Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Inhibition of autophagy/proteasome degradation or inhibition of protein synthesis in models of muscle insulin resistance affect amino acids metabolites in serum (Study ST000514)

Reversed phase POSITIVE ION MODE (Analysis AN000787)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12
gamma-Amino-N-butyric-acid	ME157270	0.94	0.84	0.84	5.02	0.56	1.95	0.42	1.05	0.84	1.05	0.70	0.56
alpha-Amino-N-butyric-acid	ME157275	0.39	0.63	0.28	0.45	0.46	0.48	0.58	1.14	0.39	4.88	0.37	0.39
Cystine	ME157294	0.91	2.05	1.75	0.18	0.89	0.92	0.65	1.10	1.47	0.89	0.97	0.83
Glycine	ME157286	0.96	1.12	0.88	1.02	1.14	1.24	0.90	0.72	1.13	0.72	1.05	1.13
Histidine	ME157259	0.93	0.80	1.06	1.09	1.19	1.55	0.73	0.64	0.87	1.14	0.83	1.10
Tyrosine	ME157295	1.04	1.16	0.89	1.05	1.42	1.34	0.53	0.67	0.81	1.03	0.85	1.01
Citrulline	ME157287	1.25	1.53	0.94	1.06	1.03	1.14	0.78	0.90	1.08	1.24	0.81	0.70
Proline	ME157291	1.09	1.47	1.03	0.77	1.18	1.25	0.63	0.77	1.13	1.15	0.79	0.89
Hydroxyproline	ME157260	1.17	1.20	1.35	0.77	1.06	1.13	0.59	0.55	0.85	0.93	1.05	1.10
Arginine	ME157282	1.34	1.22	1.21	0.66	1.29	1.02	0.74	0.74	0.73	0.89	0.99	0.91
Methionine	ME157278	1.15	1.39	1.18	0.53	1.34	1.13	0.74	0.70	0.96	1.01	0.88	0.94
Ornithine	ME157292	0.91	0.77	1.09	0.86	1.23	0.94	0.53	0.61	1.04	1.54	0.92	1.10
Phosphoethanolamine	ME157263	0.97	0.75	1.38	1.06	0.79	0.95	0.97	1.05	0.87	1.21	0.98	1.03
Aspartic Acid	ME157267	1.38	0.77	1.35	1.15	0.89	0.89	0.73	0.85	0.92	1.17	0.93	0.96
Glutamic Acid	ME157288	1.30	0.74	1.29	1.17	1.05	0.86	0.86	0.75	0.73	1.26	1.02	0.90
alpha-Aminoadipic-acid	ME157271	0.84	1.01	1.34	0.41	1.00	0.60	1.15	1.29	1.16	1.45	0.89	0.91
Ethanolamine	ME157266	1.05	1.03	0.88	1.35	0.80	1.28	1.11	1.04	1.38	1.36	0.78	0.75
Lysine	ME157293	0.98	1.03	1.04	0.51	1.08	0.80	0.88	0.81	1.29	1.28	0.96	1.10
Threonine	ME157289	0.97	0.99	1.05	0.53	1.10	0.82	1.07	0.99	1.29	1.34	0.89	0.97
Alanine	ME157290	0.93	1.38	0.85	0.77	0.90	1.16	0.71	1.00	1.34	1.43	0.76	0.90
Asparagine	ME157281	0.89	1.21	0.82	0.97	0.88	1.13	0.76	1.09	1.17	1.36	0.82	0.92
Taurine	ME157283	1.14	0.95	0.99	0.81	0.91	0.89	1.05	1.07	1.10	1.53	0.86	0.77
Glutamine	ME157285	0.92	1.11	1.02	1.10	0.83	0.95	0.89	1.15	1.16	1.31	0.88	0.91
Serine	ME157284	0.89	0.98	0.96	0.85	0.93	1.01	0.90	0.99	1.18	1.24	0.95	1.02
Valine	ME157296	1.05	1.01	0.91	0.72	1.01	0.97	0.84	0.99	1.17	1.24	0.96	0.93
3-Methylhistidine	ME157262	0.94	1.81	1.06	0.54	1.08	1.53	1.52	0.73	0.77	0.88	0.93	0.81
Cystathionine 1	ME157276	1.54	2.26	0.83	0.34	1.21	0.96	1.57	0.75	0.54	1.21	0.65	0.62
Hydroxylysine 2	ME157274	0.77	0.88	1.32	0.44	2.13	1.32	NA	NA	0.22	NA	0.66	0.92
beta-alanine	ME157269	1.67	2.68	0.62	1.03	1.68	1.17	0.31	NA	0.51	0.10	1.06	0.86
Sarcosine	ME157268	1.37	2.22	0.57	0.91	1.41	0.95	0.23	0.23	0.34	0.57	0.93	0.76

Factors:

F1	Group:Control colch \| Genotype:Irlox IGFRlox \| Treatment:Colch
F2	Group:Control colch \| Genotype:Irlox \| Treatment:Colch
F3	Group:Control colch \| Genotype:- \| Treatment:Colch
F4	Group:control \| Genotype:IR -/- IGFR -/- \| Treatment:saline
F5	Group:control \| Genotype:Irlox IGFRlox \| Treatment:saline
F6	Group:control \| Genotype:Irlox \| Treatment:saline
F7	Group:HFD + Colch \| Genotype:Irlox IGFRlox \| Treatment:Colch
F8	Group:HFD + Colch \| Genotype:Irlox \| Treatment:Colch
F9	Group:HFD \| Genotype:Irlox IGFRlox \| Treatment:saline
F10	Group:HFD \| Genotype:Irlox \| Treatment:saline
F11	Group:MIGIRKO colch \| Genotype:IR -/- IGFR -/- \| Treatment:Colch
F12	Group:MIGIRKO \| Genotype:IR -/- IGFR -/- \| Treatment:saline

Data matrix