Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Diet, genetics and gut microbiome drive dynamic changes in plasma metabolites [cecal] (Study ST000880)

Reversed phase NEGATIVE ION MODE (Analysis AN001435)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12
Glycocholic Acid	ME227362	0.26	0.55	0.02	0.29	0.26	0.53	0.71	5.27	2.58	0.04	0.22	0.16
Taurodeoxycholic acid	ME227365	0.46	0.01	0.03	0.00	0.00	0.00	1.78	2.94	4.29	0.00	0.00	0.00
Taurolithocholic acid	ME227368	0.64	0.06	0.06	0.01	0.00	0.01	1.58	1.90	4.71	0.00	0.07	0.01
Taurochenodeoxycholic acid	ME227366	0.33	0.06	0.03	1.04	0.63	3.59	1.08	0.69	0.58	0.44	0.97	2.33
PGE2-d4 (Internal Standard)	ME227333	0.92	0.95	0.99	1.05	1.13	1.08	0.92	0.94	0.83	1.03	1.11	1.04
Stearic acid	ME227338	0.70	0.67	0.86	1.22	1.34	1.04	1.11	0.83	1.08	1.08	1.10	0.95
Taurocholic acid	ME227364	0.10	0.01	0.00	2.17	1.43	1.08	2.08	0.45	0.38	0.96	2.16	0.93
Tauro-beta-muricholic acid	ME227371	0.09	0.04	0.00	1.77	0.88	1.93	1.26	0.46	0.68	1.03	1.34	2.27
Taurohyodeoxycholate/Tauroursodeoxycholate	ME227367	0.45	0.10	0.02	1.28	0.89	1.56	2.13	1.34	1.11	0.53	1.10	1.26
Eicosapentaenoic acid	ME227344	3.23	4.12	2.71	0.13	0.17	0.33	0.21	0.22	0.68	0.10	0.18	0.35
DHA	ME227347	1.85	2.66	2.17	0.28	0.36	0.91	0.38	0.55	1.73	0.15	0.37	0.87
DPA	ME227346	2.21	3.06	2.09	0.14	0.18	0.56	0.56	0.47	2.10	0.08	0.17	0.65
PGD2	ME227355	NA	1.15	2.69	0.44	0.45	0.30	0.27	1.59	1.87	NA	0.72	0.48
Glycodeoxycholic acid	ME227363	0.39	0.11	0.10	NA	NA	0.02	2.33	2.17	1.25	NA	0.02	NA
PGE1	ME227356	0.40	0.87	0.16	1.55	0.56	1.07	2.00	1.01	1.12	NA	0.08	NA
Chenodeoxycholic Acid	ME227361	0.83	3.21	0.43	0.01	0.07	0.56	1.24	0.99	2.33	0.01	0.01	NA
Cholic acid	ME227359	0.87	2.30	0.11	0.33	0.77	0.58	1.70	2.30	2.56	0.00	0.01	0.00
Alpha-muricholic acid	ME227369	2.82	0.73	1.03	0.03	0.03	0.03	0.79	1.28	2.77	0.00	NA	0.00
Beta-muricholic acid	ME227370	2.31	1.31	1.08	0.07	0.36	0.09	1.44	2.06	3.26	0.01	0.02	0.03
Deoxycholic acid	ME227360	1.80	1.69	1.22	0.00	0.00	0.00	1.55	2.85	2.94	0.00	0.00	0.00
Lipoxin A4	ME227354	2.10	0.99	1.52	1.45	0.43	0.33	0.52	0.86	1.83	NA	0.29	0.26
Lithocholic acid	ME227358	1.26	1.24	1.60	NA	NA	0.00	0.36	0.58	1.61	NA	NA	0.00
Myristoleic acid	ME227335	2.86	0.59	0.65	0.36	0.13	0.35	3.20	1.33	1.54	0.12	0.35	0.44
Palmitoleic acid	ME227337	1.97	0.50	0.62	0.59	0.20	0.53	2.87	1.65	1.66	0.20	0.53	0.58
5-HETE	ME227348	2.10	1.63	1.48	0.22	0.26	0.47	0.97	1.07	2.17	0.22	0.48	0.85
Gamma-linolenic acid	ME227341	2.29	1.44	1.03	0.34	0.21	0.47	2.11	1.18	1.78	0.16	0.36	0.64
Linoleic acid	ME227340	1.77	1.10	0.95	0.48	0.42	0.65	2.03	1.28	1.64	0.32	0.54	0.79
Myristic acid	ME227334	2.02	0.92	0.96	0.55	0.43	0.58	2.16	1.23	1.58	0.35	0.52	0.69
Bishomo-gamma-linolenic acid	ME227342	1.15	1.25	0.83	0.58	0.48	0.97	1.49	1.21	2.13	0.28	0.51	1.08
Oleic acid	ME227339	1.43	0.85	0.89	0.66	0.56	0.84	1.88	1.19	1.66	0.45	0.63	0.94
Palmitic acid	ME227336	1.47	0.87	0.94	0.76	0.74	0.78	1.69	1.09	1.53	0.58	0.71	0.82
Sphingosine-1-phosphate	ME227357	NA	0.36	1.04	0.42	NA	0.81	NA	NA	2.87	NA	1.20	0.73
11-HETE	ME227349	0.49	1.46	0.77	NA	0.49	1.24	0.52	0.40	3.51	0.54	0.75	0.99
Adrenic Acid	ME227345	1.03	1.09	1.09	0.34	0.39	1.27	1.05	0.87	2.88	0.20	0.45	1.35
Arachidonic acid	ME227343	0.81	0.70	0.66	0.47	0.69	1.47	0.91	0.98	2.54	0.41	0.70	1.56
9-HETE	ME227352	1.61	1.04	0.98	0.11	0.37	0.75	0.62	0.62	2.71	0.20	0.52	1.01
12S-HETE	ME227350	1.46	1.12	1.01	0.25	0.58	0.92	0.89	0.94	2.43	0.42	1.22	0.75
15S-HETE	ME227351	1.43	1.23	0.88	0.33	0.63	0.94	0.75	0.90	2.29	0.60	0.96	0.86

Factors:

F1	Diet:Chow \| Treatment:none \| Strain:129Jax
F2	Diet:Chow \| Treatment:none \| Strain:129Tac
F3	Diet:Chow \| Treatment:none \| Strain:B6Jax
F4	Diet:HFD \| Treatment:metronidazole \| Strain:129Jax
F5	Diet:HFD \| Treatment:metronidazole \| Strain:129Tac
F6	Diet:HFD \| Treatment:metronidazole \| Strain:B6Jax
F7	Diet:HFD \| Treatment:placebo \| Strain:129Jax
F8	Diet:HFD \| Treatment:placebo \| Strain:129Tac
F9	Diet:HFD \| Treatment:placebo \| Strain:B6Jax
F10	Diet:HFD \| Treatment:vancomycin \| Strain:129Jax
F11	Diet:HFD \| Treatment:vancomycin \| Strain:129Tac
F12	Diet:HFD \| Treatment:vancomycin \| Strain:B6Jax

Data matrix