Clustering data with hclust algorithm for (Study ST001515)
(Analysis AN002511)Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
4-acetamidophenol | ME364915 | 0.01 | 0.51 | 0.67 | 3.54 | 0.77 | 0.03 | 1.41 | 3.09 | 1.99 | 0.70 | 2.52 | 1.47 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.02 |
cotinine | ME364940 | 1.43 | 0.68 | 0.37 | 1.05 | 0.27 | 4.38 | 1.24 | 0.69 | 0.47 | 1.25 | 0.36 | 2.51 | 0.51 | 0.22 | 0.24 | 0.46 | 0.22 | 1.04 |
theobromine | ME365051 | 1.05 | 0.62 | 0.54 | 0.94 | 0.37 | 2.29 | 0.67 | 0.23 | 0.17 | 0.63 | 0.17 | 3.28 | 1.19 | 0.57 | 0.29 | 1.07 | 0.20 | 3.62 |
pipecolate | ME365036 | 1.08 | 0.42 | 0.28 | 0.75 | 0.24 | 2.81 | 0.94 | 0.31 | 0.31 | 0.65 | 0.29 | 2.80 | 1.16 | 0.83 | 0.74 | 0.93 | 0.64 | 2.73 |
trigonelline (N^-methylnicotinate) | ME365057 | 0.76 | 0.80 | 0.50 | 0.37 | 0.33 | 2.33 | 0.91 | 0.92 | 0.68 | 0.52 | 0.57 | 2.90 | 0.76 | 1.32 | 0.73 | 0.48 | 0.63 | 2.42 |
alliin | ME364926 | 0.45 | 0.21 | 0.15 | 0.23 | 0.61 | 2.19 | 0.53 | 0.19 | 0.15 | 0.32 | 1.32 | 2.97 | 0.65 | 0.91 | 0.19 | 0.50 | 3.04 | 3.42 |
3-hydroxystachydrine* | ME364910 | 0.95 | 0.23 | 0.40 | 0.62 | 1.08 | 1.42 | 1.11 | 0.24 | 0.55 | 0.69 | 1.59 | 1.63 | 1.05 | 0.35 | 0.81 | 0.80 | 2.72 | 1.70 |
N-acetylalliin | ME365016 | 0.26 | 0.64 | 0.17 | 0.33 | 1.61 | 1.70 | 0.41 | 0.80 | 0.15 | 0.39 | 2.89 | 2.06 | 0.46 | 0.82 | 0.17 | 0.39 | 2.65 | 2.01 |
3-(cystein-S-yl)acetaminophen* | ME364905 | 0.51 | 0.97 | 1.22 | 1.18 | 1.37 | 0.51 | 1.64 | 0.51 | 2.15 | 0.83 | 2.53 | 1.13 | 0.51 | 0.51 | 0.51 | 0.51 | 0.51 | 0.51 |
glutamine conjugate of C7H12O2* | ME364975 | 0.64 | 1.67 | 1.45 | 0.11 | 1.39 | 0.72 | 0.86 | 0.94 | 1.40 | 0.25 | 1.81 | 0.83 | 1.04 | 0.61 | 0.65 | 1.80 | 0.95 | 0.92 |
hexanoylglutamine | ME364981 | 0.47 | 1.53 | 1.41 | 0.16 | 1.23 | 0.36 | 0.98 | 1.37 | 2.04 | 0.45 | 2.11 | 0.70 | 0.87 | 0.60 | 0.47 | 1.59 | 0.73 | 0.72 |
(R)-3-hydroxybutyrylcarnitine | ME364889 | 0.30 | 2.46 | 2.16 | 0.19 | 2.46 | 0.41 | 0.51 | 1.39 | 1.58 | 0.35 | 1.81 | 0.49 | 0.48 | 0.31 | 0.32 | 1.61 | 0.51 | 0.58 |
N-acetyl-1-methylhistidine* | ME365014 | 1.06 | 2.28 | 2.20 | 1.12 | 1.75 | 0.79 | 0.86 | 1.54 | 0.95 | 0.65 | 0.90 | 0.58 | 0.72 | 0.43 | 0.54 | 0.51 | 0.47 | 0.50 |
xanthurenate | ME365064 | 0.63 | 1.98 | 2.25 | 0.47 | 2.08 | 0.46 | 0.74 | 1.41 | 1.53 | 0.40 | 1.43 | 0.62 | 0.79 | 0.62 | 0.82 | 0.49 | 0.61 | 0.64 |
2-methylbutyrylglycine (C5) | ME364899 | 1.54 | 0.51 | 1.64 | 1.14 | 0.34 | 0.32 | 1.45 | 0.42 | 1.73 | 0.93 | 0.33 | 0.38 | 2.16 | 0.49 | 2.17 | 1.59 | 0.55 | 0.48 |
N-methylhydroxyproline | ME365027 | 1.32 | 0.42 | 0.33 | 1.23 | 0.30 | 1.53 | 1.61 | 0.46 | 0.42 | 1.11 | 0.58 | 1.86 | 1.31 | 0.75 | 0.77 | 1.16 | 1.55 | 1.13 |
N-methylproline | ME365029 | 1.29 | 0.50 | 0.42 | 1.01 | 0.48 | 1.64 | 1.35 | 0.49 | 0.49 | 1.19 | 0.73 | 1.84 | 1.12 | 0.63 | 0.80 | 1.01 | 1.33 | 1.53 |
3-methylhistidine | ME364913 | 1.06 | 0.87 | 0.45 | 0.58 | 0.49 | 1.97 | 0.85 | 0.70 | 0.53 | 0.57 | 0.53 | 1.61 | 1.13 | 1.61 | 1.02 | 0.93 | 1.39 | 1.95 |
S-methylcysteine sulfoxide | ME365046 | 1.30 | 0.56 | 0.25 | 0.60 | 0.33 | 1.90 | 1.32 | 0.58 | 0.36 | 0.74 | 0.65 | 1.98 | 1.07 | 1.36 | 0.91 | 1.07 | 1.51 | 1.59 |
2-piperidinone | ME364903 | 0.78 | 0.51 | 0.42 | 0.58 | 0.46 | 0.61 | 1.31 | 0.82 | 0.53 | 1.14 | 0.85 | 1.14 | 1.38 | 1.18 | 1.54 | 1.33 | 1.87 | 1.74 |
leucylalanine | ME364996 | 0.72 | 1.54 | 1.12 | 0.61 | 0.71 | 0.55 | 0.97 | 1.36 | 1.28 | 0.72 | 0.80 | 0.81 | 1.28 | 0.98 | 1.03 | 1.68 | 0.99 | 0.89 |
picolinoylglycine | ME365035 | 0.87 | 1.28 | 1.29 | 0.57 | 1.21 | 0.85 | 0.98 | 1.12 | 1.41 | 0.51 | 1.26 | 0.75 | 1.26 | 1.23 | 0.87 | 0.52 | 1.02 | 1.07 |
aspartate | ME364930 | 1.26 | 0.83 | 0.68 | 1.79 | 0.60 | 1.23 | 1.26 | 0.75 | 0.74 | 1.52 | 0.65 | 1.06 | 1.01 | 0.84 | 0.90 | 1.03 | 0.84 | 0.88 |
N,N-dimethylalanine | ME365004 | 1.67 | 0.89 | 0.65 | 1.48 | 0.59 | 1.75 | 1.17 | 0.54 | 0.65 | 1.11 | 0.51 | 1.28 | 0.93 | 1.02 | 0.88 | 1.15 | 0.82 | 0.90 |
phenylacetylcarnitine | ME365031 | 1.89 | 1.56 | 0.86 | 1.54 | 0.77 | 0.91 | 0.94 | 1.36 | 0.70 | 0.97 | 0.86 | 0.89 | 0.89 | 1.24 | 0.57 | 0.79 | 0.58 | 0.63 |
argininate* | ME364927 | 1.39 | 1.88 | 1.11 | 1.03 | 0.74 | 1.33 | 1.00 | 1.16 | 0.78 | 0.72 | 0.61 | 0.95 | 0.88 | 1.11 | 0.89 | 0.68 | 0.94 | 0.85 |
N2-acetyl,N6-methyllysine | ME365009 | 1.41 | 1.43 | 1.18 | 1.25 | 0.96 | 1.31 | 1.04 | 0.93 | 0.96 | 0.90 | 0.99 | 0.92 | 0.77 | 0.56 | 0.80 | 0.86 | 0.82 | 0.77 |
tryptophan betaine | ME365060 | 1.60 | 1.30 | 1.09 | 1.44 | 0.78 | 1.53 | 1.05 | 0.87 | 0.79 | 1.37 | 0.86 | 1.11 | 0.67 | 0.70 | 0.61 | 0.70 | 0.64 | 0.69 |
2-methylserine | ME364900 | 1.65 | 0.67 | 0.65 | 0.89 | 0.85 | 0.87 | 0.97 | 0.86 | 1.02 | 1.14 | 1.02 | 1.08 | 0.95 | 1.39 | 1.63 | 0.25 | 1.36 | 0.94 |
4-guanidinobutanoate | ME364916 | 1.06 | 1.87 | 0.69 | 0.90 | 0.77 | 1.04 | 0.71 | 0.75 | 0.46 | 0.56 | 0.56 | 0.91 | 1.12 | 2.38 | 1.15 | 0.98 | 1.41 | 1.25 |
lanthionine | ME364994 | 0.92 | 1.21 | 0.74 | 0.87 | 0.64 | 0.99 | 0.95 | 1.40 | 0.80 | 0.92 | 0.75 | 1.04 | 1.00 | 2.15 | 1.09 | 0.85 | 0.94 | 0.98 |
ectoine | ME364955 | 1.06 | 1.50 | 0.74 | 0.76 | 0.70 | 0.98 | 0.97 | 1.20 | 0.80 | 0.79 | 0.64 | 0.81 | 1.00 | 1.73 | 1.30 | 0.92 | 1.41 | 0.96 |
methyl indole-3-acetate | ME365001 | 1.20 | 1.35 | 0.91 | 0.63 | 0.66 | 1.04 | 0.96 | 0.87 | 0.88 | 0.62 | 0.94 | 1.11 | 1.01 | 1.58 | 1.00 | 0.89 | 1.30 | 1.27 |
3-phosphoglycerate | ME364914 | 1.21 | 0.69 | 0.83 | 0.80 | 0.56 | 0.99 | 1.94 | 0.55 | 0.55 | 1.27 | 0.72 | 1.35 | 1.11 | 0.78 | 0.78 | 1.28 | 1.11 | 1.36 |
cysteine-glutathione disulfide | ME364948 | 1.19 | 0.64 | 0.63 | 0.97 | 0.58 | 1.02 | 1.89 | 0.53 | 0.62 | 1.72 | 0.51 | 0.89 | 0.97 | 0.97 | 1.00 | 1.63 | 1.08 | 1.09 |
5-(galactosylhydroxy)-L-lysine | ME364917 | 1.06 | 0.88 | 0.91 | 1.13 | 0.75 | 0.80 | 1.54 | 0.97 | 0.82 | 0.99 | 1.06 | 1.40 | 1.08 | 1.14 | 0.66 | 1.18 | 0.59 | 0.91 |
adenosine | ME364922 | 0.64 | 0.91 | 1.00 | 1.14 | 0.79 | 0.77 | 1.90 | 1.00 | 0.91 | 1.30 | 0.77 | 1.14 | 1.11 | 0.68 | 1.04 | 1.14 | 0.69 | 0.82 |
AMP | ME364923 | 1.00 | 0.89 | 0.95 | 1.03 | 0.79 | 0.87 | 1.71 | 0.88 | 0.91 | 1.37 | 0.74 | 1.01 | 0.88 | 0.77 | 0.89 | 1.37 | 0.85 | 0.93 |
gamma-glutamyl-2-aminobutyrate | ME364959 | 1.72 | 0.37 | 0.44 | 0.46 | 0.38 | 1.37 | 1.43 | 0.50 | 0.55 | 0.59 | 0.56 | 1.26 | 1.80 | 1.11 | 1.52 | 1.47 | 1.40 | 1.29 |
2-aminoheptanoate | ME364897 | 1.23 | 0.44 | 0.26 | 0.86 | 0.24 | 1.50 | 1.13 | 0.63 | 0.33 | 0.87 | 0.48 | 1.44 | 1.35 | 1.68 | 1.17 | 1.33 | 1.45 | 1.86 |
gamma-glutamylglutamate | ME364963 | 1.51 | 0.28 | 0.19 | 0.72 | 0.14 | 1.41 | 1.60 | 0.38 | 0.39 | 1.07 | 0.39 | 1.46 | 1.54 | 1.47 | 1.25 | 1.56 | 1.33 | 1.48 |
gamma-glutamylmethionine | ME364968 | 1.40 | 0.37 | 0.44 | 0.45 | 0.50 | 1.37 | 1.39 | 0.38 | 0.67 | 0.58 | 0.69 | 1.33 | 1.45 | 1.44 | 1.54 | 1.18 | 1.46 | 1.64 |
gamma-glutamyl-alpha-lysine | ME364960 | 1.46 | 0.41 | 0.40 | 0.51 | 0.38 | 1.45 | 1.46 | 0.41 | 0.63 | 0.74 | 0.59 | 1.40 | 1.40 | 1.34 | 1.48 | 1.33 | 1.33 | 1.48 |
gamma-glutamylglycine | ME364965 | 1.37 | 0.32 | 0.31 | 0.55 | 0.30 | 1.37 | 1.46 | 0.37 | 0.56 | 0.71 | 0.59 | 1.32 | 1.50 | 1.49 | 1.52 | 1.40 | 1.57 | 1.57 |
gamma-glutamylthreonine | ME364969 | 1.58 | 0.34 | 0.30 | 0.71 | 0.32 | 1.43 | 1.53 | 0.38 | 0.46 | 0.79 | 0.50 | 1.36 | 1.44 | 1.47 | 1.60 | 1.19 | 1.42 | 1.41 |
gamma-glutamyltyrosine | ME364970 | 1.53 | 0.46 | 0.42 | 0.69 | 0.42 | 1.47 | 1.35 | 0.45 | 0.60 | 0.77 | 0.69 | 1.47 | 1.33 | 1.52 | 1.39 | 1.04 | 1.28 | 1.32 |
proline | ME365038 | 1.47 | 0.45 | 0.40 | 0.81 | 0.39 | 1.48 | 1.29 | 0.47 | 0.58 | 0.82 | 0.63 | 1.34 | 1.31 | 1.41 | 1.40 | 1.12 | 1.45 | 1.40 |
threonine | ME365053 | 1.49 | 0.42 | 0.42 | 0.68 | 0.42 | 1.48 | 1.44 | 0.45 | 0.54 | 0.79 | 0.55 | 1.34 | 1.34 | 1.40 | 1.53 | 1.16 | 1.38 | 1.38 |
3-methoxytyrosine | ME364911 | 1.20 | 0.42 | 0.35 | 1.03 | 0.35 | 1.19 | 1.25 | 0.54 | 0.48 | 1.23 | 0.58 | 1.31 | 1.36 | 1.45 | 1.21 | 1.40 | 1.33 | 1.50 |
3-amino-2-piperidone | ME364906 | 1.40 | 0.48 | 0.33 | 1.07 | 0.30 | 1.56 | 1.32 | 0.44 | 0.35 | 0.97 | 0.35 | 1.50 | 1.36 | 1.45 | 1.33 | 1.23 | 1.34 | 1.41 |
ornithine | ME365030 | 1.39 | 0.44 | 0.40 | 0.80 | 0.41 | 1.46 | 1.38 | 0.49 | 0.53 | 0.99 | 0.59 | 1.54 | 1.28 | 1.27 | 1.23 | 1.19 | 1.29 | 1.42 |
cystathionine | ME364944 | 1.21 | 0.84 | 0.82 | 1.09 | 0.72 | 1.36 | 1.07 | 0.63 | 0.70 | 0.94 | 0.63 | 1.10 | 1.24 | 1.47 | 1.33 | 0.75 | 0.97 | 1.37 |
N-acetylarginine | ME365017 | 1.47 | 0.81 | 0.44 | 1.14 | 0.33 | 1.49 | 1.26 | 0.60 | 0.55 | 1.05 | 0.50 | 1.24 | 1.21 | 1.14 | 1.24 | 1.14 | 1.21 | 1.27 |
S-1-pyrroline-5-carboxylate | ME365042 | 1.30 | 0.53 | 0.41 | 1.22 | 0.48 | 1.21 | 1.27 | 0.49 | 0.63 | 0.94 | 0.63 | 1.21 | 1.29 | 1.23 | 1.32 | 1.05 | 1.67 | 1.26 |
gamma-glutamylhistidine | ME364966 | 1.30 | 0.70 | 0.52 | 0.58 | 0.46 | 1.23 | 1.58 | 0.64 | 0.93 | 0.85 | 0.81 | 1.47 | 1.30 | 1.12 | 1.20 | 1.40 | 0.97 | 0.98 |
hydroxyproline | ME365055 | 1.27 | 0.64 | 0.55 | 0.71 | 0.64 | 1.12 | 1.23 | 0.69 | 0.80 | 0.80 | 0.97 | 1.14 | 1.17 | 1.19 | 1.29 | 1.02 | 1.71 | 1.20 |
gamma-glutamylcitrulline* | ME364961 | 1.31 | 0.59 | 0.42 | 0.48 | 0.37 | 1.19 | 1.43 | 0.63 | 0.70 | 0.66 | 0.66 | 1.38 | 1.45 | 1.51 | 1.35 | 1.28 | 1.39 | 1.43 |
gamma-glutamylisoleucine* | ME364967 | 1.24 | 0.75 | 0.55 | 0.60 | 0.48 | 1.22 | 1.19 | 0.69 | 0.77 | 0.65 | 0.72 | 1.17 | 1.36 | 1.58 | 1.41 | 1.18 | 1.34 | 1.35 |
gamma-glutamylvaline | ME364971 | 1.21 | 0.71 | 0.49 | 0.68 | 0.43 | 1.18 | 1.22 | 0.82 | 0.75 | 0.87 | 0.69 | 1.21 | 1.29 | 1.45 | 1.36 | 1.25 | 1.26 | 1.29 |
alanine | ME364925 | 1.34 | 0.57 | 0.54 | 0.88 | 0.59 | 1.26 | 1.32 | 0.57 | 0.68 | 0.81 | 0.69 | 1.29 | 1.25 | 1.36 | 1.47 | 0.99 | 1.29 | 1.29 |
glycine | ME364979 | 1.24 | 0.46 | 0.49 | 0.68 | 0.53 | 1.25 | 1.31 | 0.54 | 0.73 | 0.80 | 0.76 | 1.24 | 1.34 | 1.33 | 1.35 | 1.24 | 1.46 | 1.42 |
arginine | ME364928 | 1.29 | 0.56 | 0.56 | 0.73 | 0.54 | 1.34 | 1.31 | 0.58 | 0.70 | 0.86 | 0.69 | 1.37 | 1.23 | 1.21 | 1.28 | 1.21 | 1.32 | 1.33 |
gamma-glutamylglutamine | ME364964 | 1.41 | 0.62 | 0.54 | 0.67 | 0.50 | 1.32 | 1.36 | 0.62 | 0.77 | 0.75 | 0.67 | 1.36 | 1.28 | 1.25 | 1.22 | 1.22 | 1.23 | 1.32 |
methionine sulfoxide | ME365000 | 1.25 | 0.68 | 0.70 | 0.60 | 0.71 | 1.31 | 1.15 | 0.72 | 0.90 | 0.69 | 0.90 | 1.21 | 1.13 | 1.26 | 1.25 | 0.95 | 1.23 | 1.48 |
citrulline | ME364939 | 1.13 | 0.74 | 0.61 | 0.66 | 0.54 | 1.16 | 1.26 | 0.81 | 0.88 | 0.83 | 0.78 | 1.25 | 1.25 | 1.31 | 1.21 | 1.13 | 1.29 | 1.25 |
tyrosine | ME365061 | 1.35 | 0.73 | 0.69 | 0.74 | 0.66 | 1.25 | 1.27 | 0.67 | 0.81 | 0.83 | 0.84 | 1.19 | 1.18 | 1.31 | 1.18 | 1.02 | 1.26 | 1.16 |
asparagine | ME364929 | 1.25 | 0.60 | 0.68 | 0.61 | 0.67 | 1.20 | 1.33 | 0.67 | 0.95 | 0.76 | 0.88 | 1.25 | 1.21 | 1.22 | 1.25 | 1.09 | 1.23 | 1.24 |
methionine | ME364998 | 1.33 | 0.58 | 0.72 | 0.62 | 0.73 | 1.25 | 1.24 | 0.61 | 0.85 | 0.73 | 0.87 | 1.18 | 1.24 | 1.24 | 1.30 | 1.11 | 1.27 | 1.28 |
glutamine | ME364973 | 1.24 | 0.72 | 0.64 | 0.73 | 0.57 | 1.29 | 1.25 | 0.74 | 0.85 | 0.83 | 0.79 | 1.28 | 1.15 | 1.21 | 1.18 | 1.17 | 1.21 | 1.24 |
lysine | ME364997 | 1.26 | 0.66 | 0.66 | 0.71 | 0.65 | 1.22 | 1.26 | 0.68 | 0.87 | 0.81 | 0.87 | 1.23 | 1.20 | 1.11 | 1.29 | 1.17 | 1.19 | 1.25 |
2-aminobutyrate | ME364896 | 1.28 | 0.59 | 0.54 | 0.71 | 0.57 | 1.13 | 1.35 | 0.67 | 0.83 | 0.91 | 0.84 | 1.13 | 1.23 | 1.28 | 1.27 | 1.33 | 1.23 | 1.23 |
serine | ME365044 | 1.15 | 0.53 | 0.62 | 0.63 | 0.63 | 1.18 | 1.39 | 0.64 | 0.88 | 0.83 | 0.91 | 1.26 | 1.25 | 1.12 | 1.19 | 1.22 | 1.33 | 1.29 |
gamma-glutamyl-epsilon-lysine | ME364962 | 1.29 | 0.58 | 0.55 | 0.77 | 0.49 | 0.99 | 1.60 | 0.67 | 0.79 | 0.72 | 0.85 | 1.34 | 1.32 | 1.06 | 1.22 | 1.38 | 1.30 | 1.11 |
hydroxy-N6,N6,N6-trimethyllysine* | ME364986 | 1.20 | 0.68 | 0.61 | 0.78 | 0.46 | 1.05 | 1.44 | 0.64 | 0.71 | 0.88 | 0.71 | 1.32 | 1.33 | 1.42 | 1.26 | 1.21 | 1.36 | 1.09 |
creatine | ME364941 | 1.27 | 1.02 | 0.69 | 1.17 | 0.54 | 1.12 | 1.24 | 0.93 | 0.74 | 1.22 | 0.65 | 1.10 | 1.11 | 0.98 | 1.05 | 1.15 | 0.98 | 1.01 |
butyrylcarnitine (C4) | ME364933 | 1.41 | 0.77 | 0.70 | 0.91 | 0.77 | 1.24 | 1.32 | 0.76 | 0.85 | 1.00 | 0.80 | 1.32 | 1.09 | 1.05 | 1.04 | 0.98 | 0.99 | 0.99 |
homostachydrine* | ME364983 | 1.46 | 0.72 | 0.74 | 1.10 | 0.63 | 1.18 | 1.34 | 0.75 | 0.82 | 1.10 | 0.73 | 1.44 | 1.12 | 0.90 | 1.00 | 0.99 | 0.97 | 0.95 |
cysteine sulfinic acid | ME364947 | 1.19 | 0.67 | 0.65 | 0.96 | 0.66 | 1.26 | 1.20 | 0.64 | 0.76 | 1.21 | 0.69 | 1.22 | 0.87 | 1.26 | 0.99 | 1.30 | 1.12 | 1.40 |
cystine | ME364951 | 1.18 | 0.52 | 0.55 | 0.90 | 0.54 | 1.16 | 1.14 | 0.73 | 0.81 | 1.17 | 0.74 | 1.43 | 1.09 | 1.10 | 1.28 | 1.12 | 1.19 | 1.40 |
glutamate | ME364972 | 1.23 | 0.61 | 0.56 | 0.99 | 0.49 | 1.23 | 1.36 | 0.70 | 0.69 | 1.22 | 0.62 | 1.35 | 1.32 | 1.10 | 1.00 | 1.21 | 1.10 | 1.23 |
stachydrine | ME365048 | 1.22 | 0.59 | 0.59 | 0.87 | 0.68 | 1.39 | 1.32 | 0.62 | 0.75 | 1.01 | 0.93 | 1.53 | 1.09 | 0.83 | 0.88 | 1.02 | 1.30 | 1.30 |
trimethylamine N-oxide | ME365058 | 1.21 | 0.52 | 0.83 | 0.94 | 0.65 | 1.32 | 1.01 | 0.61 | 1.00 | 0.96 | 0.83 | 1.42 | 1.10 | 1.00 | 1.09 | 1.11 | 1.13 | 1.31 |
N1-Methyl-4-pyridone-3-carboxamide | ME365005 | 1.04 | 1.32 | 0.60 | 1.04 | 0.52 | 1.12 | 1.03 | 1.34 | 0.66 | 1.10 | 0.64 | 1.04 | 0.97 | 1.07 | 1.31 | 0.94 | 0.82 | 1.45 |
2-oxoarginine* | ME364902 | 1.22 | 1.59 | 0.90 | 1.76 | 0.62 | 1.18 | 0.88 | 0.94 | 0.64 | 0.97 | 0.48 | 0.92 | 0.95 | 1.36 | 1.10 | 0.61 | 0.92 | 1.08 |
indolin-2-one | ME364989 | 1.59 | 1.29 | 0.72 | 1.25 | 0.57 | 1.16 | 0.83 | 1.04 | 0.56 | 0.96 | 0.51 | 0.87 | 1.08 | 1.48 | 0.94 | 1.00 | 0.95 | 1.39 |
formiminoglutamate | ME364957 | 1.04 | 0.95 | 0.67 | 1.53 | 0.62 | 0.95 | 0.97 | 0.80 | 0.67 | 1.26 | 0.65 | 0.99 | 1.21 | 1.50 | 1.03 | 1.22 | 0.97 | 1.14 |
succinylcarnitine (C4) | ME365049 | 1.04 | 0.76 | 0.53 | 1.41 | 0.47 | 1.18 | 1.14 | 0.60 | 0.52 | 1.40 | 0.65 | 1.13 | 1.16 | 1.26 | 1.15 | 1.27 | 1.22 | 1.20 |
3-methylglutarylcarnitine (2) | ME364912 | 0.81 | 0.77 | 0.51 | 0.87 | 0.35 | 0.79 | 1.34 | 1.06 | 0.86 | 1.35 | 0.69 | 1.40 | 1.13 | 1.09 | 1.21 | 1.13 | 1.31 | 1.32 |
N-acetylglucosaminylasparagine | ME365020 | 1.02 | 0.71 | 0.62 | 1.04 | 0.53 | 0.92 | 1.38 | 1.03 | 0.77 | 1.36 | 0.99 | 1.24 | 0.95 | 1.05 | 0.87 | 1.35 | 1.14 | 0.91 |
1-methyl-5-imidazoleacetate | ME364892 | 0.86 | 1.36 | 0.93 | 0.85 | 1.34 | 1.26 | 0.68 | 1.21 | 0.72 | 0.69 | 0.96 | 1.18 | 1.04 | 1.09 | 0.77 | 0.82 | 0.97 | 1.32 |
2-pyrrolidinone | ME364904 | 1.07 | 1.21 | 0.76 | 1.06 | 0.75 | 0.78 | 1.16 | 0.72 | 0.83 | 1.02 | 0.88 | 0.94 | 1.08 | 1.19 | 1.12 | 1.27 | 1.33 | 0.95 |
ergothioneine | ME364956 | 0.99 | 0.83 | 0.77 | 0.77 | 0.74 | 0.91 | 1.25 | 0.85 | 0.85 | 0.98 | 0.77 | 1.00 | 1.11 | 1.13 | 1.15 | 1.34 | 1.21 | 1.45 |
methionine sulfone | ME364999 | 0.98 | 0.66 | 0.71 | 0.60 | 0.63 | 0.87 | 1.23 | 0.86 | 1.03 | 0.91 | 0.88 | 1.19 | 1.27 | 1.32 | 1.15 | 1.30 | 1.26 | 1.26 |
1-methylnicotinamide | ME364894 | 1.11 | 0.83 | 0.78 | 0.92 | 0.73 | 0.90 | 1.15 | 0.99 | 1.00 | 0.91 | 0.92 | 1.46 | 1.03 | 1.39 | 1.09 | 0.83 | 0.83 | 1.18 |
fructosyllysine | ME364958 | 1.17 | 0.79 | 0.72 | 0.71 | 0.69 | 1.05 | 1.32 | 0.84 | 1.02 | 0.83 | 0.86 | 1.37 | 1.09 | 1.15 | 1.12 | 0.89 | 1.20 | 1.20 |
prolylhydroxyproline | ME365037 | 1.04 | 0.75 | 0.69 | 0.64 | 0.71 | 1.00 | 1.32 | 0.92 | 1.10 | 0.97 | 1.17 | 1.24 | 1.09 | 1.03 | 1.15 | 1.02 | 1.07 | 1.05 |
dimethylglycine | ME364954 | 0.93 | 0.86 | 0.70 | 1.03 | 0.64 | 1.01 | 1.13 | 0.93 | 0.94 | 1.19 | 0.92 | 1.24 | 1.04 | 1.08 | 0.96 | 1.03 | 1.13 | 1.21 |
N-acetylcarnosine | ME365018 | 1.08 | 0.95 | 0.81 | 1.19 | 0.77 | 1.07 | 1.07 | 1.00 | 0.91 | 1.20 | 0.81 | 1.20 | 0.91 | 1.18 | 1.01 | 0.88 | 0.94 | 1.00 |
iminodiacetate (IDA) | ME364988 | 0.96 | 0.95 | 0.96 | 0.88 | 0.99 | 0.97 | 1.02 | 0.97 | 1.04 | 1.04 | 1.13 | 1.00 | 0.92 | 1.15 | 1.02 | 1.04 | 1.06 | 0.92 |
sarcosine | ME365043 | 0.97 | 0.91 | 0.84 | 0.81 | 0.94 | 1.02 | 1.10 | 0.88 | 1.03 | 1.07 | 1.19 | 1.08 | 0.98 | 1.20 | 1.01 | 1.06 | 0.95 | 0.96 |
urea | ME365062 | 1.02 | 1.10 | 0.92 | 0.97 | 0.84 | 0.90 | 1.05 | 1.10 | 0.97 | 1.02 | 0.97 | 0.95 | 1.03 | 1.10 | 1.08 | 0.97 | 1.05 | 0.98 |
pyridoxal | ME365040 | 0.95 | 1.04 | 1.04 | 0.99 | 1.00 | 0.99 | 1.03 | 0.97 | 0.96 | 1.00 | 1.02 | 0.97 | 1.00 | 0.96 | 1.05 | 1.10 | 0.99 | 0.94 |
creatinine | ME364942 | 1.03 | 0.97 | 0.96 | 0.96 | 0.95 | 1.02 | 0.94 | 0.87 | 0.93 | 0.91 | 0.89 | 0.97 | 1.12 | 1.14 | 1.12 | 1.10 | 1.14 | 1.10 |
N1-methylinosine | ME365007 | 1.01 | 0.95 | 0.98 | 0.91 | 1.00 | 0.92 | 1.01 | 0.89 | 0.99 | 0.96 | 0.93 | 0.97 | 1.11 | 1.22 | 1.04 | 1.02 | 1.14 | 1.06 |
tryptophan | ME365059 | 1.11 | 0.98 | 0.95 | 0.92 | 0.92 | 1.07 | 1.02 | 0.99 | 0.97 | 0.97 | 0.94 | 1.04 | 1.01 | 1.01 | 1.09 | 0.94 | 1.03 | 1.03 |
N2,N2-dimethylguanosine | ME365008 | 1.04 | 0.92 | 0.94 | 0.90 | 0.89 | 1.00 | 1.04 | 0.90 | 1.01 | 0.97 | 0.99 | 1.06 | 1.06 | 1.08 | 1.00 | 1.07 | 1.11 | 1.04 |
5-methylthioadenosine (MTA) | ME364918 | 1.03 | 1.05 | 1.00 | 0.95 | 0.95 | 0.97 | 1.05 | 0.98 | 0.97 | 0.91 | 0.94 | 1.04 | 1.08 | 1.06 | 1.05 | 0.96 | 1.05 | 1.01 |
1-methyladenosine | ME365006 | 0.98 | 1.04 | 1.00 | 0.95 | 0.94 | 1.00 | 0.97 | 0.93 | 0.99 | 1.00 | 0.96 | 0.98 | 1.05 | 1.13 | 1.03 | 1.02 | 1.06 | 1.05 |
7-methylguanine | ME364919 | 1.01 | 1.00 | 0.98 | 0.96 | 0.91 | 0.96 | 1.03 | 0.97 | 0.97 | 1.01 | 0.97 | 0.99 | 1.03 | 1.02 | 1.04 | 1.06 | 1.05 | 1.06 |
cysteine | ME364945 | 1.02 | 0.82 | 0.87 | 1.00 | 0.76 | 1.05 | 0.99 | 0.96 | 0.90 | 1.01 | 0.97 | 0.97 | 1.08 | 1.23 | 1.17 | 1.17 | 1.08 | 1.05 |
thioproline | ME365052 | 0.98 | 0.84 | 0.86 | 1.03 | 0.84 | 1.03 | 1.04 | 0.94 | 0.91 | 1.09 | 0.98 | 1.05 | 1.06 | 1.14 | 1.12 | 1.14 | 1.01 | 0.95 |
imidazole lactate | ME364987 | 1.02 | 0.93 | 0.88 | 0.97 | 0.89 | 0.95 | 1.13 | 0.95 | 0.96 | 1.04 | 0.98 | 1.09 | 1.10 | 1.04 | 1.00 | 1.08 | 0.98 | 1.01 |
N-acetylglucosamine/N-acetylgalactosamine | ME365019 | 1.01 | 0.93 | 0.83 | 1.02 | 0.87 | 0.92 | 1.14 | 0.92 | 0.93 | 1.15 | 0.96 | 0.98 | 1.02 | 1.05 | 0.95 | 1.20 | 1.07 | 1.04 |
cysteinylglycine disulfide* | ME364950 | 1.08 | 0.80 | 0.86 | 0.92 | 0.85 | 1.02 | 1.15 | 0.87 | 0.93 | 1.05 | 0.90 | 1.10 | 1.10 | 1.05 | 1.09 | 1.09 | 1.03 | 1.12 |
N-acetyl-isoputreanine | ME365021 | 1.07 | 0.90 | 0.93 | 0.94 | 0.89 | 0.96 | 1.09 | 0.69 | 0.94 | 1.07 | 0.99 | 1.08 | 1.13 | 1.02 | 1.05 | 1.13 | 1.14 | 1.03 |
beta-alanine | ME364931 | 1.15 | 1.07 | 0.99 | 0.88 | 0.93 | 1.17 | 0.95 | 0.92 | 0.81 | 0.83 | 0.79 | 1.11 | 1.14 | 1.11 | 1.14 | 0.96 | 0.98 | 1.17 |
1-methyl-4-imidazoleacetate | ME364891 | 0.98 | 1.00 | 0.89 | 1.01 | 0.98 | 1.07 | 0.93 | 0.93 | 0.81 | 0.89 | 0.85 | 1.04 | 1.13 | 1.23 | 1.00 | 1.13 | 1.05 | 1.20 |
1-ribosyl-imidazoleacetate* | ME364895 | 1.01 | 1.05 | 0.78 | 0.94 | 0.89 | 1.08 | 0.98 | 0.95 | 0.83 | 0.86 | 0.90 | 1.12 | 1.11 | 1.39 | 1.08 | 1.00 | 1.07 | 1.11 |
2-methylbutyrylcarnitine (C5) | ME364898 | 1.12 | 1.03 | 0.85 | 0.69 | 0.85 | 1.13 | 1.03 | 0.94 | 1.02 | 0.72 | 0.98 | 1.09 | 1.12 | 1.30 | 1.08 | 0.94 | 1.05 | 1.17 |
isoleucine | ME364991 | 1.11 | 1.06 | 0.89 | 0.65 | 0.85 | 1.05 | 1.03 | 0.99 | 1.01 | 0.72 | 0.96 | 0.98 | 1.13 | 1.21 | 1.18 | 1.04 | 1.12 | 1.16 |
leucine | ME364995 | 1.09 | 0.97 | 0.82 | 0.66 | 0.79 | 1.07 | 1.08 | 0.95 | 1.05 | 0.75 | 0.98 | 1.07 | 1.11 | 1.17 | 1.14 | 1.08 | 1.13 | 1.15 |
N6-methyllysine | ME365013 | 1.10 | 0.89 | 0.83 | 0.74 | 0.68 | 1.02 | 1.14 | 1.02 | 0.87 | 0.96 | 1.00 | 1.18 | 1.14 | 1.15 | 1.07 | 1.12 | 1.05 | 1.08 |
betaine | ME364932 | 1.07 | 0.98 | 0.86 | 0.80 | 0.95 | 1.24 | 1.08 | 0.93 | 0.95 | 0.89 | 0.97 | 1.23 | 0.97 | 0.96 | 0.93 | 0.99 | 1.02 | 1.15 |
choline | ME364937 | 1.01 | 0.96 | 0.84 | 0.85 | 0.81 | 1.09 | 1.07 | 0.97 | 0.99 | 0.92 | 0.94 | 1.17 | 1.06 | 1.09 | 0.95 | 1.12 | 1.03 | 1.14 |
phenylalanine | ME365032 | 1.07 | 0.94 | 0.93 | 0.73 | 0.90 | 1.09 | 1.08 | 0.99 | 1.04 | 0.86 | 1.00 | 1.07 | 1.06 | 1.09 | 1.08 | 0.99 | 1.05 | 1.07 |
N-acetylputrescine | ME365023 | 1.06 | 1.18 | 0.73 | 1.14 | 0.73 | 1.13 | 0.96 | 0.82 | 0.73 | 1.01 | 0.74 | 1.05 | 1.14 | 1.09 | 1.09 | 1.10 | 1.17 | 1.23 |
cysteine s-sulfate | ME364946 | 1.29 | 0.70 | 0.78 | 0.92 | 0.73 | 1.27 | 1.21 | 0.81 | 0.71 | 0.87 | 1.02 | 1.17 | 1.29 | 1.04 | 1.03 | 0.93 | 1.02 | 1.24 |
homoarginine | ME364982 | 1.23 | 0.97 | 0.87 | 0.83 | 0.68 | 1.31 | 1.13 | 0.77 | 0.75 | 0.83 | 0.62 | 1.20 | 1.15 | 1.18 | 1.12 | 1.17 | 1.19 | 1.13 |
dimethylarginine (ADMA + SDMA) | ME364953 | 1.16 | 0.75 | 0.78 | 0.74 | 0.74 | 1.18 | 1.19 | 0.76 | 0.90 | 0.86 | 0.90 | 1.24 | 1.15 | 1.07 | 1.11 | 1.17 | 1.16 | 1.19 |
hydroxyasparagine | ME364984 | 1.06 | 0.75 | 0.70 | 0.87 | 0.67 | 1.09 | 1.16 | 0.86 | 0.92 | 1.00 | 0.88 | 1.25 | 1.14 | 1.12 | 1.13 | 1.10 | 1.14 | 1.18 |
N,N,N-trimethyl-5-aminovalerate | ME365002 | 1.12 | 0.74 | 0.69 | 0.86 | 0.65 | 1.09 | 1.26 | 0.80 | 0.86 | 1.08 | 0.84 | 1.18 | 1.16 | 1.09 | 1.15 | 1.13 | 1.21 | 1.14 |
carnitine | ME364936 | 1.15 | 0.88 | 0.78 | 1.03 | 0.75 | 1.17 | 1.10 | 0.83 | 0.84 | 1.06 | 0.80 | 1.12 | 1.08 | 1.07 | 1.10 | 1.06 | 1.15 | 1.06 |
propionylcarnitine (C3) | ME365039 | 1.27 | 0.92 | 0.75 | 0.98 | 0.66 | 1.24 | 1.18 | 0.83 | 0.82 | 0.99 | 0.77 | 1.17 | 1.06 | 1.08 | 1.12 | 0.91 | 1.12 | 1.12 |
glutaroylcarnitine (C5) | ME364976 | 1.02 | 0.94 | 0.85 | 0.94 | 0.77 | 1.06 | 1.16 | 0.87 | 0.88 | 1.01 | 0.86 | 1.11 | 1.09 | 1.25 | 1.10 | 0.99 | 1.10 | 1.08 |
deoxycarnitine | ME364952 | 1.17 | 0.90 | 0.81 | 0.87 | 0.79 | 1.08 | 1.09 | 0.81 | 0.84 | 0.91 | 0.82 | 1.07 | 1.13 | 1.20 | 1.19 | 1.10 | 1.20 | 1.13 |
valine | ME365063 | 1.13 | 0.94 | 0.75 | 0.85 | 0.67 | 1.10 | 1.11 | 0.93 | 0.95 | 0.88 | 0.83 | 1.07 | 1.15 | 1.23 | 1.18 | 1.08 | 1.14 | 1.10 |
1-methylhistidine | ME364893 | 1.23 | 0.76 | 0.80 | 0.82 | 0.71 | 0.98 | 1.15 | 0.74 | 0.80 | 0.83 | 0.81 | 1.14 | 1.20 | 1.40 | 1.14 | 1.37 | 1.36 | 0.93 |
2^-O-methylcytidine | ME364901 | 1.15 | 0.94 | 0.94 | 0.86 | 0.97 | 1.10 | 0.95 | 0.73 | 0.92 | 0.81 | 0.85 | 0.93 | 1.13 | 1.18 | 1.19 | 1.18 | 1.25 | 1.09 |
pyroglutamine* | ME365041 | 1.25 | 0.94 | 0.94 | 0.99 | 0.89 | 1.14 | 0.92 | 0.74 | 0.74 | 0.78 | 0.72 | 0.89 | 1.24 | 1.34 | 1.27 | 1.09 | 1.18 | 1.18 |
N-acetyltryptophan | ME365024 | 0.89 | 0.83 | 0.83 | 0.96 | 0.71 | 1.01 | 0.86 | 0.98 | 0.77 | 0.91 | 0.79 | 1.15 | 1.21 | 1.55 | 1.26 | 0.93 | 1.17 | 1.40 |
N6,N6,N6-trimethyllysine | ME365011 | 1.07 | 0.95 | 0.75 | 0.64 | 0.65 | 1.21 | 1.05 | 0.93 | 0.88 | 0.72 | 0.70 | 1.15 | 1.20 | 1.53 | 1.28 | 1.04 | 1.15 | 1.30 |
N6,N6-dimethyllysine | ME365012 | 1.04 | 0.90 | 0.82 | 0.73 | 0.65 | 1.05 | 1.00 | 0.86 | 0.87 | 0.81 | 0.87 | 1.04 | 1.22 | 1.41 | 1.24 | 1.23 | 1.22 | 1.24 |
N,N,N-trimethyl-alanylproline betaine (TMAP) | ME365003 | 1.08 | 0.92 | 0.77 | 0.89 | 0.82 | 1.03 | 1.03 | 0.84 | 0.78 | 0.88 | 0.79 | 1.05 | 1.18 | 1.38 | 1.18 | 1.14 | 1.21 | 1.21 |
3-formylindole | ME364908 | 0.85 | 1.35 | 1.27 | 1.05 | 1.24 | 0.87 | 0.83 | 1.40 | 1.12 | 1.04 | 1.11 | 0.90 | 0.79 | 0.92 | 0.84 | 0.69 | 0.81 | 0.82 |
kynurenine | ME364993 | 0.86 | 1.13 | 1.07 | 0.97 | 0.94 | 0.87 | 0.95 | 1.25 | 1.12 | 1.06 | 1.06 | 1.01 | 0.95 | 0.95 | 0.97 | 0.84 | 0.95 | 0.99 |
N-methylpipecolate | ME365028 | 0.97 | 1.26 | 1.09 | 0.94 | 1.02 | 0.78 | 1.31 | 1.19 | 1.06 | 1.04 | 1.04 | 1.13 | 0.89 | 0.98 | 0.77 | 0.83 | 0.81 | 0.75 |
N4-acetylcytidine | ME365010 | 0.92 | 1.06 | 1.17 | 1.16 | 1.09 | 1.14 | 0.80 | 0.98 | 0.95 | 1.17 | 1.10 | 0.92 | 0.95 | 1.00 | 0.87 | 1.04 | 0.83 | 0.84 |
trans-urocanate | ME365056 | 0.98 | 1.09 | 0.86 | 1.28 | 0.75 | 1.23 | 0.90 | 0.92 | 0.87 | 1.23 | 1.02 | 1.14 | 0.79 | 0.87 | 1.07 | 1.16 | 0.85 | 0.93 |
carboxyethyl-GABA | ME364935 | 0.98 | 0.95 | 1.02 | 0.90 | 0.94 | 0.97 | 1.30 | 0.85 | 0.94 | 1.23 | 0.82 | 0.99 | 1.11 | 1.00 | 1.16 | 1.05 | 0.80 | 1.00 |
spermidine | ME365047 | 1.14 | 0.97 | 1.08 | 1.09 | 1.00 | 0.96 | 1.28 | 0.73 | 0.88 | 1.35 | 0.74 | 0.88 | 0.94 | 0.86 | 0.94 | 1.21 | 0.91 | 1.01 |
hydroxy-CMPF* | ME364985 | 1.19 | 1.10 | 1.32 | 1.20 | 1.19 | 1.14 | 0.90 | 0.90 | 0.92 | 0.89 | 0.67 | 0.85 | 0.99 | 0.89 | 1.02 | 0.96 | 0.96 | 0.96 |
serotonin | ME365045 | 1.02 | 1.02 | 1.08 | 1.24 | 1.04 | 0.81 | 0.90 | 1.20 | 1.06 | 1.31 | 0.75 | 1.03 | 0.98 | 0.80 | 0.93 | 0.81 | 0.96 | 0.98 |
N-acetylneuraminate | ME365022 | 1.07 | 1.02 | 1.00 | 1.12 | 1.07 | 1.19 | 1.01 | 0.87 | 0.92 | 1.08 | 0.64 | 1.11 | 1.16 | 0.84 | 1.01 | 0.90 | 0.96 | 1.01 |
glycerophosphoethanolamine | ME364977 | 1.04 | 1.04 | 1.03 | 1.21 | 0.92 | 1.01 | 0.98 | 0.98 | 0.96 | 1.14 | 0.78 | 1.01 | 0.97 | 0.91 | 1.01 | 0.94 | 1.00 | 1.03 |
glycerophosphorylcholine (GPC) | ME364978 | 1.06 | 0.98 | 0.96 | 1.10 | 0.88 | 0.92 | 0.94 | 0.99 | 0.95 | 1.08 | 0.81 | 1.00 | 1.03 | 1.02 | 1.11 | 0.97 | 1.12 | 1.10 |
nicotinamide | ME365025 | 1.04 | 1.00 | 1.09 | 1.13 | 0.96 | 0.93 | 1.22 | 0.99 | 1.05 | 1.22 | 0.84 | 1.05 | 0.93 | 0.95 | 0.90 | 0.82 | 0.82 | 0.97 |
phosphocholine | ME364938 | 1.24 | 1.26 | 1.22 | 1.35 | 1.08 | 1.00 | 1.00 | 0.94 | 0.96 | 1.02 | 0.79 | 0.96 | 0.97 | 0.83 | 0.88 | 0.78 | 0.86 | 0.81 |
phosphoethanolamine (PE) | ME365034 | 1.18 | 1.10 | 1.13 | 1.23 | 0.97 | 0.96 | 1.06 | 1.00 | 1.05 | 1.01 | 0.84 | 1.01 | 1.03 | 0.82 | 0.95 | 0.82 | 0.88 | 0.87 |
taurine | ME365050 | 1.15 | 1.03 | 1.11 | 1.16 | 1.00 | 1.03 | 1.01 | 0.94 | 1.02 | 0.98 | 0.84 | 1.02 | 1.02 | 0.91 | 0.98 | 0.88 | 0.96 | 0.95 |
N-methylalanine | ME365026 | 1.19 | 1.17 | 1.37 | 0.91 | 1.04 | 0.69 | 0.90 | 1.00 | 0.85 | 0.80 | 1.01 | 0.82 | 0.92 | 1.22 | 1.16 | 1.11 | 1.20 | 0.81 |
isovalerylcarnitine (C5) | ME364992 | 1.12 | 1.34 | 1.12 | 0.79 | 0.98 | 1.17 | 0.96 | 1.01 | 1.04 | 0.83 | 1.08 | 1.08 | 0.87 | 0.95 | 0.98 | 0.94 | 0.83 | 0.90 |
isobutyrylcarnitine (C4) | ME364990 | 1.05 | 0.96 | 1.19 | 0.83 | 1.15 | 0.93 | 1.02 | 0.91 | 1.14 | 0.76 | 0.98 | 0.99 | 1.02 | 1.28 | 1.11 | 0.83 | 0.87 | 1.09 |
tiglyl carnitine (C5) | ME365054 | 1.02 | 1.02 | 1.09 | 0.65 | 1.01 | 0.96 | 1.04 | 0.82 | 1.13 | 0.71 | 1.18 | 0.96 | 0.99 | 1.24 | 1.09 | 1.06 | 1.12 | 1.04 |
cysteinylglycine | ME364949 | 1.03 | 1.21 | 1.20 | 1.07 | 1.08 | 1.00 | 0.87 | 1.03 | 0.92 | 0.81 | 0.98 | 0.76 | 1.04 | 1.23 | 1.08 | 0.96 | 0.93 | 0.92 |
adenine | ME364921 | 1.14 | 1.10 | 1.01 | 1.17 | 1.03 | 1.00 | 0.92 | 0.85 | 1.00 | 0.91 | 1.03 | 0.97 | 0.97 | 0.85 | 1.16 | 1.03 | 0.87 | 1.02 |
adipoylcarnitine (C6-DC) | ME364924 | 1.01 | 1.05 | 1.19 | 0.97 | 1.17 | 1.02 | 0.90 | 0.87 | 0.98 | 0.88 | 1.09 | 0.85 | 1.01 | 0.96 | 0.93 | 1.17 | 0.97 | 1.05 |
(N(1) + N(8))-acetylspermidine | ME364888 | 1.04 | 1.03 | 1.17 | 1.00 | 1.14 | 1.01 | 0.91 | 0.86 | 1.01 | 0.90 | 1.06 | 0.97 | 0.94 | 1.02 | 0.96 | 0.95 | 1.02 | 1.05 |
cys-gly, oxidized | ME364943 | 0.98 | 1.06 | 1.05 | 0.84 | 1.14 | 0.96 | 1.14 | 0.98 | 1.06 | 0.84 | 1.04 | 0.86 | 1.06 | 1.11 | 0.96 | 0.99 | 0.93 | 1.03 |
phosphate | ME365033 | 1.11 | 1.03 | 0.92 | 0.86 | 1.06 | 1.06 | 1.01 | 1.04 | 1.00 | 0.85 | 1.03 | 0.96 | 1.01 | 1.00 | 1.08 | 1.01 | 0.94 | 1.05 |
glutamine conjugate of C6H10O2 (1)* | ME364974 | 0.77 | 1.28 | 1.22 | 0.30 | 1.09 | 0.93 | 0.95 | 0.81 | 1.00 | 0.44 | 1.30 | 1.14 | 1.18 | 1.07 | 0.97 | 1.47 | 1.20 | 1.03 |
acetylcarnitine (C2) | ME364920 | 0.98 | 1.34 | 1.10 | 0.53 | 1.13 | 0.85 | 1.01 | 1.18 | 1.16 | 0.67 | 1.13 | 0.94 | 1.03 | 0.88 | 0.82 | 1.36 | 0.98 | 0.90 |
3-hydroxyhexanoylcarnitine (1) | ME364909 | 1.01 | 1.18 | 1.13 | 0.74 | 1.27 | 1.01 | 0.91 | 0.83 | 0.82 | 0.75 | 1.23 | 0.84 | 1.06 | 0.97 | 0.80 | 1.53 | 1.12 | 0.90 |
(S)-3-hydroxybutyrylcarnitine | ME364890 | 0.98 | 1.49 | 1.27 | 0.53 | 1.34 | 1.01 | 0.92 | 0.88 | 1.00 | 0.57 | 1.12 | 0.81 | 1.02 | 0.91 | 0.83 | 1.54 | 1.01 | 0.87 |
3-aminoisobutyrate | ME364907 | 0.88 | 0.89 | 1.02 | 0.56 | 0.86 | 0.78 | 1.06 | 1.07 | 1.22 | 0.78 | 1.16 | 0.98 | 1.12 | 1.09 | 0.90 | 1.39 | 1.16 | 1.11 |
hexanoylcarnitine (C6) | ME364980 | 1.16 | 0.82 | 0.71 | 0.45 | 0.75 | 1.01 | 1.53 | 0.88 | 1.05 | 0.74 | 1.08 | 1.02 | 1.23 | 0.95 | 1.01 | 1.44 | 1.13 | 1.01 |
caffeine | ME364934 | 1.36 | 1.44 | 0.93 | 0.94 | 0.71 | 2.08 | 0.56 | 0.56 | 0.56 | 0.56 | 0.56 | 0.96 | 0.86 | 0.56 | 0.56 | 0.73 | 0.56 | 3.55 |
N-acetyl-3-methylhistidine* | ME365015 | 1.13 | 1.30 | 0.72 | 0.90 | 0.67 | 2.51 | 0.85 | 1.17 | 0.46 | 0.62 | 0.63 | 1.26 | 0.85 | 0.84 | 0.57 | 0.80 | 0.86 | 1.73 |
Factors:
F1 | Group:High-Dose | TIMEPOINT:-0.5HR |
F2 | Group:High-Dose | TIMEPOINT:+23HR POST INFUSION |
F3 | Group:High-Dose | TIMEPOINT:+47HR POST INFUSION |
F4 | Group:High-Dose | TIMEPOINT:+4HR POST INFUSION |
F5 | Group:High-Dose | TIMEPOINT:+71HR POST INFUSION |
F6 | Group:High-Dose | TIMEPOINT:BASELINE |
F7 | Group:Low-Dose | TIMEPOINT:-0.5HR |
F8 | Group:Low-Dose | TIMEPOINT:+23HR POST INFUSION |
F9 | Group:Low-Dose | TIMEPOINT:+47HR POST INFUSION |
F10 | Group:Low-Dose | TIMEPOINT:+4HR POST INFUSION |
F11 | Group:Low-Dose | TIMEPOINT:+71HR POST INFUSION |
F12 | Group:Low-Dose | TIMEPOINT:BASELINE |
F13 | Group:Placebo | TIMEPOINT:-0.5HR |
F14 | Group:Placebo | TIMEPOINT:+23HR POST INFUSION |
F15 | Group:Placebo | TIMEPOINT:+47HR POST INFUSION |
F16 | Group:Placebo | TIMEPOINT:+4HR POST INFUSION |
F17 | Group:Placebo | TIMEPOINT:+71HR POST INFUSION |
F18 | Group:Placebo | TIMEPOINT:BASELINE |