Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Slow Aging Mice Plasma Metabolomics (Study ST000705)

Reversed phase POSITIVE ION MODE (Analysis AN001095)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15	F16	F17
CHOLIC ACID (2M+H)+	ME199288	0.03	0.01	0.72	1.44	0.09	0.24	0.08	0.86	2.83	3.53	0.00	0.00	NA	2.90	1.21	0.05	0.00
CHOLIC ACID (2M+NA)+	ME199289	0.10	0.03	0.86	1.49	0.35	0.55	0.27	1.09	2.86	1.98	0.02	0.01	NA	4.11	1.07	0.12	0.04
GLYCOCHOLIC ACID (M+H)+	ME199302	0.02	NA	0.20	0.14	1.04	0.03	0.07	0.04	2.86	0.06	0.03	NA	NA	3.22	0.07	0.06	NA
GLYCOCHOLIC ACID (M+NA)+	ME199303	0.03	NA	0.29	0.14	1.67	0.04	0.16	0.05	2.25	0.07	0.03	0.09	NA	3.26	0.07	0.07	NA
DIPALMITOYL-GLYCEROL (M+NA)+	ME199295	0.50	0.39	0.69	0.39	3.82	0.76	0.64	0.59	1.94	0.48	0.41	0.32	NA	2.48	0.45	0.61	0.47
DIPALMITOYL-GLYCEROL (M+H)+[-H2O]	ME199294	NA	NA	0.57	0.37	2.24	0.68	0.27	0.27	1.81	0.24	0.60	0.16	NA	2.85	0.33	0.27	0.27
LAUROYLCARNITINE (M+H)+	ME199309	0.35	0.70	1.15	0.50	2.65	0.81	0.77	0.40	2.67	0.13	0.40	0.06	NA	2.61	0.30	0.68	0.15
11-DEOXYCORTICOSTERONE (M+H)+	ME199272	0.49	0.18	0.70	0.32	2.71	0.58	3.56	0.46	0.58	0.34	0.59	0.08	NA	0.49	1.64	1.21	0.49
NORADRENALINE (M+H)+[-H2O]	ME199320	0.91	0.82	0.72	0.67	2.80	0.83	2.25	0.60	0.61	0.68	0.55	0.66	NA	0.49	0.48	2.35	0.73
GLUTATHIONE OXIDIZED (M+H)+	ME199301	0.16	0.18	0.80	1.21	1.22	0.61	0.82	0.42	1.76	1.35	0.63	1.11	NA	3.12	0.58	0.53	0.97
2^-DEOXYGUANOSINE (M+H)+	ME199275	0.83	1.46	0.54	0.33	1.02	0.41	0.52	0.31	1.30	0.68	1.77	1.47	NA	2.04	0.75	0.67	0.49
ADENOSINE 5^-MONOPHOSPHATE (M+H)+	ME199281	0.74	0.72	0.76	0.50	1.00	0.61	0.63	0.47	1.05	0.94	1.72	1.41	NA	3.33	0.93	0.46	0.51
DEOXYURIDINE (M+NA)+	ME199293	NA	NA	1.08	1.25	0.53	0.96	0.71	1.26	1.73	1.33	0.21	0.24	NA	1.11	1.22	0.46	0.86
THYMIDINE (M+NA)+	ME199337	0.30	0.34	1.27	1.49	0.52	1.17	0.94	1.49	1.97	1.70	0.37	0.39	NA	1.23	1.53	0.60	0.78
OLEOYL-GLYCEROL (M+H)+	ME199321	0.14	0.13	1.02	0.68	1.73	1.24	1.05	0.87	2.55	0.82	0.49	0.58	NA	1.59	0.94	0.88	0.77
OLEOYL-GLYCEROL (M+H)+[-H2O]	ME199322	0.16	0.20	1.06	0.68	1.39	1.21	1.44	0.88	1.61	1.15	0.63	0.67	NA	1.77	0.91	0.85	1.17
BUTYRYLCARNITINE (*) (M+H)+	ME199285	0.24	0.29	0.76	0.63	2.05	0.67	0.83	0.94	0.73	0.56	0.69	0.46	NA	1.12	1.88	2.20	1.80
HEXANOYLCARNITINE (*) M+	ME199305	0.34	0.48	0.81	0.86	1.52	1.27	1.10	1.08	0.79	0.92	0.65	0.52	NA	0.98	1.35	1.97	1.25
PHENYLALANINE (M+H)+	ME199326	1.15	1.27	1.17	0.80	0.42	0.46	0.41	1.64	0.78	1.97	1.18	1.00	NA	0.42	0.65	1.45	1.53
METHYL INDOLE-3-ACETATE (M+H)+	ME199314	1.60	1.07	0.95	0.20	1.36	1.06	1.57	0.22	0.81	0.73	0.74	0.23	NA	1.22	1.23	0.66	0.39
QUINOLIN-2-OL (M+H)+	ME199334	1.44	1.17	0.92	0.34	1.26	0.96	1.36	0.27	0.77	0.43	0.80	0.26	NA	1.25	1.27	0.93	NA
1-METHYLNICOTINAMIDE M+	ME199271	1.64	2.08	1.19	0.69	0.73	1.28	0.89	0.74	0.96	1.26	0.72	0.72	NA	0.67	0.67	1.13	0.50
3-HYDROXYBENZALDEHYDE (M+H)+[-H2O]	ME199277	1.79	1.10	0.82	1.00	1.13	0.92	1.06	0.34	0.76	1.23	0.82	1.44	NA	1.01	1.02	0.88	0.55
4-PYRIDOXIC ACID (M+H)+	ME199278	1.98	1.77	0.71	0.48	1.13	0.86	1.05	0.63	0.65	1.00	0.82	0.85	NA	1.12	1.34	0.77	0.56
GUANINE (M+H)+	ME199304	0.81	1.22	1.01	1.19	0.78	1.31	0.25	1.77	0.63	0.76	0.86	1.35	NA	1.18	0.57	0.90	1.29
ISOVALERYLCARNITINE (*) (M+H)+	ME199307	0.38	0.42	1.56	1.59	0.79	1.98	0.74	1.95	0.55	0.69	0.85	0.68	NA	0.57	1.03	1.22	1.02
URIDINE (M+NA)+	ME199341	0.68	0.49	1.40	1.44	0.99	1.55	0.93	1.42	0.74	0.82	0.79	1.07	NA	0.85	0.77	1.12	0.73
5-HYDROXYTRYPTOPHAN (M+H)+	ME199280	0.68	0.46	1.78	0.97	0.51	1.44	0.44	0.62	1.03	1.10	1.37	1.29	NA	0.85	0.89	0.75	0.55
EPINEPHRINE (M+H)+	ME199298	0.37	0.34	1.50	1.45	1.04	1.43	0.48	0.62	0.92	0.83	1.45	1.51	NA	0.59	1.28	0.80	1.23
PROPIONYLCARNITINE (*) (M+H)+	ME199331	0.61	0.64	1.07	0.73	1.00	1.01	0.69	0.63	0.96	1.11	1.85	0.59	NA	1.14	2.08	1.01	0.67
CREATINE (M+H)+	ME199292	0.63	0.55	0.63	0.50	0.94	0.58	0.75	0.50	1.22	1.51	1.29	1.29	NA	1.39	1.42	1.33	1.40
SARCOSINE (M+H)+	ME199335	0.63	0.62	0.71	0.59	0.92	0.67	0.76	0.57	1.15	1.49	1.17	1.25	NA	1.35	1.44	1.29	1.32
CARNITINE (M+H)+	ME199286	0.80	0.96	0.94	1.15	0.54	0.85	0.52	1.27	0.84	0.82	1.34	0.83	NA	0.74	1.51	1.16	1.98
GLUCOSE (2M+NA)+	ME199299	0.54	0.51	0.93	1.21	0.57	0.79	0.66	0.86	0.91	1.23	1.21	1.37	NA	1.10	1.54	0.98	1.51
GLUCOSE (M+NA)+	ME199300	0.52	0.54	1.10	1.30	0.66	0.87	0.62	0.87	0.82	1.25	1.25	1.38	NA	0.94	1.52	1.03	1.61
18:0 LYSO-PE (M+H)+	ME199274	0.31	0.68	1.26	0.95	0.92	1.63	0.91	0.98	1.34	0.73	0.69	0.86	NA	1.24	0.87	0.93	1.08
N-ACETYL-D-TRYPTOPHAN (M+H)+	ME199315	1.02	1.13	0.82	0.64	1.15	1.02	1.43	0.75	0.93	1.17	0.64	0.61	NA	1.39	1.38	0.98	0.96
N-ACETYL-D-TRYPTOPHAN (M+NA)+	ME199316	1.06	1.18	0.85	0.64	1.16	1.10	1.47	0.75	0.85	1.13	0.65	0.63	NA	1.17	1.45	1.01	0.95
CITRIC ACID (M+NA)+	ME199291	0.83	1.38	0.99	1.20	1.00	1.12	1.10	1.07	0.74	1.06	0.75	0.80	NA	0.88	1.36	0.93	0.96
METHYL BETA-D-GALACTOSIDE (M+NA)+	ME199313	1.06	1.26	0.73	0.81	0.90	0.80	0.91	0.93	0.89	1.55	0.80	0.80	NA	1.01	1.56	0.72	1.11
N-ACETYL-DL-SERINE (M+H)+[-H2O]	ME199317	1.05	0.88	1.08	1.18	1.00	0.82	1.18	0.75	1.08	1.03	1.26	0.85	NA	1.22	1.00	0.68	0.84
PROGESTERONE (M+H)+	ME199328	0.74	0.92	1.09	1.03	0.87	0.96	1.33	1.01	0.88	0.86	1.28	0.82	NA	1.63	0.91	0.73	0.83
CHOLESTEROL (M+H)+[-H2O]	ME199287	1.42	1.34	0.82	0.94	0.82	0.93	0.93	0.90	0.91	1.14	1.24	0.99	NA	0.90	0.94	0.93	0.84
16:0 LYSO PC (M+NA)+	ME199273	0.96	0.99	0.94	0.86	1.13	0.89	1.19	0.90	0.94	1.12	0.88	0.98	NA	0.96	1.04	1.09	1.18
SUBERIC ACID (M+NA)+	ME199336	1.10	1.24	0.87	0.95	1.29	1.03	1.03	0.82	1.06	0.95	0.96	0.91	NA	0.91	0.89	1.05	0.84
AZELAIC ACID (M+H)+[-H2O]	ME199282	1.13	1.06	0.94	0.79	1.41	1.04	1.09	0.75	0.96	1.31	0.98	0.88	NA	1.07	0.87	0.85	0.74
AZELAIC ACID (M+NA)+	ME199283	1.09	1.26	0.87	0.82	1.37	0.98	1.17	0.81	0.99	1.34	0.89	0.84	NA	1.00	0.93	0.80	0.85
URIC ACID (M+H)+	ME199340	0.91	0.71	0.74	1.11	1.20	0.90	1.01	1.03	0.91	0.87	0.90	0.65	NA	1.15	1.23	1.29	1.29
LEUCINE (M+H)+	ME199310	0.68	1.09	0.91	1.18	1.19	0.83	0.99	0.81	1.05	1.15	0.96	1.00	NA	1.32	0.64	1.15	1.02
BIS(2-ETHYLHEXYL)PHTHALIC ACID (M+H)+	ME199284	0.74	1.00	0.85	0.97	1.15	1.06	1.04	1.15	1.31	0.84	0.73	0.83	NA	1.10	0.80	1.06	1.36
ELAIDIC ACID (M+H)+	ME199296	0.67	0.88	1.06	0.97	1.27	1.06	1.08	1.11	1.20	1.03	0.74	0.81	NA	1.20	0.98	0.94	0.96
20:0 LYSO PC (M+NA)+	ME199276	0.77	1.09	0.84	1.12	1.05	1.05	0.89	1.25	0.60	1.36	0.92	1.21	NA	0.61	0.91	0.80	1.22
ORNITHINE (M+H)+	ME199324	0.86	0.90	1.09	0.64	0.88	1.07	0.68	0.68	1.12	0.86	1.16	1.36	NA	1.44	1.25	0.93	0.74
CHOLINE M+	ME199290	0.63	0.64	1.02	1.26	0.55	1.11	0.72	1.12	1.06	0.93	1.49	1.21	NA	1.17	1.03	0.90	1.19
LYSINE (M+H)+	ME199311	0.62	0.67	1.34	0.96	0.69	1.33	0.76	0.99	1.19	0.82	1.47	0.96	NA	0.86	0.94	1.15	1.03
LYSINE (M+NA)+	ME199312	0.57	0.63	1.29	1.10	0.53	1.22	0.54	1.13	1.09	0.78	1.67	1.01	NA	0.81	0.99	1.16	1.16
TRYPTOPHAN (M+NA)+	ME199338	0.88	1.01	1.09	0.88	0.90	1.14	1.02	0.95	0.93	0.86	1.17	0.92	NA	0.81	1.24	1.15	1.02
EPIBRASSINOLIDE [ISTD] (M+NA)+	ME199297	0.96	1.11	1.19	1.14	0.82	1.15	0.93	1.13	0.79	1.01	1.06	0.99	NA	0.68	1.04	1.08	1.01
L-TRYPTOPHAN-15N2 [ISTD] (M+H)+	ME199308	0.88	1.02	1.20	1.05	1.07	1.22	0.96	1.00	0.96	0.98	0.92	0.91	NA	0.90	1.01	0.90	1.00
ISOLEUCINE (M+H)+	ME199306	0.83	0.90	0.97	0.89	0.93	1.12	1.00	1.01	1.19	0.92	1.19	0.97	NA	1.06	0.94	1.05	0.93
PROLINE (M+H)+	ME199329	0.78	0.84	1.06	1.12	0.78	1.00	0.76	1.06	1.09	0.98	1.13	1.12	NA	1.06	1.24	0.97	1.05
TYROSINE (M+H)+	ME199339	0.65	0.77	1.19	0.96	0.71	1.25	0.85	1.13	0.97	0.93	1.12	1.03	NA	1.13	1.15	1.08	1.07
5-AMINOPENTANOIC ACID (M+H)+	ME199279	1.09	0.96	1.16	1.19	0.70	0.76	0.61	1.04	0.84	1.04	1.56	1.32	NA	0.86	0.82	0.94	1.14
PYRIDOXAL (M+H)+[-H2O]	ME199333	0.93	0.92	1.11	1.08	0.69	1.11	0.70	1.07	0.93	0.70	1.43	1.14	NA	0.88	1.00	1.05	1.11
VALINE (M+H)+	ME199343	1.01	0.95	0.90	1.04	0.83	0.90	0.63	0.95	0.95	0.95	1.21	1.11	NA	1.09	1.12	1.05	1.34
PANTOTHENIC ACID (M+NA)+	ME199325	1.01	0.93	1.30	0.59	1.12	1.14	0.95	0.75	1.13	0.67	1.87	0.52	NA	0.78	1.16	1.05	0.57
N-ACETYL-L-PHENYLALANINE (M+H)+	ME199318	1.33	1.28	1.01	0.74	0.73	1.39	0.89	1.11	0.68	0.57	1.92	1.01	NA	0.67	0.88	0.91	0.63
N-ACETYL-L-PHENYLALANINE (M+NA)+	ME199319	1.18	1.38	1.08	0.71	0.88	1.58	0.97	1.14	0.75	0.53	1.49	0.76	NA	0.81	0.97	0.92	0.60
PROLINE (M+NA)+	ME199330	1.46	1.05	1.16	0.90	1.17	1.36	1.40	1.04	0.59	0.36	0.87	0.49	NA	0.70	0.83	0.81	0.60
UROCANIC ACID (M+H)+	ME199342	1.32	0.84	0.72	0.97	1.70	0.90	1.26	1.05	0.84	0.70	1.16	0.95	NA	0.66	0.83	1.01	1.09
1-METHYLADENOSINE (M+H)+	ME199270	0.13	NA	0.92	1.15	0.51	1.12	0.90	0.77	1.08	3.31	0.90	1.08	NA	0.72	1.12	0.81	0.89
PROSTAGLANDIN E2 (M+H)+	ME199332	0.75	0.55	1.13	0.33	2.31	1.53	0.62	0.24	2.28	2.27	0.81	1.02	NA	0.33	0.96	0.30	0.34
OLEOYL-GLYCEROL (M+NA)+	ME199323	0.15	0.04	0.48	0.35	0.32	0.30	5.58	0.12	1.72	0.16	0.17	0.10	NA	1.62	0.07	4.49	0.16
PIPECOLIC ACID (M+H)+	ME199327	0.57	0.58	0.18	0.18	3.71	0.23	6.34	0.21	0.24	0.24	0.17	0.25	NA	0.28	0.23	2.50	1.77

Factors:

F1	Genotype:Dwarf \| Sex:F \| Strain:Snell
F2	Genotype:Dwarf \| Sex:M \| Strain:Snell
F3	Genotype:Het \| Sex:F \| Strain:PappA
F4	Genotype:Het \| Sex:M \| Strain:PappA
F5	Genotype:KO \| Sex:F \| Strain:GHRKO Global
F6	Genotype:KO \| Sex:F \| Strain:PappA
F7	Genotype:KO \| Sex:M \| Strain:GHRKO Global
F8	Genotype:KO \| Sex:M \| Strain:PappA
F9	Genotype:Neg \| Sex:F \| Strain:Liver GHRKO
F10	Genotype:Neg \| Sex:M \| Strain:Liver GHRKO
F11	Genotype:Normal \| Sex:F \| Strain:Snell
F12	Genotype:Normal \| Sex:M \| Strain:Snell
F13	Genotype:Pooled plasma \| Sex:Pooled plasma \| Strain:Pooled plasma
F14	Genotype:Pos \| Sex:F \| Strain:Liver GHRKO
F15	Genotype:Pos \| Sex:M \| Strain:Liver GHRKO
F16	Genotype:WT \| Sex:F \| Strain:GHRKO Global
F17	Genotype:WT \| Sex:M \| Strain:GHRKO Global

Data matrix