Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Metabolite changes associated with methionine stress sensitivity of cancer (GC TOF MS analysis) (Study ST000058)

MS positive ion mode (Analysis AN000096)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7
maltose	ME652234	1.19	0.51	3.01	0.50	0.69	0.57	0.53
ononitol	ME652244	0.57	1.27	0.60	2.68	0.71	0.46	0.71
urea	ME652278	0.67	2.35	0.76	0.97	0.63	0.45	1.16
putrescine	ME652255	0.80	0.74	0.97	0.90	0.69	0.65	2.24
fructose-6-phosphate	ME652191	1.11	0.49	0.64	0.60	0.77	1.15	2.24
sorbitol	ME652263	1.17	0.34	0.52	0.87	0.71	1.58	1.81
cellobiotol	ME652173	1.09	0.88	1.88	0.64	0.59	0.75	1.17
aspartic acid	ME652167	0.80	0.63	1.27	2.03	1.15	0.58	0.54
cysteine	ME652179	1.17	0.89	1.24	1.82	0.87	0.72	0.29
uridine	ME652279	1.26	2.22	1.25	0.94	0.57	0.49	0.26
guanosine	ME652211	1.10	1.93	1.34	1.12	0.66	0.58	0.27
inosine	ME652219	1.13	1.87	1.16	1.15	0.68	0.67	0.35
uridine-5^-monophosphate	ME652280	1.20	0.91	1.31	1.04	0.99	1.23	0.32
GABA	ME652193	1.44	1.13	1.02	0.74	0.67	1.04	0.96
galacturonic acid	ME652196	1.47	1.26	0.94	0.90	0.64	0.82	0.97
beta alanine	ME652170	1.58	1.18	1.18	0.79	0.67	0.96	0.64
thymine	ME652272	1.46	1.01	1.13	0.76	0.97	1.00	0.67
sucrose	ME652268	0.95	1.28	1.35	0.87	0.72	1.01	0.82
UDP-glucuronic acid	ME652276	0.95	1.51	1.49	0.85	0.60	1.02	0.59
guanine	ME652210	1.02	1.48	1.21	1.16	0.85	0.90	0.39
hypoxanthine	ME652217	1.20	1.32	1.09	1.18	0.80	0.90	0.52
succinic acid	ME652267	1.44	1.23	1.27	1.20	0.82	0.59	0.44
2-hydroxyglutaric acid	ME652146	1.52	1.58	1.05	0.98	0.66	0.78	0.43
uracil	ME652277	1.28	1.46	1.19	1.17	0.73	0.69	0.48
adenosine	ME652157	1.44	1.46	1.13	1.01	0.72	0.66	0.58
cytidine-5^-diphosphate	ME652181	1.33	1.47	1.20	1.00	0.78	0.69	0.54
1-monoolein	ME652143	0.67	0.71	0.86	0.96	1.15	0.95	1.70
2-monoolein	ME652148	0.66	0.68	0.74	1.01	1.15	1.01	1.75
2-monopalmitin	ME652149	0.62	0.61	0.68	1.10	1.49	1.08	1.41
monopalmitin-1-glyceride	ME652238	0.67	0.71	0.77	1.03	1.32	1.11	1.39
asparagine	ME652164	0.82	0.64	0.97	1.19	0.95	1.65	0.78
histidine	ME652213	0.88	0.48	0.93	1.48	0.65	1.57	1.03
glucose-6-phosphate	ME652201	0.81	0.83	0.77	0.98	0.80	1.58	1.23
aminomalonic acid	ME652162	1.12	0.67	1.04	0.93	0.66	1.44	1.13
glycine	ME652208	1.04	0.76	0.91	0.98	0.74	1.44	1.13
lysine	ME652231	1.07	0.73	1.04	0.92	0.83	1.24	1.16
pyrophosphate	ME652257	1.10	0.64	0.96	0.91	1.01	1.30	1.08
glycerol-alpha-phosphate	ME652206	0.69	0.50	0.65	1.00	0.96	1.50	1.69
leucine	ME652229	0.58	0.58	1.18	1.15	1.03	1.19	1.29
glycerol-beta-phosphate	ME652207	0.84	0.62	0.83	1.06	0.92	1.35	1.37
isoleucine	ME652224	0.75	0.59	0.86	1.18	0.92	1.30	1.40
tyrosine	ME652274	0.76	0.60	0.80	1.14	0.86	1.43	1.42
phenylalanine	ME652252	0.77	0.61	0.83	1.18	0.85	1.42	1.34
tryptophan	ME652273	0.76	0.62	0.83	1.21	0.85	1.36	1.37
alanine	ME652160	0.96	0.42	0.88	1.16	1.02	1.23	1.33
valine	ME652281	0.79	0.55	0.99	1.23	0.97	1.18	1.29
fructose 1 phosphate	ME652189	1.38	0.67	0.62	1.33	1.25	1.09	0.65
levoglucosan	ME652230	0.90	0.88	0.92	1.42	1.23	0.81	0.84
glucose-1-phosphate	ME652200	0.77	0.96	0.79	1.75	1.19	0.80	0.74
glyceric acid	ME652204	0.83	0.86	0.90	1.67	1.00	0.90	0.84
galactose-6-phosphate_200536	ME652195	0.90	1.20	1.09	1.12	1.15	0.64	0.89
7-alpha-hydroxycholesterol	ME652154	1.13	1.04	1.20	1.07	1.21	0.61	0.74
aspartate	ME652166	1.22	1.13	1.29	1.03	1.01	0.59	0.73
N-acetyl-D-mannosamine	ME652241	0.94	0.86	1.20	0.89	1.41	0.86	0.84
hydroxycarbamate NIST	ME652215	0.83	1.04	1.29	0.93	1.04	1.01	0.85
2-deoxyerythritol	ME652145	1.00	1.02	1.19	0.98	1.08	0.93	0.79
5b-cholestanol	ME652152	1.01	1.18	1.06	0.97	1.11	0.94	0.73
2-aminoadipic acid	ME652144	1.28	1.12	0.89	1.04	1.06	0.79	0.81
inosine 5^-monophosphate	ME652220	1.44	1.15	1.00	1.05	1.04	0.56	0.77
conduritol beta epoxide	ME652177	1.23	1.04	1.12	1.21	0.77	0.73	0.90
inositol myo-	ME652221	1.26	1.04	1.23	1.19	0.66	0.74	0.87
taurine	ME652269	1.43	1.13	1.13	1.15	0.83	0.77	0.56
glycerol-3-galactoside	ME652205	1.33	1.10	1.09	1.11	0.76	0.82	0.79
methionine	ME652237	1.46	1.01	1.09	1.10	0.84	0.73	0.78
pyrazine 2,5-dihydroxy NIST	ME652256	1.21	0.83	1.14	1.60	0.90	0.78	0.55
pyruvic acid	ME652258	1.27	0.85	0.99	1.40	1.12	0.78	0.59
fumarate	ME652192	1.31	0.91	1.06	1.34	1.00	0.77	0.61
malate	ME652232	1.25	0.94	1.10	1.30	1.03	0.76	0.62
pantothenic acid	ME652249	1.05	1.14	0.90	1.18	1.01	1.04	0.67
glutamine	ME652203	0.87	1.05	1.25	1.34	0.86	1.03	0.61
aconitic acid	ME652155	1.09	1.02	1.02	1.41	0.71	0.94	0.80
glucose	ME652199	1.08	1.03	1.02	1.40	0.96	0.90	0.62
oxoproline	ME652246	1.02	0.88	1.11	1.39	0.90	1.05	0.65
fructose-1,6-bisphosphate	ME652190	0.94	1.01	0.76	0.80	1.20	1.33	0.95
gamma glutamyl-valine	ME652197	0.93	1.11	0.95	0.80	1.01	1.32	0.88
3-phosphoglycerate	ME652150	0.83	0.88	0.85	1.07	1.42	0.98	0.97
fructose	ME652188	1.15	0.98	0.77	0.87	1.21	1.00	1.02
N-acetylgalactosamine	ME652242	1.11	1.00	0.79	0.91	1.42	0.87	0.90
glucoheptulose	ME652198	0.68	1.23	0.85	1.04	0.92	0.91	1.37
methanolphosphate	ME652236	0.93	0.84	1.02	0.90	1.02	0.81	1.48
ethanolamine	ME652187	0.89	0.88	1.01	0.99	0.90	0.97	1.35
idonic acid NIST	ME652218	0.97	0.97	1.02	0.90	1.01	0.87	1.27
stigmasterol	ME652266	0.95	1.02	0.68	0.87	0.96	1.15	1.36
2-ketoisocaproic acid	ME652147	0.94	0.82	0.97	0.89	0.96	1.14	1.29
elaidic acid	ME652184	0.84	0.91	0.84	0.95	1.04	1.05	1.37
myristic acid	ME652239	0.97	0.83	0.77	0.94	1.14	1.08	1.27
cytosin	ME652183	1.16	0.80	1.01	1.16	0.78	1.21	0.88
glutamic acid	ME652202	1.31	0.74	0.95	1.23	0.76	1.23	0.78
citric acid	ME652175	1.33	0.99	0.97	1.07	0.72	1.08	0.84
isocitric acid	ME652223	1.30	0.95	0.93	1.17	0.84	1.00	0.81
N-acetylaspartic acid	ME652240	1.41	0.78	0.99	1.04	0.75	1.09	0.95
isothreonic acid	ME652225	1.40	0.89	0.97	0.96	0.65	1.22	0.91
pelargonic acid	ME652250	1.46	0.90	0.89	0.89	0.72	1.11	1.03
lactamide	ME652226	1.23	0.79	0.89	1.07	1.04	1.12	0.86
lactic acid	ME652227	1.30	0.71	0.74	1.13	0.99	1.22	0.91
lauric acid	ME652228	1.10	0.79	0.77	1.25	1.02	0.98	1.09
adenosine-5-phosphate	ME652158	1.01	0.77	0.96	1.13	1.01	1.11	1.01
thymidine-5-monophosphate	ME652271	1.02	0.86	0.92	1.14	1.01	1.11	0.95
pentadecanoic acid	ME652251	1.18	0.96	0.87	1.04	0.98	0.85	1.12
inositol-4-monophosphate	ME652222	1.28	1.00	1.00	1.01	0.80	0.89	1.01
palmitoleic acid	ME652248	1.32	1.02	0.97	1.06	0.82	0.79	1.02
behenic acid	ME652168	0.98	1.08	1.11	1.17	0.95	0.94	0.77
hydroxylamine	ME652216	0.93	1.06	0.99	1.16	0.85	1.07	0.94
cholesterol	ME652174	0.98	1.00	0.98	1.28	0.98	0.88	0.90
ribulose-5-phosphate	ME652260	0.90	1.11	0.97	1.21	0.92	0.88	0.99
1-hexadecanol	ME652142	0.97	1.17	1.01	0.99	0.92	0.84	1.09
benzoic acid	ME652169	0.98	0.98	1.06	1.01	0.98	0.99	0.99
glycolic acid	ME652209	1.04	0.96	0.99	1.11	0.96	0.87	1.07
adipic acid	ME652159	1.05	1.15	0.97	0.99	0.95	0.98	0.91
arachidic acid	ME652163	1.11	1.07	1.01	0.96	0.85	1.03	0.97
maleimide	ME652233	1.12	1.06	0.93	1.12	0.96	0.92	0.89
heptadecanoic acid	ME652212	1.11	0.93	0.87	1.01	1.02	1.05	1.01
palmitic acid	ME652247	1.10	0.99	0.91	1.02	0.98	1.05	0.96
stearic acid	ME652265	1.17	0.99	0.92	1.03	0.96	1.02	0.91
butane-2,3-diol	ME652171	1.07	0.91	1.05	0.87	1.13	0.98	0.99
CMP	ME652176	1.02	0.79	1.07	0.97	1.01	0.97	1.17
galactinol isomer	ME652194	1.16	0.90	0.87	0.81	0.99	1.20	1.07
creatinine	ME652178	1.13	0.89	1.08	1.07	0.92	1.06	0.85
spermidine	ME652264	1.15	0.90	1.06	0.87	0.94	1.22	0.86
oxalic acid	ME652245	0.81	0.90	1.20	1.10	1.05	0.83	1.10
capric acid	ME652172	0.75	0.94	0.91	1.18	1.13	0.94	1.16
enolpyruvate NIST	ME652185	0.73	0.91	1.00	1.26	1.16	0.72	1.22
proline	ME652254	0.88	0.74	1.16	1.30	0.94	1.15	0.83
nicotinamide	ME652243	0.67	0.81	1.04	1.24	1.03	1.10	1.10
threonine	ME652270	0.77	0.74	1.01	1.29	0.96	1.20	1.02
salicylic acid	ME652261	0.97	0.82	1.10	1.25	1.00	0.87	0.98
cytidine-5-monophosphate	ME652182	0.86	0.84	0.96	1.37	1.01	0.94	1.01
serine	ME652262	0.87	0.73	0.99	1.30	1.01	1.05	1.05
UDP GlcNAc	ME652275	0.75	0.58	0.93	1.33	1.09	1.36	0.96
5-aminovaleric acid	ME652151	0.74	0.84	0.88	1.23	0.81	1.29	1.22
erythritol	ME652186	0.81	0.90	0.87	1.27	0.94	1.28	0.93
xylulose NIST	ME652282	0.90	0.82	0.86	1.17	1.00	1.31	0.94
asparagine dehydrated	ME652165	0.61	0.46	0.97	1.91	0.94	1.28	0.84
phenylethylamine	ME652253	0.26	1.04	1.17	1.35	0.79	1.26	1.13
adenine	ME652156	1.97	0.38	0.50	0.69	0.72	1.42	1.33
5^-deoxy-5^-methylthioadenosine	ME652153	2.04	0.53	0.57	0.73	0.65	1.17	1.30
homoserine	ME652214	2.04	0.56	0.52	0.81	0.62	1.20	1.24
alpha ketoglutaric acid	ME652161	1.47	0.87	0.68	0.75	0.65	1.60	0.97
ribitol	ME652259	1.72	0.81	0.71	0.82	0.43	1.34	1.16
cysteine-glycine	ME652180	1.88	0.70	1.17	1.55	0.68	0.73	0.28
maltotriose minor	ME652235	2.00	1.02	0.80	0.82	0.93	0.64	0.78

Factors:

F1	Treatment:Group 1: Methionine Treated - Group 1
F2	Treatment:Group 2: Homocysteine Treated-2 hours - Group 2
F3	Treatment:Group 3: Homocysteine Treated- 4 hours - Group 3
F4	Treatment:Group 4: Homocysteine Treated- 8 hours - Group 4
F5	Treatment:Group 5: Homocysteine Treated- 12 hours - Group 5
F6	Treatment:Group 6: Homocysteine Treated- 24 hours - Group 6
F7	Treatment:Group 7: Homocysteine Treated- 48 hours - Group 7

Data matrix