Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Temporal metabolomic responses of cultured HepG2 liver cells to high fructose and high glucose exposures (part II) (Study ST000380)

HILIC POSITIVE ION MODE (Analysis AN000614)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13
Acylcarnitine C16:1	ME132847	0.69	0.51	0.46	0.69	0.98	0.97	1.26	1.09	1.88	1.40	2.16	0.75	0.36
Acylcarnitine C14:0	ME132846	0.59	0.42	0.59	0.57	1.10	0.87	1.76	0.93	1.61	1.10	2.81	0.66	0.27
Acylcarnitine C16:0	ME132848	0.84	0.54	0.58	0.60	1.19	0.85	1.53	0.84	1.58	1.05	2.53	0.62	0.48
Acylcarnitine C18:1	ME132849	0.77	0.51	0.64	0.61	0.99	0.81	1.45	0.92	1.76	1.21	2.55	0.61	0.41
Acylcarnitine C14:1	ME132845	0.42	0.29	0.58	0.37	0.94	0.90	1.95	0.82	1.50	1.13	3.77	0.59	0.18
Acylcarnitine C12:0	ME132844	0.52	0.30	0.71	0.41	1.08	0.87	2.49	0.93	1.26	0.84	3.28	0.58	0.10
Acylcarnitine C18:0	ME132850	0.60	0.36	0.87	0.49	0.92	0.55	2.29	0.67	1.35	0.81	3.69	0.50	0.31
Acylcarnitine C4:0	ME132839	0.83	1.23	0.58	1.02	0.88	2.09	0.68	0.97	0.89	1.84	0.32	1.15	0.41
Glutamine	ME132833	1.05	1.41	0.27	1.36	0.82	1.80	0.23	1.14	0.95	1.57	0.11	1.39	0.76
Pantothenic Acid	ME132838	0.92	1.33	0.44	1.35	0.81	1.45	0.49	1.34	0.84	1.47	0.29	1.56	0.64
5^-Methylthioadenosine	ME132843	1.06	0.97	1.69	0.52	0.98	0.80	1.44	0.54	1.16	1.05	1.76	0.52	0.55
Adenine	ME132832	1.05	0.98	1.58	0.56	0.98	0.82	1.41	0.53	1.21	1.12	1.59	0.57	0.61
Choline	ME132826	1.14	1.00	1.53	1.06	0.92	1.05	1.31	0.98	0.62	0.54	0.52	0.81	1.43
Creatine	ME132831	0.92	0.77	0.90	1.03	1.07	1.15	1.29	1.11	0.89	0.85	1.50	1.08	0.55
Taurine	ME132830	0.91	0.87	0.91	0.94	1.06	1.13	1.29	0.84	1.29	1.23	1.42	0.88	0.26
Taurine Dimer	ME132840	0.84	0.76	0.82	0.84	1.03	1.16	1.47	0.77	1.49	1.34	1.66	0.79	0.11
Carnitine	ME132834	0.79	0.98	1.05	1.00	0.92	1.45	1.12	0.91	1.07	1.38	0.64	1.24	0.38
Creatinine	ME132827	1.04	0.94	0.92	1.07	0.91	1.10	0.87	1.17	1.04	1.37	0.67	1.49	0.39
Adenosine	ME132842	1.07	0.79	1.06	1.23	1.09	1.26	1.35	1.35	0.75	0.66	0.88	0.87	0.70
Proline	ME132828	0.87	0.91	1.36	1.21	0.82	0.97	1.30	1.09	0.79	0.94	0.75	1.26	0.69
Acylcarnitine C2:0	ME132836	1.40	1.01	0.81	1.11	1.13	1.02	1.01	1.03	1.07	1.01	0.95	1.07	0.37
PE 32:2	ME132859	0.68	0.71	0.66	0.74	0.92	1.10	1.28	1.07	1.18	1.19	1.42	1.07	1.05
PE 32:1	ME132860	0.79	0.79	0.69	0.78	0.86	1.11	1.14	1.04	1.15	1.16	1.26	1.09	1.19
PE 34:1	ME132864	0.86	0.89	0.77	0.76	0.87	1.10	1.08	0.98	1.18	1.13	1.32	0.99	1.11
lysoPE 16:0	ME132851	1.02	0.90	0.94	0.78	1.13	1.12	1.10	0.78	1.20	1.18	1.18	0.79	0.86
lysoPE 18:1	ME132852	1.04	1.00	1.18	0.86	1.07	1.07	1.29	0.83	1.02	1.05	1.17	0.77	0.66
lysoPC 18:1	ME132856	1.03	1.15	1.41	1.04	0.82	1.08	1.14	0.83	0.88	0.98	0.96	0.87	0.79
lysoPC 16:1	ME132854	0.85	1.06	1.13	0.94	0.77	1.15	1.32	0.94	0.93	1.11	1.09	0.99	0.73
Thiamine	ME132841	0.79	1.17	0.98	0.93	0.96	1.27	1.04	0.93	1.06	1.08	1.07	0.93	0.78
PC 36:2	ME132874	1.07	1.08	0.99	1.14	0.80	1.10	0.93	1.07	0.97	1.07	0.79	1.24	0.75
PC 36:3	ME132873	0.98	0.98	0.98	1.11	0.79	1.12	1.00	1.07	0.95	1.08	0.87	1.28	0.77
SM 34:1	ME132861	1.01	1.03	0.89	1.00	0.99	1.14	0.96	1.03	0.99	1.08	0.96	1.03	0.88
PC 34:4	ME132869	0.95	0.99	0.90	1.09	0.96	1.09	1.03	1.11	1.00	0.92	0.92	1.08	0.96
PC 34:2	ME132870	0.97	0.98	0.95	1.12	0.93	1.02	0.95	1.08	0.98	1.02	0.91	1.15	0.94
PC 34:1	ME132871	1.03	1.03	0.98	1.04	0.95	1.02	0.98	1.05	0.99	0.99	0.92	1.05	0.95
PC 38:5	ME132875	1.04	1.04	0.96	1.10	0.95	1.07	0.96	1.08	0.97	0.96	0.82	1.09	0.93
PC 38:3	ME132877	1.12	1.15	0.98	1.02	0.87	1.17	1.05	1.15	1.08	0.91	0.77	1.02	0.69
PC 38:4	ME132876	1.06	1.08	0.95	1.06	0.82	1.06	1.06	1.12	1.09	0.93	0.83	1.12	0.81
PC 40:7	ME132879	1.06	1.04	0.90	1.06	0.84	1.03	1.07	1.20	1.10	0.90	0.86	1.16	0.78
PE 38:6	ME132872	0.92	1.01	0.75	0.99	0.85	1.13	1.06	1.25	1.03	1.02	0.88	1.19	0.93
PE 36:3	ME132867	0.90	0.97	0.75	0.91	0.89	1.16	1.10	1.20	1.07	1.02	0.95	1.17	0.94
PE 36:4	ME132866	0.93	1.00	0.78	0.95	0.84	1.11	1.04	1.17	1.06	1.05	0.96	1.17	0.97
PE 36:2	ME132868	0.94	0.99	0.83	0.86	0.89	1.11	1.08	1.06	1.11	1.02	1.07	1.06	0.99
PE 34:2	ME132863	0.88	0.91	0.71	0.88	0.86	1.11	1.04	1.12	1.12	1.09	1.06	1.15	1.10
PE 34:3	ME132862	0.88	0.88	0.70	0.88	0.92	1.12	1.12	1.16	1.07	1.07	1.00	1.17	1.06
Betaine	ME132829	0.87	0.90	1.04	0.96	1.02	1.11	1.13	0.97	0.98	1.06	1.00	1.03	0.94
PC 32:2	ME132865	0.76	0.83	0.87	1.06	1.00	1.00	1.13	1.10	1.03	1.08	1.18	1.11	0.89
SM 32:1	ME132858	0.93	0.89	0.86	0.94	0.99	1.13	1.17	1.10	1.02	1.06	1.05	1.13	0.76
PC 38:2	ME132878	1.16	1.26	1.05	1.11	0.83	1.14	1.03	1.21	1.00	0.87	0.70	1.08	0.54
Phenylalanine	ME132835	0.89	1.08	0.99	1.10	1.07	1.31	1.07	1.16	0.98	0.90	0.65	1.09	0.67
Acylcarnitine C3:0	ME132837	0.87	1.10	1.00	0.82	0.98	1.39	0.97	0.80	1.10	1.15	0.75	0.74	1.27
lysoPE 18:0	ME132853	1.35	1.08	1.01	0.98	1.16	1.13	1.06	0.82	1.00	0.92	0.82	0.77	0.85
lysoPC 16:0	ME132855	1.12	1.25	1.17	1.02	0.92	1.16	0.96	0.78	0.96	1.05	0.79	0.84	0.91
lysoPC 18:0	ME132857	1.24	1.34	1.05	1.11	0.92	1.17	0.70	0.79	1.04	1.17	0.65	0.88	0.84

Factors:

F1	Treatment:10.5mM Glu \| Time:10min
F2	Treatment:10.5mM Glu \| Time:1hr
F3	Treatment:10.5mM Glu \| Time:24hr
F4	Treatment:10.5mM Glu \| Time:6hr
F5	Treatment:5.5mM Glu 5mM Fru \| Time:10min
F6	Treatment:5.5mM Glu 5mM Fru \| Time:1hr
F7	Treatment:5.5mM Glu 5mM Fru \| Time:24hr
F8	Treatment:5.5mM Glu 5mM Fru \| Time:6hr
F9	Treatment:5.5mM Glu \| Time:10min
F10	Treatment:5.5mM Glu \| Time:1hr
F11	Treatment:5.5mM Glu \| Time:24hr
F12	Treatment:5.5mM Glu \| Time:6hr
F13	Treatment:Glucosamine \| Time:10min

Data matrix