Clustering data with hclust algorithm for Investigating TCA concentrations in mice muscle tissue lacking insulin receptors and IGF-1 receptors (Study ST000512)
GC POSITIVE ION MODE (Analysis AN000785)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|---|
| cis-Aconitic Acid | ME157246 | 0.52 | 2.61 | 0.65 | 0.52 | 1.25 | 0.73 | 1.04 | 1.04 |
| Ketoglutarate | ME157243 | 0.41 | 0.95 | 0.41 | 0.89 | 0.66 | 0.47 | 0.47 | 2.69 |
| Isocitrate | ME157248 | 0.91 | 0.36 | 1.79 | 1.53 | 0.66 | 0.98 | 1.29 | 0.51 |
| Lactate | ME157239 | 1.14 | 1.26 | 1.27 | 1.11 | 1.27 | 0.98 | 0.91 | 0.39 |
| Oxaloacetate | ME157242 | 0.68 | 1.24 | 1.36 | 1.40 | 0.69 | 0.72 | 0.79 | 1.29 |
| Succinate | ME157240 | 1.28 | 0.59 | 1.08 | 1.24 | 1.13 | 1.05 | 0.75 | 0.90 |
| Glutamate | ME157245 | 0.70 | 0.73 | 1.00 | 1.06 | 0.81 | 0.93 | 0.77 | 1.73 |
| Citrate | ME157247 | 0.84 | 0.95 | 1.03 | 0.91 | 1.02 | 1.10 | 0.74 | 1.32 |
| Fumarate | ME157241 | 0.96 | 0.71 | 0.97 | 1.11 | 0.84 | 1.07 | 0.81 | 1.38 |
| Malate | ME157244 | 0.97 | 0.72 | 0.96 | 1.09 | 0.84 | 1.07 | 0.81 | 1.39 |
Factors:
| F1 | Group:CD | Genotype:Irlox | Diet:Chow |
| F2 | Group:Control | Genotype:IGFR lox | Diet:Chow |
| F3 | Group:Control | Genotype:Irlox | Diet:Chow |
| F4 | Group:Control | Genotype:IRlox IGFR lox | Diet:Chow |
| F5 | Group:HFD | Genotype:Irlox | Diet:High Fat Diet |
| F6 | Group:IGFRKO | Genotype:IGFR -/- | Diet:Chow |
| F7 | Group:IRKO | Genotype:IR -/- | Diet:Chow |
| F8 | Group:MIGIRKO | Genotype:IR -/- IGFR -/- | Diet:Chow |
