Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003822)

(Analysis AN007474)

Metabolite	Structure	F1	F2	F3	F4
aspartate	ME1250648	1.87	0.77	0.43	0.53
threonine	ME1250711	1.69	0.69	0.64	0.65
succinyl.CoA	ME1250709	1.51	1.25	0.29	0.72
trans.urocanate	ME1250712	1.26	1.46	0.70	0.66
adenine	ME1250641	1.03	0.88	1.35	0.85
homocitrulline	ME1250678	0.89	1.00	1.20	1.01
AMP	ME1250644	0.90	0.93	1.24	1.02
kynurenine	ME1250682	0.89	0.87	1.23	1.06
beta.alanine	ME1250650	0.82	0.92	1.20	1.12
fumarate	ME1250667	0.84	0.86	1.29	1.08
malate	ME1250685	0.83	0.89	1.25	1.10
succinate	ME1250708	0.79	0.74	1.33	1.17
NADH	ME1250691	0.69	0.97	1.27	1.19
argininosuccinate	ME1250646	0.71	0.89	1.36	1.17
GMP	ME1250674	0.72	0.95	1.36	1.13
Glycerophosphocholine	ME1250672	1.23	1.09	0.72	0.86
CDP	ME1250655	1.16	1.10	0.82	0.88
UDP	ME1250716	1.17	1.07	0.84	0.87
phosphocholine	ME1250697	1.12	1.09	0.85	0.92
ADP	ME1250642	1.12	1.03	0.88	0.92
glycine	ME1250673	1.11	1.04	0.84	0.95
citrate	ME1250657	0.91	1.15	0.95	1.04
arginine	ME1250645	1.05	0.97	0.96	0.99
citrulline	ME1250658	1.01	0.99	0.97	1.02
Acetyl.CoA	ME1250639	1.03	1.02	0.99	0.97
S.Adenosyl.L.Homocysteine	ME1250703	1.05	1.01	0.98	0.95
GSSG	ME1250676	1.05	1.02	0.95	0.97
GSH_Ellmans	ME1250675	1.05	1.04	0.92	0.97
NAD.	ME1250690	1.06	1.04	0.92	0.97
cis.aconitate	ME1250656	0.97	1.11	0.88	1.03
fructose	ME1250666	0.99	1.04	0.89	1.05
mannose	ME1250686	0.99	1.04	0.89	1.05
methylthioadenosine	ME1250689	0.98	1.11	1.01	0.96
Pyridoxine	ME1250702	1.01	1.09	0.93	0.98
carnitine	ME1250653	0.95	1.06	0.96	1.04
xanthosine	ME1250720	0.96	1.09	0.93	1.03
FAD	ME1250664	0.97	1.04	0.99	1.02
Butyrylcarnitine	ME1250651	1.00	1.06	0.99	0.98
S.Adenosyl.L.methionine	ME1250704	1.00	1.04	0.95	1.00
GDP	ME1250668	0.91	1.04	1.00	1.07
proline	ME1250700	0.87	1.05	1.06	1.07
UMP	ME1250717	0.97	1.04	1.11	0.95
taurine	ME1250710	0.95	1.00	1.06	1.03
creatine	ME1250659	0.98	0.97	1.07	1.00
acetylcarnitine	ME1250640	0.97	0.99	1.05	1.01
asymmetric.dimethylarginine	ME1250649	0.98	0.99	1.05	1.00
carnosine	ME1250654	1.09	0.87	1.10	0.92
alanine	ME1250643	1.06	0.84	1.10	0.97
sarcosine	ME1250705	1.06	0.84	1.10	0.97
Cysteine_Ellmans_conjugated	ME1250660	1.16	0.83	1.00	0.92
phosphocreatine	ME1250698	1.19	0.90	1.00	0.86
valine	ME1250719	1.13	0.96	1.01	0.89
hypotaurine	ME1250679	1.11	0.93	1.03	0.91
isoleucine	ME1250681	1.11	0.92	1.04	0.92
leucine	ME1250683	1.06	0.98	1.02	0.94
histidine	ME1250677	1.08	0.96	0.99	0.95
NADP	ME1250692	1.07	0.95	1.01	0.95
lysine	ME1250684	1.11	0.93	0.95	0.95
Methionine.sulfoxide	ME1250687	1.10	0.96	0.98	0.92
NADPH	ME1250693	1.12	0.97	0.95	0.92
asparagine	ME1250647	1.14	0.96	0.88	0.94
cystathionine	ME1250661	1.13	0.97	0.91	0.93
ornithine	ME1250695	1.11	0.97	0.91	0.95
tryptophan	ME1250713	1.13	0.88	0.91	0.97
2-hydroxyglutarate	ME1250636	1.16	0.91	0.88	0.94
methionine	ME1250688	1.20	0.87	0.88	0.92
palmitate	ME1250696	1.02	0.81	0.70	1.22
2-oxobutyric_acid	ME1250637	0.95	0.96	0.84	1.15
niacinamide	ME1250694	1.05	1.03	0.77	1.05
propionylcarnitine	ME1250701	1.29	1.17	0.55	0.85
tyrosine	ME1250714	1.26	0.88	0.87	0.86
glutamate	ME1250669	1.27	0.98	0.80	0.84
UDP.GlcNAc	ME1250715	1.29	0.95	0.84	0.82
glutamine	ME1250670	1.41	0.92	0.71	0.78
serine	ME1250707	1.35	0.82	0.78	0.85
Sedoheptulose.7.phosphate	ME1250706	0.44	1.39	1.11	1.31
3-phosphoglycerate	ME1250638	0.49	1.57	0.78	1.33
F6P_or_G1P	ME1250663	0.51	1.41	0.91	1.33
Fructose.1.6.bisphosphate	ME1250665	0.83	1.50	0.68	1.09
phosphoenolpyruvate	ME1250699	0.62	1.81	0.56	1.19
IMP	ME1250680	0.18	0.99	1.59	1.53
dihydroxyacetone_phosphate	ME1250662	0.31	1.17	1.46	1.38
Glycerol.3.Phosphate	ME1250671	0.39	0.99	1.48	1.37
C5.Carnitines	ME1250652	0.59	0.53	1.75	1.27
Carbamoyl Aspartic Acid	ME1250718	0.37	NA	1.47	1.16
dihydroorotate	ME1250721	0.29	NA	2.08	1.25

Factors:

F1	Sample source:SEM leukemia cells \| guideRNA:Intergenic1 \| overexpression:RFP
F2	Sample source:SEM leukemia cells \| guideRNA:SLC31A1 guide #2 \| overexpression:AOX
F3	Sample source:SEM leukemia cells \| guideRNA:SLC31A1 guide #2 \| overexpression:RFP
F4	Sample source:SEM leukemia cells \| guideRNA:SLC31A1 guide #7 \| overexpression:AOX

Data matrix