Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Noxa regulation of malate aspartate shuttle (Study ST000146)

ESI/QTOF negative ion mode (Analysis AN000232)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
Citrate or Isocitrate_13C_3	ME685440	1.23	0.70	0.41	2.10	0.77	1.03
Nicotinamide Adenine Dinucleotide oxidized_13C_3	ME685490	0.51	NA	0.92	2.10	1.12	1.26
Aspartate	ME685426	0.29	1.65	1.00	1.10	0.28	1.68
Malate_13C_4	ME685483	0.84	1.29	0.39	1.06	NA	0.93
3-Glycerophosphate_13C_2	ME685468	1.39	0.00	0.27	0.00	3.01	0.00
Sedoheptulose 7-phosphate	ME685507	0.73	NA	0.25	0.08	2.64	NA
Adenosine diphosphate	ME685414	1.41	0.04	1.14	0.02	2.72	0.03
Glucose 6-phosphate or fructose-6-phosphate_13C_1	ME685460	1.22	0.04	1.56	0.06	3.06	0.05
Nicotinamide Adenine Dinucleotide oxidized	ME685396	0.94	0.03	1.44	0.08	3.17	0.04
Ribose-5-phosphate or xylulose 5-phosphate	ME685501	0.74	0.07	0.46	0.83	3.43	0.10
Glucose 6-phosphate or fructose-6-phosphate	ME685459	0.99	0.04	1.09	0.20	3.63	0.05
3-Glycerophosphate	ME685466	1.02	0.01	0.78	0.01	4.18	0.01
Fructose 1,6-bisphosphate_13C_1	ME685449	1.52	0.12	0.57	0.06	3.65	0.08
3-Glycerophosphate_13C_1	ME685467	1.35	0.00	0.65	0.00	3.99	0.00
Fructose 1,6-bisphosphate	ME685394	1.27	0.13	0.55	0.06	3.89	0.10
Glutamate_13C_3	ME685473	1.52	NA	0.34	NA	1.07	NA
Adenosine triphosphate_13C_3	ME685434	1.08	NA	1.20	NA	0.78	NA
Glutamate_13C_1	ME685471	1.65	0.56	0.97	0.35	0.74	NA
Malate_13C_3	ME685482	1.68	NA	0.79	NA	0.30	NA
Sedoheptulose 7-phosphate_13C_5	ME685512	0.07	NA	0.06	NA	1.93	NA
Sedoheptulose 7-phosphate_13C_6	ME685513	NA	0.22	NA	NA	1.68	0.37
Adenosine diphosphate_13C_2	ME685416	0.87	NA	0.02	NA	1.37	NA
Nicotinamide Adenine Dinucleotide reduced_13C_4	ME685496	0.68	NA	0.15	NA	1.50	NA
Nicotinamide Adenine Dinucleotide reduced	ME685397	0.52	NA	0.39	NA	2.09	NA
Sedoheptulose 7-phosphate_13C_1	ME685508	0.53	NA	0.22	NA	2.25	NA
Ribose-5-phosphate or xylulose 5-phosphate_13C_1	ME685502	0.75	NA	0.31	0.17	1.91	NA
Nicotinamide Adenine Dinucleotide reduced_13C_1	ME685493	0.61	NA	0.45	NA	1.94	NA
Nicotinamide Adenine Dinucleotide reduced_13C_2	ME685494	0.68	NA	0.47	NA	1.85	NA
Nicotinamide Adenine Dinucleotide reduced_13C_3	ME685495	0.73	NA	0.49	NA	1.78	NA
Adenosine diphosphate_13C_1	ME685415	1.15	0.01	0.91	NA	1.60	0.01
3-phosphoglyceraldehyde	ME685455	0.78	NA	0.70	NA	1.52	NA
3-phosphoglyceraldehyde_13C_1	ME685456	0.83	NA	0.53	NA	1.64	NA
Fructose 1,6-bisphosphate_13C_2	ME685450	1.03	0.13	0.51	NA	1.75	NA
Ribose-5-phosphate or xylulose 5-phosphate_13C_2	ME685503	1.07	NA	0.33	NA	1.62	NA
2 or 3-phosphoglycerate_2PG/3PG	ME685400	0.80	0.09	1.44	0.18	1.65	0.06
Adenosine monophosphate	ME685420	1.05	0.04	1.37	0.07	2.14	NA
6-Phosphogluconate_13C_1	ME685405	0.36	NA	1.52	NA	1.13	NA
Malonyl-CoA	ME685484	0.37	NA	1.22	NA	1.41	NA
Malonyl-CoA_13C_1	ME685485	0.32	NA	1.25	NA	1.43	NA
Adenosine triphosphate_13C_2	ME685433	0.99	NA	0.91	NA	1.10	NA
Lactate	ME685476	0.68	NA	1.19	NA	1.14	NA
Acetyl-CoA_13C_1	ME685412	0.73	NA	1.02	NA	1.25	NA
Adenosine monophosphate_13C_1	ME685421	0.85	NA	1.15	0.01	1.33	NA
Acetyl-CoA	ME685411	0.62	NA	0.95	NA	1.43	NA
Nicotinamide Adenine Dinucleotide oxidized_13C_1	ME685488	0.56	NA	0.90	NA	1.55	NA
6-Phosphogluconate	ME685404	0.66	0.15	1.02	NA	1.60	NA
Nicotinamide Adenine Dinucleotide oxidized_13C_2	ME685489	0.70	NA	1.12	NA	1.51	0.00
Erythrose 4-phosphate	ME685444	0.49	0.02	0.90	NA	1.94	NA
Lactate_13C_1	ME685477	0.44	NA	0.89	NA	1.68	NA
Citrate or Isocitrate_13C_1	ME685438	2.48	0.24	1.82	0.59	0.27	0.60
Glutamate_13C_2	ME685472	2.43	0.08	1.83	0.57	NA	0.10
Malate	ME685395	2.13	0.05	2.50	0.12	1.14	0.07
Malate_13C_1	ME685480	2.71	0.03	2.62	0.06	0.53	0.05
Malate_13C_2	ME685481	2.83	0.09	2.42	0.07	0.26	0.03
Adenosine triphosphate	ME685431	1.95	0.04	1.64	0.03	2.30	0.04
Adenosine triphosphate_13C_1	ME685432	2.01	0.03	1.82	0.03	1.75	0.04
Glutamate	ME685470	1.67	0.23	2.01	0.31	1.49	0.29
Sucrose	ME685399	1.06	0.40	2.22	0.38	1.35	0.60
Citrate or Isocitrate	ME685437	1.83	0.37	1.61	0.59	0.82	0.79
Citrate or Isocitrate_13C_6	ME685443	1.11	0.84	1.69	0.84	0.85	0.94
Aspartate_13C_1	ME685427	1.06	0.12	3.52	0.14	0.20	0.04
Aspartate_13C_2	ME685428	NA	1.24	2.23	0.84	NA	0.23
Citrate or Isocitrate_13C_2	ME685439	0.80	1.02	2.37	0.68	0.08	0.38
Glucose 6-phosphate or fructose-6-phosphate_13C_6	ME685465	0.59	0.87	1.73	NA	0.81	NA
Sucrose_13C_1	ME685515	0.15	NA	2.17	0.21	0.77	NA

Factors:

F1	genotype:Noxa knockdown line
F2	genotype:Noxa knockdown line medium
F3	genotype:Noxa overexpressing line
F4	genotype:Noxa overexpressing line medium
F5	genotype:Parental line
F6	genotype:Parental line medium

Data matrix