Data for (Study ST003204)

(Analysis AN005255)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8
1-Aminocyclopropanecarboxylic acid 0.8338 1.3047 1.1826 1.0938 0.3144 1.2233 0.8302 0.7115
1-Methyladenosine 0.4426 0.2758 1.2367 1.1674 0.1557 1.3765 0.5234 2.8218
1-Methyl nicotinamide 0.1805 0.1934 0.4043 0.7080 0.9455 1.2044 1.8545 2.5093
2-Amino-2-deoxy-D-mannose 0.2219 0.1530 1.1015 1.5662 0.5011 0.5968 1.3578 2.5018
3-Aminoisobutanoic acid 0.6199 0.5924 0.9454 1.0396 1.2006 1.3468 0.8274 1.4279
3-Dehydroxycarnitine 0.1167 0.1090 0.4979 0.7217 1.7373 2.0558 0.9746 1.7871
3-Methoxytyramine 1.0587 0.9195 1.6973 0.5744 0.8078 1.9418 0.4606 0.5399
3-Methyladenine 0.7523 0.7965 1.0625 1.0782 1.2485 0.7695 1.0088 1.2837
3-Methylhistamine 1.1374 0.3642 1.0137 0.7211 1.1374 1.4507 0.7462 1.4294
3-Methylhistidine 0.7605 0.7065 1.6169 0.6193 1.0795 1.8822 0.6449 0.6901
4a-Carbinolamine tetrahydrobiopterin 0.8747 1.5251 0.7646 1.0418 0.6991 0.5838 1.1135 1.1017
4-Acetamidobutanoic acid 0.9458 0.6335 1.1667 0.5572 0.9212 2.2199 1.0148 0.5409
4-Guanidinobutanoic acid 0.5268 0.2708 0.3461 0.2974 1.2814 1.7905 1.5613 1.9258
5-Amino-levulinic acid NA 0.1296 0.2608 0.1237 0.3603 5.4038 0.1719 0.3034
5-Hydroxy-tryptophan 1.5974 0.9801 2.3052 0.3979 0.8377 0.2123 1.4008 0.2685
5-Methylcytosine 1.2064 0.7924 1.3972 1.0265 0.7419 0.7732 1.0586 1.0038
5^-Methylthioadenosine 2.3083 1.8950 1.6222 0.2732 0.3666 0.5974 0.2230 0.7142
6-Hydroxydopamine 1.1394 0.7078 1.6445 0.5772 0.9697 0.8677 1.3343 0.7594
Acetylcholine 0.1211 0.1133 0.5495 0.8218 1.4305 2.3612 0.8324 2.2239
Adenine 1.1011 0.6327 0.8935 0.5764 1.0198 1.3780 0.7345 1.6640
Alanine 0.4376 0.3195 0.8872 1.0392 2.2342 2.4815 0.2280 0.3729
Alanine_13C1 1.2241 0.8842 0.9492 0.7976 1.3718 1.4855 0.7839 0.5036
Allothreonine 1.2195 1.2347 1.0364 0.4500 1.0222 2.0949 0.4765 0.4657
alpha-Aminoadipic acid 1.4941 0.9699 1.2366 0.8353 0.9359 1.5644 0.3154 0.6484
Aminoisobutyric acid 0.7385 0.6370 1.1027 0.9188 1.3012 0.8251 0.9324 1.5444
Anserine 0.2002 0.2835 0.9185 NA 1.1037 1.5780 1.3314 0.5195
Arginine 1.2054 0.8858 1.5996 0.8816 0.8664 0.9061 1.0780 0.5772
Asparagine 0.1712 0.6773 0.3331 1.3356 0.1200 1.8833 0.2596 3.2199
Asparagine_15N1 0.9586 1.1003 0.9734 0.6462 0.9948 2.1238 0.6014 0.6016
Asparagine_15N2 0.1535 0.3489 1.1869 0.9642 0.2355 3.9771 0.2639 0.3329
beta-Alanine 0.2353 0.1085 0.5897 1.2931 1.5873 1.9350 0.5486 1.7025
Betaine 0.7270 0.5022 0.9721 0.6831 1.5081 2.1233 0.7061 0.7781
CAR 2:0 0.0751 0.1530 1.5108 1.6197 0.3568 2.6946 0.3727 1.2173
Carnitine 0.1641 0.1094 0.7024 1.2684 1.1377 1.6061 1.5095 1.5025
Carnosine 1.1245 0.7202 1.4549 0.4477 1.4742 0.9721 1.1322 0.6743
Choline NA NA NA 0.2397 0.9525 1.0525 1.8078 0.9633
Choline phosphate 0.8197 0.8104 0.8507 0.9866 1.1532 1.3170 0.8779 1.1845
cis-4-Hydroxy-D-proline 1.9063 1.6767 0.9947 0.0357 NA 0.0196 0.7063 0.6911
Citrulline 1.1193 0.9011 1.2506 0.5101 0.9800 1.6445 0.7025 0.8919
Creatine 0.3290 0.2016 0.9493 1.2348 2.5204 2.4768 0.1565 0.1316
Creatinine 1.0545 0.6981 1.3772 0.6559 1.0404 1.0238 1.2523 0.8978
Cystathionine 1.7085 1.8942 1.4964 1.2575 0.3230 0.7945 0.0960 0.4299
Cystine 1.3376 0.7920 2.3331 0.4241 0.8674 0.7603 1.2240 0.2615
Cytidine 0.0991 0.0758 2.2419 1.2769 0.6580 0.4953 1.3666 1.7864
Cytosine 1.5200 1.1477 1.4378 0.8303 0.2841 0.5157 1.0329 1.2315
D-Alanine 0.4355 0.3196 0.8881 1.0395 2.2350 2.4824 0.2281 0.3718
D-Alanine_13C1 0.6717 0.8798 1.2682 0.9448 1.0748 1.2018 0.7524 1.2065
D-Alanine_13C2 0.9237 0.8091 1.4471 1.0378 1.2010 1.1388 0.8799 0.5626
D-Alanine_15N1 0.3131 0.7399 0.7116 0.6427 0.7206 2.6017 0.8973 1.3732
Dethiobiotin 0.3435 0.1600 0.6461 0.5621 1.5065 2.5434 0.6469 1.3116
Diethanolamine 0.7507 0.6489 0.5614 0.6740 1.0428 1.1171 0.8032 2.4019
Dihydrouracil 0.3878 0.4632 0.5751 1.1166 2.3574 2.2206 0.2935 0.4069
Dimethylarginine 0.9998 0.6362 1.3615 0.7357 1.0854 1.5770 0.9194 0.6850
D-Ornithine 1.5145 1.0341 1.6779 0.7074 0.8685 0.5227 1.0943 0.5807
Ethyl 3-indoleacetate 1.3664 0.6723 1.0922 0.9751 1.1752 0.7548 0.9678 0.9878
Galactosamine 1.7316 1.7581 2.2195 0.5670 0.3734 0.0737 1.1953 0.0815
Glucosamine 0.2219 0.1530 1.1015 1.5662 0.5011 0.5968 1.3578 2.5018
Glucosaminic acid 0.9665 2.6281 0.3709 0.0578 0.2005 3.5959 0.0362 0.1442
Glutamine_13C1 1.4247 0.9696 1.2315 0.6749 0.7426 1.5315 0.6588 0.7664
Glutamine_13C2 1.7745 0.5139 0.9202 1.8877 0.7122 0.8561 0.5277 1.2153
Glutamine_13C3 0.7841 0.7899 0.9014 1.0073 1.0208 1.1556 1.1003 1.2406
Glutamine_13C4 0.9271 0.8580 0.9857 0.9976 1.1403 1.1595 1.1084 0.8234
Glutamine_13C5 0.7024 0.7236 0.4873 NA 1.3667 1.3781 NA NA
Glutamine_15N1 1.0653 0.9388 0.7443 0.2997 1.2630 2.8965 0.3826 0.4099
Glutamine_15N2 1.1155 0.8402 0.8497 0.6501 0.9714 2.1922 0.6584 0.7226
Glutathione 0.2739 0.3549 0.3949 1.2647 0.6259 2.3620 0.3416 2.3821
Glyoxylic acid 1.2637 0.6804 1.1194 0.8706 0.7364 0.6451 1.6004 1.0840
Guanidinosuccinic acid 1.2699 1.3830 0.9044 0.7071 0.9868 1.3481 0.7354 0.6654
Gulose 1.4030 0.8271 1.6258 0.9688 0.9212 0.6618 1.0163 0.5815
Histamine 1.6437 0.8103 1.8796 0.8002 0.7079 0.7524 1.0285 0.3774
Histidine 1.2384 0.9535 1.3552 0.5340 0.8838 1.5494 0.8290 0.6567
Homogentisic acid 3.3472 1.3133 1.9000 0.2259 0.2779 0.2997 0.4556 0.2223
Homoserine 1.2198 1.2348 1.0366 0.4500 1.0223 2.0950 0.4757 0.4657
Hypotaurine 0.3253 0.1113 0.7095 1.0420 1.5781 1.3968 0.9100 1.9269
Hypoxanthine 0.2108 0.0452 2.8487 2.0979 0.0652 0.2125 2.0701 0.4496
Inosine 0.0920 NA 0.4362 0.6293 0.2032 0.5199 2.2998 2.3771
Isoleucine 1.1450 0.8098 1.5010 0.6104 0.9874 1.5118 0.8467 0.5878
Isoleucine_13C1 1.1082 0.7833 1.4998 0.6131 1.0033 1.5373 0.8648 0.5900
Isoleucine_13C2 1.2088 0.7251 1.8476 0.4548 0.8797 1.5425 0.8097 0.5317
Isoleucine_15N1 0.3675 0.7555 0.3716 0.3979 0.8071 2.8070 0.4537 2.0397
Kynurenine 1.1523 0.8946 1.4210 0.4004 0.9914 1.9277 0.6586 0.5540
Leucine 1.1226 0.8086 1.4407 0.6428 1.0060 1.5474 0.8310 0.6009
Leucine_15N1 0.4275 0.4417 0.3915 0.2712 0.4530 3.1830 0.3284 2.5036
Lipoamide 0.6753 0.6809 1.2259 1.4049 1.2534 0.4605 0.9159 1.0236
Lumichrome 1.5118 0.9093 1.9457 1.1020 0.5376 0.4781 0.9472 0.5682
Lysine 1.2430 0.8155 1.7881 0.7591 0.8822 0.9027 1.1108 0.4987
Methionine 1.0886 0.8508 1.3244 0.6037 1.0035 1.7201 0.7404 0.6684
N(2)-Acetyllysine 0.9058 0.7793 0.9634 1.1056 0.7968 1.8785 0.8692 0.7014
N6-Isopentenyladenine 0.6915 0.6679 0.9034 0.5826 0.9360 3.0910 0.3955 0.3914
N-6-Trimethyllysine 0.9333 0.6544 1.2727 0.6935 1.3076 1.8772 0.7250 0.5363
N-Acetyl-D-galactosamine 0.2052 0.1128 0.7122 0.9438 1.0996 1.0361 1.8840 1.7414
N-Acetyl-D-glucosamine 0.2428 0.1162 0.7337 0.9723 1.1328 1.0673 1.9409 1.7940
N-Acetyl-mannosamine 0.2428 0.1162 0.7337 0.9723 1.1329 1.0673 1.9409 1.7940
N-Acetylneuraminic acid 0.6801 0.6708 0.5898 0.3035 1.1838 1.3321 1.8931 1.3468
N-Acetylserotonin 1.3573 1.3181 0.8265 0.4803 1.1168 0.9224 0.8656 1.1131
NAD+ 0.5266 0.4866 0.6354 0.8333 1.2320 1.4058 1.5184 1.6699
NADP+ 0.1953 0.4208 1.8257 2.9592 0.4033 0.1674 0.8063 0.7514
NADPH 0.6285 0.5717 1.4676 1.4106 0.3294 0.8966 0.6434 1.6753
N-Formylglycine 0.6564 0.6299 0.9310 1.0295 1.0263 2.3626 0.4913 0.8730
Niacinamide 1.3704 0.8443 1.9112 0.6836 0.8305 0.5476 1.2600 0.5524
N-METHYL-ALANINE 0.8936 0.8183 1.1296 0.7325 1.0774 1.1391 0.9521 1.2574
Norleucine 1.1226 0.8089 1.4410 0.6428 1.0062 1.5475 0.8309 0.6002
Norvaline 1.1381 1.0510 1.4094 0.6885 0.9053 1.3978 0.8547 0.5552
Octopamine 1.0784 1.0860 1.0627 0.7255 1.0834 1.6702 0.6328 0.6612
Ornithine 1.5136 1.0335 1.6974 0.6976 0.8940 0.5200 1.0937 0.5502
Oxidized glutathione 0.5761 0.2522 1.0804 1.9252 0.4644 1.2295 0.7088 1.7634
Pantothenic acid 1.1059 1.2890 1.1112 1.5569 0.5148 1.2947 0.3475 0.7800
Phenylalanine 1.0308 0.7675 1.2738 0.5807 1.0317 1.8224 0.7548 0.7384
Proline 0.4200 0.2463 0.6480 0.5678 1.3056 1.9274 0.9439 1.9410
Pyridoxamine 0.8490 0.3872 1.1409 1.1215 0.9806 1.5037 0.8782 1.1389
Pyridoxine 1.1394 0.7078 1.6445 0.5772 0.9697 0.8677 1.3343 0.7594
Quinaldic acid 0.4326 0.3827 0.6411 0.4453 1.2369 1.8097 1.4532 1.5986
S-Adenosylhomocysteine 0.2165 0.1815 0.3007 0.3309 0.7831 1.6652 1.4908 3.0313
Sarcosine 0.4371 0.3185 0.8881 1.0398 2.2343 2.4816 0.2289 0.3717
S-Carboxymethyl-cysteine 0.9747 0.9515 1.3446 NA 0.6475 1.0352 0.9152 0.6502
Serine 1.5783 1.1233 1.3274 0.5234 1.1744 1.1928 0.5015 0.5790
Taurine 0.4370 0.1612 0.7832 0.9674 1.7203 1.4436 0.9386 1.5487
Threitol 0.4611 0.3099 1.1438 1.1528 0.5847 0.9311 1.0010 2.4156
Thymine 1.5007 0.8548 2.0197 0.2085 0.4774 0.3882 1.6038 0.4194
Trigonelline 0.3880 0.3175 0.6764 0.8604 1.1136 1.3335 1.3981 1.9125
Tryptophan 0.9795 0.7457 1.2829 0.5774 1.0584 1.8040 0.7839 0.7683
Tyrosine 1.0835 0.8698 1.3435 0.6491 1.0612 1.5566 0.7774 0.6590
UDP-N-acetylgalactosamine 0.4157 0.2517 1.2991 1.0163 NA 0.3391 3.1867 NA
Valine 1.2251 1.0467 1.3264 0.6521 0.9089 1.4052 0.8804 0.5553
XMP 0.3729 2.1294 0.3364 0.3343 0.4000 0.1581 2.4612 1.5270
Xylose 0.9548 0.9220 1.1340 0.6907 1.0952 1.6725 0.7736 0.7572
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Factors:

F1Sample source:Human Renal 769P Cells | Treatment:RquA 0.5% O2
F2Sample source:Human Renal 769P Cells | Treatment:RquA 21% O2
F3Sample source:Human Renal 769P Cells | Treatment:WT 0.5% O2
F4Sample source:Human Renal 769P Cells | Treatment:WT 21% O2
F5Sample source:Human Renal Caki1 Cells | Treatment:RquA 0.5% O2
F6Sample source:Human Renal Caki1 Cells | Treatment:RquA 21% O2
F7Sample source:Human Renal Caki1 Cells | Treatment:WT 0.5% O2
F8Sample source:Human Renal Caki1 Cells | Treatment:WT 21% O2
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