Data for (Study ST002123)
(Analysis AN003476)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 |
|---|---|---|
| 1-Methyladenosine | 1.2332 | 0.7668 |
| 1-Methyl-Histidine | 0.6732 | 1.3268 |
| 1-methylnicotinamide | 1.1993 | 0.8007 |
| 2,3-dihydroxybenzoic acid | 0.7559 | 1.2441 |
| 2,3-Diphosphoglyceric acid | 0.6099 | 1.3901 |
| 2-Aminooctanoic acid | 1.0726 | 0.9274 |
| 2-dehydro-D-gluconate | 1.0914 | 0.9086 |
| 2-deoxyglucose-6-phosphate | 1.5412 | 0.4588 |
| 2-Hydroxy-2-methylbutanedioic acid | 1.8182 | 0.1818 |
| 2-Isopropylmalic acid | 1.5445 | 0.4555 |
| 2-Ketohexanoic acid | 0.5979 | 1.4021 |
| 2-oxo-4-methylthiobutanoate | 1.1229 | 0.8771 |
| 2-oxobutanoate | 1.6830 | 0.3170 |
| 3-hydroxy-3-methylglutaryl-CoA | 0.7413 | 1.2587 |
| 3-hydroxybutyryl-CoA | 1.0176 | 0.9824 |
| 3-methylphenylacetic acid | 0.7529 | 1.2471 |
| 3-Methylthiopropionate | 0.7941 | 1.2059 |
| 3-phosphoglycerate | 1.0039 | 0.9961 |
| 3-phospho-serine | 0.7746 | 1.2254 |
| 4-aminobutyrate | 0.9893 | 1.0107 |
| 4-Pyridoxic acid | 0.4300 | 1.5700 |
| 5-methoxytryptophan | 1.5036 | 0.4964 |
| 5-Methyl-tetrahydrofolate | 0.7785 | 1.2215 |
| 5^-Methylthioadenosine | 1.0631 | 0.9369 |
| 5-phosphoribosyl-1-pyrophosphate | 0.6484 | 1.3516 |
| 6-phospho-D-gluconate | 0.8124 | 1.1876 |
| 6-phospho-D-glucono-1,5-lactone | 0.7129 | 1.2871 |
| 7,8-dihydrofolate | 0.6723 | 1.3277 |
| 7-methylguanosine | 1.2031 | 0.7969 |
| acadesine | 0.8463 | 1.1537 |
| acetoacetate | 1.7100 | 0.2900 |
| acetoacetyl-CoA | 0.5446 | 1.4554 |
| acetyl-CoA | 1.6647 | 0.3353 |
| Acetyllysine | 1.2436 | 0.7564 |
| acetylphosphate | 0.8892 | 1.1108 |
| aconitate | 1.5377 | 0.4623 |
| adenine | 0.4172 | 1.5828 |
| adenosine | 0.9626 | 1.0374 |
| Adenosine phosphosulfate | 0.4143 | 1.5857 |
| ADP | 1.4272 | 0.5728 |
| ADP-D-glucose | 1.7361 | 0.2639 |
| a-ketoglutarate | 1.4700 | 0.5300 |
| alanine | 1.1572 | 0.8428 |
| allantoate | 0.7273 | 1.2727 |
| allantoin | 0.6328 | 1.3672 |
| Alpha-ketoisovaleric acid | 0.8919 | 1.1081 |
| Aminoadipic acid | 0.4356 | 1.5644 |
| aminoimidazole carboxamide riboNucleotides | 0.4985 | 1.5015 |
| AMP | 1.2847 | 0.7153 |
| anthranilate | 1.3386 | 0.6614 |
| arginine | 1.3245 | 0.6755 |
| Ascorbic acid | 0.6569 | 1.3431 |
| asparagine | 1.1854 | 0.8146 |
| aspartate | 1.2151 | 0.7849 |
| ATP | 1.3165 | 0.6835 |
| Atrolactic acid | 0.6727 | 1.3273 |
| betaine | 0.8780 | 1.1220 |
| betaine aldehyde | 1.1365 | 0.8635 |
| Beta-N-Acetylglucosamine | 1.6811 | 0.3189 |
| biotin | 0.5618 | 1.4382 |
| butyryl-CoA | 0.7413 | 1.2587 |
| Carbamoyl phosphate | 1.2166 | 0.7834 |
| carnitine | 1.0286 | 0.9714 |
| CDP | 0.4582 | 1.5418 |
| CDP-choline | 1.3956 | 0.6044 |
| CDP-ethanolamine | 1.3471 | 0.6529 |
| Cellobiose | 0.5237 | 1.4763 |
| Cholesterol sulfate | 1.0203 | 0.9797 |
| Cholic acid | 0.4883 | 1.5117 |
| choline | 0.8256 | 1.1744 |
| Citraconic acid | 1.6062 | 0.3938 |
| citrate | 1.4612 | 0.5388 |
| Citric acid | 0.5249 | 1.4751 |
| citrulline | 0.6378 | 1.3622 |
| CMP | 1.2796 | 0.7204 |
| coenzyme A | 0.9952 | 1.0048 |
| creatine | 0.9958 | 1.0042 |
| creatinine | 0.4682 | 1.5318 |
| CTP | 1.2763 | 0.7237 |
| Cyclic AMP | 0.5542 | 1.4458 |
| cyclic bis(3->5) dimeric GMP | 0.7413 | 1.2587 |
| cystathionine | 0.5817 | 1.4183 |
| cysteine | 1.0695 | 0.9305 |
| Cystine | 1.1185 | 0.8815 |
| cytidine | 1.3235 | 0.6765 |
| cytosine | 0.6626 | 1.3374 |
| dAMP | 1.3417 | 0.6583 |
| dATP | 0.6177 | 1.3823 |
| dCDP | 0.9578 | 1.0422 |
| dCMP | 1.1628 | 0.8372 |
| dCTP | 1.0328 | 0.9672 |
| deoxyadenosine | 1.1355 | 0.8645 |
| Deoxycholic acid | 0.6225 | 1.3775 |
| deoxyguanosine | 0.9683 | 1.0317 |
| deoxyinosine | 1.0016 | 0.9984 |
| Deoxyribose 5-phosphate | 0.6394 | 1.3606 |
| deoxyuridine | 0.7042 | 1.2958 |
| dephospho-CoA | 1.4144 | 0.5856 |
| D-erythrose-4-phosphate | 1.2987 | 0.7013 |
| dGDP | 0.9160 | 1.0840 |
| D-glucarate | 0.6402 | 1.3598 |
| D-gluconate | 1.5876 | 0.4124 |
| D-glucosamine-1-phosphate | 1.4429 | 0.5571 |
| D-glucosamine-6-phosphate | 1.5942 | 0.4058 |
| D-Glyceraldehyde 3-phosphate | 1.4480 | 0.5520 |
| dGMP | 0.9177 | 1.0823 |
| dGTP | 1.2148 | 0.7852 |
| dihydroorotate | 0.9091 | 1.0909 |
| dihydroxy-acetone-phosphate | 1.5108 | 0.4892 |
| Diiodothyronine | 0.9682 | 1.0318 |
| dimethylglycine | 1.0444 | 0.9556 |
| DL-Pipecolic acid | 1.2951 | 0.7049 |
| D-sedoheptulose-1-7-phosphate | 1.5341 | 0.4659 |
| dTDP | 0.8838 | 1.1162 |
| dTMP | 0.7828 | 1.2172 |
| dTTP | 0.9002 | 1.0998 |
| dUMP | 0.7318 | 1.2682 |
| dUTP | 0.4046 | 1.5954 |
| ethanolamine | 1.0953 | 0.9047 |
| FAD | 1.4199 | 0.5801 |
| Farnesyl pyrophosphate | 0.6471 | 1.3529 |
| Flavone | 0.7187 | 1.2813 |
| FMN | 0.8946 | 1.1054 |
| folate | 1.1300 | 0.8700 |
| Fructose 1,6-bisphosphate | 1.2157 | 0.7843 |
| fructose-6-phosphate | 1.3258 | 0.6742 |
| fumarate | 1.5845 | 0.4155 |
| GDP | 0.6814 | 1.3186 |
| Geranyl-PP | 0.8677 | 1.1323 |
| glucono-D-lactone | 0.9527 | 1.0473 |
| glucosamine | 1.6133 | 0.3867 |
| glucose-1-phosphate | 1.5969 | 0.4031 |
| glucose-6-phosphate | 1.5924 | 0.4076 |
| glutamate | 0.8595 | 1.1405 |
| glutamine | 0.9923 | 1.0077 |
| glutathione | 1.6608 | 0.3392 |
| glutathione disulfide | 1.5296 | 0.4704 |
| glutathione disulfide-1 | 0.6254 | 1.3746 |
| glycerate | 1.2252 | 0.7748 |
| Glyceric acid 1,3-biphosphate | 1.3866 | 0.6134 |
| Glycerophosphocholine | 1.0543 | 0.9457 |
| glycine | 1.3616 | 0.6384 |
| glycolate | 1.6801 | 0.3199 |
| glyoxylate | 1.5968 | 0.4032 |
| GMP | 1.6630 | 0.3370 |
| GTP | 0.8237 | 1.1763 |
| Guanidoacetic acid | 0.6225 | 1.3775 |
| guanine | 0.8003 | 1.1997 |
| guanosine | 0.5152 | 1.4848 |
| Guanosine diphosphate | 0.7697 | 1.2303 |
| hexose-phosphate | 1.8676 | 0.1324 |
| histidine | 1.0943 | 0.9057 |
| histidinol | 0.9040 | 1.0960 |
| homocysteic acid | 0.7681 | 1.2319 |
| homocysteine | 1.5405 | 0.4595 |
| homoserine | 1.0728 | 0.9272 |
| Hydroxyisocaproic acid | 1.5902 | 0.4098 |
| Hydroxyphenylacetic acid | 0.8361 | 1.1639 |
| hydroxyphenylpyruvate | 0.7231 | 1.2769 |
| hydroxyproline | 0.8156 | 1.1844 |
| hypoxanthine | 1.3255 | 0.6745 |
| IDP | 0.8993 | 1.1007 |
| Imidazole | 0.7509 | 1.2491 |
| Imidazoleacetic acid | 0.6654 | 1.3346 |
| IMP | 1.5544 | 0.4456 |
| indole | 0.8320 | 1.1680 |
| Indole-3-carboxylic acid | 0.8394 | 1.1606 |
| Indoleacrylic acid | 0.7481 | 1.2519 |
| inosine | 1.3892 | 0.6108 |
| isocitrate | 1.3479 | 0.6521 |
| Kynurenic acid | 0.9823 | 1.0177 |
| Kynurenine | 0.8195 | 1.1805 |
| L-2-Hydroxyglutaric acid | 1.3783 | 0.6217 |
| L-Acetylcarnitine | 0.7404 | 1.2596 |
| lactate | 0.5594 | 1.4406 |
| L-arginino-succinate | 0.4638 | 1.5362 |
| leucine-isoleucine | 0.7914 | 1.2086 |
| lipoate | 0.8009 | 1.1991 |
| lysine | 0.8417 | 1.1583 |
| malate | 1.4850 | 0.5150 |
| Maleic acid | 0.6014 | 1.3986 |
| malonyl-CoA | 0.4984 | 1.5016 |
| methionine | 0.9073 | 1.0927 |
| Methionine sulfoxide | 1.4789 | 0.5211 |
| Methylcysteine | 1.1203 | 0.8797 |
| Methylmalonic acid | 0.9081 | 1.0919 |
| myo-inositol | 0.8621 | 1.1379 |
| N6-Acetyl-L-lysine | 0.9440 | 1.0560 |
| N-acetyl-glucosamine-1-phosphate | 1.7409 | 0.2591 |
| N-acetyl-glutamate | 1.2779 | 0.7221 |
| N-acetyl-glutamine | 1.2873 | 0.7127 |
| N-Acetyl-L-alanine | 1.2014 | 0.7986 |
| N-Acetylornithine | 1.5119 | 0.4881 |
| N-Acetylputrescine | 1.0166 | 0.9834 |
| NAD+ | 1.0316 | 0.9684 |
| NADH | 0.9015 | 1.0985 |
| NADP+ | 0.8203 | 1.1797 |
| NADPH | 0.7002 | 1.2998 |
| N-carbamoyl-L-aspartate | 1.4176 | 0.5824 |
| Ng,NG-dimethyl-L-arginine | 1.2761 | 0.7239 |
| nicotinamide | 1.1510 | 0.8490 |
| Nicotinamide ribotide | 0.6456 | 1.3544 |
| nicotinate | 0.3556 | 1.6444 |
| O-acetyl-L-serine | 0.6161 | 1.3839 |
| octulose-1,8-bisphosphate (OBP) | 1.7372 | 0.2628 |
| octulose-monophosphate (O8P-O1P) | 1.6026 | 0.3974 |
| OMP | 0.7788 | 1.2212 |
| ornithine | 0.5608 | 1.4392 |
| orotate | 0.6161 | 1.3839 |
| oxaloacetate | 1.3700 | 0.6300 |
| p-aminobenzoate | 0.8023 | 1.1977 |
| pantothenate | 1.0398 | 0.9602 |
| phenylalanine | 0.9755 | 1.0245 |
| Phenyllactic acid | 1.1436 | 0.8564 |
| Phenylpropiolic acid | 0.4631 | 1.5369 |
| phenylpyruvate | 1.3578 | 0.6422 |
| phosphoenolpyruvate | 1.2288 | 0.7712 |
| Phosphorylcholine | 1.0414 | 0.9586 |
| p-hydroxybenzoate | 0.8596 | 1.1404 |
| prephenate | 0.5109 | 1.4891 |
| proline | 1.0570 | 0.9430 |
| propionyl-CoA | 1.4763 | 0.5237 |
| purine | 1.0491 | 0.9509 |
| Pyridoxamine | 0.5021 | 1.4979 |
| pyridoxine | 0.5252 | 1.4748 |
| Pyroglutamic acid | 0.7783 | 1.2217 |
| Pyrophosphate | 0.7249 | 1.2751 |
| pyruvate | 1.3111 | 0.6889 |
| quinolinate | 0.7440 | 1.2560 |
| riboflavin | 0.6153 | 1.3847 |
| ribose-phosphate | 1.8515 | 0.1485 |
| S-adenosyl-L-homoCysteine | 1.2594 | 0.7406 |
| S-adenosyl-L-methionine | 0.6402 | 1.3598 |
| S-Adenosylmethioninamine | 0.7964 | 1.2036 |
| sarcosine | 0.8250 | 1.1750 |
| Sedoheptulose 1,7-bisphosphate (SBP) | 1.7874 | 0.2126 |
| serine | 0.1577 | 1.8423 |
| shikimate | 1.7564 | 0.2436 |
| Shikimate 3-phosphate | 0.9009 | 1.0991 |
| sn-glycerol-3-phosphate | 1.3755 | 0.6245 |
| spermidine | 0.6717 | 1.3283 |
| spermine | 0.5015 | 1.4985 |
| S-ribosyl-L-homocysteine | 0.6717 | 1.3283 |
| succinate | 1.1450 | 0.8550 |
| succinyl-CoA | 1.3858 | 0.6142 |
| succinyl-CoA-methylmalonyl-CoA | 0.9982 | 1.0018 |
| sucrose | 0.7360 | 1.2640 |
| taurine | 0.9422 | 1.0578 |
| Taurodeoxycholic acid | 0.9904 | 1.0096 |
| thiamine | 1.3289 | 0.6711 |
| Thiamine monophosphate | 1.3763 | 0.6237 |
| Thiamine pyrophosphate | 1.2370 | 0.7630 |
| threonine | 1.2269 | 0.7731 |
| thymidine | 0.6600 | 1.3400 |
| thymine | 1.1247 | 0.8753 |
| trehalose-6-Phosphate | 1.5251 | 0.4749 |
| tryptophan | 0.9385 | 1.0615 |
| tyrosine | 0.8033 | 1.1967 |
| UDP | 1.0621 | 0.9379 |
| UDP-D-glucose | 1.3324 | 0.6676 |
| UDP-D-glucuronate | 1.5889 | 0.4111 |
| UDP-N-acetyl-glucosamine | 1.4268 | 0.5732 |
| UMP | 1.3013 | 0.6987 |
| uracil | 0.7586 | 1.2414 |
| Urea | 0.6319 | 1.3681 |
| Uric acid | 1.6523 | 0.3477 |
| uridine | 1.1651 | 0.8349 |
| UTP | 0.2660 | 1.7340 |
| valine | 1.4227 | 0.5773 |
| xanthine | 1.3645 | 0.6355 |
| xanthosine | 1.6284 | 0.3716 |
| Xanthurenic acid | 0.8802 | 1.1198 |
| Xanthylic acid | 0.5217 | 1.4783 |
Factors:
| F1 | Genotype:Mutant | Treatment:5 FU 2 weeks | Batch:1f | Source_Name[gating]:Lin– Scal1+ c-Kit+ (LSK) |
| F2 | Genotype:Wild-type | Treatment:5 FU 2 weeks | Batch:1f | Source_Name[gating]:Lin– Scal1+ c-Kit+ (LSK) |
