.95 | 1.00 | NA | NA | NA | NA | NA | NA | NA | NA | 1.08 | 0.75 | 1.50 | 0.95 |
| 3-Hydroxyanthranilic acid | ME1025532 | 0.67 | 1.13 | 1.04 | 0.90 | 0.97 | NA | NA | NA | NA | NA | NA | NA | NA | 1.56 | 0.90 | 0.98 | 0.74 |
| Acetyllysine | ME1025547 | 0.80 | 0.76 | 0.90 | 0.87 | 1.32 | NA | NA | NA | NA | NA | NA | NA | NA | 0.83 | 1.43 | 0.86 | 0.87 |
| Aspartate | ME1025554 | 0.37 | 1.32 | 1.69 | 0.90 | 1.66 | NA | NA | NA | NA | NA | NA | NA | NA | 0.90 | 0.32 | 0.86 | 0.92 |
Factors:
| F1 | Sample source:Lung | Age:Old | Genotype:PolG |
| F2 | Sample source:Lung | Age:Old | Genotype:Wt |
| F3 | Sample source:Lung | Age:Old | Genotype:WT |
| F4 | Sample source:Lung | Age:Young | Genotype:PolG |
| F5 | Sample source:Lung | Age:Young | Genotype:WT |
| F6 | Sample source:Plasma | Age:Old | Genotype:KP |
| F7 | Sample source:Plasma | Age:Old | Genotype:PGKP |
| F8 | Sample source:Plasma | Age:Old | Genotype:PolG |
| F9 | Sample source:Plasma | Age:Old | Genotype:WT |
| F10 | Sample source:Plasma | Age:Young | Genotype:KP |
| F11 | Sample source:Plasma | Age:Young | Genotype:PGKP |
| F12 | Sample source:Plasma | Age:Young | Genotype:PolG |
| F13 | Sample source:Plasma | Age:Young | Genotype:WT |
| F14 | Sample source:Tumor | Age:Old | Genotype:KP |
| F15 | Sample source:Tumor | Age:Old | Genotype:PGKP |
| F16 | Sample source:Tumor | Age:Young | Genotype:KP |
| F17 | Sample source:Tumor | Age:Young | Genotype:PGKP |
