Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Metabolomic changes during active immunization with anti-METH vaccines. (Study ST000456)

Reversed phase POSITIVE ION MODE (Analysis AN000714)

Metabolite	Structure	F1	F2	F3	F4	F5
Putrescine	ME153208	0.21	2.03	0.11	0.03	1.30
Carnosine	ME153199	0.05	1.80	NA	NA	0.01
SDMA	ME153209	0.03	1.45	0.02	0.00	NA
alpha-AAA	ME153197	0.20	2.53	0.21	0.20	0.31
Kynurenine	ME153204	0.20	2.56	0.27	0.16	0.41
C8	ME153172	0.25	2.42	0.23	0.22	0.20
C12	ME153138	0.18	2.53	0.19	0.17	0.14
PC aa C24:0	ME153230	0.21	2.52	0.22	0.15	0.13
Spermine	ME153212	0.11	2.87	0.11	0.08	0.14
total DMA	ME153215	0.10	2.88	0.10	0.09	0.12
DOPA	ME153201	0.01	2.51	0.01	0.02	0.03
Histamine	ME153203	0.01	2.59	0.01	0.01	0.05
C18	ME153152	0.48	1.97	0.48	0.37	0.56
C5	ME153164	0.54	2.01	0.43	0.35	0.47
ADMA	ME153196	0.30	2.30	0.35	0.35	0.50
C14	ME153141	0.44	2.12	0.52	0.37	0.26
C10	ME153135	0.33	2.31	0.30	0.26	0.25
C6 (C4:1-DC)	ME153163	0.45	2.27	0.37	0.29	0.15
Creatinine	ME153200	0.96	2.08	0.40	0.31	0.25
C4	ME153161	0.82	1.77	0.58	0.59	0.32
C16	ME153146	0.63	1.85	0.70	0.47	0.40
PC ae C34:3	ME153276	0.76	1.71	0.81	0.56	0.45
t4-OH-Pro	ME153213	0.48	1.05	0.48	0.52	2.25
Met	ME153186	0.62	1.52	0.54	0.63	1.16
Met-SO	ME153205	0.59	1.47	0.79	0.83	0.89
Spermidine	ME153211	0.51	1.53	0.76	0.72	0.87
Ala	ME153174	0.66	1.07	0.77	0.80	1.57
Asn	ME153176	0.63	1.27	0.71	0.65	1.44
Pro	ME153189	0.65	1.18	0.63	0.72	1.57
Tyr	ME153193	0.57	1.29	0.59	0.61	1.59
Orn	ME153187	0.69	1.23	0.85	1.00	1.01
Phe	ME153188	0.77	1.24	0.76	0.91	1.06
Trp	ME153192	0.67	1.26	0.78	0.77	1.25
Asp	ME153177	0.79	1.29	0.80	0.74	1.10
His	ME153182	0.85	1.21	0.74	0.80	1.11
Val	ME153194	0.84	1.22	0.81	0.78	1.12
Glu	ME153180	0.63	1.05	0.93	1.08	1.23
Leu	ME153184	0.90	0.98	0.89	1.01	1.20
H1	ME153321	1.03	0.98	0.96	0.89	1.16
Ile	ME153183	0.94	1.08	0.88	0.91	1.09
Arg	ME153175	0.83	1.02	0.76	0.92	1.37
Lys	ME153185	0.79	1.00	0.82	0.94	1.38
Ser	ME153190	0.88	0.87	0.88	1.06	1.37
Thr	ME153191	0.83	0.91	0.96	1.00	1.35
C2	ME153156	1.73	0.80	1.45	1.18	0.20
lysoPC a C16:1	ME153218	1.64	0.79	1.58	0.95	0.45
lysoPC a C20:3	ME153223	1.53	0.83	1.49	0.87	0.61
C10:2	ME153137	1.76	1.03	0.71	0.79	0.57
PC aa C38:6	ME153255	1.51	0.98	1.20	0.66	0.74
PC aa C40:6	ME153261	1.67	0.89	1.11	0.65	0.82
PC aa C32:1	ME153236	1.58	1.16	1.00	0.63	0.47
PC aa C40:5	ME153260	1.42	1.30	1.05	0.71	0.48
PC aa C28:1	ME153232	0.91	1.42	0.98	0.66	0.60
SM C18:1	ME153314	0.97	1.38	0.94	0.74	0.60
C3	ME153157	0.75	1.54	0.74	0.69	0.66
C6:1	ME153170	0.86	1.46	0.76	0.71	0.67
PC ae C36:5	ME153282	0.90	1.46	0.83	0.61	0.68
PC aa C34:1	ME153239	1.35	1.11	1.04	0.71	0.68
C5-DC (C6-OH)	ME153169	1.38	0.98	0.91	0.86	0.85
C5:1-DC	ME153168	1.26	1.05	0.93	0.87	0.82
C9	ME153173	1.28	1.10	0.86	0.85	0.76
PC ae C44:6	ME153305	1.21	1.14	1.23	0.80	0.56
PC ae C42:4	ME153300	1.12	1.29	1.17	0.88	0.55
PC ae C36:3	ME153280	1.06	1.26	1.14	0.77	0.59
PC ae C44:5	ME153304	1.09	1.24	1.13	0.76	0.59
SM (OH) C14:1	ME153306	1.10	1.22	1.00	0.85	0.64
SM (OH) C16:1	ME153307	1.08	1.21	1.06	0.85	0.68
Ac-Orn	ME153195	1.01	1.25	0.91	0.89	0.71
C10:1	ME153136	1.05	1.20	0.95	0.89	0.68
C12:1	ME153140	1.16	1.21	0.90	0.78	0.70
PC ae C38:6	ME153289	1.11	1.28	1.01	0.68	0.68
SM C18:0	ME153313	1.05	1.25	0.98	0.77	0.69
Cit	ME153178	1.01	1.15	1.18	0.87	0.72
SM C16:1	ME153312	1.15	1.10	1.07	0.89	0.70
C14:2-OH	ME153145	0.88	1.30	0.90	0.81	0.77
C12-DC	ME153139	0.91	1.18	0.90	0.88	0.92
C5-M-DC	ME153165	0.89	1.27	0.78	0.86	0.85
Gly	ME153181	0.85	1.25	0.78	0.91	0.96
PC aa C36:5	ME153248	1.20	1.18	1.04	0.62	0.79
PC aa C30:0	ME153233	1.08	1.19	1.01	0.71	0.81
PC ae C36:4	ME153281	1.10	1.15	0.99	0.69	0.91
PC ae C38:5	ME153288	1.06	1.18	0.99	0.69	0.88
C5:1	ME153167	1.04	1.19	0.83	0.85	0.83
C4:1	ME153162	1.10	1.17	0.83	0.86	0.80
C7-DC	ME153171	1.08	1.16	0.88	0.84	0.83
C3:1	ME153160	1.15	1.06	0.87	0.87	0.95
C5-OH (C3-DC-M)	ME153166	1.00	1.07	0.95	1.00	0.89
C16:2-OH	ME153151	1.01	1.14	0.98	0.87	0.86
C3-OH	ME153159	1.06	1.09	0.96	0.86	0.92
C0	ME153134	1.07	0.80	1.23	1.34	0.82
PC ae C38:3	ME153286	1.16	0.90	1.26	0.86	1.01
PC ae C40:3	ME153292	1.12	0.82	1.20	0.97	1.14
C16-OH	ME153147	1.14	0.86	1.21	0.90	1.09
SM (OH) C24:1	ME153310	1.20	0.80	1.23	0.92	1.10
Serotonin	ME153210	0.97	0.90	1.19	1.02	1.08
Taurine	ME153214	1.05	0.82	1.08	1.09	1.12
PC aa C36:4	ME153247	1.27	1.00	1.03	0.62	1.09
PC aa C34:2	ME153240	1.31	0.95	1.12	0.71	1.02
SM C22:3	ME153316	1.33	0.91	1.08	0.66	1.15
PC aa C32:0	ME153235	1.31	0.85	1.11	0.77	1.14
PC aa C38:4	ME153253	1.37	0.88	1.10	0.72	1.09
lysoPC a C18:2	ME153222	1.37	0.79	1.29	0.77	1.10
lysoPC a C20:4	ME153224	1.43	0.78	1.28	0.60	1.24
SM (OH) C22:2	ME153309	1.31	0.92	1.36	1.12	0.49
PC aa C38:1	ME153251	1.27	0.76	1.63	1.10	0.70
lysoPC a C17:0	ME153219	1.31	0.77	1.50	1.27	0.54
lysoPC a C18:1	ME153221	1.31	0.79	1.46	1.17	0.64
C3-DC (C4-OH)	ME153158	1.52	0.82	1.22	1.03	0.67
lysoPC a C16:0	ME153217	1.32	0.79	1.32	1.05	0.84
lysoPC a C24:0	ME153225	1.27	0.78	1.35	1.12	0.82
lysoPC a C18:0	ME153220	1.32	0.77	1.31	1.18	0.76
SM (OH) C22:1	ME153308	1.34	0.82	1.24	1.13	0.73
SM C24:0	ME153317	1.30	0.80	1.22	1.05	0.90
SM C26:0	ME153319	1.31	0.79	1.21	1.03	0.94
lysoPC a C14:0	ME153216	1.23	0.76	1.30	1.10	0.96
SM C26:1	ME153320	1.21	0.80	1.32	1.00	0.96
lysoPC a C28:1	ME153229	1.42	0.83	1.34	0.82	0.87
PC ae C40:1	ME153290	1.50	0.77	1.37	0.80	0.90
PC aa C40:2	ME153257	1.20	0.76	1.47	1.01	0.95
PC ae C42:1	ME153297	1.28	0.78	1.45	0.91	0.94
C18:2	ME153155	1.39	0.84	1.50	0.88	0.71
PC ae C42:3	ME153299	1.43	0.81	1.50	0.91	0.71
PC ae C42:2	ME153298	1.40	0.79	1.54	0.99	0.68
PC aa C42:2	ME153264	1.35	0.79	1.52	0.99	0.73
PC ae C44:3	ME153302	1.35	0.79	1.51	0.94	0.78
PC aa C40:3	ME153258	1.24	0.83	1.47	1.01	0.76
PC aa C42:1	ME153263	1.28	0.85	1.48	0.97	0.73
PC ae C38:2	ME153285	1.29	0.83	1.49	1.00	0.73
C18:1	ME153153	1.27	0.81	1.41	1.03	0.81
PC aa C42:4	ME153265	1.29	0.79	1.43	0.98	0.87
PC ae C36:1	ME153278	1.21	0.93	1.32	0.82	0.89
PC aa C36:0	ME153243	1.29	0.86	1.33	0.88	0.89
PC ae C30:1	ME153269	1.28	0.84	1.36	0.88	0.88
PC aa C42:0	ME153262	1.23	0.87	1.39	0.91	0.85
PC ae C38:1	ME153284	1.21	0.86	1.37	0.91	0.91
PC aa C40:1	ME153256	1.17	0.93	1.44	0.94	0.73
PC ae C44:4	ME153303	1.25	0.93	1.40	0.97	0.66
PC aa C38:0	ME153250	1.24	0.95	1.42	0.89	0.69
PC ae C36:2	ME153279	1.28	0.90	1.42	0.90	0.73
PC ae C40:2	ME153291	1.28	0.87	1.36	0.99	0.74
PC ae C40:5	ME153294	1.27	0.90	1.34	0.92	0.78
lysoPC a C26:0	ME153226	1.30	0.88	1.32	0.92	0.81
PC ae C34:0	ME153273	1.31	0.85	1.32	0.95	0.81
lysoPC a C26:1	ME153227	1.25	0.83	1.33	0.99	0.86
PC ae C40:4	ME153293	1.31	0.83	1.35	0.98	0.82
PC aa C40:4	ME153259	1.37	0.90	1.30	0.87	0.77
PC ae C36:0	ME153277	1.33	0.90	1.30	0.94	0.72
PC aa C42:5	ME153266	1.35	0.86	1.41	0.94	0.73
PC ae C30:2	ME153270	1.33	0.84	1.39	0.94	0.78
PC ae C38:0	ME153283	1.38	0.90	1.36	0.86	0.71
lysoPC a C28:0	ME153228	1.40	0.86	1.37	0.90	0.74
PC aa C42:6	ME153267	1.38	0.87	1.38	0.92	0.70
Gln	ME153179	1.09	1.07	1.08	0.80	0.93
PC aa C26:0	ME153231	1.13	1.04	1.11	0.81	0.90
PC aa C36:2	ME153245	1.32	0.92	1.18	0.78	0.93
PC ae C34:1	ME153274	1.23	0.94	1.20	0.87	0.90
PC ae C38:4	ME153287	1.25	0.98	1.20	0.79	0.87
PC ae C30:0	ME153268	1.21	0.94	1.19	0.95	0.83
PC ae C42:5	ME153301	1.22	0.95	1.18	0.94	0.83
C18:1-OH	ME153154	1.16	0.94	1.19	0.98	0.86
SM C24:1	ME153318	1.21	0.90	1.17	0.99	0.88
PC ae C32:1	ME153271	1.18	1.02	1.18	0.88	0.77
PC ae C42:0	ME153296	1.13	1.05	1.19	0.90	0.75
PC aa C30:2	ME153234	1.21	0.99	1.11	0.90	0.84
SM C16:0	ME153311	1.16	1.03	1.08	0.89	0.85
PC aa C36:6	ME153249	1.29	1.04	1.26	0.74	0.73
PC ae C34:2	ME153275	1.22	1.02	1.27	0.85	0.72
PC aa C32:3	ME153238	1.25	1.04	1.25	0.82	0.69
PC aa C36:3	ME153246	1.24	1.04	1.27	0.79	0.72
PC aa C34:3	ME153241	1.42	0.95	1.35	0.79	0.66
PC aa C32:2	ME153237	1.43	0.99	1.30	0.75	0.64
PC aa C34:4	ME153242	1.42	1.02	1.30	0.70	0.64
PC aa C36:1	ME153244	1.41	0.96	1.19	0.86	0.68
PC aa C38:5	ME153254	1.44	0.97	1.21	0.82	0.65
PC aa C38:3	ME153252	1.36	1.02	1.22	0.82	0.64
PC ae C40:6	ME153295	1.34	0.98	1.33	0.82	0.65
SM C20:2	ME153315	1.35	1.00	1.28	0.82	0.64
C14:1	ME153142	1.21	0.89	1.36	1.09	0.70
C16:1-OH	ME153149	1.17	0.92	1.31	1.00	0.79
C16:1	ME153148	1.11	1.06	1.32	0.96	0.59
C16:2	ME153150	1.25	1.04	1.20	0.93	0.61
C14:2	ME153144	1.27	0.96	1.22	1.02	0.65
C14:1-OH	ME153143	1.19	0.99	1.30	0.99	0.64
PC ae C32:2	ME153272	1.21	1.00	1.26	0.93	0.68

Factors:

F1	MCV:Act KLH \| Adjuvant:RIBI \| Sample Collection:Immunized (17 wks)
F2	MCV:- \| Adjuvant:- \| Sample Collection:-
F3	MCV:SSM09 \| Adjuvant:None \| Sample Collection:Immunized (17 wks)
F4	MCV:SSM09 \| Adjuvant:RIBI \| Sample Collection:Immunized (17 wks)
F5	MCV:SSM09 \| Adjuvant:RIBI \| Sample Collection:Pre-Immune (0 wks)

Data matrix