Clustering data with hclust algorithm for Development of a weaned pig model of enterotoxigenic E.coli-induced environmental enteropathy (Study ST001041)
GC POSITIVE ION MODE (Analysis AN001706)Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
gluconic acid | ME252106 | 0.03 | 7.14 | 0.09 | 0.69 | 0.03 | 0.27 | 0.04 | 3.08 | 0.11 | 0.13 | 0.09 | 0.05 |
mannonic acid NIST | ME252054 | 0.07 | 7.92 | 0.22 | 1.45 | 0.07 | 0.69 | 0.10 | 0.22 | 0.48 | 0.24 | 0.22 | 0.10 |
ethanol phosphate NIST | ME252114 | 0.02 | 0.20 | 0.04 | 0.34 | 0.09 | 0.10 | 0.42 | 6.17 | 3.44 | 0.53 | 0.14 | 0.26 |
pinitol | ME252014 | 0.01 | 2.69 | 0.07 | 0.08 | 0.05 | 0.09 | 0.29 | 0.13 | 2.11 | 6.05 | 0.06 | 0.13 |
fructose | ME252112 | 0.10 | 2.70 | 0.27 | 0.33 | 0.17 | 0.17 | 0.15 | 0.21 | 0.47 | 6.93 | 0.11 | 0.17 |
tagatose | ME251996 | 0.22 | 0.80 | 0.19 | 1.17 | 0.19 | 0.38 | 0.28 | 0.34 | 1.13 | 6.81 | 0.12 | 0.19 |
glycerol-3-galactoside | ME252097 | 0.58 | 1.62 | 0.26 | 0.60 | 0.41 | 0.49 | 0.28 | 0.68 | 0.45 | 6.08 | 0.23 | 0.22 |
isomaltose | ME252075 | 0.10 | 1.63 | 0.12 | 0.49 | 0.10 | 0.61 | 0.20 | 0.69 | 0.42 | 6.76 | 0.47 | 0.19 |
citric acid | ME252125 | 0.51 | 1.03 | 1.38 | 0.18 | 1.95 | 0.26 | 0.30 | 0.53 | 0.67 | 4.78 | 0.17 | 0.12 |
daidzein | ME252120 | 0.09 | 2.25 | 0.14 | 0.69 | 0.19 | 0.68 | 0.75 | 0.84 | 1.07 | 3.85 | 0.66 | 0.55 |
orotic acid | ME252030 | 0.23 | 2.54 | 0.45 | 0.95 | 0.75 | 0.52 | 1.07 | 0.49 | 0.82 | 3.19 | 0.50 | 0.29 |
conduritol-beta-epoxide | ME252124 | 0.03 | 2.41 | 0.05 | 0.23 | 0.08 | 0.25 | 0.89 | 0.52 | 1.78 | 4.77 | 0.21 | 0.54 |
sophorose | ME252000 | 0.45 | 2.02 | 0.19 | 0.48 | 0.26 | 0.72 | 0.36 | 1.13 | 0.71 | 4.84 | 0.28 | 0.43 |
inosine | ME252079 | 7.65 | 0.79 | 0.50 | 0.79 | 0.49 | 1.94 | 0.38 | 0.33 | 0.33 | 0.15 | 0.17 | 0.15 |
mannitol | ME252055 | 4.32 | 0.12 | 0.76 | 0.20 | 0.03 | 2.49 | 1.67 | 2.25 | 0.37 | 0.26 | 0.27 | 0.10 |
asparagine | ME252138 | 3.81 | 1.23 | 0.32 | 1.13 | 0.52 | 1.20 | 0.79 | 0.82 | 0.99 | 0.86 | 0.36 | 0.67 |
elaidic acid | ME252116 | 4.85 | 0.70 | 0.12 | 0.73 | 0.43 | 0.55 | 0.82 | 0.96 | 0.56 | 1.03 | 0.81 | 1.39 |
xylose | ME251974 | 0.02 | 4.51 | 0.06 | 1.53 | 0.06 | 0.58 | 0.25 | 0.38 | 1.90 | 1.87 | 0.27 | 0.32 |
1,3-diaminopropane | ME252191 | 0.07 | 3.40 | 0.26 | 1.43 | 0.48 | 0.42 | 0.52 | 0.80 | 1.44 | 1.62 | 0.65 | 0.67 |
creatinine | ME252123 | 0.37 | 4.13 | 0.20 | 1.65 | 0.62 | 0.20 | 0.40 | 0.43 | 1.47 | 1.21 | 0.66 | 0.50 |
1,5-anhydroglucitol | ME252190 | 0.37 | 4.24 | 0.05 | 0.46 | 0.06 | 1.40 | 0.68 | 0.68 | 0.95 | 1.43 | 0.76 | 0.77 |
maltose | ME252057 | 0.30 | 4.28 | 0.64 | 1.12 | 0.11 | 0.55 | 1.10 | 0.54 | 0.55 | 1.19 | 0.66 | 0.79 |
galactose | ME252109 | 0.12 | 3.14 | 0.04 | 1.76 | 0.12 | 0.08 | 0.04 | 0.10 | 3.64 | 2.61 | 0.05 | 0.08 |
glucose | ME252104 | 0.04 | 4.11 | 0.02 | 0.54 | 0.04 | 0.09 | 0.03 | 1.09 | 2.66 | 2.94 | 0.16 | 0.04 |
gluconic acid lactone | ME252105 | 0.11 | 5.12 | 0.07 | 0.48 | 0.05 | 0.23 | 0.11 | 0.93 | 2.65 | 1.83 | 0.09 | 0.10 |
methyl O-D-galactopyranoside | ME252049 | 0.02 | 4.92 | 0.05 | 0.22 | 0.05 | 0.36 | 0.22 | 0.19 | 3.61 | 1.79 | 0.13 | 0.20 |
ribonic acid | ME252004 | 0.02 | 1.10 | 0.05 | 0.24 | 0.07 | 1.14 | 1.50 | 3.52 | 0.19 | 0.33 | 3.32 | 0.28 |
xylonic acid | ME251975 | 0.01 | 1.33 | 0.04 | 0.30 | 0.08 | 0.77 | 1.72 | 3.95 | 0.42 | 0.52 | 2.15 | 0.46 |
2^-deoxyguanosine | ME252180 | 1.97 | 0.83 | 0.20 | 1.58 | 0.12 | 0.92 | 0.47 | 1.01 | 3.13 | 0.66 | 0.54 | 0.81 |
2,8-dihydroxyquinoline | ME252183 | 0.03 | 2.21 | 0.17 | 2.44 | 0.12 | 2.64 | 1.02 | 0.82 | 0.92 | 0.30 | 0.60 | 0.49 |
chenodeoxycholic acid | ME252129 | 0.10 | 0.49 | 0.27 | 1.02 | 0.18 | 2.01 | 2.78 | 0.65 | 0.84 | 1.03 | 1.13 | 1.27 |
melezitose | ME252053 | 0.44 | 0.48 | 0.63 | 0.33 | 0.14 | 1.50 | 2.86 | 0.15 | 2.01 | 0.39 | 1.68 | 1.27 |
glyceric acid | ME252099 | 0.18 | 0.89 | 0.50 | 1.66 | 0.33 | 0.75 | 0.64 | 3.72 | 1.50 | 0.52 | 0.40 | 0.70 |
levoglucosan | ME252066 | 0.02 | 2.51 | 0.69 | 0.86 | 0.11 | 1.07 | 0.36 | 2.50 | 2.04 | 0.30 | 0.70 | 0.59 |
arabitol | ME252141 | 0.28 | 1.72 | 0.73 | 0.53 | 0.17 | 0.89 | 1.23 | 3.08 | 1.63 | 0.23 | 1.12 | 0.22 |
lyxitol | ME252061 | 0.32 | 1.94 | 0.89 | 0.65 | 0.21 | 0.99 | 1.36 | 2.70 | 1.77 | 0.24 | 0.54 | 0.22 |
adenine | ME252149 | 2.17 | 2.48 | 0.61 | 0.43 | 0.51 | 0.51 | 1.40 | 0.77 | 1.31 | 1.40 | 0.30 | 0.39 |
putrescine | ME252008 | 0.00 | 0.48 | 0.00 | 0.53 | 0.01 | 0.25 | 1.37 | 3.13 | 0.38 | 2.30 | 0.80 | 2.50 |
cytosin | ME252121 | 0.08 | 1.18 | 0.11 | 0.69 | 0.08 | 0.52 | 1.74 | 1.99 | 0.54 | 2.26 | 0.54 | 2.04 |
D-erythro-sphingosine | ME252119 | 0.16 | 0.48 | 0.25 | 0.97 | 0.26 | 0.58 | 1.24 | 1.98 | 0.73 | 2.05 | 1.12 | 1.97 |
tyramine | ME251985 | 0.07 | 0.39 | 0.35 | 0.82 | 0.00 | 0.77 | 0.51 | 0.60 | 2.64 | 2.32 | 1.74 | 1.55 |
oxalic acid | ME252029 | 0.66 | 0.45 | 0.87 | 0.16 | 1.46 | 0.22 | 1.05 | 0.78 | 0.77 | 2.20 | 1.88 | 1.40 |
3-(4-hydroxyphenyl)propionic acid | ME252169 | 0.12 | 0.41 | 0.16 | 1.15 | 0.37 | 1.30 | 0.80 | 0.56 | 0.69 | 2.10 | 2.52 | 1.61 |
phytanic acid | ME252016 | 0.40 | 0.49 | 0.62 | 0.74 | 1.21 | 0.60 | 0.72 | 0.87 | 0.80 | 1.21 | 3.20 | 0.99 |
glucose-6-phosphate | ME252103 | 0.22 | 1.00 | 0.71 | 1.59 | 0.64 | 1.30 | 0.69 | 0.90 | 1.88 | 2.32 | 0.36 | 0.20 |
taurine | ME251995 | 0.99 | 0.91 | 0.64 | 1.76 | 0.69 | 2.21 | 0.17 | 0.71 | 1.46 | 1.79 | 0.31 | 0.34 |
2-ketoadipic acid | ME252174 | 0.86 | 0.71 | 0.41 | 0.61 | 1.01 | 1.83 | 1.27 | 0.77 | 0.81 | 2.45 | 0.50 | 0.73 |
cellobiose | ME252130 | 0.81 | 1.03 | 0.36 | 0.94 | 0.59 | 2.18 | 0.49 | 0.96 | 0.97 | 3.05 | 0.24 | 0.34 |
lactose | ME252069 | 0.43 | 0.63 | 0.59 | 0.69 | 0.47 | 3.07 | 0.86 | 1.04 | 0.85 | 2.85 | 0.20 | 0.19 |
lithocholic acid | ME252063 | 0.48 | 0.52 | 1.44 | 0.96 | 0.80 | 2.69 | 0.61 | 1.44 | 0.99 | 0.43 | 0.94 | 0.55 |
maltotriose | ME252056 | 1.17 | 1.17 | 0.88 | 1.29 | 1.16 | 2.49 | 1.56 | 0.53 | 0.64 | 0.63 | 0.23 | 0.29 |
3-hydroxybutyric acid | ME252162 | 0.19 | 0.77 | 0.15 | 0.77 | 0.32 | 2.23 | 1.02 | 2.74 | 1.04 | 0.67 | 1.27 | 0.64 |
glutamine | ME252101 | 0.83 | 1.01 | 0.10 | 0.28 | 0.26 | 3.13 | 0.38 | 1.79 | 1.64 | 0.50 | 0.60 | 1.43 |
N-acetylgalactosamine | ME252044 | 0.07 | 2.06 | 1.14 | 2.06 | 0.18 | 0.30 | 0.28 | 2.50 | 0.68 | 2.20 | 0.11 | 0.18 |
n-acetyl-d-hexosamine | ME252045 | 0.12 | 1.59 | 0.18 | 2.35 | 0.58 | 0.59 | 0.43 | 0.55 | 2.35 | 0.74 | 1.32 | 0.98 |
ketohexose | ME252072 | 0.24 | 1.74 | 0.14 | 2.53 | 0.21 | 0.80 | 0.77 | 0.68 | 2.14 | 1.42 | 0.53 | 0.60 |
xylulose NIST | ME251973 | 0.09 | 2.66 | 0.25 | 2.81 | 0.12 | 0.59 | 0.39 | 0.60 | 1.83 | 1.75 | 0.31 | 0.38 |
erythritol | ME252115 | 0.32 | 2.34 | 1.75 | 0.61 | 0.29 | 0.75 | 1.49 | 1.15 | 0.69 | 1.15 | 0.69 | 0.59 |
pantothenic acid | ME252025 | 0.51 | 3.24 | 0.45 | 0.46 | 0.60 | 0.71 | 0.88 | 1.94 | 0.65 | 0.99 | 0.76 | 0.69 |
hydrocinnamic acid | ME252086 | 0.17 | 0.77 | 0.14 | 1.30 | 0.31 | 0.74 | 1.23 | 1.18 | 1.01 | 2.36 | 1.23 | 1.36 |
myo-inositol | ME252048 | 0.17 | 1.65 | 0.13 | 1.18 | 0.18 | 0.32 | 1.57 | 1.24 | 0.70 | 2.75 | 0.69 | 1.21 |
sarcosine | ME252002 | 0.50 | 2.27 | 0.74 | 0.54 | 0.77 | 0.57 | 1.71 | 0.74 | 1.12 | 1.54 | 1.05 | 0.32 |
lactamide | ME252071 | 0.06 | 2.42 | 0.13 | 1.70 | 0.15 | 0.42 | 0.91 | 0.86 | 1.46 | 1.97 | 0.74 | 0.94 |
glycerol | ME252098 | 0.50 | 1.94 | 0.65 | 1.43 | 0.69 | 0.77 | 1.11 | 0.84 | 0.77 | 1.64 | 0.61 | 0.91 |
glucoheptulose | ME252107 | 0.22 | 2.03 | 0.30 | 1.47 | 0.38 | 0.53 | 1.34 | 1.18 | 1.07 | 1.70 | 1.04 | 0.56 |
N-acetylaspartic acid | ME252046 | 0.15 | 2.07 | 0.34 | 0.88 | 0.70 | 0.43 | 1.45 | 0.94 | 1.01 | 2.08 | 1.02 | 0.71 |
noradrenaline | ME252038 | 0.05 | 2.14 | 0.06 | 1.01 | 0.11 | 0.52 | 0.49 | 2.80 | 1.44 | 1.93 | 0.47 | 0.73 |
lyxose | ME252060 | 0.06 | 2.30 | 0.12 | 1.70 | 0.08 | 1.03 | 0.52 | 1.62 | 1.51 | 1.66 | 0.80 | 0.36 |
3,6-anhydro-D-galactose | ME252167 | 0.26 | 1.62 | 0.11 | 1.65 | 0.19 | 1.36 | 0.80 | 1.52 | 1.12 | 1.66 | 0.71 | 0.83 |
3,6-anhydro-D-glucose | ME252166 | 0.22 | 1.43 | 0.09 | 1.47 | 0.15 | 1.24 | 0.59 | 1.70 | 1.42 | 2.15 | 0.68 | 0.66 |
3-ureidopropionate | ME252158 | 0.44 | 2.47 | 1.04 | 2.26 | 0.32 | 0.55 | 0.49 | 1.36 | 1.12 | 0.77 | 0.62 | 0.42 |
ribose | ME252003 | 0.37 | 2.26 | 1.00 | 2.03 | 0.29 | 0.94 | 0.59 | 1.45 | 1.51 | 0.68 | 0.25 | 0.47 |
hexuronic acid | ME252089 | 0.04 | 2.40 | 0.06 | 1.78 | 0.03 | 0.17 | 1.46 | 1.99 | 1.61 | 1.03 | 0.98 | 0.21 |
galacturonic acid | ME252108 | 0.01 | 2.52 | 0.02 | 1.98 | 0.03 | 1.43 | 0.65 | 2.17 | 1.18 | 0.44 | 0.59 | 0.73 |
isoribose | ME252074 | 0.09 | 2.53 | 0.14 | 1.85 | 0.18 | 0.27 | 1.30 | 1.44 | 1.11 | 0.93 | 0.73 | 1.20 |
pyruvic acid | ME252007 | 0.76 | 2.34 | 0.40 | 0.85 | 0.25 | 0.52 | 1.21 | 2.12 | 1.03 | 0.78 | 0.66 | 1.03 |
6-deoxyglucose | ME252151 | 0.05 | 2.06 | 0.20 | 1.30 | 0.09 | 0.89 | 1.18 | 2.45 | 1.11 | 0.80 | 0.72 | 0.91 |
fucose | ME252111 | 0.06 | 2.10 | 0.27 | 1.67 | 0.22 | 0.97 | 1.14 | 1.83 | 1.04 | 0.88 | 0.46 | 1.12 |
2-deoxyerythritol | ME252181 | 0.36 | 0.90 | 0.77 | 0.41 | 1.66 | 0.91 | 0.97 | 2.68 | 0.84 | 0.79 | 0.71 | 0.83 |
2-methylglutaric acid | ME252172 | 0.92 | 0.51 | 0.38 | 0.33 | 2.41 | 0.42 | 1.15 | 1.21 | 0.69 | 0.73 | 2.10 | 1.14 |
octadecanol | ME252035 | 1.84 | 0.35 | 0.96 | 0.61 | 2.42 | 0.67 | 0.69 | 0.75 | 0.55 | 0.79 | 1.52 | 1.06 |
O-acetylserine | ME252036 | 0.25 | 1.19 | 0.35 | 0.96 | 3.51 | 0.52 | 1.06 | 0.93 | 0.86 | 0.71 | 0.59 | 0.88 |
4-hydroxymandelic acid | ME252155 | 1.00 | 0.83 | 0.86 | 0.71 | 2.79 | 0.95 | 0.94 | 1.15 | 0.90 | 0.39 | 1.22 | 0.26 |
pimelic acid | ME252015 | 0.56 | 0.84 | 0.42 | 0.82 | 2.29 | 1.42 | 0.95 | 1.48 | 0.93 | 0.52 | 0.86 | 0.80 |
octadecylglycerol | ME252034 | 1.05 | 0.37 | 0.18 | 0.64 | 0.48 | 0.35 | 1.13 | 2.32 | 1.07 | 1.92 | 1.70 | 0.79 |
tyrosol | ME251983 | 0.74 | 0.72 | 0.15 | 1.82 | 0.39 | 0.65 | 0.92 | 1.96 | 0.63 | 1.48 | 2.02 | 0.48 |
alpha-aminoadipic acid | ME252145 | 2.47 | 0.99 | 1.05 | 0.83 | 1.47 | 0.79 | 0.71 | 1.39 | 0.69 | 0.84 | 0.47 | 0.67 |
hexadecylglycerol NIST | ME252090 | 2.21 | 0.48 | 0.48 | 0.64 | 1.30 | 0.53 | 0.94 | 1.91 | 0.73 | 1.27 | 1.11 | 0.70 |
cis-gondoic acid | ME252127 | 0.52 | 0.66 | 1.65 | 0.92 | 1.43 | 1.01 | 0.78 | 1.04 | 1.22 | 0.47 | 0.66 | 1.51 |
sucrose | ME251997 | 0.98 | 0.90 | 1.58 | 0.65 | 1.72 | 1.38 | 0.86 | 0.72 | 0.90 | 1.54 | 0.33 | 0.45 |
pelargonic acid | ME252023 | 1.09 | 0.61 | 1.35 | 1.06 | 1.17 | 1.82 | 1.30 | 1.18 | 0.83 | 0.60 | 0.60 | 0.41 |
proline | ME252011 | 1.05 | 1.08 | 1.75 | 0.97 | 1.37 | 1.63 | 0.74 | 1.12 | 0.93 | 0.62 | 0.43 | 0.33 |
nonadecanoic acid | ME252039 | 1.20 | 0.79 | 1.50 | 0.57 | 1.16 | 1.36 | 0.75 | 0.71 | 0.73 | 1.10 | 1.64 | 0.55 |
2-aminobutyric acid | ME252182 | 1.24 | 0.38 | 1.99 | 0.58 | 1.75 | 0.76 | 1.06 | 0.58 | 0.70 | 1.13 | 0.90 | 0.99 |
heptadecanoic acid | ME252092 | 1.99 | 0.49 | 1.83 | 0.74 | 1.61 | 0.80 | 0.71 | 0.85 | 1.01 | 0.59 | 0.80 | 0.83 |
pentadecanoic acid | ME252022 | 1.51 | 0.50 | 1.56 | 0.95 | 1.18 | 0.80 | 0.77 | 1.00 | 1.32 | 0.72 | 0.99 | 0.82 |
aspartic acid | ME252137 | 1.70 | 0.43 | 1.38 | 0.91 | 1.52 | 0.69 | 1.57 | 0.58 | 0.67 | 0.69 | 0.82 | 1.22 |
trans-4-hydroxyproline | ME251987 | 1.72 | 1.16 | 1.28 | 0.64 | 1.32 | 0.66 | 1.38 | 0.89 | 0.63 | 0.79 | 0.85 | 0.86 |
malonic acid | ME252058 | 1.49 | 1.02 | 0.69 | 0.84 | 1.98 | 0.87 | 1.05 | 0.88 | 0.85 | 1.16 | 0.67 | 0.63 |
N-acetylglutamate | ME252043 | 1.21 | 0.63 | 1.16 | 0.70 | 2.04 | 0.64 | 1.19 | 1.11 | 0.53 | 1.07 | 1.00 | 0.76 |
6-hydroxynicotinic acid | ME252150 | 1.25 | 0.52 | 1.37 | 0.64 | 1.55 | 1.27 | 1.17 | 0.49 | 1.02 | 1.05 | 0.79 | 0.93 |
adipic acid | ME252148 | 1.01 | 0.60 | 1.21 | 0.84 | 1.65 | 1.30 | 0.80 | 0.74 | 0.94 | 0.97 | 1.13 | 0.81 |
1-monopalmitin | ME252186 | 1.05 | 1.03 | 1.51 | 1.13 | 1.41 | 0.85 | 0.95 | 0.87 | 1.06 | 0.71 | 0.70 | 0.74 |
hexadecane | ME252091 | 0.98 | 0.87 | 1.02 | 0.85 | 1.76 | 0.92 | 1.05 | 0.78 | 1.07 | 0.81 | 1.04 | 0.84 |
hydroxylamine | ME252084 | 0.96 | 0.77 | 1.18 | 1.01 | 1.63 | 1.40 | 1.20 | 0.84 | 1.00 | 0.74 | 0.75 | 0.52 |
1,3,5-trimethylcyanuric acid | ME252192 | 0.99 | 0.87 | 1.07 | 0.92 | 1.54 | 1.15 | 1.09 | 1.03 | 0.94 | 0.81 | 0.84 | 0.77 |
urea | ME251981 | 1.15 | 0.90 | 0.94 | 0.85 | 1.48 | 1.06 | 1.17 | 1.14 | 1.06 | 0.89 | 0.76 | 0.64 |
3,4-dihydroxyhydrocinnamic acid NIST | ME252168 | 1.49 | 0.63 | 1.53 | 0.96 | 1.47 | 1.27 | 0.81 | 1.27 | 0.74 | 0.65 | 1.04 | 0.26 |
tyrosine | ME251984 | 1.22 | 0.75 | 1.48 | 0.99 | 1.29 | 1.24 | 1.29 | 0.81 | 0.50 | 0.53 | 0.97 | 1.00 |
capric acid | ME252131 | 1.53 | 0.42 | 1.36 | 0.69 | 1.44 | 1.18 | 1.10 | 1.24 | 0.73 | 0.73 | 0.69 | 1.02 |
tocopherol gamma- | ME251988 | 1.45 | 0.59 | 1.55 | 1.09 | 1.41 | 1.32 | 0.93 | 1.06 | 0.70 | 0.61 | 0.68 | 0.73 |
cysteine | ME252122 | 0.64 | 0.38 | 1.21 | 1.01 | 0.90 | 1.21 | 1.46 | 0.44 | 0.50 | 1.66 | 1.10 | 1.40 |
succinic acid | ME251998 | 0.75 | 0.33 | 0.35 | 1.13 | 0.69 | 0.73 | 2.24 | 0.62 | 0.72 | 1.90 | 1.14 | 1.34 |
arachidonic acid | ME252139 | 0.58 | 1.25 | 0.41 | 1.30 | 1.07 | 0.56 | 1.17 | 0.95 | 0.87 | 2.21 | 0.86 | 0.66 |
docosahexaenoic acid | ME252117 | 0.79 | 1.01 | 0.41 | 1.61 | 0.84 | 0.64 | 1.53 | 0.52 | 0.85 | 1.66 | 1.13 | 0.97 |
1-deoxyerythritol | ME252189 | 0.64 | 1.19 | 0.39 | 1.48 | 0.52 | 0.66 | 1.14 | 1.07 | 1.22 | 1.12 | 1.11 | 1.37 |
threonine | ME251992 | 1.15 | 1.13 | 0.43 | 1.01 | 0.42 | 0.83 | 1.39 | 0.99 | 0.92 | 1.33 | 0.97 | 1.46 |
4-hydroxyphenylacetic acid | ME252154 | 0.36 | 0.90 | 0.49 | 1.64 | 0.97 | 0.30 | 1.58 | 1.14 | 0.87 | 1.00 | 1.21 | 1.38 |
alanine-alanine | ME252146 | 0.34 | 0.92 | 0.46 | 1.28 | 0.44 | 0.72 | 1.86 | 1.29 | 0.89 | 1.30 | 0.90 | 1.43 |
2-hydroxybutanoic acid | ME252178 | 1.04 | 0.58 | 0.74 | 0.65 | 0.64 | 0.92 | 1.23 | 0.67 | 0.69 | 1.27 | 2.27 | 1.31 |
3-aminoisobutyric acid | ME252165 | 1.11 | 0.78 | 0.68 | 0.51 | 1.26 | 0.61 | 1.04 | 0.88 | 0.68 | 1.49 | 1.49 | 1.47 |
methionine | ME252051 | 1.13 | 0.71 | 0.89 | 0.95 | 0.73 | 0.73 | 1.38 | 0.58 | 0.58 | 1.46 | 1.43 | 1.46 |
tryptophan | ME251986 | 1.21 | 0.51 | 0.83 | 0.95 | 0.72 | 0.86 | 1.57 | 0.85 | 0.61 | 1.01 | 1.34 | 1.59 |
phenylalanine | ME252020 | 1.39 | 0.57 | 1.09 | 0.99 | 1.19 | 1.05 | 1.37 | 0.76 | 0.48 | 0.74 | 1.24 | 1.24 |
isoleucine | ME252076 | 1.47 | 0.56 | 0.71 | 0.95 | 1.10 | 0.75 | 1.04 | 0.82 | 0.80 | 1.01 | 1.28 | 1.62 |
leucine | ME252067 | 1.22 | 0.59 | 0.87 | 0.98 | 1.10 | 0.89 | 1.19 | 0.75 | 0.78 | 1.01 | 1.29 | 1.38 |
valine | ME251978 | 1.25 | 0.54 | 1.03 | 0.85 | 1.23 | 0.97 | 1.06 | 0.85 | 0.74 | 1.09 | 1.22 | 1.21 |
glycine | ME252095 | 0.96 | 0.91 | 1.01 | 1.09 | 0.98 | 1.00 | 1.04 | 0.76 | 1.01 | 0.75 | 1.40 | 1.08 |
phenylacetic acid | ME252021 | 0.93 | 0.96 | 0.98 | 0.99 | 1.21 | 0.64 | 1.20 | 0.96 | 1.38 | 0.66 | 1.01 | 1.05 |
beta-alanine | ME252134 | 0.40 | 0.81 | 0.61 | 0.87 | 0.94 | 0.91 | 1.33 | 0.98 | 0.98 | 1.32 | 1.46 | 1.22 |
glutamic acid | ME252102 | 0.65 | 0.77 | 0.83 | 1.06 | 0.88 | 1.12 | 0.97 | 1.04 | 0.90 | 0.77 | 1.21 | 1.72 |
oleic acid | ME252032 | 1.35 | 0.39 | 0.71 | 0.91 | 0.85 | 0.91 | 0.92 | 1.33 | 0.95 | 1.75 | 1.02 | 1.01 |
glutaric acid | ME252100 | 1.20 | 0.85 | 0.75 | 1.18 | 0.80 | 1.51 | 1.10 | 0.89 | 0.78 | 1.00 | 1.13 | 0.85 |
phosphoethanolamine | ME252018 | 0.97 | 0.62 | 1.21 | 0.89 | 0.69 | 1.09 | 1.41 | 1.49 | 0.94 | 1.24 | 0.61 | 0.84 |
thymine | ME251990 | 0.76 | 0.71 | 1.12 | 1.03 | 1.05 | 1.16 | 1.22 | 1.34 | 0.99 | 0.87 | 0.98 | 0.72 |
pipecolinic acid | ME252013 | 0.35 | 0.28 | 0.17 | 1.56 | 0.64 | 0.48 | 1.28 | 1.17 | 2.09 | 0.92 | 2.06 | 0.83 |
1-monoolein | ME252187 | 0.14 | 1.09 | 0.75 | 2.02 | 0.05 | 0.71 | 1.07 | 0.65 | 1.60 | 1.06 | 1.18 | 1.47 |
linoleic acid | ME252064 | 0.23 | 0.97 | 0.16 | 2.41 | 0.22 | 0.94 | 1.56 | 1.02 | 1.14 | 1.14 | 0.99 | 1.03 |
xylitol | ME251976 | 0.66 | 0.96 | 0.27 | 0.72 | 0.13 | 2.42 | 1.17 | 0.87 | 0.74 | 1.06 | 2.02 | 0.89 |
2-monoolein | ME252171 | 0.27 | 1.18 | 0.72 | 1.46 | 0.57 | 0.79 | 0.80 | 0.45 | 1.28 | 1.00 | 2.17 | 1.14 |
2-hydroxyglutaric acid | ME252177 | 0.14 | 1.17 | 0.29 | 0.78 | 0.43 | 1.48 | 1.54 | 1.22 | 1.06 | 0.70 | 2.25 | 0.73 |
benzoic acid | ME252135 | 0.41 | 1.80 | 0.44 | 0.60 | 0.62 | 1.00 | 0.95 | 1.10 | 1.14 | 0.75 | 2.17 | 0.86 |
guanine | ME252093 | 0.31 | 1.42 | 0.35 | 1.39 | 0.22 | 2.05 | 0.65 | 1.50 | 1.72 | 0.49 | 0.86 | 0.85 |
methanolphosphate | ME252052 | 0.40 | 1.17 | 0.64 | 1.15 | 1.04 | 2.60 | 0.61 | 0.96 | 1.15 | 0.81 | 0.76 | 0.55 |
4-pyridoxic acid | ME252153 | 0.42 | 1.54 | 0.38 | 0.50 | 1.00 | 1.56 | 0.62 | 1.25 | 1.27 | 0.91 | 1.17 | 1.23 |
2-hydroxyhexanoic acid | ME252176 | 0.15 | 1.70 | 0.88 | 1.09 | 0.63 | 1.67 | 0.74 | 1.18 | 1.01 | 0.95 | 0.94 | 0.85 |
4-hydroxybutyric acid | ME252156 | 0.42 | 1.15 | 0.85 | 0.91 | 0.89 | 1.88 | 0.89 | 1.20 | 1.23 | 0.76 | 0.91 | 0.76 |
indole-3-propionic acid | ME252080 | 0.32 | 1.65 | 1.26 | 0.78 | 0.45 | 0.40 | 0.86 | 1.28 | 1.19 | 1.56 | 0.95 | 1.12 |
2-deoxytetronic acid | ME252179 | 0.21 | 1.75 | 0.27 | 0.99 | 0.35 | 0.75 | 1.13 | 1.79 | 0.84 | 1.61 | 0.92 | 1.20 |
ethanolamine | ME252113 | 0.46 | 1.08 | 0.36 | 0.67 | 0.91 | 0.81 | 0.94 | 2.03 | 0.96 | 1.56 | 1.13 | 0.95 |
propane-1,3-diol NIST | ME252010 | 0.31 | 1.19 | 0.39 | 0.43 | 0.78 | 0.55 | 1.11 | 1.63 | 0.95 | 2.11 | 1.34 | 1.04 |
threitol | ME251994 | 0.24 | 1.99 | 0.95 | 0.79 | 0.52 | 1.05 | 1.44 | 0.75 | 0.89 | 1.02 | 1.28 | 0.90 |
ribitol | ME252005 | 0.18 | 1.86 | 0.82 | 1.44 | 0.58 | 0.70 | 1.49 | 1.16 | 1.35 | 0.72 | 0.96 | 0.53 |
3-phenyllactic acid | ME252159 | 0.10 | 1.77 | 0.49 | 1.26 | 0.51 | 1.09 | 1.25 | 1.23 | 1.11 | 1.25 | 0.78 | 0.94 |
p-hydroxylphenyllactic acid | ME252017 | 0.17 | 1.65 | 0.94 | 1.31 | 0.88 | 1.15 | 1.31 | 0.96 | 0.97 | 0.75 | 0.70 | 1.00 |
3-hydroxybenzoic acid | ME252163 | 0.14 | 1.38 | 0.28 | 1.43 | 0.29 | 1.10 | 1.30 | 1.41 | 1.83 | 0.65 | 1.20 | 0.77 |
histidine | ME252088 | 0.50 | 1.16 | 0.15 | 0.82 | 0.10 | 0.84 | 1.84 | 1.51 | 1.60 | 1.05 | 1.30 | 0.99 |
glycolic acid | ME252094 | 0.33 | 1.03 | 0.55 | 0.97 | 0.44 | 1.25 | 0.67 | 2.63 | 1.05 | 0.84 | 1.15 | 0.92 |
hypoxanthine | ME252083 | 0.24 | 1.01 | 0.52 | 1.11 | 0.61 | 1.29 | 1.06 | 2.12 | 1.07 | 0.88 | 1.23 | 0.67 |
biphenyl | ME252132 | 0.17 | 0.67 | 0.45 | 1.56 | 0.59 | 1.57 | 0.87 | 1.34 | 1.25 | 1.06 | 1.06 | 1.20 |
methionine sulfoxide | ME252050 | 0.45 | 0.81 | 0.45 | 1.19 | 0.84 | 1.20 | 0.91 | 1.71 | 1.51 | 1.14 | 0.57 | 1.08 |
serine | ME252001 | 1.08 | 1.55 | 0.78 | 1.12 | 0.61 | 1.07 | 0.90 | 1.51 | 1.03 | 0.74 | 0.70 | 0.92 |
alanine | ME252147 | 0.66 | 1.09 | 0.79 | 1.09 | 0.78 | 1.24 | 1.03 | 1.08 | 1.20 | 0.99 | 1.01 | 0.96 |
hydroxycarbamate NIST | ME252085 | 0.29 | 1.31 | 0.76 | 0.80 | 0.74 | 1.08 | 1.05 | 1.35 | 1.29 | 1.25 | 0.90 | 1.01 |
3-hydroxyphenylacetic acid | ME252161 | 0.45 | 1.27 | 0.58 | 1.29 | 0.64 | 0.97 | 1.17 | 1.53 | 1.12 | 0.67 | 1.05 | 1.12 |
nicotinic acid | ME252040 | 0.38 | 1.28 | 0.63 | 1.06 | 0.87 | 1.23 | 0.85 | 1.78 | 1.05 | 0.96 | 0.82 | 0.95 |
uracil | ME251982 | 0.58 | 0.87 | 0.72 | 0.85 | 0.88 | 0.93 | 1.28 | 1.81 | 1.11 | 1.04 | 1.10 | 0.72 |
xanthine | ME251977 | 0.37 | 0.89 | 0.66 | 0.94 | 0.60 | 1.01 | 1.36 | 1.60 | 1.06 | 1.16 | 1.29 | 0.91 |
isothreonic acid | ME252073 | 0.40 | 1.24 | 0.88 | 0.99 | 0.72 | 0.90 | 1.11 | 1.81 | 1.54 | 0.81 | 0.97 | 0.49 |
oleamide NIST | ME252033 | 0.31 | 1.02 | 0.86 | 0.92 | 0.44 | 1.06 | 1.44 | 1.55 | 1.52 | 1.03 | 0.74 | 0.93 |
thymidine | ME251991 | 0.72 | 0.99 | 0.77 | 1.75 | 0.53 | 0.67 | 1.26 | 1.00 | 2.19 | 0.67 | 0.70 | 0.68 |
arabinose | ME252142 | 0.42 | 1.43 | 1.10 | 2.01 | 0.32 | 0.96 | 0.67 | 1.60 | 1.67 | 0.74 | 0.41 | 0.51 |
citramalic acid | ME252126 | 0.60 | 1.05 | 1.21 | 1.80 | 0.66 | 1.49 | 0.98 | 1.25 | 1.57 | 0.56 | 0.44 | 0.28 |
parabanic acid NIST | ME252024 | 0.81 | 1.00 | 0.73 | 1.05 | 0.64 | 1.32 | 0.96 | 1.78 | 1.85 | 0.74 | 0.62 | 0.45 |
urocanic acid | ME251979 | 0.39 | 1.10 | 0.73 | 1.42 | 0.47 | 1.07 | 1.59 | 1.78 | 1.76 | 0.40 | 0.50 | 0.65 |
threonic acid | ME251993 | 0.21 | 1.35 | 0.69 | 1.04 | 1.86 | 0.97 | 0.65 | 1.33 | 2.13 | 0.77 | 0.38 | 0.42 |
4-hydroxybenzoate | ME252157 | 0.58 | 1.45 | 0.89 | 1.46 | 1.30 | 1.33 | 0.71 | 2.00 | 0.88 | 0.28 | 0.61 | 0.40 |
pseudo-uridine | ME252009 | 0.54 | 1.78 | 1.15 | 1.64 | 1.38 | 1.14 | 0.62 | 1.02 | 1.20 | 0.54 | 0.47 | 0.41 |
N-acetylputrescine | ME252041 | 0.20 | 1.33 | 0.34 | 0.14 | 0.54 | 1.24 | 0.80 | 1.16 | 0.82 | 0.67 | 2.25 | 2.31 |
lysine | ME252062 | 0.07 | 1.02 | 0.34 | 0.80 | 0.11 | 0.80 | 0.92 | 1.33 | 2.22 | 1.06 | 1.47 | 1.62 |
N-acetylornithine | ME252042 | 0.05 | 1.48 | 0.08 | 0.81 | 0.09 | 0.69 | 0.51 | 1.92 | 2.18 | 1.47 | 0.82 | 1.67 |
piperidone | ME252012 | 0.41 | 0.60 | 0.30 | 1.05 | 0.31 | 0.43 | 0.74 | 2.17 | 0.70 | 0.96 | 1.50 | 2.69 |
2,4-diaminobutyric acid | ME252185 | 0.23 | 0.85 | 0.41 | 1.23 | 0.40 | 0.66 | 0.98 | 2.44 | 0.90 | 0.59 | 1.20 | 1.90 |
2,6-diaminopimelic acid | ME252184 | 0.20 | 0.92 | 0.19 | 0.63 | 0.69 | 0.81 | 0.98 | 2.23 | 1.28 | 1.06 | 1.13 | 1.70 |
lactic acid | ME252070 | 0.05 | 1.52 | 0.14 | 0.94 | 0.18 | 1.23 | 1.47 | 1.13 | 1.06 | 1.47 | 1.22 | 1.35 |
3-hydroxypropionic acid | ME252160 | 0.28 | 1.53 | 0.47 | 0.78 | 0.59 | 0.69 | 1.03 | 1.23 | 1.09 | 1.33 | 1.62 | 1.20 |
ornithine | ME252031 | 0.07 | 1.22 | 0.26 | 0.95 | 0.38 | 0.93 | 1.06 | 1.25 | 1.36 | 0.93 | 1.60 | 1.76 |
3-(3-hydroxyphenyl)propionic acid | ME252170 | 0.14 | 0.86 | 0.21 | 1.25 | 0.08 | 1.43 | 1.25 | 1.22 | 1.15 | 1.13 | 1.11 | 1.94 |
aminomalonate | ME252143 | 0.31 | 0.79 | 0.60 | 0.76 | 0.39 | 1.26 | 0.84 | 1.45 | 1.38 | 1.26 | 1.32 | 1.46 |
norvaline | ME252037 | 0.45 | 0.52 | 0.53 | 0.75 | 0.76 | 1.00 | 0.92 | 1.44 | 1.28 | 1.50 | 0.85 | 1.86 |
indole-3-lactate | ME252081 | 0.12 | 0.84 | 0.43 | 0.65 | 0.31 | 0.61 | 2.11 | 1.38 | 0.75 | 1.63 | 1.28 | 1.68 |
indole-3-acetate | ME252082 | 0.31 | 0.69 | 0.29 | 0.94 | 0.57 | 0.29 | 1.36 | 1.25 | 0.65 | 1.51 | 2.12 | 1.84 |
5-aminovaleric acid | ME252152 | 0.11 | 0.84 | 0.21 | 1.14 | 0.26 | 0.65 | 1.25 | 1.30 | 0.97 | 1.55 | 1.85 | 1.65 |
homoserine | ME252087 | 0.19 | 0.65 | 0.20 | 1.09 | 0.29 | 0.65 | 1.34 | 0.88 | 1.34 | 1.38 | 1.74 | 2.04 |
1-hexadecanol | ME252188 | 1.37 | 0.31 | 1.93 | 0.42 | 4.22 | 0.54 | 0.33 | 0.44 | 0.40 | 0.39 | 0.90 | 0.83 |
uric acid | ME251980 | 0.95 | 0.20 | 3.16 | 1.11 | 2.06 | 0.95 | 0.88 | 0.38 | 0.39 | 0.44 | 0.66 | 0.81 |
tocopherol alpha- | ME251989 | 2.95 | 0.24 | 3.51 | 0.42 | 2.59 | 0.99 | 0.42 | 0.39 | 0.21 | 0.29 | 0.27 | 0.23 |
inositol-4-monophosphate | ME252078 | 1.74 | 0.29 | 3.42 | 0.55 | 2.41 | 1.25 | 0.70 | 0.48 | 0.39 | 0.30 | 0.40 | 0.25 |
behenic acid | ME252136 | 2.23 | 0.33 | 3.83 | 0.30 | 2.25 | 0.64 | 0.51 | 0.59 | 0.50 | 0.38 | 0.42 | 0.33 |
dihydrocholesterol | ME252118 | 2.08 | 0.31 | 4.46 | 0.53 | 2.27 | 0.81 | 0.32 | 0.38 | 0.58 | 0.18 | 0.16 | 0.18 |
lignoceric acid | ME252065 | 1.86 | 0.20 | 5.16 | 0.33 | 2.50 | 0.49 | 0.27 | 0.29 | 0.26 | 0.47 | 0.19 | 0.20 |
quinolinic acid | ME252006 | 1.75 | 0.28 | 4.50 | 0.73 | 1.53 | 0.69 | 0.61 | 0.46 | 0.21 | 0.33 | 0.85 | 0.25 |
fumaric acid | ME252110 | 2.05 | 0.41 | 2.39 | 0.51 | 1.70 | 1.07 | 2.21 | 0.64 | 0.55 | 0.27 | 0.22 | 0.24 |
malic acid | ME252059 | 1.61 | 0.65 | 2.07 | 0.74 | 1.33 | 1.09 | 1.81 | 0.98 | 0.85 | 0.46 | 0.32 | 0.24 |
2-isopropylmalic acid | ME252175 | 2.44 | 0.49 | 1.00 | 0.27 | 3.15 | 1.11 | 1.23 | 0.46 | 0.42 | 0.49 | 0.93 | 0.37 |
glycerol-alpha-phosphate | ME252096 | 2.12 | 0.64 | 0.92 | 0.62 | 2.81 | 1.28 | 1.55 | 0.64 | 0.43 | 0.53 | 0.48 | 0.26 |
beta-glutamic acid | ME252133 | 1.98 | 0.56 | 2.05 | 0.45 | 1.83 | 2.14 | 0.34 | 0.89 | 0.59 | 0.44 | 0.44 | 0.54 |
3-hydroxy-3-methylglutaric acid | ME252164 | 1.06 | 0.76 | 2.41 | 0.44 | 2.93 | 0.87 | 0.62 | 0.63 | 0.67 | 0.79 | 0.49 | 0.35 |
alpha-ketoglutarate | ME252144 | 2.17 | 1.20 | 2.84 | 0.73 | 1.94 | 0.73 | 0.69 | 0.89 | 0.39 | 0.20 | 0.29 | 0.22 |
palmitoleic acid | ME252026 | 2.56 | 0.24 | 2.02 | 0.41 | 2.39 | 0.57 | 0.68 | 0.78 | 0.49 | 1.08 | 0.59 | 0.56 |
arachidic acid | ME252140 | 2.07 | 0.48 | 2.92 | 0.60 | 2.70 | 0.87 | 0.40 | 0.43 | 0.73 | 0.28 | 0.39 | 0.40 |
stearic acid | ME251999 | 2.53 | 0.31 | 3.10 | 0.77 | 2.53 | 0.79 | 0.40 | 0.41 | 0.48 | 0.25 | 0.34 | 0.47 |
myristic acid | ME252047 | 2.69 | 0.18 | 2.32 | 0.50 | 2.97 | 0.70 | 0.42 | 0.60 | 0.56 | 0.52 | 0.49 | 0.47 |
2-ketoisocaproic acid | ME252173 | 1.98 | 0.48 | 2.50 | 0.59 | 2.91 | 0.58 | 0.52 | 0.73 | 0.44 | 0.58 | 0.47 | 0.48 |
palmitic acid | ME252027 | 2.18 | 0.35 | 2.35 | 0.63 | 2.74 | 0.80 | 0.48 | 0.56 | 0.57 | 0.63 | 0.53 | 0.46 |
isoheptadecanoic acid NIST | ME252077 | 3.37 | 0.36 | 2.22 | 0.73 | 1.85 | 0.70 | 0.53 | 0.64 | 0.70 | 0.33 | 0.46 | 0.70 |
oxoproline | ME252028 | 2.24 | 0.42 | 1.61 | 0.95 | 1.69 | 1.18 | 1.31 | 0.42 | 0.56 | 0.47 | 0.93 | 0.53 |
phosphate | ME252019 | 2.25 | 0.67 | 1.51 | 1.29 | 2.23 | 1.01 | 0.36 | 0.39 | 1.05 | 0.67 | 0.53 | 0.36 |
cholesterol | ME252128 | 0.74 | 0.41 | 6.24 | 0.52 | 0.99 | 0.52 | 0.49 | 0.65 | 0.52 | 0.26 | 0.28 | 0.31 |
lanosterol | ME252068 | 2.75 | 0.05 | 5.79 | 0.05 | 3.23 | 0.25 | 0.06 | 0.06 | 0.06 | 0.04 | 0.05 | 0.05 |
Factors:
F1 | Day:-1 | Treatment:Acute |
F2 | Day:1 | Treatment:Acute |
F3 | Day:-1 | Treatment:Chronic |
F4 | Day:1 | Treatment:Chronic |
F5 | Day:-1 | Treatment:Control |
F6 | Day:1 | Treatment:Control |
F7 | Day:3 | Treatment:Acute |
F8 | Day:3 | Treatment:Chronic |
F9 | Day:3 | Treatment:Control |
F10 | Day:6 | Treatment:Acute |
F11 | Day:6 | Treatment:Chronic |
F12 | Day:6 | Treatment:Control |