Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003825)

(Analysis AN007477)

Metabolite	Structure	F1	F2	F3	F4
Carbamoyl Aspartic Acid	ME1250993	NA	0.83	0.15	2.01
dihydroorotate	ME1250995	0.11	1.09	0.09	2.41
Glycerol.3.Phosphate	ME1250951	0.17	1.05	0.46	2.31
C5.Carnitines	ME1250931	0.38	0.53	1.03	2.05
IMP	ME1250959	0.32	0.57	0.59	2.52
dihydroxyacetone_phosphate	ME1250942	0.47	0.82	1.03	1.67
NADH	ME1250970	0.63	1.07	0.85	1.45
Glycerophosphocholine	ME1250952	1.21	1.41	0.74	0.63
alanine	ME1250923	1.23	0.61	1.35	0.80
sarcosine	ME1250984	1.24	0.61	1.35	0.80
Cysteine_Ellmans_conjugated	ME1250940	0.91	0.89	1.36	0.84
acetylcarnitine	ME1250921	1.02	0.77	1.35	0.86
niacinamide	ME1250973	1.05	0.74	1.33	0.88
carnosine	ME1250933	0.71	0.99	1.35	0.94
kynurenine	ME1250961	0.77	0.92	1.22	1.08
beta.alanine	ME1250929	0.99	0.71	1.18	1.11
succinate	ME1250986	0.77	0.84	1.14	1.26
leucine	ME1250962	0.94	1.31	0.77	0.98
glutamate	ME1250948	1.04	1.23	0.88	0.85
phosphocholine	ME1250976	1.04	1.24	0.84	0.89
Acetyl.CoA	ME1250920	0.95	1.18	0.97	0.90
GSSG	ME1250955	0.96	1.21	0.92	0.91
NADP	ME1250971	0.97	1.19	0.93	0.91
isoleucine	ME1250960	0.88	1.24	0.87	1.00
phosphocreatine	ME1250977	0.94	1.23	0.86	0.97
ADP	ME1250922	0.94	1.20	0.90	0.96
palmitate	ME1250975	0.96	1.17	0.89	0.99
asymmetric.dimethylarginine	ME1250928	1.06	1.06	0.95	0.92
S.Adenosyl.L.methionine	ME1250983	1.05	1.08	0.94	0.93
FAD	ME1250943	1.03	1.10	0.96	0.91
Methionine.sulfoxide	ME1250966	1.02	1.13	0.94	0.91
creatine	ME1250938	0.98	1.11	0.96	0.96
GSH_Ellmans	ME1250954	1.01	1.10	0.95	0.94
histidine	ME1250956	1.01	1.10	0.95	0.94
NADPH	ME1250972	1.08	1.13	0.90	0.90
trans.urocanate	ME1250988	1.06	1.12	0.90	0.91
methionine	ME1250967	1.03	1.16	0.95	0.86
tyrosine	ME1250990	1.05	1.15	0.93	0.86
ornithine	ME1250974	1.02	1.13	1.03	0.82
tryptophan	ME1250989	1.03	1.12	0.99	0.86
cystathionine	ME1250941	0.99	1.06	1.02	0.93
arginine	ME1250924	1.06	1.07	0.99	0.89
glycine	ME1250953	1.05	1.03	1.03	0.89
NAD.	ME1250969	1.06	1.05	1.02	0.87
Fructose.1.6.bisphosphate	ME1250944	1.13	1.13	0.95	0.79
S.Adenosyl.L.Homocysteine	ME1250982	1.13	1.06	1.04	0.77
3-phosphoglycerate	ME1250919	1.11	1.04	1.01	0.84
threonine	ME1250987	1.10	1.06	1.03	0.82
cis.aconitate	ME1250935	1.19	1.05	0.88	0.88
asparagine	ME1250926	1.07	1.12	0.85	0.96
xanthosine	ME1250994	1.06	1.09	0.86	1.00
citrulline	ME1250937	1.05	1.02	0.94	0.99
glycerate	ME1250950	1.17	0.98	0.87	0.97
fructose	ME1250945	1.11	1.02	0.86	1.00
mannose	ME1250965	1.11	1.03	0.86	1.00
GDP	ME1250947	0.94	1.06	0.88	1.12
carnitine	ME1250932	0.80	1.04	0.98	1.17
proline	ME1250979	0.85	1.05	0.97	1.13
homocitrulline	ME1250957	0.92	1.05	1.01	1.01
lysine	ME1250963	0.98	1.04	1.12	0.85
methylthioadenosine	ME1250968	1.05	0.97	1.07	0.91
creatinine	ME1250939	0.96	0.98	1.08	0.97
Pyridoxine	ME1250981	1.00	0.95	1.08	0.97
argininosuccinate	ME1250925	1.00	0.87	1.05	1.09
Butyrylcarnitine	ME1250930	0.98	0.93	1.04	1.05
fumarate	ME1250946	0.96	0.87	1.11	1.06
malate	ME1250964	1.03	0.86	1.09	1.02
2-hydroxyglutarate	ME1250918	1.02	0.97	0.94	1.07
hypotaurine	ME1250958	1.06	0.90	0.92	1.12
UDP.GlcNAc	ME1250991	1.59	0.79	1.17	0.45
phosphoenolpyruvate	ME1250978	1.45	0.98	1.13	0.44
UDP	ME1250992	1.45	0.84	1.13	0.58
propionylcarnitine	ME1250980	1.16	0.91	1.16	0.78
serine	ME1250985	1.14	0.96	1.16	0.74
CDP	ME1250934	1.36	0.92	1.08	0.64
citrate	ME1250936	1.31	0.97	1.01	0.70
aspartate	ME1250927	1.28	1.25	1.03	0.45
glutamine	ME1250949	1.19	1.16	0.97	0.67

Factors:

F1	Sample source:SEM leukemia cells \| sgRNA:Intergenic1 \| treatment2:PyruvateAndUridine
F2	Sample source:SEM leukemia cells \| sgRNA:Intergenic1 \| treatment2:Vehicle
F3	Sample source:SEM leukemia cells \| sgRNA:SLC31A1 guide #2 \| treatment2:PyruvateAndUridine
F4	Sample source:SEM leukemia cells \| sgRNA:SLC31A1 guide #2 \| treatment2:Vehicle

Data matrix