Data for (Study ST000164)

(Analysis AN000256)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Metabolite	F1	F2	F3	F4
1-Linoleoylglycerophosphocholine	0.5294	0.7534	1.0561	1.5435
24,25-hydroxyvitamin D3	0.9167	0.8322	0.8755	1.3548
2-Methylbutyroylcarnitine	0.8941	1.1073	1.0208	0.9513
2-Pyrrolidinone	0.6951	0.9476	1.1635	1.1175
3-Hydroxy-L-proline	0.6647	0.8872	1.0436	1.3206
3-Methyl-2-oxovaleric acid	1.0172	0.9179	1.1090	0.9602
4-Aminobutyraldehyde	1.0136	1.0881	0.9460	0.9556
4-Guanidinobutanamide	1.0920	0.9793	0.9445	1.0072
4-Guanidinobutanoic acid	1.0947	0.9603	0.9210	1.0478
4-Hydroxypyridine	0.7697	1.1196	1.1334	0.9198
7-ketocholesterol	0.7409	0.2884	0.8237	2.0822
Acetylcarnitine	0.8284	1.5101	0.5954	1.0232
Acetylcholine	0.6154	1.0996	0.9138	1.2751
Acetyl-L-serine	0.7022	1.2501	0.8588	1.1144
Adenosine	0.7619	0.7441	0.8353	1.5992
ADMA	0.7620	1.0291	1.0563	1.0931
ADP-ribose	0.8812	0.9944	0.8431	1.2516
Agmatine	1.3482	0.6144	1.0922	1.0323
Alanine	0.6945	1.1037	0.9445	1.1810
Allantoate	0.8283	1.0429	0.9269	1.1590
Aminoadipic acid	0.0963	0.7855	1.3544	1.5379
Aminoethylphosphonic acid	0.7187	1.0510	0.9641	1.1958
Aminopropanol	0.8253	0.8819	0.8836	1.3656
AMP	1.1640	0.8094	0.8846	1.1830
Anthranilic acid	0.7605	1.1348	0.9794	1.0654
Arabitol	0.3390	1.3693	0.3200	1.8064
Arachidonic Acid	1.0746	0.9377	0.7479	1.2584
Arachidonoyl Ethanolamide	0.9350	1.0022	0.8445	1.2020
Arginine	0.6147	0.9792	1.1773	1.1326
Asparagine	0.6742	0.9950	0.9755	1.2739
Aspartate	0.5908	1.0530	1.0085	1.2453
Aspartic acid b-semialdehyde	0.9301	0.9251	1.0994	1.0280
Benzoic acid	0.6176	0.8076	1.2586	1.2045
Betaine	0.8209	1.0227	1.0698	1.0418
Betaine aldehyde	0.8373	1.1976	0.9550	0.9695
Biotin	0.9033	1.1125	0.9008	1.0593
Biotin amide	0.7721	1.1652	0.8329	1.1728
Butyric acid	0.9879	1.0300	1.0500	0.9290
Butyryl-L-carnitine	0.4378	1.3492	0.5852	1.4873
C-2 Ceramide	1.0113	1.0727	1.1322	0.7867
Cadaverine	0.7430	1.2659	0.9276	0.9992
Caprylic acid	1.0463	0.6780	1.1320	1.1553
Carnitine	0.5123	0.7781	1.2069	1.3807
Carnosine	0.9036	0.9898	1.0402	1.0424
CDPcholine	0.6454	0.9031	1.0055	1.3574
CDP-ethanolamine	0.8647	0.9371	0.8641	1.3003
Cer(d18:0/13:0)	0.7984	0.7027	0.5709	1.8776
Cer(d18:0/16:0)	0.9940	0.7761	0.6977	1.5055
Cer(d18:0/17:0)	1.4181	0.6307	0.5941	1.4615
Cholecalciferol	0.6352	0.5225	0.9519	1.7991
Cholic acid	0.9582	0.9712	0.9735	1.0867
Choline	0.7379	1.1753	0.9017	1.1195
Citrulline	1.0408	0.7664	1.2029	1.0001
CMP	0.9053	1.7923	0.5036	0.7750
CMP-N-acetylneuraminic acid	0.8016	0.9567	0.8212	1.3709
Coumaric acid	0.9006	1.0176	1.0979	0.9590
Creatine	0.8249	1.0724	0.9029	1.1560
Cyclic CMP	1.3485	1.2909	0.6135	0.8343
Cystathionine	0.7887	0.9153	1.1871	1.0561
Cysteine	0.3934	1.3132	0.8160	1.2524
Cysteineglutathione disulfide	1.0458	0.6045	1.6421	0.7191
Cytidine	0.6518	1.3481	0.8455	1.0676
Cytosine	0.6282	1.2435	0.8389	1.1963
delta-Tocopherol	0.5600	0.6264	0.9625	1.7411
Deoxycytosine	0.7629	0.8634	1.1527	1.1617
Dethiobiotin	0.8928	1.5365	0.7855	0.7584
DG(17:1(9Z)/17:1(9Z)/0:0)	0.9310	1.0960	0.9301	1.0257
DG(17:2(9Z,12Z)/18:0/0:0)	0.9548	1.0050	1.0166	1.0123
Diethanolamine	1.0516	1.1417	0.8885	0.9311
Distearyl phosphatidyl ethanolamine	0.6421	1.1109	0.7618	1.3957
DL-2-Aminoadipic acid	0.9464	1.2814	0.5730	1.1859
Docosanamide	0.9569	1.0036	1.1814	0.8473
Dodecanoylcarnitine	0.5716	0.6780	0.7845	1.8588
Dopamine	0.9938	0.9845	1.0528	0.9673
Elaidic carnitine	0.6676	0.7343	0.7049	1.8101
Ergothioneine	0.5813	1.2177	0.7949	1.3014
Erythritol	0.6204	1.0097	0.9790	1.2960
Formimino-L-glutamic acid	0.7971	1.2465	0.8584	1.0473
Gamma-Butyrolactone	0.8321	1.1609	1.0554	0.9096
Glucosamine 1-phosphate	1.0171	1.1578	0.9080	0.9214
Glucose	0.6712	1.1025	0.9048	1.2393
Glucose 6-phosphate	0.6363	1.2613	0.9754	1.0579
Glutamate	0.6191	1.3453	0.8122	1.1281
Glutamic acid g-semialdehyde	0.7987	0.8301	1.2494	1.0714
Glutamine	0.6146	1.0581	1.0057	1.2253
Glutathione	0.6070	1.1767	0.8497	1.2684
Glutathione, oxidized	0.6357	1.1450	0.8152	1.3131
Glyceraldehyde 3-phosphate	0.5021	1.7269	0.6625	0.9559
Glyceric acid	1.1102	0.9669	1.0199	0.9306
Glycerol	0.9316	1.2935	0.8275	0.9548
Glycerophosphocholine	0.6017	1.3759	0.8403	1.0825
Glycerylphosphorylethanolamine	0.7957	1.1215	0.9299	1.1018
Glycine	0.5854	1.0429	0.9124	1.3556
Glycocholic Acid	0.9946	1.0597	1.0749	0.8698
GMP	0.8492	1.1213	0.7373	1.2545
Guanidineacetic acid	0.8052	0.8745	0.9075	1.3641
Guanine	1.0212	1.0106	0.4646	1.5089
H2O4S	0.8139	1.1252	0.9222	1.0921
Hexanoylcarnitine	1.0659	1.0561	0.8100	1.0844
Histamine	0.7903	1.0355	1.0192	1.1026
Histidinal	0.9419	0.8692	1.1719	1.0025
Histidine	0.5765	1.1734	0.9551	1.1891
Histidinol	0.8716	1.0426	1.0953	0.9584
Homoserine	0.7029	0.9480	1.1535	1.1213
Homovanillic acid	0.7568	1.8143	0.3262	0.9231
Hydrogen selenide	0.7637	1.3230	1.1380	0.7163
Hydroxy butyric acid	0.8208	1.3367	0.8896	0.9081
Hydroxyhydroquinone	0.6431	1.1094	0.9182	1.2400
Hydroxy-L-glutamic acid	0.8618	0.9887	1.0450	1.0700
Hydroxylysine	0.9015	1.0513	1.2982	0.7244
Hypotaurine	0.5476	0.9158	1.1576	1.2660
Hypoxanthine	0.6687	0.8186	1.0933	1.3365
Imidazoleacetic acid	0.7748	1.3078	0.7531	1.1080
IMP	0.8917	0.9519	0.8051	1.3242
Inosine	0.8866	0.8448	1.0070	1.2333
Isobutyryl-L-carnitine	0.9434	1.0438	0.9512	1.0475
Isoleucine	0.6278	1.0867	1.1007	1.0917
Isovaleric acid	0.9240	1.0645	1.0238	0.9687
Ketoleucine	0.9824	1.1885	0.8116	1.0131
Kynuramine	1.4962	0.8190	0.9854	0.8235
Kynurenic acid	0.9468	1.0715	0.8876	1.0808
Lauric acid	0.7295	1.2401	0.8183	1.1331
L-Homocysteic acid	1.6264	0.4551	0.6689	1.4063
Linoleyl carnitine	0.5324	0.7337	0.6073	2.0098
Lysine	0.6082	1.0382	1.0355	1.2202
LysoPE	0.9591	0.8677	0.9472	1.2157
Malonylcarnitine	0.8554	0.8697	1.0714	1.1673
Metformin	1.6653	0.0733	2.3487	0.0791
Methionine	0.5620	1.1223	1.0799	1.1264
Methylcytidine	0.9294	1.4565	0.9737	0.6228
Methylglutarylcarnitine	0.9988	1.0282	1.0885	0.8842
Methylhistamine	0.5294	1.2054	1.0582	1.0893
Methyl-L-histidine	1.1678	0.9500	1.0922	0.8320
Mevalonic acid	0.4936	0.6328	0.9749	1.7720
N1-Acetylspermidine	0.3003	0.7525	1.6721	1.1002
N2-Acetyl-L-ornithine	1.0573	1.1413	0.8352	0.9805
Na-Acetyl-L-glutamine	0.5465	1.1836	0.8291	1.3274
N-acetylaspartate	0.3848	1.7669	0.7673	0.9271
N-Acetylcadaverine	1.2890	0.8548	1.1759	0.7525
N-Acetyl-DL-methionine	1.1137	1.0613	0.9989	0.8595
N-Acetyl-L-alanine	0.7816	0.9655	1.2199	0.9783
N-Acetyl-L-glutamic acid	0.9992	0.9258	0.9298	1.1450
N-Acetylneuraminic Acid	1.0698	1.3668	0.9130	0.6679
N-Acetylputrescine	0.8184	1.2170	1.2693	0.6499
N-Acetylserotonin	0.5589	1.1331	0.9873	1.2104
N-Acryloylglycine	0.5470	1.0583	0.9701	1.3113
NAD	0.8007	0.8542	0.8375	1.4578
N-Carbamoylputrescine	0.6135	1.0835	1.0941	1.1123
Ne-Methyl-L-lysine	0.6005	1.0639	0.9414	1.2944
Niacinamide	0.6878	1.0063	0.9944	1.2335
N-Methylurea	1.0019	0.9849	1.1364	0.8772
N,N^-Dimethylurea	1.2574	1.0894	0.8777	0.8399
N-Palmitoylsphingosine	0.9311	0.7115	0.5761	1.7640
Octanoylcarnitine	1.2246	1.0491	1.0278	0.7546
O-Phosphorylethanolamine	0.7573	0.8822	0.9588	1.3410
Ornithine	0.5062	1.1806	0.6008	1.5890
Palmitoyl-L-carnitine	0.4724	0.7684	0.8595	1.7678
Pantoic acid	0.8898	0.9720	1.1040	1.0066
Pantothenic Acid	1.0738	0.9675	0.9633	1.0138
PC(10:0/11:0)[U]	1.0183	0.6002	0.8879	1.4982
PC(10:0/13:0)[U]	1.0114	0.5908	0.9805	1.3861
PC(16:0/0:0)	0.4938	0.7603	1.0881	1.5312
PC(16:0/5:1(4E))	0.9955	0.9346	0.9769	1.0919
PC(18:1(9Z)/0:0)[U] / PC(18:1(9Z)/0:0)[rac]	0.6240	0.7912	1.1268	1.3640
PC(20:4(5Z,8Z,11Z,14Z)/0:0)	0.5478	0.7983	1.1284	1.4125
PC(24:0/0:0)	0.7012	0.4537	0.9650	1.7264
Phenylalanine	0.5501	1.0568	1.0970	1.1836
Phosphocholine	0.6426	1.1490	0.9492	1.1698
Phospho-L-serine	0.9606	1.0246	1.0166	0.9900
Phosphoric acid	0.8212	1.1205	0.9375	1.0761
Phosphorylcholine	1.0167	0.9885	0.9026	1.0964
progesterone	0.9930	1.0380	0.9869	0.9803
Proline	0.6926	1.1504	0.8780	1.2021
Propionyl-L-carnitine	0.5007	1.0581	0.9984	1.3180
PS(19:0/0:0)	1.2088	0.7483	1.2409	0.8310
PS(22:1(11Z)/0:0)	0.9901	0.5513	0.8304	1.6257
Psychosine	1.2453	0.8226	1.0960	0.8881
Putrescine	0.4174	1.4046	1.0120	1.0204
Pyridoxal (Vitamin B6)	0.8948	1.0735	0.9890	1.0164
Pyridoxamine	1.0131	0.9050	1.0296	1.0556
Pyridoxate	0.7940	1.7231	0.6387	0.8538
Pyrrolidone-5-carboxylic acid	0.5479	1.4271	0.7536	1.1583
Quinic acid	0.9495	0.9223	1.0101	1.1056
Retinoic acid	1.0369	0.9881	0.9763	1.0079
Ribitol	1.2083	0.8065	0.9327	1.1046
Ribose 5-phosphate	0.8840	1.4185	0.6620	1.0576
Sarcosine	0.9085	0.9519	1.0992	1.0175
Selenium Sulfide	0.8579	0.8632	1.0119	1.2314
Selenocysteine	0.9461	1.1290	0.8418	1.0696
Serine	0.5689	1.0240	1.0978	1.2016
Serotonin	1.0615	1.0311	0.9803	0.9425
Skatole	0.9921	1.0456	1.1419	0.8185
Spermine	1.2217	1.4962	0.8427	0.4949
Sphinganine	0.9139	0.8651	1.0662	1.1333
Stearoylcarnitine	0.2847	0.5997	0.8401	2.0966
Succinate	0.6835	1.5535	0.8602	0.8237
Succinic acid semialdehyde	0.9267	1.2511	0.9573	0.8466
Sucrose	0.5295	1.5320	0.6197	0.9592
Sulfite	1.0449	1.2799	0.9037	0.7827
Taurine	0.6898	1.0197	0.9878	1.2252
Testosterone	1.0408	0.9691	0.9009	1.0994
Thiamine	0.5088	0.9377	1.3157	1.0741
Threonine	0.6416	1.0876	0.9753	1.2059
Thymine	0.9197	1.0375	1.0799	0.9428
Trigonellinamide	0.5260	0.9567	0.9260	1.4728
Trigonelline	1.1819	0.8613	0.8596	1.1426
Tryptophan	0.6117	1.1949	1.0844	1.0119
Tryptophol	0.9842	0.9278	0.9399	1.1442
Tyramine	0.7056	0.9952	1.3129	0.9128
Tyrosine	0.5940	1.1892	1.0019	1.1134
UDP	0.7929	1.0192	0.7716	1.3646
UDP-D-galactose	0.8773	0.9725	0.8410	1.2785
UDP-N-acetyl-D-galactosamine	0.7767	1.0042	0.7961	1.3672
UMP	0.7639	1.1237	0.9298	1.1339
Uric acid	1.0170	0.8892	1.1252	0.9729
Urocanic acid	0.6985	1.4505	1.0090	0.7666
Valine	0.7278	1.0981	0.9770	1.1290
Xylitol	0.9545	1.0453	0.9792	1.0096

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1	Mice health condition:MKR | Treatment:Metformin
F2	Mice health condition:MKR | Treatment:PBS buffer
F3	Mice health condition:wild type | Treatment:Metformin
F4	Mice health condition:wild type | Treatment:PBS buffer