Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST004441)

(Analysis AN007437)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15	F16
D-Fructose 1-6-bisphosphate	ME1240329	0.06	0.28	0.09	0.18	2.03	4.58	3.45	2.63	0.43	0.66	0.53	0.37	0.19	0.16	0.14	0.23
Phosphocreatine	ME1240348	0.30	0.29	0.38	0.27	2.09	3.24	2.42	1.81	0.48	1.33	0.47	0.59	0.61	0.54	0.45	0.71
D-Hexose-phosphate	ME1240328	0.08	0.16	0.09	0.14	2.40	2.60	2.98	3.07	0.80	0.90	0.89	0.78	0.27	0.24	0.26	0.35
Mannitol/Sorbitol/Glucitol/Iditol	ME1240334	0.33	0.34	0.33	0.25	2.56	2.60	2.79	2.84	0.84	0.83	0.69	0.67	0.23	0.25	0.18	0.25
Inosine	ME1240320	0.00	0.14	0.11	0.12	0.00	0.00	1.97	1.98	0.00	1.67	1.89	0.00	1.48	2.25	2.67	1.70
NADP+	ME1240324	1.67	1.23	1.14	1.46	0.19	0.59	0.00	0.14	0.70	0.77	0.52	0.43	1.61	1.14	1.06	3.34
CTP	ME1240316	1.27	1.51	1.46	2.21	0.37	0.83	0.71	0.73	0.71	0.93	0.80	0.77	0.99	0.71	0.56	1.43
UDP-N-acetyl-D-glucosamine	ME1240346	1.46	2.23	1.75	2.34	0.53	0.54	0.69	0.62	0.56	0.86	0.77	0.67	0.77	0.73	0.55	0.92
5^-Phosphoribosyl-N-formylglycinamide	ME1240323	0.00	0.33	0.00	0.00	0.35	0.75	0.89	0.97	1.63	2.36	2.60	1.02	1.75	0.51	1.36	1.47
FA(18:2)	ME1240368	0.61	0.91	1.11	0.55	0.79	0.58	1.06	0.85	2.72	0.71	0.73	0.94	2.08	0.83	0.86	0.69
D-Arabitol/Xylitol/Ribitol	ME1240335	0.16	0.14	0.15	0.13	1.61	1.94	2.00	2.04	1.09	1.22	1.04	1.18	0.95	0.86	0.66	0.83
D-Glyceraldehyde 3-phosphate/Glycerone phosphate	ME1240330	0.06	0.23	0.09	0.08	1.88	1.83	1.71	2.30	1.03	1.26	1.04	1.13	0.77	0.76	0.79	1.05
2/3-Phospho-D-glycerate	ME1240331	0.10	0.68	0.07	0.34	1.05	1.60	1.59	1.28	1.22	1.36	1.00	0.63	1.27	1.40	0.79	1.63
2-Aminomuconate	ME1240352	0.23	0.29	0.30	0.35	1.35	0.87	1.13	1.91	1.26	1.61	1.59	0.92	0.82	1.12	0.66	1.59
Malate	ME1240339	0.20	0.26	0.20	0.19	0.99	0.90	1.35	1.55	1.59	1.93	1.55	1.44	1.13	0.92	0.81	0.98
Fumarate	ME1240338	0.20	0.25	0.23	0.17	0.90	1.50	1.49	1.39	1.57	1.95	1.32	1.38	0.98	0.86	0.80	1.02
Allantoate	ME1240322	0.28	0.49	0.42	0.44	0.92	1.35	1.43	1.39	1.41	1.72	1.07	1.11	1.05	0.95	0.97	1.00
trans-4-Hydroxy-L-proline	ME1240349	0.44	0.38	0.24	0.22	0.83	1.37	1.31	1.59	1.41	1.89	1.14	1.02	1.29	0.95	0.67	1.25
Dehydroascorbate	ME1240344	0.46	0.41	0.34	0.88	0.59	0.44	0.32	1.00	0.63	2.30	1.82	1.53	1.50	1.13	1.08	1.57
Ascorbate	ME1240343	0.44	0.63	0.40	0.63	1.45	0.32	1.07	0.51	1.33	0.96	0.99	1.54	1.80	1.42	1.37	1.14
Glutathione disulfide	ME1240342	0.27	0.55	0.39	0.48	1.19	1.07	1.18	1.03	1.24	1.38	1.39	1.23	1.07	1.04	1.07	1.44
CMP-N-acetylneuraminate	ME1240347	0.57	0.75	0.48	0.71	1.10	0.41	1.20	0.90	1.18	1.28	1.24	1.13	1.45	1.34	0.97	1.28
Sphingosine 1-phosphate	ME1240374	0.45	0.56	0.66	0.30	0.85	0.55	0.93	0.69	1.37	1.30	1.54	1.45	1.24	1.26	1.35	1.51
Dimethylglycine	ME1240345	0.36	0.53	0.29	0.44	0.42	0.73	0.95	1.20	1.08	1.99	1.27	1.31	1.57	0.67	1.70	1.51
Hypoxanthine	ME1240321	0.62	0.60	0.37	0.61	0.50	0.98	0.83	1.05	1.15	1.86	1.51	0.95	1.48	0.93	0.65	1.90
Taurine	ME1240351	0.21	0.70	0.21	0.35	0.37	1.03	1.12	1.16	1.26	1.65	1.23	1.17	1.75	1.28	0.53	1.98
AMP	ME1240312	0.25	0.42	0.21	0.47	0.55	0.47	0.77	0.53	1.19	1.94	1.81	1.34	1.54	1.49	0.92	2.09
2-Oxoglutarate	ME1240336	0.47	0.52	0.22	0.56	0.70	0.69	0.81	0.81	1.35	1.42	1.20	1.01	2.06	1.24	1.17	1.80
2-Hydroxyglutarate	ME1240340	0.34	0.54	0.45	0.51	0.61	0.67	0.75	0.78	1.10	1.56	1.17	1.05	1.88	1.42	1.54	1.62
Glycerol 3-phosphate	ME1240353	0.37	0.70	0.50	0.54	0.51	0.58	0.70	0.71	1.27	1.72	1.34	1.15	1.59	1.28	1.38	1.68
Pyruvate	ME1240332	0.49	0.73	0.65	0.63	1.44	1.59	1.79	0.97	1.45	0.74	1.47	0.60	0.88	1.07	0.79	0.71
FA(18:0)	ME1240364	0.95	1.43	1.26	1.08	0.95	1.01	1.19	1.09	1.12	0.79	0.87	0.94	1.25	1.07	0.02	0.99
GDP	ME1240315	0.31	0.64	0.64	0.95	0.57	0.64	0.93	0.91	1.03	1.55	1.28	0.98	1.65	0.98	1.04	1.91
GTP	ME1240314	0.69	0.82	0.70	1.20	0.39	0.61	0.88	0.85	1.05	1.45	1.26	0.94	1.41	1.05	0.73	1.99
ADP	ME1240311	0.60	1.20	0.75	1.08	0.51	0.84	0.75	0.62	1.10	1.40	1.33	0.86	1.16	1.19	0.92	1.69
UDP	ME1240319	0.73	1.13	0.81	1.27	0.51	0.75	0.64	0.69	0.89	1.38	1.13	0.86	1.38	1.11	1.02	1.70
Glutathione	ME1240341	0.49	0.99	0.70	0.85	0.63	1.08	1.01	1.13	1.06	1.37	1.03	0.72	1.33	1.02	1.08	1.52
Pantothenate	ME1240350	0.69	0.91	0.70	0.89	0.74	1.00	0.75	0.87	1.19	1.08	1.44	0.88	1.29	1.21	0.91	1.45
ATP	ME1240310	0.53	1.49	0.63	1.53	0.28	0.62	0.91	0.85	1.00	1.54	1.14	0.75	1.24	1.01	0.61	1.87
CDP	ME1240317	0.95	1.18	1.05	1.48	0.74	0.74	0.77	0.66	0.94	1.09	1.14	0.82	1.38	1.08	0.74	1.23
UTP	ME1240318	0.85	1.32	1.02	1.74	0.51	0.80	0.71	0.80	0.83	1.13	0.99	0.76	1.15	1.13	0.77	1.47
FA(5:0)	ME1240355	1.19	1.01	0.89	1.27	0.66	1.38	1.15	0.91	1.17	1.25	1.04	0.75	0.83	0.63	1.35	0.52
Diphosphate	ME1240326	1.50	1.05	1.36	1.26	1.08	1.02	0.83	1.00	0.91	0.83	0.82	1.04	0.81	0.74	0.96	0.81
FA(8:0)	ME1240358	0.76	1.36	1.02	1.25	0.97	1.14	0.70	0.77	0.80	0.85	0.95	0.67	1.13	1.03	1.39	1.21
Sphinganine 1-phosphate	ME1240375	0.67	1.09	0.83	1.20	0.87	0.91	1.20	1.04	1.39	0.64	0.75	0.78	1.15	0.95	1.50	1.02
FA(10:0)	ME1240360	1.08	1.07	1.18	0.85	1.17	1.11	1.08	0.76	1.00	1.01	1.01	0.65	0.96	1.06	1.03	0.97
FA(7:0)	ME1240357	1.13	1.08	1.26	0.77	1.05	1.28	1.02	0.81	1.01	0.99	1.10	0.68	0.92	1.01	1.03	0.84
FA(6:0)	ME1240356	0.96	1.16	1.06	1.02	1.08	1.05	1.09	0.87	1.10	0.92	0.94	0.89	0.92	1.03	0.97	0.93
Phosphate	ME1240325	1.16	1.08	1.12	1.04	0.94	1.02	0.93	0.98	0.97	0.98	0.92	0.92	0.97	1.04	0.96	0.96
FA(12:0)	ME1240361	0.82	1.35	1.01	0.73	1.00	0.86	1.35	0.78	1.29	0.89	0.89	0.74	1.20	0.91	1.26	0.90
FA(14:0)	ME1240362	0.95	1.17	0.95	0.96	0.94	0.89	1.03	0.87	1.15	0.89	0.94	0.91	1.00	1.04	1.36	0.94
FA(16:0)	ME1240363	1.01	1.21	1.10	0.90	0.85	0.88	0.95	0.98	1.26	0.82	0.80	0.91	1.08	0.95	1.32	0.97
Adenine	ME1240313	1.06	1.20	0.63	0.84	1.05	1.01	0.96	1.14	1.02	1.18	1.03	0.59	1.23	1.10	1.19	0.78
Phosphoethanolamine	ME1240354	0.73	0.87	0.62	0.94	0.97	0.85	1.14	0.86	0.98	1.42	1.08	1.00	1.28	0.95	1.08	1.22
FA(14:1)	ME1240365	0.82	0.78	0.80	0.66	0.92	0.87	1.06	1.08	1.16	1.09	1.11	0.90	1.19	1.15	1.39	1.04
FA(16:1)	ME1240366	0.76	1.11	0.76	0.81	1.20	0.93	0.84	0.96	1.07	1.10	1.07	1.04	1.08	0.92	1.32	1.03
FA(18:1)	ME1240367	0.86	0.94	0.96	0.85	1.06	1.03	1.16	1.06	1.12	1.06	0.98	1.02	0.96	0.85	1.07	1.01
FA(9:0)	ME1240359	0.67	0.97	0.80	0.89	1.02	1.05	1.19	1.00	1.07	1.12	1.08	0.93	1.04	1.01	1.08	1.08
FA(20:5)	ME1240370	0.66	0.82	0.69	0.73	2.04	1.12	1.23	1.44	0.84	1.23	1.05	1.01	0.86	0.58	0.91	0.78
FA(20:3)	ME1240372	0.54	0.72	0.46	0.83	1.80	0.92	0.88	1.18	1.07	1.10	1.33	1.08	0.89	0.77	1.22	1.22
FA(22:5)	ME1240373	0.56	0.92	0.63	0.89	1.40	0.99	1.03	1.29	0.80	1.19	1.14	1.17	1.13	0.77	1.18	0.89
FA(20:4)	ME1240369	0.69	0.82	0.68	0.71	1.62	0.92	1.18	1.13	0.98	1.22	1.18	1.02	0.93	0.78	1.01	1.12
FA(22:6)	ME1240371	0.80	1.01	0.76	0.92	1.55	1.02	1.10	1.13	1.04	1.04	1.11	0.86	0.91	0.74	0.93	1.08
Succinate	ME1240337	0.77	0.80	0.81	0.69	0.85	1.01	0.87	1.05	1.63	1.48	1.56	0.85	0.70	1.02	0.87	1.03
Lactate	ME1240333	0.69	0.73	0.68	0.69	0.93	1.09	1.06	1.11	1.52	1.31	1.45	1.47	0.84	0.81	0.74	0.87
L-aspartate	ME1240308	0.63	0.47	0.39	0.61	1.16	1.22	1.16	1.45	1.53	1.55	1.29	1.35	0.90	0.76	0.78	0.75
D-Glucose	ME1240327	0.80	0.80	0.92	0.82	1.30	1.13	1.16	1.09	1.20	1.47	1.05	0.98	0.86	0.82	0.75	0.85
L-methionine	ME1240309	0.55	0.45	0.86	0.55	1.16	1.14	1.25	1.08	1.19	1.49	1.40	1.13	1.27	1.05	0.54	0.90

Factors:

F1	Treatment:100 nM HHT \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:12
F2	Treatment:100 nM HHT \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:19
F3	Treatment:100 nM HHT \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:24
F4	Treatment:100 nM HHT \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:4
F5	Treatment:100 nM OT82 \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:21
F6	Treatment:100 nM OT82 \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:31
F7	Treatment:100 nM OT82 \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:32
F8	Treatment:100 nM OT82 \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:6
F9	Treatment:1 nM OT82 \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:13
F10	Treatment:1 nM OT82 \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:16
F11	Treatment:1 nM OT82 \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:17
F12	Treatment:1 nM OT82 \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:3
F13	Treatment:Untreated \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:10
F14	Treatment:Untreated \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:18
F15	Treatment:Untreated \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:22
F16	Treatment:Untreated \| Timepoint:24h \| Sample source:MDS-L Cells \| Injection order:7

Data matrix