Clustering data with hclust algorithm for Effects of Curcumin Supplementation on the Amino Acid Concentration of Older Adults: Relation to Vascular Function (Study ST000524)
Reversed phase POSITIVE ION MODE (Analysis AN000802)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 |
|---|---|---|---|---|---|---|
| Cystathionine 1 | ME158182 | 0.59 | 0.81 | 1.56 | 1.31 | 0.40 |
| Aspartic Acid | ME158173 | 0.85 | 0.70 | 0.95 | 1.03 | 1.53 |
| Hydroxylysine 2 | ME158180 | 0.94 | 0.72 | 1.26 | 0.80 | 1.46 |
| gamma-Amino-N-butyric-acid | ME158176 | 1.29 | 1.00 | 0.82 | 0.80 | 1.03 |
| Phosphoethanolamine | ME158169 | 1.13 | 0.76 | 1.18 | 0.92 | 1.03 |
| Glycine | ME158192 | 1.06 | 1.05 | 0.96 | 0.98 | 0.93 |
| Glutamine | ME158191 | 1.04 | 1.04 | 0.97 | 0.97 | 0.97 |
| Serine | ME158190 | 1.04 | 1.03 | 0.95 | 0.99 | 0.99 |
| Lysine | ME158199 | 0.98 | 1.04 | 1.01 | 1.05 | 0.92 |
| Leucine | ME158204 | 0.98 | 1.00 | 0.99 | 1.01 | 1.01 |
| Ethanolamine | ME158172 | 0.99 | 1.02 | 0.99 | 1.03 | 0.97 |
| Valine | ME158202 | 0.98 | 1.01 | 1.00 | 1.02 | 0.98 |
| Histidine | ME158165 | 1.02 | 0.88 | 1.02 | 1.04 | 1.06 |
| Asparagine | ME158187 | 1.00 | 0.97 | 0.96 | 1.02 | 1.06 |
| Phenylalanine | ME158205 | 1.00 | 0.97 | 0.98 | 0.98 | 1.08 |
| beta-Alanine | ME158175 | 0.99 | 0.97 | 0.99 | 1.00 | 1.06 |
| Sarcosine | ME158174 | 1.00 | 0.97 | 1.00 | 0.99 | 1.04 |
| Isoleucine | ME158203 | 0.99 | 0.95 | 0.97 | 1.00 | 1.11 |
| Methionine | ME158184 | 1.00 | 0.96 | 0.93 | 0.99 | 1.13 |
| Threonine | ME158195 | 1.00 | 0.99 | 0.92 | 0.98 | 1.12 |
| Arginine | ME158188 | 0.94 | 0.95 | 0.99 | 1.06 | 1.08 |
| Tyrosine | ME158201 | 0.96 | 0.96 | 1.05 | 1.02 | 1.03 |
| Proline | ME158197 | 0.96 | 0.92 | 0.95 | 0.94 | 1.25 |
| Alanine | ME158196 | 0.97 | 0.96 | 0.92 | 0.97 | 1.19 |
| Tryptophan | ME158206 | 0.94 | 0.93 | 0.99 | 0.98 | 1.19 |
| Glutamic Acid | ME158194 | 0.93 | 0.86 | 1.07 | 1.04 | 1.13 |
| Hydroxyproline | ME158166 | 0.83 | 0.91 | 1.06 | 1.06 | 1.18 |
| 3-Methylhistidine | ME158168 | 1.16 | 1.05 | 1.13 | 1.04 | 0.60 |
| 1-Methylhistidine | ME158167 | 1.04 | 1.14 | 1.02 | 0.90 | 0.84 |
| allo-Isoleucine | ME158185 | 1.11 | 1.14 | 0.89 | 0.95 | 0.85 |
| alpha-Amino-N-butyric-acid | ME158181 | 1.09 | 1.13 | 0.97 | 0.97 | 0.82 |
| alpha-Aminoadipic-acid | ME158177 | 0.99 | 1.03 | 1.12 | 1.02 | 0.83 |
| Taurine | ME158189 | 0.98 | 0.94 | 1.04 | 1.17 | 0.89 |
| Citrulline | ME158193 | 0.99 | 0.97 | 1.06 | 1.13 | 0.86 |
| Ornithine | ME158198 | 0.96 | 0.99 | 1.07 | 1.09 | 0.89 |
| beta-Aminoisobutyric-acid | ME158178 | 1.03 | 1.04 | 1.13 | 1.19 | 0.61 |
| Cystine | ME158200 | 0.95 | 1.04 | 1.08 | 1.18 | 0.75 |
Factors:
| F1 | group:Old-Curcumin | Time point:Post |
| F2 | group:Old-Curcumin | Time point:Pre |
| F3 | group:Old-Placebo | Time point:Post |
| F4 | group:Old-Placebo | Time point:Pre |
| F5 | group:young | Time point:Baseline |
