Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Rat HCR/LCR Stamina Study (Study ST000017)

LC/Electro-spray /QTOF negative ion mode (Analysis AN000035)

Metabolite	Structure	F1	F2	F3	F4
DEOXYCORTICOSTERONE ACETATE	ME645169	0.30	3.71	0.64	0.94
(S)-DIHYDROOROTATE	ME645059	NA	0.19	2.65	0.16
3-NITRO-L-TYROSINE	ME645099	1.84	0.47	1.47	0.34
4-HYDROXYBENZALDEHYDE	ME645108	0.92	NA	1.08	NA
MERCAPTOPYRUVATE	ME645229	1.07	NA	0.93	NA
INOSINE	ME645218	0.92	0.77	1.78	0.47
DIHYDROXYACETONE PHOSPHATE	ME645175	0.86	0.89	1.51	NA
DIETHYL 2-METHYL-3-OXOSUCCINATE	ME645171	0.82	0.94	1.12	NA
THIOPURINE S-METHYLETHER	ME645289	0.99	0.80	1.21	NA
3-HYDROXYBENZALDEHYDE	ME645091	1.27	1.03	0.78	NA
GLYCEROL PHOSPHATE	ME645195	1.19	1.01	0.80	NA
6-PHOSPHOGLUCONIC ACID	ME645120	0.96	1.37	0.84	NA
BEHENIC ACID	ME645142	1.05	1.32	0.79	NA
ANANDAMIDE	ME645131	1.18	0.68	0.60	1.77
CYSTATHIONINE	ME645166	0.95	0.93	0.70	1.82
4-HYDROXYPHENYLACETATE	ME645109	1.40	0.51	0.63	1.14
AZELAIC ACID	ME645140	1.47	0.62	0.74	1.55
CHOLESTEROL SULFATE	ME645158	1.28	1.17	0.73	1.01
ASPARTATE	ME645139	1.07	1.16	0.58	1.18
GLYCOCHOLATE	ME645196	1.06	1.23	0.59	1.15
GLYCODEOXYCHOLATE / GLYCOCHENODEOXYCHOLATE	ME645197	1.04	1.21	0.58	1.17
INDOLEPROPIONATE	ME645217	1.13	1.30	0.81	0.75
PROSTAGLANDIN G2	ME645268	1.07	1.26	0.85	0.67
CITRULLINE	ME645162	1.05	1.22	0.86	0.83
THYMIDINE	ME645291	1.03	1.14	0.91	0.71
THYROTROPIN RELEASING HORMONE	ME645292	1.14	1.11	0.81	0.76
N-METHYLTRYPTAMINE	ME645244	1.13	1.06	0.93	0.82
ARGININE	ME645138	1.08	1.10	0.91	0.88
[C13] PHENYLALANINE	ME645062	1.05	1.10	0.89	0.87
15(S)-HETE	ME645068	0.91	1.26	0.84	0.83
PALMITIC ACID	ME645255	0.88	1.30	0.84	0.77
5-OXO-PROLINE	ME645117	1.02	1.24	0.70	1.04
MYRISTOLEIC ACID	ME645233	0.97	1.26	0.80	0.96
DOPAMINE 3-O-SULFATE	ME645181	1.40	1.01	0.92	0.78
GLUTAMIC ACID	ME645192	1.35	0.91	0.95	0.80
GLYCOLITHOCHOLIC ACID ETHYL ESTER	ME645198	1.19	0.99	0.95	0.75
ARACHIDONATE	ME645135	1.21	1.09	0.80	0.90
UROCORTISONE	ME645299	1.29	1.03	0.86	0.82
N-ACETYLNEURAMINATE	ME645240	1.23	0.87	1.06	0.84
STEAROYLGLYCEROPHOSPHOETHANOLAMINE	ME645283	1.22	0.79	1.09	0.94
ACETYLENEDICARBOXYLATE	ME645123	1.19	0.80	1.12	0.86
INDOLE-3-ACETIC ACID	ME645216	1.24	0.80	1.12	0.86
GAMMA-LINOLENIC ACID	ME645189	1.28	0.94	0.84	1.00
MALONATE	ME645227	1.20	0.84	0.95	1.09
GULONO-1,4-LACTONE	ME645202	1.25	0.87	0.97	1.01
XYLONATE	ME645303	1.22	0.92	0.96	1.06
HEPTANOIC ACID	ME645203	0.83	1.07	1.14	0.88
3ALPHA-HYDROXY-5BETA-CHOLANATE	ME645087	0.81	1.14	0.92	1.10
DECANOATE	ME645167	0.90	1.14	0.91	1.03
3-METHYL-2-OXOVALERIC ACID	ME645097	0.88	1.13	1.02	0.91
N-ACETYLGLYCINE	ME645238	0.87	1.21	0.92	0.90
DOCOSAHEXAENOIC ACID	ME645177	1.04	0.89	1.02	0.82
3-METHYL-2-OXINDOLE	ME645095	0.95	0.99	1.07	0.94
PROSTAGLANDIN E1	ME645267	0.93	0.97	1.10	0.96
THREONATE	ME645290	0.97	1.01	1.07	0.90
TRIDECANOIC ACID	ME645294	1.00	1.04	1.02	0.90
3ALPHA,7ALPHA,12ALPHA,26-TETRAHYDROXY-5BETA-CHOLESTANE	ME645084	1.00	0.97	0.98	1.08
N(PAI)-METHYL-L-HISTIDINE	ME645234	0.99	0.93	1.02	1.09
GLUTAMINE	ME645193	1.01	1.03	0.93	1.04
BOC-ASP-OH	ME645147	1.01	0.97	1.03	0.99
CIS-7,10,13,16-DOCOSATETRAENOIC ACID	ME645160	1.04	0.99	0.96	1.02
2-OXO-3-HYDROXY-4-PHOSPHOBUTANOATE	ME645077	0.99	0.99	0.99	1.03
5-HYDROXYINDOLE-3-ACETIC ACID	ME645115	1.01	1.01	0.99	0.99
BOC-PHE-OH	ME645149	1.01	1.01	0.99	1.00
BOC-PRO-OH	ME645150	0.95	1.06	0.95	1.01
CAPRYLIC ACID	ME645152	0.93	1.07	0.99	0.98
AMINOBUTANOIC ACID	ME645128	1.06	1.01	0.95	0.92
[C13] TYROSINE	ME645063	1.05	1.08	0.93	0.93
9(10)-EPOME	ME645122	1.00	1.06	0.95	0.98
5,6-DIHYDROURACIL	ME645113	1.00	1.05	0.99	0.94
BOC-ASN	ME645146	1.01	1.05	0.98	0.93
[C13] METHIONINE	ME645061	1.03	1.06	0.96	0.95
[C13] VALINE	ME645064	1.04	1.04	0.97	0.94
ARACHIDONOYLGLYCEROPHOSPHOINOSITOL	ME645137	1.09	0.89	1.09	0.94
PHENYLACETATE	ME645260	1.06	0.86	1.13	0.96
4-VINYLPHENOL SULFATE	ME645112	1.02	0.86	1.18	0.94
TAUROCHENODEOXYCHOLATE	ME645285	1.08	0.83	1.19	0.91
3-METHYLADENINE	ME645098	1.11	1.00	1.01	0.96
CITRATE	ME645161	1.06	0.91	1.06	0.99
THYROXINE	ME645293	1.08	0.94	1.02	0.98
TAURINE	ME645284	1.15	0.88	1.00	1.00
2-OXOADIPATE	ME645078	1.05	0.83	1.03	1.06
HYDROXYISOVALERATE	ME645213	1.08	0.87	1.02	1.06
AMINOHYDROXYBUTANOIC ACID	ME645129	1.12	0.85	1.02	1.05
ARACHIDONOYLGLYCEROPHOSPHOETHANOLAMINE	ME645136	1.12	0.87	1.03	1.05
PALMITOYLGLYCEROPHOSPHOETHANOLAMINE / PALMITOYLPLASMENYLETHANOLAMINE	ME645256	1.07	0.89	0.99	1.10
PENTITOL	ME645259	1.05	0.91	1.04	1.06
FORMYLANTHRANILATE	ME645184	1.15	0.93	0.84	1.35
OLEOYLGLYCEROPHOSPHOETHANOLAMINE	ME645250	1.05	0.99	0.91	1.10
TAUROLITHOCHOLATE	ME645287	1.09	1.02	0.84	1.09
FORMYL-L-METHIONINE	ME645185	0.98	0.99	0.83	1.18
STEARIDONATE	ME645282	1.00	1.06	0.85	1.09
5-HYDROXY-L-TRYPTOPHAN	ME645116	0.99	1.04	0.89	1.14
GLYOXYLATE	ME645200	0.99	0.98	0.88	1.12
4-HYDROXY-2-QUINOLINECARBOXYLIC ACID	ME645105	1.09	0.89	0.90	1.20
PHOSPHO(ENOL)PYRUVIC ACID	ME645262	1.05	0.90	0.82	1.19
ALPHA-TOCOPHEROL	ME645127	1.01	0.94	0.87	1.30
SPHINGOSINE 1-PHOSPHATE	ME645280	0.96	0.97	0.93	1.23
N-OLEOYLGLYCINE	ME645245	0.66	0.61	1.55	0.87
ACONITATE	ME645124	0.85	0.76	1.35	1.02
GLUCURONOLACTONE	ME645191	0.76	0.84	1.31	1.00
4-AMINOBENZOATE	ME645103	0.93	0.83	1.12	1.11
ORNITHINE	ME645251	0.98	0.87	1.06	1.14
SERINE	ME645278	1.02	0.83	1.06	1.15
(S)-LACTATE	ME645060	1.00	0.77	1.06	1.26
4-OXOGLUTARAMATE	ME645110	1.01	0.79	1.08	1.19
CORTICOSTERONE	ME645163	1.00	0.79	1.08	1.21
HEXURONIC ACID	ME645208	1.08	0.80	1.04	1.15
S-HEXYL-GLUTATHIONE	ME645279	1.12	0.79	1.08	1.21
3,4-DIHYDROXYBENZOATE	ME645082	0.92	0.72	1.16	1.18
AMINOPENTANOIC ACID	ME645130	1.03	0.72	1.20	1.10
ISOLEUCINE/LEUCINE	ME645220	1.01	0.71	1.20	1.08
11-BETA-HYDROXYANDROST-4-ENE-3,17-DIONE	ME645066	0.76	0.98	1.05	1.14
ESTRADIOL-17BETA	ME645183	0.83	1.03	1.11	1.10
TESTOSTERONE	ME645288	0.80	0.99	1.09	1.07
NONANOATE	ME645247	0.85	0.90	1.19	1.07
3-METHYL-2-OXOBUTANOIC ACID	ME645096	0.93	0.93	1.10	1.06
URATE	ME645297	0.91	0.90	1.14	1.05
HEXADECANEDIOATE	ME645205	0.90	1.02	1.04	1.19
CHOLESTEROL	ME645157	0.81	1.02	0.98	1.20
2-HYDROXYBUTYRIC ACID	ME645074	0.82	0.95	1.00	1.28
3ALPHA,7ALPHA-DIHYDROXY-5BETA-CHOLESTANATE	ME645086	0.86	0.98	1.00	1.24
HEXANOATE	ME645206	0.91	0.88	0.99	1.30
PALMITOYLGLYCEROPHOSPHOINOSITOL	ME645257	0.86	0.88	1.09	1.23
HYPOXANTHINE	ME645214	0.89	0.86	1.08	1.22
TRYPTOPHAN	ME645295	0.89	0.86	1.10	1.20
4-ACETAMIDOBUTANOATE	ME645102	0.84	0.84	1.09	1.31
DODECANEDIOATE	ME645179	0.79	0.86	1.14	1.25
INDICAN	ME645215	0.96	0.75	1.04	1.45
URACIL	ME645296	0.88	0.78	1.07	1.37
PYRUVATE	ME645272	0.81	0.81	1.05	1.46
LINOLEOYLGLYCEROPHOSPHOETHANOLAMINE	ME645225	0.77	0.83	1.09	1.40
N-ACETYL-D-TRYPTOPHAN	ME645237	0.77	0.80	1.08	1.38
7-ALPHA-HYDROXY-3-OXO-4-CHOLESTENOATE	ME645121	0.70	0.84	1.31	1.30
DIHEXOSE	ME645172	0.66	0.74	1.24	1.34
2-HYDROXYGLUTARATE	ME645075	0.71	0.86	1.15	1.17
PYRIDINE-2,3-DICARBOXYLATE	ME645269	0.74	0.61	1.13	1.21
PYRIDOXINE	ME645271	0.73	0.67	1.11	1.19
STACHYOSE	ME645281	0.73	0.75	1.16	1.29
N-ACETYL-L-PHENYLALANINE	ME645239	0.83	0.78	1.17	1.29
OCTADECANEDIOATE	ME645248	0.83	0.70	1.22	1.30
3-(2-HYDROXYPHENYL)PROPANOATE	ME645080	0.85	0.65	1.34	1.24
4-(2-AMINO-3-HYDROXYPHENYL)-2,4-DIOXOBUTANOATE	ME645101	0.86	0.58	1.12	1.21
N-ACETYL-D-GALACTOSAMINE	ME645235	0.94	0.56	1.13	1.28
BOC-MET-OH	ME645148	0.90	0.58	1.13	1.52
HIPPURATE	ME645209	0.90	0.55	1.22	1.54
DIMETHYLXANTHINE	ME645176	0.89	0.52	1.22	1.54
N-CYCLOHEXYLSULFAMIC ACID	ME645242	0.89	0.53	1.21	1.53
2-OXOBUTANOATE	ME645079	0.71	0.59	1.14	1.39
METHIONINE	ME645230	0.73	0.61	1.25	1.51
4-PYRIDOXATE	ME645111	1.16	0.68	1.06	1.35
DESMETHYLNAPROXEN SULFATE	ME645170	1.17	0.46	1.08	1.24
PHTHALATE	ME645264	0.42	1.02	1.23	1.15
1-HYDROXY-2-NAPHTHOATE	ME645070	0.61	1.29	0.81	1.57
13(S)-HPODE	ME645067	0.53	1.29	0.94	1.19
CINNAMIC ACID	ME645159	0.52	0.99	1.01	1.41
FUMARIC ACID	ME645187	0.69	0.99	1.03	1.29
MALATE	ME645226	0.65	0.96	1.04	1.35
4-HYDROXY-3-METHOXY-BENZENEMETHANOL	ME645106	0.73	1.05	0.84	1.38
LAURIC ACID	ME645222	0.89	1.10	0.84	1.32
3-HYDROXYBENZYL ALCOHOL	ME645092	0.88	1.10	0.86	1.17
HYDROXYDECANOATE	ME645212	0.81	1.17	0.83	1.21
GLYOXAL	ME645199	0.15	1.42	0.93	0.84
HEXACOSANOIC ACID	ME645204	0.42	1.56	0.92	0.86
OXALOSUCCINATE	ME645253	0.77	1.54	0.91	0.58
GLYCERIC ACID	ME645194	0.57	1.40	0.64	0.99
LIGNOCERIC ACID	ME645223	0.59	1.52	0.73	0.82
2-HYDROXYSTEARATE	ME645076	0.84	1.52	0.62	0.98
ARACHIDIC ACID	ME645134	0.93	1.54	0.78	0.86
DODECENOATE	ME645180	0.91	1.53	0.68	0.75
CHENODEOXYCHOLATE	ME645155	0.91	1.49	0.67	0.83
URSODIOL	ME645300	0.89	1.51	0.66	0.84
ADENINE	ME645125	0.90	1.51	0.90	0.98
XANTHOSINE 5^-MONOPHOSPHATE	ME645302	0.76	1.45	0.99	0.81
DIHOMO-LINOLEATE	ME645173	1.56	0.99	0.80	0.67
DIHOMO-LINOLENATE	ME645174	1.53	1.16	0.62	0.76
OLEATE	ME645249	1.48	1.08	0.67	0.77
URIDINE	ME645298	1.36	1.55	0.59	0.64
3-HYDROXY-DL-KYNURENINE	ME645093	1.14	1.22	0.53	0.59
LINOLEATE	ME645224	1.34	1.23	0.74	0.71
3ALPHA,7ALPHA,12ALPHA-TRIHYDROXY-5BETA-CHOLESTANOATE	ME645085	1.25	1.29	0.55	0.84
NONADECANOATE / METHYLSTEARATE (*)	ME645246	1.21	1.31	0.69	0.76
GERANYL PYROPHOSPHATE	ME645190	1.06	0.88	1.23	0.58
TAUROCHOLATE	ME645286	1.08	1.27	1.01	0.50
3-METHOXY-L-TYROSINE	ME645094	0.97	NA	1.51	0.76
3-HYDROXYANTHRANILATE	ME645090	0.91	NA	1.05	0.99
4-HYDROXY-3-METHOXYPHENYLGLYCOL	ME645107	1.07	NA	0.82	1.02
INOSINE 5`-TRIPHOSPHATE	ME645219	1.18	NA	0.99	0.93
SALICYLURIC GLUCURONIDE	ME645276	1.08	NA	0.98	0.97
2-CARBOXY-2,3-DIHYDRO-5,6-DIHYDROXYINDOLE	ME645073	1.05	0.23	0.85	1.51
DEHYDROISOANDROSTERONE 3-SULFATE	ME645168	0.57	0.42	0.84	1.45
3-(4-HYDROXYPHENYL)LACTATE	ME645081	0.72	0.30	1.38	1.22
CARNOSINE	ME645153	0.63	0.29	1.49	1.22
3-HYDROXY-3-METHYLGLUTARATE	ME645089	0.74	0.49	1.38	1.53
PANTOATE	ME645258	0.55	0.36	1.32	1.48
B-ALANYL-N(PAI)-METHYL-L-HISTIDINE	ME645141	0.62	0.42	1.55	1.40
METHYL BETA-D-GALACTOSIDE	ME645231	0.38	0.38	1.50	1.45
HYDROXYACETAMINOPHEN SULFATE	ME645210	0.59	0.80	1.49	1.77
4-ANDROSTEN-3BETA,17BETA-DIOL DISULFATE	ME645104	0.76	0.39	1.17	1.92
3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPANOATE	ME645088	0.59	0.28	1.35	1.82
CATECHOL	ME645154	0.52	0.40	1.33	1.98
MYRISTIC ACID	ME645232	0.80	NA	NA	1.40
PROGESTERONE	ME645266	1.16	NA	NA	0.84
PHOSPHOCREATINE	ME645263	0.85	0.90	NA	1.25
ROSMARINIC ACID	ME645274	0.48	0.57	0.35	1.32
GUANIDINOACETATE	ME645201	0.92	1.31	NA	0.77
RIBOFLAVIN	ME645273	1.25	0.82	NA	0.61
PHENYLPYRUVATE	ME645261	NA	NA	0.73	1.54
6-HYDROXYNICOTINATE	ME645119	NA	NA	0.97	1.03
BENZOATE	ME645143	NA	NA	0.98	1.12
1-AMINOCYCLOPROPANE-1-CARBOXYLATE	ME645069	NA	NA	0.83	1.12
3-SULFINO-L-ALANINE	ME645100	NA	NA	0.74	1.09
S-CARBOXYMETHYL-L-CYSTEINE	ME645277	0.40	NA	1.60	NA
3,4-DIHYDROXYPHENYL GLYCOL	ME645083	NA	0.71	1.10	NA
SALICYLIC ACID	ME645275	0.34	0.58	1.54	NA
11BETA,21-DIHYDROXY-5BETA-PREGNANE-3,20-DIONE	ME645065	NA	0.45	1.55	NA
BILIVERDIN	ME645144	NA	0.54	1.46	NA
N-BENZYLOXYCARBONYLGLYCINE	ME645241	NA	0.77	1.30	0.98
N-FORMYLGLYCINE	ME645243	NA	0.71	1.22	0.93
2,3-DIPHOSPHO-D-GLYCERIC ACID	ME645071	NA	0.95	1.20	0.70
5-AMINOLEVULINIC ACID	ME645114	NA	0.98	1.09	0.86
HEXITOL	ME645207	NA	1.19	1.02	0.39
MELATONIN	ME645228	NA	1.42	0.86	NA
PYRIDOXAL	ME645270	NA	1.23	0.77	NA
PREGN STEROID MONOSULFATE	ME645265	1.74	2.25	0.52	0.21
CHOLATE	ME645156	1.82	1.40	0.35	0.37
DOCOSAPENTAENOATE	ME645178	2.11	1.27	0.63	0.58
XANTHINE	ME645301	0.63	1.37	NA	NA
ALDOSTERONE	ME645126	0.88	2.14	0.37	0.73
ANDROSTERONE GLUCURONIDE	ME645132	0.41	2.15	0.96	0.52

Factors:

F1	Feeeding:Ad lib \| Running Capacity:High
F2	Feeeding:Ad lib \| Running Capacity:Low
F3	Feeeding:Calorie restricted \| Running Capacity:High
F4	Feeeding:Calorie restricted \| Running Capacity:Low

Data matrix