Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Large Scale C18 Profiling of the Effects of Curcumin Supplementation of Older Adults: Relation to Vascular Function (Study ST000566)

Reversed phase NEGATIVE ION MODE (Analysis AN000869)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
Prasterone sulfate - 7.9986095	ME167760	0.39	0.14	0.11	0.33	4.14	NA
N-Methyl-2,3,7,8-tetramethoxy-5,6-dihydrobenzophenathridine-6-ethanoic acid	ME167806	0.27	0.21	0.47	0.34	3.84	NA
AMCC	ME167727	0.20	0.49	0.35	0.46	3.60	NA
Mesuagin	ME167802	0.15	0.51	0.22	0.45	3.77	NA
6-dehydrotestosterone 17-glucosiduronic acid	ME167766	0.84	1.32	1.66	0.81	0.38	NA
Trp His Glu	ME167765	0.90	1.47	1.76	0.78	0.08	NA
4-Methylumbelliferyl ?-D-glucuronide	ME167714	1.20	1.57	1.07	0.57	0.45	NA
Quinic acid	ME167722	1.28	1.61	0.72	0.95	0.29	NA
AFMK	ME167736	1.09	1.16	1.09	1.34	0.31	NA
2-Hydroxy-3-(4-methoxyethylphenoxy)-propanoic acid	ME167762	0.87	1.01	1.36	1.51	0.32	NA
Phenyl beta-D-glucopyranoside	ME167744	0.90	1.04	1.43	1.50	0.20	NA
3b,16a-Dihydroxyandrostenone sulfate	ME167746	0.74	0.72	1.17	1.35	1.12	NA
4-Hydroxybenzenesulfonic acid	ME167735	1.41	0.96	0.87	0.97	0.73	NA
Phenol	ME167733	1.46	0.87	0.83	1.03	0.76	NA
2^-Deoxyuridine	ME167708	0.69	1.21	1.05	1.21	0.86	NA
Quinol sulfate	ME167729	0.94	0.77	1.21	1.02	1.11	NA
4-Hydroxylevamisole Glucuronide	ME167750	0.96	0.92	1.06	1.13	0.97	NA
3-keto-n-caproic acid	ME167732	0.91	0.91	1.06	1.03	1.14	NA
Tryptophan	ME167731	0.96	0.94	0.97	1.00	1.14	NA
Hydroxyibuprofen	ME167792	1.00	0.97	0.92	1.02	1.09	NA
Tris(2-chloroethyl)phosphate	ME167730	1.04	0.92	0.94	0.99	1.11	NA
Z-Arg-Arg-NHMec	ME167772	1.22	1.10	0.72	1.19	0.72	NA
2,4-Dichloro-3-oxoadipate	ME167662	1.05	1.01	1.06	1.05	0.82	NA
Phosphonoacetate	ME167661	1.02	0.99	1.02	1.04	0.93	NA
Fluroxypyr	ME167657	1.04	1.02	1.01	1.05	0.87	NA
Uric acid	ME167726	1.02	1.02	1.04	1.04	0.89	NA
MID42238:(6R)-1?,25-dihydroxyvitamin D3 6,19-sulfur dioxide adduct / (6R)-1?,25-dihydroxycholecalcif	ME167768	1.03	1.08	1.03	1.09	0.76	NA
edetate	ME167707	1.05	1.11	0.94	1.04	0.83	NA
5,7,4^-Trihydroxyflavanone 7-sulfate	ME167689	1.03	1.08	0.95	1.08	0.85	NA
Sulfamethizole	ME167695	1.03	1.10	0.94	1.07	0.85	NA
floxuridine	ME167711	1.06	1.02	1.00	1.12	0.79	NA
Distemonanthin - 0.9142415	ME167687	1.09	1.02	0.94	1.09	0.85	NA
6-Thioxanthine 5^-monophosphate	ME167787	1.10	1.05	0.97	1.06	0.80	NA
Valdecoxib	ME167697	1.05	1.06	0.98	1.08	0.83	NA
Carboxytolbutamide	ME167690	1.06	1.04	0.98	1.06	0.84	NA
Distemonanthin	ME167685	1.06	1.04	0.98	1.08	0.83	NA
2-Pyridylthioamide	ME167784	1.04	1.02	1.19	0.94	0.81	NA
Creatinine	ME167724	1.10	0.94	1.14	1.05	0.78	NA
Dolichol-16	ME167740	1.02	1.01	1.12	1.10	0.76	NA
5-Dehydro-4-deoxy-D-glucarate	ME167725	1.21	1.19	0.89	1.04	0.61	NA
Gluconic acid	ME167710	1.13	1.18	0.93	1.02	0.68	NA
7-Hydroxymethotrexate	ME167712	1.04	1.15	0.95	1.08	0.76	NA
Sulfinpyrazone sulfone	ME167719	1.00	1.14	0.93	1.13	0.78	NA
Mahuannin D	ME167705	1.09	1.15	0.96	1.10	0.67	NA
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine	ME167698	1.10	1.10	0.94	1.10	0.73	NA
Millettosin	ME167720	1.14	1.16	0.84	1.09	0.72	NA
Proanthocyanidin A2	ME167703	1.08	1.18	0.89	1.12	0.69	NA
5-O-Feruloylquinic acid	ME167717	1.03	1.23	0.79	1.08	0.83	NA
11-methyl-tridecanoic acid	ME167776	1.06	1.14	0.84	0.99	0.94	NA
6-Gingerol	ME167781	1.12	1.05	0.83	1.10	0.87	NA
Herbimycin	ME167767	1.09	1.11	0.81	1.12	0.84	NA
TG(22:0/22:0/22:0)	ME167734	1.24	0.92	1.01	1.09	0.72	NA
5,8-Dihydroxy-3,4-dihydrocarbostyril	ME167737	1.16	0.99	1.03	1.14	0.68	NA
N(6)-Methyllysine	ME167706	1.16	0.98	1.01	1.19	0.66	NA
Fagomine	ME167721	1.11	0.86	1.17	1.27	0.63	NA
p-cresol	ME167742	1.00	1.07	1.11	1.20	0.63	NA
17-?, 21-dihydroxy-11,20-dioxo-5-?-pregnan-3-?-yl-?-d-glucuronide	ME167801	0.98	1.05	1.12	1.20	0.66	NA
4-Sulfobenzyl alcohol	ME167741	0.97	1.03	1.12	1.21	0.69	NA
12-oxo-14,18-dihydroxy-9Z,13E,15Z-octadecatrienoic acid	ME167774	1.04	1.10	0.68	0.82	1.29	NA
11E-octadecen-9-ynoic acid	ME167775	1.27	1.37	0.39	1.05	0.79	NA
6E,9E-octadecadienoic acid	ME167777	1.19	1.40	0.43	0.96	0.89	NA
Trilauroyl-glycerol	ME167794	1.24	1.42	0.39	0.87	0.93	NA
13Z-octadecenoic acid	ME167780	1.13	1.39	0.56	1.10	0.72	NA
36:4(21Z,24Z,27Z,30Z)	ME167779	1.05	1.30	0.56	1.12	0.89	NA
Tauroursodeoxycholic acid	ME167791	0.35	0.19	1.71	1.56	1.49	NA
Steryl sulfate	ME167745	0.24	0.35	0.77	0.96	2.86	NA
5?-Androstan-3?-ol-17-one sulfate - 8.185043	ME167761	0.48	0.45	0.64	0.76	2.78	NA
pregnenolone sulfate	ME167763	0.43	0.45	0.59	0.79	2.85	NA
His Cys His	ME167757	0.58	0.64	0.71	0.82	2.34	NA
Lactacystin	ME167753	0.50	0.60	0.73	0.98	2.31	NA
Marinobufagenin	ME167759	0.46	0.88	0.62	1.21	1.91	NA
5?-Androstan-3?-ol-17-one sulfate	ME167748	0.56	0.62	0.94	1.08	1.92	NA
Deoxycholic acid glycine conjugate	ME167764	0.85	0.58	0.72	0.98	1.92	NA
5?-Androstan-3?-ol-17-one sulfate - 7.7291727	ME167758	0.69	0.72	0.72	0.85	2.08	NA
Lys His Cys	ME167743	0.72	0.69	0.75	1.02	1.89	NA
Glu Glu Met	ME167751	0.65	0.69	0.77	0.99	1.98	NA
Prasterone sulfate	ME167752	0.63	0.67	0.78	0.99	2.01	NA
Allopregnanalone sulfate	ME167756	0.67	0.69	0.83	0.92	1.96	NA
Lys Met His	ME167749	0.67	0.68	0.88	0.97	1.89	NA
2-Aminoadenosine	ME167805	0.77	0.68	0.99	0.85	1.77	NA
5?-Androstan-3?-ol-17-one sulfate - 7.5459185	ME167754	0.68	0.82	0.84	1.01	1.72	NA

Factors:

F1	group:Old-Curcumin \| Time point:Post
F2	group:Old-Curcumin \| Time point:Pre
F3	group:Old-Placebo \| Time point:Post
F4	group:Old-Placebo \| Time point:Pre
F5	group:young \| Time point:Baseline
F6	group:young \| Time point:Pre

Data matrix