Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Statin Immuno-Metabolomics in Asthma (part I) (Study ST000843)

Reversed phase NEGATIVE ION MODE (Analysis AN001364)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15	F16	F17	F18
5-KETE	ME224406	0.30	0.22	0.52	1.90	0.80	0.51	0.55	0.17	1.82	11.17	0.25	0.35	0.08	0.06	0.06	0.06	0.21	0.14
12(13)-Ep-9-KODE	ME224397	0.18	0.24	0.18	7.72	1.25	0.35	0.13	0.25	1.86	1.94	0.32	0.23	0.07	0.08	0.06	0.14	0.13	0.07
13-KODE	ME224404	0.27	0.14	0.17	6.59	0.88	0.25	0.15	0.08	1.16	6.09	0.12	0.14	0.09	0.03	0.06	0.10	0.07	0.10
9-KODE	ME224405	0.30	0.18	0.25	6.65	0.89	0.24	0.23	0.13	1.19	5.20	0.19	0.15	0.13	0.08	0.11	0.16	0.14	0.15
PGD2	ME224371	0.43	0.63	0.85	0.62	0.39	0.25	1.10	1.94	1.74	1.37	3.26	1.76	0.83	1.22	1.55	0.51	1.37	0.78
5_15-DiHETE	ME224410	0.04	0.96	1.82	0.16	1.43	1.10	0.07	1.33	1.47	0.02	0.96	1.55	NA	NA	NA	NA	NA	NA
PGE1	ME224369	0.70	1.46	1.12	0.46	1.51	0.57	0.62	1.36	1.87	0.53	1.63	5.14	0.26	0.51	0.53	0.22	0.27	0.19
PGE2	ME224370	0.90	1.26	1.35	0.71	1.62	0.55	1.25	0.76	1.44	1.49	1.24	2.94	0.45	0.66	0.61	0.32	0.38	0.23
15-KETE	ME224432	0.67	0.14	0.32	1.26	0.48	0.28	0.17	0.03	0.52	6.95	0.07	0.15	NA	NA	NA	NA	NA	NA
8(9)-EpETrE	ME224402	1.26	0.57	0.49	2.18	0.81	1.05	1.60	0.23	2.78	5.25	0.59	0.16	0.31	0.15	0.16	0.23	0.19	0.25
15-HETE	ME224389	1.49	0.50	0.62	4.43	1.10	0.59	1.28	0.22	1.89	5.02	0.32	0.48	0.22	0.19	0.12	0.20	0.10	0.10
9(10)-EpODE	ME224399	0.75	0.42	0.53	3.74	0.82	0.32	0.68	0.64	0.91	5.99	0.63	0.52	0.31	0.07	0.13	0.19	0.17	0.19
LTB4	ME224376	1.13	0.31	2.38	1.34	0.21	1.31	5.75	0.41	0.89	2.01	0.73	0.59	0.36	0.17	0.19	0.14	0.75	0.31
LTB5	ME224409	1.32	0.49	1.70	1.07	0.47	1.23	2.96	0.66	0.44	1.12	0.63	0.49	NA	NA	NA	NA	NA	NA
5-HETE	ME224392	0.71	0.48	2.88	1.28	0.41	1.03	3.22	0.22	2.07	2.68	0.78	0.49	0.37	0.15	0.16	0.13	0.46	0.17
6-trans-LTB4	ME224375	0.65	0.34	3.71	1.36	0.33	1.06	1.76	0.16	1.07	1.15	0.39	0.22	NA	NA	NA	NA	0.34	NA
20-HETE	ME224388	3.23	0.25	0.75	0.53	0.62	1.06	NA	NA	NA	NA	NA	NA	1.01	1.29	0.36	2.40	0.40	0.76
Lipoxin A4	ME224374	0.67	1.08	0.94	0.72	0.96	1.01	NA	NA	NA	NA	NA	NA	0.97	1.12	0.81	1.26	0.99	1.28
12(13)-EpOME	ME224395	1.36	0.88	0.90	1.61	0.97	0.73	0.78	0.30	0.65	1.69	0.35	0.44	1.31	0.88	1.00	1.60	1.09	1.20
9(10)-EpOME	ME224396	1.38	0.76	0.85	1.91	1.02	0.71	0.78	0.25	0.69	1.94	0.37	0.38	1.26	0.81	0.94	1.39	1.05	1.15
13-HOTE	ME224387	0.46	0.36	3.80	3.43	1.27	0.63	0.76	0.37	1.09	1.04	0.44	0.21	0.45	0.10	0.04	0.27	0.03	0.02
15(16)-EpODE	ME224427	0.64	0.36	0.96	0.82	0.67	0.82	0.61	0.49	0.51	3.83	0.26	NA	NA	NA	NA	NA	NA	NA
15-Keto PGE2	ME224407	1.17	0.48	0.36	1.70	1.27	0.39	1.05	0.69	0.12	3.68	0.81	0.04	NA	NA	NA	NA	NA	NA
12-HETE	ME224390	1.26	0.98	0.84	2.10	1.82	0.18	1.79	0.14	2.38	2.59	0.70	0.54	0.33	0.33	0.35	0.54	0.25	0.37
14-HDoHE	ME224393	1.79	1.03	0.84	2.49	1.32	0.20	2.65	0.11	1.95	2.19	0.55	0.58	0.48	0.33	0.25	0.58	0.14	0.31
11_12-DiHETrE	ME224383	1.26	0.68	1.04	2.45	0.57	0.38	2.60	0.71	1.61	3.28	0.41	0.64	0.39	0.74	0.25	0.07	0.26	0.24
11(12)-EpETrE	ME224401	1.35	0.93	0.65	1.89	0.69	0.74	2.04	0.70	2.26	3.90	1.02	0.53	0.51	0.24	0.20	0.36	0.25	0.22
14(15)-EpETrE	ME224400	1.47	0.74	0.86	1.99	0.77	0.75	2.09	0.34	1.62	3.92	0.52	0.68	0.69	0.36	0.28	0.47	0.40	0.36
19(20)-EpDPE	ME224403	1.47	0.79	0.71	1.62	0.73	1.99	0.43	1.10	1.24	3.01	1.00	0.50	0.59	0.23	0.04	0.33	NA	0.05
PGF2a	ME224372	0.98	1.02	2.14	1.47	0.84	0.99	1.54	0.25	0.85	2.39	0.51	1.11	0.54	0.45	0.63	0.49	0.39	0.36
12(13)-EpODE	ME224398	1.06	0.58	0.97	2.53	1.14	0.78	0.94	2.12	0.70	2.51	0.70	NA	0.16	0.45	0.22	0.27	0.34	0.20
15_16-DiHODE	ME224380	1.41	0.63	1.02	2.04	0.75	1.00	1.20	0.57	0.54	3.74	0.68	0.48	0.61	0.10	0.13	0.41	0.69	0.25
12_13-DiHOME	ME224378	1.39	1.04	0.77	1.98	1.17	0.59	1.59	1.07	0.48	3.07	1.14	0.41	0.49	0.42	0.44	0.67	0.49	0.44
9_10-DiHOME	ME224379	1.39	1.03	0.85	1.95	1.06	0.60	1.43	1.01	0.55	2.83	1.04	0.40	0.60	0.50	0.54	0.82	0.52	0.54
19_20-DiHDoPA	ME224384	1.15	0.72	0.71	1.37	1.78	0.62	1.23	1.11	1.43	2.73	1.42	0.40	0.58	0.14	0.30	0.46	0.35	0.26
14_15-DiHETrE	ME224382	1.05	0.93	1.53	1.69	1.17	0.17	1.03	1.33	0.87	2.00	1.07	0.90	0.74	0.60	0.39	0.61	0.63	0.39
SUM-TriHOME	ME224377	0.99	1.02	1.37	1.93	1.11	0.80	1.65	1.29	1.57	2.24	1.18	0.96	0.21	0.20	0.17	0.23	0.17	0.19
TXB2	ME224368	1.11	0.81	1.12	1.29	2.59	0.68	1.31	0.45	1.44	1.29	0.79	0.52	0.58	0.29	0.76	0.31	0.83	0.35
8_15-DiHETE	ME224411	0.92	0.79	0.68	2.32	0.91	1.27	0.40	1.19	0.92	1.14	0.59	1.05	NA	NA	NA	NA	NA	NA
15-deoxy PGJ2	ME224408	1.10	0.84	1.11	1.13	1.06	1.21	0.67	0.91	0.99	1.14	0.84	0.87	NA	NA	NA	NA	NA	NA
9_10-e-DiHO	ME224413	1.05	1.01	1.39	1.41	0.90	0.96	0.86	0.98	0.62	1.35	0.64	0.70	NA	NA	NA	NA	NA	NA
9_10-EpO	ME224426	1.18	1.17	1.34	1.12	0.86	1.13	0.84	1.09	0.67	1.15	0.50	0.93	NA	NA	NA	NA	NA	NA
9_10-DiHODE	ME224381	1.51	0.67	0.99	2.64	1.40	0.71	1.16	0.71	0.21	2.52	0.74	0.10	0.15	0.05	NA	0.10	0.05	NA
12-HEPE	ME224422	1.59	0.70	0.52	2.25	1.56	0.21	1.74	0.13	1.13	1.66	0.35	0.41	NA	NA	NA	NA	NA	NA
15-HEPE	ME224421	0.86	0.40	0.82	2.23	1.02	0.29	1.33	0.27	1.31	2.11	0.57	0.20	NA	NA	NA	NA	NA	NA
17-HDoHE	ME224425	0.68	0.95	0.30	3.30	1.08	0.57	1.08	0.18	0.75	0.94	0.46	0.54	NA	NA	NA	NA	NA	NA
9-HETE	ME224420	0.66	0.46	1.27	2.99	0.90	0.71	0.34	0.26	0.92	1.96	0.57	0.43	NA	NA	NA	NA	NA	NA
9-HOTE	ME224419	0.60	0.49	1.56	3.78	0.88	0.53	0.34	0.44	0.92	1.29	0.22	0.40	NA	NA	NA	NA	NA	NA
6-keto PGF1a	ME224367	0.67	0.66	0.49	4.39	2.66	0.52	0.33	0.18	0.81	1.47	0.85	0.40	0.22	0.20	0.36	0.11	0.37	0.41
4-HDoHE	ME224394	1.23	0.44	1.47	2.71	1.36	1.03	0.80	0.29	2.12	2.56	0.65	0.24	0.11	0.08	0.04	0.05	0.14	0.01
8-HETE	ME224391	0.53	0.22	0.89	4.79	1.07	1.10	1.19	0.26	1.90	2.74	0.31	0.27	0.14	0.14	0.03	0.11	0.05	0.03
11-HETE	ME224373	0.76	0.61	0.90	3.39	1.18	0.45	1.24	0.56	1.66	3.76	0.59	1.07	0.26	0.22	0.20	0.18	0.22	0.20
13-HODE	ME224385	0.73	0.57	1.29	3.62	1.16	0.43	1.05	0.37	1.72	2.96	0.52	0.55	0.31	0.28	0.27	0.39	0.25	0.29
9-HODE	ME224386	0.76	0.52	0.99	4.17	1.15	0.47	0.87	0.47	1.55	3.11	0.58	0.57	0.26	0.19	0.23	0.31	0.24	0.23

Factors:

F1	Treatment:Control \| Lung:Left Lung \| Time point (day):-
F2	Treatment:Control \| Lung:Left Lung \| Time point (day):12
F3	Treatment:Control \| Lung:Left Lung \| Time point (day):8
F4	Treatment:Control \| Lung:Right Lung \| Time point (day):-
F5	Treatment:Control \| Lung:Right Lung \| Time point (day):12
F6	Treatment:Control \| Lung:Right Lung \| Time point (day):8
F7	Treatment:Pravastatin \| Lung:Left Lung \| Time point (day):-
F8	Treatment:Pravastatin \| Lung:Left Lung \| Time point (day):12
F9	Treatment:Pravastatin \| Lung:Left Lung \| Time point (day):8
F10	Treatment:Pravastatin \| Lung:Right Lung \| Time point (day):-
F11	Treatment:Pravastatin \| Lung:Right Lung \| Time point (day):12
F12	Treatment:Pravastatin \| Lung:Right Lung \| Time point (day):8
F13	Treatment:Simvastatin \| Lung:Left Lung \| Time point (day):-
F14	Treatment:Simvastatin \| Lung:Left Lung \| Time point (day):12
F15	Treatment:Simvastatin \| Lung:Left Lung \| Time point (day):8
F16	Treatment:Simvastatin \| Lung:Right Lung \| Time point (day):-
F17	Treatment:Simvastatin \| Lung:Right Lung \| Time point (day):12
F18	Treatment:Simvastatin \| Lung:Right Lung \| Time point (day):8

Data matrix