Clustering data with hclust algorithm for Metabolomic effects of metformin on mouse liver, intestine, and serum (Study ST000325)
HILIC POSITIVE ION MODE (Analysis AN000518)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 |
|---|---|---|---|---|---|---|---|---|---|---|
| 1-Methylhistidine | ME115005 | 0.04 | 0.04 | 0.04 | 0.12 | 0.10 | 0.09 | 2.67 | 3.47 | 2.13 |
| Acylcarnitine (C4:0) | ME115008 | 0.31 | 0.34 | 0.40 | 0.22 | 0.17 | 0.17 | 2.07 | 2.65 | 2.54 |
| Acylcarnitine (C6:0) | ME115010 | 0.34 | 0.24 | 0.14 | 0.25 | 0.20 | 0.17 | 1.75 | 2.11 | 2.49 |
| Acylcarnitine (C5:0) | ME115009 | 0.39 | 0.51 | 0.45 | 0.81 | 0.59 | 0.58 | 1.64 | 1.96 | 1.99 |
| Isoleucine | ME115013 | 0.94 | 0.49 | 0.42 | 0.37 | 0.40 | 0.48 | 1.94 | 2.07 | 1.80 |
| Acylcarnitine (C2:0) | ME115006 | 2.57 | 2.46 | 1.99 | 0.39 | 0.36 | 0.22 | 0.33 | 0.29 | 0.26 |
| Hypoxanthine | ME115012 | 1.82 | 1.93 | 2.06 | 0.81 | 1.01 | 1.14 | 0.01 | 0.05 | 0.03 |
| PE(36:2) | ME115025 | 1.92 | 1.77 | 1.76 | 1.00 | 1.00 | 0.93 | 0.21 | 0.20 | 0.20 |
| PC(32:0) | ME115015 | 1.46 | 1.62 | 1.60 | 0.85 | 0.88 | 1.00 | 0.48 | 0.57 | 0.55 |
| PE(38:6) | ME115028 | 1.74 | 1.92 | 1.88 | 0.61 | 0.68 | 0.69 | 0.47 | 0.46 | 0.49 |
| Choline | ME115011 | 1.18 | 1.22 | 1.25 | 0.83 | 1.00 | 0.84 | 0.82 | 0.94 | 0.89 |
| PC(34:2) | ME115018 | 0.91 | 0.88 | 0.95 | 0.96 | 1.02 | 1.01 | 1.10 | 1.05 | 1.09 |
| PC(34:3) | ME115019 | 0.57 | 0.56 | 0.55 | 1.37 | 1.56 | 1.55 | 1.00 | 0.95 | 0.99 |
| PC(32:2) | ME115017 | 0.78 | 0.61 | 0.67 | 1.46 | 1.60 | 1.62 | 0.84 | 0.75 | 0.77 |
| TG(52:3) | ME115031 | 0.48 | 0.81 | 0.62 | 1.53 | 1.50 | 1.81 | 0.82 | 0.77 | 0.79 |
| PC(38:4) | ME115021 | 0.84 | 1.15 | 0.86 | 1.17 | 1.21 | 1.93 | 0.77 | 0.61 | 0.61 |
| PC(36:4) | ME115020 | 0.97 | 1.06 | 1.11 | 1.41 | 1.47 | 0.99 | 0.88 | 0.56 | 0.73 |
| PC(32:1) | ME115016 | 1.09 | 1.10 | 1.10 | 1.23 | 1.25 | 1.36 | 0.69 | 0.61 | 0.66 |
| TG(50:2) | ME115029 | 0.91 | 1.36 | 1.22 | 1.23 | 1.24 | 1.34 | 0.66 | 0.56 | 0.53 |
| Lidocaine | ME115014 | 0.69 | 1.00 | 1.00 | 1.45 | 1.50 | 1.48 | 0.72 | 0.60 | 0.64 |
| TG(54:4) | ME115032 | 0.70 | 1.28 | 0.84 | 1.44 | 1.39 | 1.33 | 0.77 | 0.66 | 0.64 |
| PC(40:6) | ME115023 | 0.29 | 0.45 | 0.29 | 1.45 | 1.85 | 3.08 | 0.68 | 0.61 | 0.63 |
| PC(38:6) | ME115022 | 0.28 | 0.39 | 0.31 | 1.93 | 2.26 | 1.68 | 0.94 | 0.54 | 0.78 |
| TG(50:6) | ME115030 | 0.11 | 0.13 | 0.17 | 1.92 | 2.24 | 2.15 | 0.86 | 0.75 | 0.73 |
| Acylcarnitine (C3:0) | ME115007 | 0.31 | 0.36 | 0.33 | 3.05 | 2.64 | 2.07 | 0.13 | 0.14 | 0.14 |
| PE(34:2) | ME115024 | 0.97 | 0.82 | 0.87 | 2.14 | 2.14 | 1.86 | 0.13 | 0.11 | 0.10 |
| PE(36:3) | ME115026 | 0.58 | 1.12 | 0.99 | 1.79 | 2.04 | 2.25 | 0.16 | 0.13 | 0.15 |
| PE(38:4) | ME115027 | 0.48 | 0.96 | 1.31 | 1.95 | 1.79 | 2.41 | 0.12 | 0.10 | 0.12 |
Factors:
| F1 | Organ:intestine | Treatment:Metformin 150 mg |
| F2 | Organ:intestine | Treatment:Metformin 50 mg |
| F3 | Organ:intestine | Treatment:Saline |
| F4 | Organ:liver | Treatment:Metformin 150 mg |
| F5 | Organ:liver | Treatment:Metformin 50 mg |
| F6 | Organ:liver | Treatment:Saline |
| F7 | Organ:serum | Treatment:Metformin 150 mg |
| F8 | Organ:serum | Treatment:Metformin 50 mg |
| F9 | Organ:serum | Treatment:Saline |
