Clustering data with hclust algorithm for (Study ST001170)
(Analysis AN001935)Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hypoxanthine | ME279281 | 1.84 | 1.63 | 1.13 | 0.98 | 0.59 | 0.76 | 0.29 | 0.90 | 3.80 | 0.18 | 0.55 | 0.84 | 0.09 | 0.37 | NA |
NADH | ME279297 | 1.82 | 2.16 | 1.37 | 0.32 | 1.68 | 2.31 | 0.83 | 0.91 | 0.53 | 0.66 | 0.17 | 0.21 | 0.38 | 0.35 | NA |
NADPH | ME279299 | 1.69 | 2.63 | 1.55 | 0.54 | 0.74 | 2.03 | 0.47 | 0.74 | 1.28 | 0.34 | 0.34 | 0.68 | 0.34 | 0.34 | NA |
Fructose 1,6-bisphosphate | ME279303 | 1.37 | 1.13 | 1.33 | 0.81 | 2.42 | 1.00 | 1.04 | 0.88 | 0.77 | 0.53 | 0.62 | 1.02 | 0.33 | 0.53 | NA |
Acetyl-CoA | ME279308 | NA | NA | 0.91 | NA | NA | 0.91 | NA | 1.31 | 0.91 | 0.91 | 0.91 | 0.91 | 0.91 | 0.91 | NA |
Alanine | ME279262 | 0.25 | 0.28 | 0.71 | 0.74 | 0.22 | 1.12 | 0.19 | 1.71 | 1.29 | 0.28 | 1.40 | 2.75 | 1.05 | 1.60 | NA |
ADP | ME279283 | 0.63 | 0.80 | 0.82 | 0.72 | 0.54 | 0.98 | 0.37 | 1.05 | 1.24 | 0.38 | 1.36 | 1.76 | 1.30 | 2.17 | NA |
dGDP | ME279291 | 0.63 | 0.81 | 0.83 | 0.72 | 0.54 | 0.99 | 0.37 | 1.17 | 1.25 | 0.38 | 1.06 | 1.77 | 1.31 | 2.19 | NA |
Lactic acid | ME279307 | 0.63 | 0.43 | 1.11 | 0.57 | 0.38 | 1.59 | 0.41 | 2.14 | 1.51 | 0.31 | 0.83 | 1.26 | 0.50 | 1.07 | NA |
Pyruvic acid | ME279306 | 0.68 | 0.41 | 0.92 | 0.68 | 0.34 | 1.29 | 0.34 | 2.54 | 1.29 | 0.34 | 0.68 | 1.08 | 0.61 | 1.36 | NA |
dTDP | ME279292 | 0.88 | 0.88 | 0.88 | 1.41 | 0.44 | 0.71 | 0.53 | 1.06 | 2.30 | 0.53 | 0.88 | 1.77 | 0.44 | 1.33 | NA |
Malate | ME279315 | 1.22 | 0.66 | 1.40 | 1.58 | 0.53 | 1.25 | 0.47 | 1.04 | 2.16 | 0.39 | 0.64 | 1.22 | 0.26 | 0.74 | NA |
Succinate | ME279313 | 0.66 | 0.51 | 1.29 | 1.64 | 0.42 | 1.21 | 0.35 | 1.22 | 2.06 | 0.31 | 0.88 | 1.35 | 0.64 | 0.95 | NA |
α-Ketoglutarate | ME279312 | 0.86 | 0.55 | 1.37 | 1.38 | 0.33 | 1.16 | 0.39 | 1.20 | 2.35 | 0.33 | 0.89 | 1.38 | 0.47 | 0.75 | NA |
Oxaloacetate | ME279309 | 0.82 | NA | 0.82 | 0.82 | 0.82 | 0.82 | NA | 0.82 | 1.63 | 0.82 | 1.14 | 1.63 | 0.82 | 0.98 | NA |
Glutamate | ME279264 | 0.77 | 0.71 | 1.11 | 1.35 | 0.62 | 0.98 | 0.55 | 1.19 | 1.51 | 0.45 | 1.06 | 1.73 | 0.63 | 1.04 | NA |
Uracil | ME279280 | 0.57 | 0.33 | 0.84 | 1.18 | 0.36 | 1.16 | 0.39 | 1.43 | 1.52 | 0.47 | 1.83 | 1.53 | 0.75 | 1.39 | NA |
Aconitate | ME279311 | 0.54 | 0.29 | 0.85 | 1.43 | 0.31 | 1.20 | 0.41 | 1.29 | 1.79 | 0.48 | 1.25 | 1.70 | 0.79 | 1.52 | NA |
Citrate | ME279310 | 0.54 | 0.26 | 0.89 | 1.42 | 0.33 | 1.15 | 0.38 | 1.20 | 1.77 | 0.50 | 1.11 | 1.99 | 0.89 | 1.48 | NA |
dCDP | ME279290 | 0.91 | 0.91 | 0.91 | 1.27 | 0.91 | 0.91 | 0.91 | 1.09 | 1.09 | NA | 0.91 | 1.27 | 0.91 | 0.91 | NA |
Taurine | ME279278 | 0.75 | 1.03 | 1.04 | 1.65 | 0.73 | 0.47 | 0.27 | 1.09 | 1.47 | 0.23 | 1.28 | 1.43 | 0.96 | 1.47 | NA |
CTP | ME279287 | 1.38 | 1.61 | 1.45 | 1.38 | 1.15 | 1.08 | 0.64 | 0.97 | 1.47 | 0.37 | 0.57 | 0.90 | 0.19 | 0.42 | NA |
Glutamine | ME279265 | 1.51 | 1.61 | 1.22 | 1.39 | 0.75 | 1.01 | 0.67 | 1.11 | 1.34 | 0.58 | 0.43 | 1.07 | 0.40 | 0.60 | NA |
Glyceraldehyde-3-phosphate | ME279304 | 0.79 | 0.84 | 1.25 | 1.75 | 1.21 | 0.88 | 0.67 | 1.13 | 1.55 | 0.54 | 0.96 | 1.00 | 0.33 | 0.71 | NA |
NADP+ | ME279298 | 0.69 | 0.69 | 0.97 | 1.52 | 0.69 | 0.97 | 0.69 | 1.03 | 1.38 | 0.69 | 0.69 | 1.38 | NA | 0.69 | NA |
Orotidine | ME279279 | 1.40 | 0.88 | 1.05 | 1.40 | 0.88 | 1.05 | 0.88 | 1.05 | 0.88 | 0.88 | 0.88 | 0.88 | 0.88 | 0.88 | NA |
Oxidized glutathione | ME279300 | 1.50 | 0.87 | 1.04 | 1.02 | 0.89 | 1.47 | 0.87 | 0.94 | 0.94 | 0.72 | 0.74 | 1.12 | 0.83 | 1.08 | NA |
3-Phosphoglyceric acid | ME279305 | 1.39 | 1.02 | 1.57 | 0.73 | 0.73 | 1.68 | 0.51 | 1.21 | 1.10 | 0.44 | 0.73 | 1.02 | 0.37 | 0.73 | NA |
Cytidine | ME279282 | 1.49 | 1.15 | 1.34 | 1.12 | 1.20 | 1.30 | 0.87 | 1.10 | 1.04 | 0.75 | 0.33 | 0.88 | 0.37 | 0.60 | NA |
Serine | ME279271 | 1.16 | 1.24 | 1.25 | 0.90 | 0.74 | 1.57 | 0.81 | 1.23 | 1.06 | 0.85 | 0.50 | 0.95 | 0.37 | 0.93 | NA |
Valine | ME279274 | 1.04 | 1.26 | 1.09 | 0.96 | 0.86 | 1.22 | 0.71 | 1.38 | 1.00 | 0.76 | 0.66 | 1.01 | 0.63 | 0.96 | NA |
Phenylalanine | ME279270 | 1.21 | 1.34 | 1.23 | 1.04 | 0.66 | 1.37 | 0.63 | 1.38 | 1.01 | 0.70 | 0.60 | 0.98 | 0.49 | 0.76 | NA |
Tryptophan | ME279273 | 1.26 | 1.34 | 1.20 | 1.11 | 0.76 | 1.28 | 0.63 | 1.26 | 1.06 | 0.71 | 0.61 | 1.01 | 0.51 | 0.81 | NA |
Histidine | ME279267 | 0.73 | 0.94 | 0.97 | 0.90 | 0.57 | 1.25 | 0.45 | 1.57 | 1.05 | 0.49 | 1.63 | 1.02 | 0.95 | 0.94 | NA |
Homoserine | ME279277 | 0.82 | 0.90 | 1.04 | 0.73 | 0.52 | 1.63 | 0.52 | 1.76 | 0.99 | 0.59 | 1.17 | 1.02 | 0.58 | 0.95 | NA |
Threonine | ME279272 | 0.82 | 0.90 | 1.04 | 0.72 | 0.52 | 1.63 | 0.53 | 1.76 | 0.99 | 0.59 | 1.17 | 1.01 | 0.58 | 0.95 | NA |
UDP | ME279285 | 0.97 | 0.97 | 1.19 | 1.09 | 0.49 | 1.23 | 0.29 | 1.57 | 1.37 | 0.27 | 1.34 | 1.28 | 0.38 | 0.79 | NA |
NAD+ | ME279296 | 0.74 | 0.69 | 1.33 | 1.22 | 0.69 | 1.31 | 0.45 | 1.44 | 1.26 | 0.50 | 0.89 | 1.07 | 0.63 | 1.01 | NA |
dGTP | ME279294 | 1.01 | 1.04 | 1.12 | 1.07 | 0.69 | 1.13 | 0.55 | 1.23 | 1.42 | 0.61 | 0.92 | 1.13 | 0.67 | 1.04 | NA |
Glycine | ME279266 | 0.98 | 1.24 | 1.20 | 1.14 | 0.64 | 1.26 | 0.41 | 1.48 | 1.17 | 0.41 | 0.82 | 0.96 | 0.63 | 1.01 | NA |
Tyrosine | ME279275 | 0.83 | 1.03 | 0.93 | 0.96 | 0.71 | 1.03 | 0.62 | 1.35 | 1.12 | 0.63 | 1.34 | 1.19 | 0.84 | 1.15 | NA |
Methionine | ME279269 | 1.15 | 1.19 | 1.13 | 0.95 | 0.71 | 1.30 | 0.57 | 1.34 | 1.04 | 0.58 | 1.05 | 0.95 | 0.72 | 0.87 | NA |
ATP | ME279286 | 1.00 | 1.02 | 1.10 | 1.05 | 0.68 | 1.11 | 0.54 | 1.31 | 1.24 | 0.60 | 1.31 | 1.12 | 0.66 | 0.83 | NA |
Leucine | ME279268 | 1.04 | 1.14 | 1.06 | 0.95 | 0.61 | 1.23 | 0.50 | 1.41 | 1.11 | 0.54 | 1.36 | 1.06 | 0.60 | 0.91 | NA |
Aspartate | ME279263 | 1.11 | 1.04 | 1.27 | 1.08 | 0.50 | 1.71 | 0.50 | 1.39 | 1.57 | 0.43 | 0.80 | 1.20 | 0.28 | 0.45 | NA |
UTP | ME279289 | 1.38 | 1.20 | 1.41 | 1.12 | 0.53 | 1.21 | 0.34 | 1.17 | 1.59 | 0.26 | 1.00 | 1.45 | 0.25 | 0.49 | NA |
CDP | ME279284 | 1.18 | 1.14 | 1.24 | 1.42 | 0.99 | 1.14 | 0.52 | 1.19 | 1.30 | 0.33 | 0.99 | 1.05 | 0.39 | 0.70 | NA |
dCTP | ME279293 | 1.13 | 1.30 | 1.19 | 1.19 | 0.74 | 1.25 | 0.57 | 1.08 | 1.36 | 0.40 | 1.19 | 1.19 | 0.34 | 0.79 | NA |
Reduced glutathione | ME279301 | 1.13 | 0.87 | 1.18 | 1.56 | 0.61 | 1.24 | 0.46 | 1.13 | 1.60 | 0.37 | 1.14 | 1.15 | 0.56 | 0.67 | NA |
Fumarate | ME279314 | 1.22 | 0.70 | 1.42 | 1.37 | 0.60 | 1.34 | 0.57 | 1.03 | 1.66 | 0.46 | 0.79 | 1.36 | 0.30 | 0.71 | NA |
Homocysteine | ME279276 | 1.35 | 0.72 | 1.38 | 1.43 | 0.62 | 1.35 | 0.62 | 1.23 | 1.30 | 0.52 | 0.85 | 1.10 | 0.27 | 0.66 | NA |
TTP | ME279288 | 1.34 | 1.02 | 1.04 | 1.57 | 0.71 | 0.86 | 0.63 | 0.98 | 1.77 | 0.51 | 0.79 | 1.42 | 0.43 | 0.90 | NA |
dCMP | ME279295 | 1.35 | 1.05 | 0.93 | 1.17 | 0.67 | 1.27 | 0.83 | 1.15 | 1.27 | 0.61 | 1.03 | 1.15 | 0.32 | 1.13 | NA |
Glucose-6-phosphate | ME279302 | 1.19 | 1.00 | 1.07 | 1.16 | 0.82 | 1.16 | 0.64 | 1.03 | 1.31 | 0.64 | 0.86 | 1.37 | 0.32 | 1.31 | NA |
Factors:
F1 | hours:12 | Doxorubicin dosage(μM):- |
F2 | hours:12 | Doxorubicin dosage(μM):10 |
F3 | hours:24 | Doxorubicin dosage(μM):- |
F4 | hours:24 | Doxorubicin dosage(μM):0.1 |
F5 | hours:24 | Doxorubicin dosage(μM):10 |
F6 | hours:36 | Doxorubicin dosage(μM):- |
F7 | hours:36 | Doxorubicin dosage(μM):10 |
F8 | hours:48 | Doxorubicin dosage(μM):- |
F9 | hours:48 | Doxorubicin dosage(μM):0.1 |
F10 | hours:48 | Doxorubicin dosage(μM):10 |
F11 | hours:72 | Doxorubicin dosage(μM):- |
F12 | hours:72 | Doxorubicin dosage(μM):0.1 |
F13 | hours:96 | Doxorubicin dosage(μM):- |
F14 | hours:96 | Doxorubicin dosage(μM):0.1 |
F15 | hours:- | Doxorubicin dosage(μM):- |