Data for (Study ST003214)

(Analysis AN005270)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3
1-Aminocyclopropanecarboxylic acid 1.8212 1.1286 0.0074
1-Methyladenosine 2.1226 0.1580 NA
1-Methyl nicotinamide 1.5108 0.7416 0.0023
2-Amino-2-deoxy-D-mannose 0.3868 1.7090 0.0035
2-Aminophenol 1.4604 1.1201 0.0693
2-Hydroxypyridine 1.2882 1.4004 0.0135
3-Aminoisobutanoic acid 1.3973 1.1970 0.0100
3-Dehydroxycarnitine 1.8221 1.2575 0.0011
3-Hydroxyanthranilic acid 1.4630 1.1440 0.0175
3-Methylhistidine 1.0505 1.5824 0.0075
4-Guanidinobutanoic acid 1.3866 1.5828 0.0026
5-Amino-levulinic acid 0.7732 1.6686 0.0030
5-Aminopentanoic acid 2.2461 0.8091 0.0083
5-Methylcytosine 1.1835 1.5971 0.0204
5^-Methylthioadenosine 0.7021 1.2234 NA
Acetylcholine 1.3225 0.8830 0.0010
Adenine 1.1583 1.7450 0.0129
Adonitol 3.0128 0.3651 0.0004
Alanine 1.5634 1.4500 0.0028
Alanine_13C1 1.7734 1.2620 0.0377
Alanine_13C2 2.4489 0.7821 0.0071
Alanine_13C3 2.4144 0.5640 0.0003
Allothreonine 1.8905 1.0789 0.0043
alpha-Aminoadipic acid 3.3010 0.1491 0.0001
Aminoisobutyric acid 1.2989 1.3564 0.0710
Anserine 1.1015 1.1732 0.0027
Arginine 0.7467 0.1981 2.1337
Asparagine 1.3387 1.4929 0.0040
Asparagine_15N1 1.5324 1.3486 0.0027
beta-Alanine 1.6040 1.4204 0.0018
Betaine 1.6399 1.3883 0.0078
Caffeine 1.0444 1.6217 0.1266
CAR 12:0 1.9823 0.1581 NA
CAR 2:0 1.2864 1.6598 0.0004
CAR DC5:0 1.3667 1.5999 0.0001
Carnitine 1.4378 1.5462 0.0006
Carnosine 1.1354 0.8985 NA
Choline 1.5203 1.4825 0.0026
Choline phosphate 1.2243 1.7062 0.0006
Ciliatine 0.9239 1.5147 0.0276
cis-4-Hydroxy-D-proline 0.8160 1.7610 0.0031
Citrulline 2.6362 0.5215 0.0019
Coenzyme A 0.2169 1.3915 NA
Creatine 1.9215 1.1791 0.0055
Creatinine 1.3021 1.6343 0.0161
Cystathionine 2.4458 0.4153 0.0006
Cysteic acid 0.9278 1.1781 0.0086
Cystine 2.1618 0.1287 NA
Cytidine 1.7213 1.0800 0.0064
D-Alanine 1.6040 1.4204 0.0018
D-Alanine_13C1 1.5564 1.0810 0.0033
D-Alanine_13C2 1.8701 0.5973 0.0005
D-Alanine_13C3 1.7792 0.4156 NA
D-Alanine_15N1 1.6664 0.9999 0.0007
Dethiobiotin 1.8782 1.2061 0.0118
Diethanolamine 1.9902 0.8337 0.2316
Dimethylarginine 1.9091 0.8181 0.0002
D-Ornithine 2.3909 0.8297 0.0024
Ethyl 3-indoleacetate 2.1514 0.9865 0.0266
FAD 0.6536 1.2598 NA
Glucosamine 0.4108 1.8152 0.0044
Glutamine_13C1 1.3138 1.6390 0.0007
Glutamine_13C2 1.2244 1.5815 0.0003
Glutamine_13C3 1.3290 1.6263 0.0022
Glutamine_13C4 1.0311 1.3433 0.0225
Glutamine_13C5 1.1873 1.7339 0.0008
Glutamine_13C5_15N2 2.4657 0.7716 0.0047
Glutamine_15N1 1.3786 1.4660 0.0000
Glutamine_15N2 1.5630 1.4526 0.0001
Glutathione 0.1174 2.7378 0.0187
Glycine 1.1034 1.6157 0.2077
Glycine_13C1 0.9301 1.5321 0.2326
Glyoxylic acid 0.7307 2.0562 0.0237
Guanidinosuccinic acid 0.4249 1.4313 NA
Gulose 0.5011 2.2484 0.0010
Homocysteine 1.7831 0.4713 0.0023
Homoserine 1.9871 1.1311 0.0040
Hypotaurine 0.8561 1.1233 NA
Hypoxanthine 2.0347 1.0975 0.0017
Indole-3-methyl acetate 1.8794 0.9304 0.0400
Inosine 1.6502 1.3872 0.0002
Kynurenine 1.4319 0.6761 NA
Leucine 1.3267 1.3180 0.3565
Leucine_15N1 1.8518 0.9384 0.0764
Lumichrome 0.5864 1.4352 0.0002
Lysine 2.3842 0.8357 0.0013
Methionine 2.2705 0.6720 0.0001
Methylmalonic acid_13C1 1.2851 1.5830 0.0894
Methylmalonic acid_13C2 1.5937 0.9093 0.0545
Methylmalonic acid_13C3 1.5306 1.1016 0.0009
N(2)-Acetyllysine 1.2191 1.4597 0.0016
N-6-Trimethyllysine 2.0006 0.9991 0.0006
N-Acetylasparagine 0.8345 1.3740 0.0006
N-Acetyl-D-galactosamine 1.9019 0.9873 0.1150
N-Acetyl-D-glucosamine 2.1299 0.9597 0.1122
N-Acetyl-mannosamine 1.9021 0.9870 0.1152
NAD+ 0.5241 1.6068 0.0005
NADP+ 0.5649 1.3263 NA
N-ETHYL-5-METHYL-2-(1-METHYLETHYL)-CYCLOHEXANECARBOXAMIDE 1.7055 1.0589 0.0591
N-Formylglycine 1.3608 1.3438 0.0169
Niacinamide 1.3690 1.5978 0.0005
Nicotinamide ribotide 0.2983 1.5263 NA
Nicotinic acid 1.3412 1.3608 0.0132
Nitrotyrosine 0.3910 1.4568 NA
N-METHYL-ALANINE 1.0653 1.0748 0.0098
Norleucine 1.3267 1.3180 0.3566
Norvaline 1.6399 1.3883 0.0078
Octopamine 2.4734 0.7658 0.0048
Ophthalmic acid 1.2440 0.8170 NA
Ornithine 2.3910 0.8296 0.0024
o-Succinylhomoserine NA NA NA
Oxidized glutathione 0.7165 1.2126 NA
Pantothenic acid 1.4029 1.5693 0.0041
Phenylalanine 1.8689 1.2220 0.0015
Phosphoethanolamine 1.7367 0.5725 0.0001
Proline 1.4549 1.0910 0.5060
Pterin 0.5761 1.1590 NA
Pyridoxal 1.3622 1.6024 0.0010
Pyridoxamine 1.9558 0.7745 0.0173
Pyridoxine 1.2603 1.4564 0.1313
Riboflavin 1.1799 0.8650 NA
Ribose 5-phosphate_13C1 0.9370 1.0472 NA
Ribose 5-phosphate_13C2 1.1648 1.2108 0.1084
S-Adenosylhomocysteine 0.8494 1.2380 0.0000
S-Adenosylmethionine 1.0295 1.1029 0.0001
Sarcosine 1.5633 1.4507 0.0021
Serine 1.2932 1.0319 0.7121
Serine_13C1 1.1555 0.8190 1.1288
Taurine 0.9569 1.9070 0.0004
trans-4-Hydroxyproline 0.8112 1.7646 0.0032
Trigonelline 0.5258 2.2304 0.0003
Tryptamine 1.3385 1.3939 0.1363
Tryptophan 2.2756 0.9176 0.0009
Tyramine 1.6645 1.1350 0.2761
Tyrosine 2.5132 0.7395 0.0007
UDP-glucose_13C1 0.4763 1.3928 NA
UDP-glucose_13C2 0.6991 1.2257 NA
UDP-glucose_13C3 1.1539 0.8845 NA
UDP-glucose_13C4 1.4770 0.6423 NA
UDP-glucose_13C5 1.3662 0.4011 0.0008
UDP-glucose_13C6 1.5933 0.2880 NA
UDP-N-acetylgalactosamine 0.6993 1.2255 NA
Valine 1.6399 1.3883 0.0078
Xanthine 0.7611 1.1792 NA
XMP 0.7860 1.1338 NA
Xylose 0.9007 1.8915 0.0663
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Factors:

F1Sample source:C57/BL6 mouse liver tissue | Standards for Standard Curve and Treatment:RquA AAV injected
F2Sample source:C57/BL6 mouse liver tissue | Standards for Standard Curve and Treatment:Vehicle
F3Sample source:Succinate and Fumarate Reagent Mixture | Standards for Standard Curve and Treatment:Measurable Standard Curve
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