Clustering data with hclust algorithm for (Study ST004339)
(Analysis AN007246)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DTDP-D-GLUCOSE | ME1194835 | 1.15 | 1.29 | 1.14 | 1.29 | 0.79 | 0.75 | 0.84 | 0.89 | 0.90 | 0.96 | NA | NA | NA | NA | NA | NA |
| PURINE | ME1194855 | 0.88 | 1.00 | 1.00 | 0.89 | 0.71 | 1.22 | 1.13 | 1.00 | 1.04 | 1.13 | NA | NA | NA | NA | NA | NA |
| CREATININE | ME1194828 | 1.28 | 0.86 | 1.06 | 0.92 | 1.03 | 0.97 | 0.90 | 0.84 | 0.99 | 1.16 | NA | NA | NA | NA | NA | NA |
| DEOXYCYTIDINE-DIPHOSPHATE | ME1194832 | 0.93 | 0.91 | 0.97 | 0.94 | 0.81 | 0.96 | 1.10 | 1.13 | 1.13 | 1.12 | NA | NA | NA | NA | NA | NA |
| BETA-GLYCEROPHOSPHATE | ME1194824 | 0.89 | 0.90 | 0.66 | 1.10 | 0.87 | 0.82 | 0.90 | 1.33 | 1.16 | 1.36 | NA | NA | NA | NA | NA | NA |
| CDP-ETHANOLAMINE | ME1194826 | 1.08 | 1.15 | 1.47 | 0.94 | 0.54 | 1.00 | 1.14 | 0.84 | 0.91 | 0.94 | NA | NA | NA | NA | NA | NA |
| ANILINE-2-SULFONATE | ME1194820 | NA | 0.68 | 1.17 | 1.20 | 3.94 | 0.65 | 0.77 | NA | 1.55 | 0.71 | NA | NA | NA | NA | NA | NA |
| THYMIDINE-MONOPHOSPHATE | ME1194861 | 0.96 | 0.96 | 0.78 | 0.93 | 0.73 | 1.00 | 1.13 | 1.16 | 1.15 | 1.19 | NA | NA | NA | NA | NA | NA |
| DEOXYCYTIDINE MONOPHOSPHATE | ME1194831 | 0.87 | 0.90 | 0.74 | 1.01 | 0.70 | 1.00 | 1.08 | 1.23 | 1.18 | 1.29 | NA | NA | NA | NA | NA | NA |
| DIAMINOPIMELATE | ME1194833 | 1.16 | 1.00 | 1.05 | 1.15 | 0.94 | 0.93 | 0.93 | 0.92 | 0.97 | 0.96 | NA | NA | NA | NA | NA | NA |
| CITICOLINE | ME1194827 | 1.19 | 1.08 | 0.96 | 0.90 | 0.80 | 1.24 | 0.82 | 1.03 | 0.83 | 1.15 | NA | NA | NA | NA | NA | NA |
| DEOXYADENOSINE TRIPHOSPHATE | ME1194830 | 0.83 | 1.08 | 0.92 | 0.99 | 0.56 | 1.00 | 1.12 | 1.08 | 1.20 | 1.22 | NA | NA | NA | NA | NA | NA |
| ASPARTATE | ME1194823 | 0.98 | 1.06 | 0.99 | 1.05 | 0.84 | 1.02 | 1.04 | 0.98 | 1.00 | 1.05 | NA | NA | NA | NA | NA | NA |
| TAURINE | ME1194860 | 0.96 | 1.00 | 0.96 | 0.96 | 0.87 | 1.03 | 1.01 | 0.99 | 1.12 | 1.10 | NA | NA | NA | NA | NA | NA |
| GLUTAMATE | ME1194840 | 1.07 | 0.99 | 1.02 | 0.99 | 0.99 | 0.95 | 0.93 | 0.97 | 1.03 | 1.05 | NA | NA | NA | NA | NA | NA |
| 3-HYDROXYMETHYLGLUTARATE | ME1194812 | 1.26 | 0.98 | 0.88 | 1.16 | 0.49 | 0.85 | 1.05 | 1.08 | 1.08 | 1.16 | NA | NA | NA | NA | NA | NA |
| N-ACETYLNEURAMINATE | ME1194848 | 0.88 | 1.02 | 1.01 | 0.86 | 0.73 | 1.01 | 0.96 | 0.98 | 1.13 | 1.42 | NA | NA | NA | NA | NA | NA |
| AMINOISOBUTANOATE | ME1194819 | 0.93 | 0.95 | 1.01 | 0.97 | 0.75 | 0.98 | 1.03 | 1.03 | 1.15 | 1.19 | NA | NA | NA | NA | NA | NA |
| INOSINE MONOPHOSPHATE | ME1194843 | 1.04 | 1.00 | 0.89 | 0.97 | 0.73 | 1.06 | 0.94 | 1.05 | 1.07 | 1.25 | NA | NA | NA | NA | NA | NA |
| CYCLIC AMP | ME1194829 | 1.00 | 0.93 | 0.94 | 1.04 | 0.72 | 0.96 | 1.00 | 1.04 | 1.15 | 1.23 | NA | NA | NA | NA | NA | NA |
| ITACONATE | ME1194844 | 1.01 | 1.06 | 1.03 | 1.05 | 0.72 | 0.97 | 0.99 | 0.97 | 1.09 | 1.11 | NA | NA | NA | NA | NA | NA |
| ANSERINE | ME1194821 | 0.90 | 1.01 | 1.13 | 1.13 | 1.10 | 0.94 | 0.93 | 0.94 | 0.97 | 0.95 | NA | NA | NA | NA | NA | NA |
| CARNOSINE | ME1194825 | 0.95 | 1.12 | 1.21 | 1.02 | 0.88 | 0.94 | 0.96 | 0.89 | 1.00 | 1.03 | NA | NA | NA | NA | NA | NA |
| QUINOLINATE | ME1194857 | 0.96 | 0.81 | 0.65 | 0.99 | 0.99 | 0.91 | 1.00 | 1.23 | 1.15 | 1.31 | NA | NA | NA | NA | NA | NA |
| O-SUCCINYL-HOMOSERINE | ME1194852 | 1.37 | 1.02 | 0.82 | 1.18 | 0.52 | 0.96 | 1.10 | 0.96 | 1.08 | 1.00 | NA | NA | NA | NA | NA | NA |
| SALICYLATE | ME1194858 | 1.42 | 0.42 | 1.21 | 0.82 | 0.68 | 1.46 | 1.84 | 1.11 | 0.67 | 0.36 | NA | NA | NA | NA | NA | NA |
| DIHYDROOROTATE | ME1194834 | 0.91 | 0.99 | 1.10 | 1.20 | 0.78 | 0.87 | 0.97 | 1.07 | 1.07 | 1.04 | NA | NA | NA | NA | NA | NA |
| INOSINE | ME1194842 | 1.31 | 1.38 | 1.65 | 1.05 | 0.58 | 0.73 | 0.86 | 0.79 | 0.85 | 0.78 | NA | NA | NA | NA | NA | NA |
| TRANS-4-HYDROXY-L-PROLINE | ME1194862 | 1.24 | 0.86 | 0.96 | 1.26 | 0.73 | 0.84 | 0.81 | 1.08 | 0.96 | 1.27 | NA | NA | NA | NA | NA | NA |
| GLUCOSE 1-PHOSPHATE | ME1194838 | 0.92 | 0.85 | 0.69 | 1.02 | 0.66 | 0.98 | 1.01 | 1.38 | 1.29 | 1.19 | NA | NA | NA | NA | NA | NA |
| N-ACETYLASPARTATE | ME1194847 | 0.95 | 0.67 | 0.61 | 0.93 | 0.97 | 0.68 | 0.93 | 1.03 | 2.02 | 1.22 | NA | NA | NA | NA | NA | NA |
| NADP | ME1194850 | 0.92 | 1.15 | 0.97 | 1.06 | 0.53 | 0.88 | 1.18 | 1.14 | 1.05 | 1.12 | NA | NA | NA | NA | NA | NA |
| O-PHOSPHOETHANOLAMINE | ME1194851 | 1.01 | 1.08 | 0.91 | 1.08 | 0.67 | 0.95 | 0.99 | 1.02 | 1.08 | 1.21 | NA | NA | NA | NA | NA | NA |
| ALLOTHREONINE | ME1194818 | 1.05 | 0.39 | 0.47 | 1.30 | 0.55 | 0.17 | 0.72 | 1.28 | 2.05 | 2.03 | NA | NA | NA | NA | NA | NA |
| MALATE | ME1194846 | 1.01 | 1.03 | 0.97 | 1.01 | 0.79 | 1.04 | 0.98 | 1.01 | 1.02 | 1.14 | NA | NA | NA | NA | NA | NA |
| GUANIDINOSUCCINATE | ME1194841 | 1.02 | 0.74 | 0.58 | 0.95 | 1.11 | 0.70 | 1.00 | 1.07 | 1.47 | 1.36 | NA | NA | NA | NA | NA | NA |
| ADENOSINE-MONOPHOSPHATE | ME1194816 | 0.87 | 0.74 | 0.43 | 0.84 | 0.59 | 1.01 | 1.24 | 1.45 | 1.41 | 1.41 | NA | NA | NA | NA | NA | NA |
| ADP-GLUCOSE | ME1194817 | 0.85 | 0.97 | 0.91 | 0.89 | 0.59 | 1.13 | 1.14 | 1.10 | 1.19 | 1.23 | NA | NA | NA | NA | NA | NA |
| PTERIN | ME1194854 | 0.96 | 0.96 | 1.01 | 0.81 | 0.72 | 1.21 | 1.10 | 0.96 | 1.05 | 1.22 | NA | NA | NA | NA | NA | NA |
| ADENOSINE DIPHOSPHATE RIBOSE | ME1194815 | 0.80 | 1.11 | 0.89 | 1.12 | 0.41 | 1.00 | 1.16 | 1.10 | 1.20 | 1.21 | NA | NA | NA | NA | NA | NA |
| GLUCONATE | ME1194837 | 0.94 | 1.03 | 1.03 | 0.98 | 0.65 | 0.95 | 1.02 | 1.00 | 1.19 | 1.22 | NA | NA | NA | NA | NA | NA |
| ADENOSINE 3^,5^-DIPHOSPHATE | ME1194814 | 0.85 | 1.05 | 0.86 | 1.10 | 0.58 | 0.91 | 1.11 | 1.05 | 1.17 | 1.31 | NA | NA | NA | NA | NA | NA |
| PYROGLUTAMATE | ME1194856 | 1.15 | 0.77 | 0.91 | 1.22 | 1.02 | 0.87 | 1.02 | 0.98 | 1.00 | 1.06 | NA | NA | NA | NA | NA | NA |
| GAMMA-AMINOBUTYRATE | ME1194836 | 1.05 | 1.15 | 1.12 | 1.05 | 0.87 | 0.91 | 0.94 | 0.87 | 0.98 | 1.06 | NA | NA | NA | NA | NA | NA |
| L-ALANINE | ME1194845 | 1.00 | 1.03 | 0.96 | 1.15 | 0.72 | 0.89 | 1.03 | 1.06 | 1.12 | 1.04 | NA | NA | NA | NA | NA | NA |
| URATE | ME1194863 | 0.92 | 0.77 | 0.62 | 0.98 | 1.03 | 0.77 | 0.88 | 1.25 | 1.35 | 1.42 | NA | NA | NA | NA | NA | NA |
| ADENINE | ME1194813 | 0.96 | 0.92 | 0.74 | 1.05 | 1.06 | 0.91 | 1.04 | 1.14 | 1.10 | 1.08 | NA | NA | NA | NA | NA | NA |
| GLUCOSE 6-PHOSPHATE | ME1194839 | 0.97 | 1.03 | 1.12 | 0.95 | 0.76 | 1.13 | 1.05 | 1.05 | 1.07 | 0.86 | NA | NA | NA | NA | NA | NA |
| SUCCINATE | ME1194859 | 1.13 | 1.11 | 1.30 | 1.15 | 0.91 | 0.83 | 0.81 | 0.73 | 1.00 | 1.04 | NA | NA | NA | NA | NA | NA |
| ASPARAGINE | ME1194822 | 0.98 | 1.02 | 1.06 | 0.92 | 0.80 | 1.04 | 0.98 | 0.96 | 0.98 | 1.26 | NA | NA | NA | NA | NA | NA |
| PHOSPHOCREATINE | ME1194853 | 1.09 | 0.97 | 0.94 | 0.85 | 1.00 | 1.12 | 0.78 | 0.91 | 0.99 | 1.36 | NA | NA | NA | NA | NA | NA |
Factors:
| F1 | Treatment:BME-free (BSO) | Sample source:INS-1 cells | Injection order:10 |
| F2 | Treatment:BME-free (BSO) | Sample source:INS-1 cells | Injection order:11 |
| F3 | Treatment:BME-free (BSO) | Sample source:INS-1 cells | Injection order:3 |
| F4 | Treatment:BME-free (BSO) | Sample source:INS-1 cells | Injection order:4 |
| F5 | Treatment:BME-free (BSO) | Sample source:INS-1 cells | Injection order:7 |
| F6 | Treatment:BME-free (control) | Sample source:INS-1 cells | Injection order:12 |
| F7 | Treatment:BME-free (control) | Sample source:INS-1 cells | Injection order:13 |
| F8 | Treatment:BME-free (control) | Sample source:INS-1 cells | Injection order:14 |
| F9 | Treatment:BME-free (control) | Sample source:INS-1 cells | Injection order:5 |
| F10 | Treatment:BME-free (control) | Sample source:INS-1 cells | Injection order:6 |
| F11 | Treatment:MSe | Sample source:INS-1 cells | Injection order:17 |
| F12 | Treatment:MSe | Sample source:INS-1 cells | Injection order:18 |
| F13 | Treatment:MSe | Sample source:INS-1 cells | Injection order:19 |
| F14 | Treatment:quality control | Sample source:INS-1 cells | Injection order:15 |
| F15 | Treatment:quality control | Sample source:INS-1 cells | Injection order:2 |
| F16 | Treatment:quality control | Sample source:INS-1 cells | Injection order:8 |
