Data for (Study ST003888)
(Analysis AN006386)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| 2-Aminoadipic acid_C12 PARENT | 0.8970 | 0.9403 | 0.7905 | 0.4865 | 1.4810 | 1.1411 | 0.8344 | 1.1793 |
| 2-Aminoadipic acid_C13-label-1 | 0.8645 | 1.0691 | 0.5547 | 1.1196 | 1.5312 | 1.1639 | 0.8752 | 0.7124 |
| 2-methylcitrate_C12 PARENT | 0.8611 | 0.2653 | 0.9259 | 1.0871 | 1.5633 | 0.8129 | 1.1627 | 1.3463 |
| 3 5-cAMP_C12 PARENT | 0.6989 | 1.4255 | 1.2359 | 0.6077 | 0.8004 | 1.3368 | 1.1942 | 0.5159 |
| 3 5-cAMP_C13-label-1 | 0.7216 | 0.8505 | 1.1141 | 1.0486 | 1.1076 | 1.1422 | 0.9912 | 1.0803 |
| 3 5-cAMP_C13-label-8 | 1.0490 | 0.9510 | NA | NA | NA | NA | NA | NA |
| 3-Cresotinic acid_C12 PARENT | 1.0364 | 1.1232 | 0.5524 | 1.0823 | 1.2162 | 0.8812 | 1.0115 | 1.0855 |
| 3-Cresotinic acid_C13-label-1 | 1.1373 | 0.8801 | 0.6321 | 0.9949 | 1.1370 | 0.8823 | 0.7289 | 1.3416 |
| 4-Guanidinobutyrate_C12 PARENT | 0.4704 | 0.7906 | 0.6981 | 0.6700 | 0.7609 | 0.9015 | 1.8675 | 1.6903 |
| 4-Guanidinobutyrate_C13-label-1 | 0.4163 | 0.2001 | 0.9169 | 0.8752 | 0.8159 | 0.6583 | 1.8887 | 1.5363 |
| 5-Deoxy-5-(methylthio)adenosine_C12 PARENT | 0.8753 | 1.0786 | 1.8674 | 0.7536 | 0.5634 | 1.0539 | 0.9703 | 0.8435 |
| 5-Deoxy-5-(methylthio)adenosine_C13-label-1 | 0.4728 | 1.4657 | 1.7427 | 0.6062 | 0.5148 | 0.8396 | 1.4359 | 0.8504 |
| Acetyl-arginine_C12 PARENT | 0.6099 | 1.3819 | 1.3833 | 0.7874 | 0.7885 | 1.3150 | 0.6942 | 0.8337 |
| Acetyl-arginine_C13-label-1 | 0.6384 | 1.3396 | 1.6793 | 0.8531 | 1.0966 | 0.8754 | 0.5669 | 0.7966 |
| Acetyl-arginine_C13-label-6 | NA | NA | 0.9566 | 0.8261 | NA | NA | 1.0382 | 1.0896 |
| Acetylcholine_C12 PARENT | 0.9861 | 1.5247 | 0.9620 | 0.6087 | 0.7462 | 1.5096 | 0.9112 | 0.5450 |
| Acetylcholine_C13-label-1 | 0.8188 | 1.5600 | 0.9869 | 0.4952 | 0.6789 | 1.5774 | 1.0467 | 0.5624 |
| Aconitate_C12 PARENT | 1.0028 | 1.2753 | 0.9465 | 1.3340 | 0.7471 | 1.1991 | 0.6905 | 0.8207 |
| Aconitate_C13-label-1 | NA | 1.0404 | 0.9262 | NA | NA | 1.0058 | 1.1290 | NA |
| Adenine_C12 PARENT | 0.4436 | 2.1063 | 0.7736 | 0.7334 | 0.7160 | 1.3120 | 1.0528 | 0.5578 |
| Adenine_C13-label-1 | 0.7607 | 1.6371 | 0.8913 | 0.7867 | 0.8424 | 1.0388 | 1.0468 | 0.8524 |
| Adenine_C13-label-3 | 0.8960 | 1.2500 | 0.7634 | 0.8569 | 1.1146 | 0.8110 | 0.8044 | 1.3556 |
| Adenosine_C12 PARENT | 0.5722 | 2.6716 | 0.6450 | 0.6538 | 0.6219 | 0.9802 | 0.9962 | 0.5895 |
| Adenosine_C13-label-1 | 0.3384 | 2.4797 | 0.6255 | 0.6526 | 0.6350 | 1.0835 | 1.4933 | 0.4086 |
| Adenosine_C13-label-2 | 0.4947 | 2.5499 | 0.5231 | 0.7078 | 0.5376 | 0.8457 | 1.2097 | 0.7099 |
| ADP_C12 PARENT | 1.6546 | 1.7068 | 0.5623 | 0.9037 | 0.6747 | 1.1683 | 0.8234 | 0.5539 |
| ADP_C13-label-1 | 1.4223 | 1.6933 | 0.4226 | 0.8268 | 0.9850 | 1.2840 | 0.6511 | 0.6131 |
| ADP_C13-label-2 | 1.3495 | 1.8115 | 0.3435 | 0.7732 | 0.6707 | 1.4658 | 1.0100 | 0.3596 |
| ADP_C13-label-3 | 1.0079 | 1.0153 | NA | NA | NA | 0.9768 | NA | NA |
| ADP-ribose_C12 PARENT | 1.5769 | 2.0805 | 0.3408 | 0.5123 | 0.9167 | 1.1673 | 0.8852 | 0.4114 |
| ADP-ribose_C13-label-1 | 1.2171 | 1.5557 | 0.2752 | 0.3661 | 0.8284 | 0.9173 | 0.8880 | NA |
| ADP-ribose_C13-label-11 | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| ADP-ribose_C13-label-2 | NA | 1.4325 | NA | 0.8580 | 0.9723 | 0.0872 | 0.8926 | NA |
| Alanine_C12 PARENT | 0.5977 | 0.9826 | 1.0447 | 0.7502 | 1.0261 | 1.0131 | 1.2585 | 1.1823 |
| Alanine_C13-label-1 | 0.8376 | 1.1757 | 1.2576 | 0.9545 | 0.9704 | 0.7565 | 1.0654 | 1.0039 |
| Alanine_C13-label-2 | 0.5043 | 1.1512 | 1.6420 | 0.7598 | 0.4462 | 1.2439 | 1.6353 | 0.5547 |
| Alanine_C13-label-3 | 0.9454 | 0.8176 | 1.3861 | 1.2407 | 0.7700 | 0.8781 | 0.9233 | 1.1537 |
| AMP_C12 PARENT | 1.9413 | 1.3062 | 0.6373 | 0.6344 | 1.1107 | 1.1140 | 0.8292 | 0.4989 |
| AMP_C13-label-1 | 1.7859 | 1.3933 | 0.6142 | 0.5398 | 1.2790 | 1.0342 | 1.0686 | 0.3279 |
| AMP_C13-label-2 | 1.9034 | 1.6356 | 0.5984 | 0.6346 | 1.1309 | 0.8463 | 0.8667 | 0.4834 |
| AMP_C13-label-3 | 1.2075 | 0.7116 | NA | NA | 1.1080 | 0.8696 | 0.8959 | NA |
| AMP_C13-label-5 | 1.0000 | NA | NA | NA | NA | NA | NA | NA |
| Anserine_C12 PARENT | 1.0404 | 1.2814 | 0.9429 | 0.8014 | 0.8255 | 1.2262 | 0.8624 | 0.9144 |
| Anserine_C13-label-1 | 0.7614 | 0.3724 | 0.8709 | 1.1138 | 1.9518 | 0.3021 | 1.4332 | 1.3019 |
| Anserine_C13-label-2 | 0.7820 | 1.4576 | 0.9651 | 0.7211 | 0.7924 | 1.3134 | 0.9763 | 0.7969 |
| Arginine_C12 PARENT | 1.3733 | 0.6405 | 0.8244 | 1.9617 | 0.4374 | 1.0975 | 0.9506 | 1.0500 |
| Arginine_C13-label-1 | 0.5152 | 0.3643 | 0.7847 | 1.2317 | 2.0663 | 0.7322 | 0.7368 | 1.4357 |
| Arginino-succinate_C12 PARENT | 0.4016 | 1.1208 | 1.0513 | 0.7895 | 1.5813 | 1.2364 | 0.4638 | 1.0211 |
| Arginino-succinate_C13-label-1 | 0.5582 | 1.0264 | 0.8818 | 0.9119 | 1.7095 | 0.9427 | 0.5602 | 0.8260 |
| Arginino-succinate_C13-label-2 | NA | 0.9582 | 1.0414 | 1.1189 | NA | 1.0850 | 0.8360 | NA |
| Asparagine_C12 PARENT | 1.0298 | 1.4375 | 1.2008 | 0.7407 | 0.8387 | 0.8796 | 0.9590 | 0.8883 |
| Asparagine_C13-label-1 | 1.0594 | 1.2793 | 1.2180 | 0.7924 | 0.5690 | 1.1535 | 1.0260 | 0.8730 |
| Aspartate_C12 PARENT | 0.9537 | 1.3082 | 1.1600 | 0.5519 | 0.8129 | 1.0871 | 0.6510 | 1.2946 |
| Aspartate_C13-label-1 | 0.8505 | 1.1397 | 1.1879 | 0.9954 | 1.1304 | 0.7408 | 0.8308 | 1.1200 |
| Aspartate_C13-label-3 | NA | 1.0215 | 1.0259 | 0.7897 | 1.9454 | 0.7546 | 0.2982 | 0.7619 |
| ATP_C12 PARENT | 0.5236 | 1.6763 | 0.7034 | 0.8289 | 0.8478 | 1.5546 | 0.6727 | 0.8393 |
| ATP_C13-label-1 | 0.8998 | 1.5756 | 0.5184 | 0.8085 | 0.8070 | 1.4491 | 0.9304 | 0.7849 |
| ATP_C13-label-2 | 1.0920 | 1.3918 | 0.5289 | 1.1039 | 0.6933 | 1.5840 | 0.7086 | 0.6938 |
| ATP_C13-label-3 | 0.8203 | 0.9193 | 0.7471 | 1.0935 | 0.9774 | 1.3385 | 1.1255 | 0.8065 |
| Carnitine_C12 PARENT | 0.8185 | 1.1123 | 1.0640 | 1.1149 | 1.0553 | 0.9002 | 0.8950 | 1.0291 |
| Carnitine_C13-label-1 | 0.9658 | 1.0471 | 1.1658 | 1.0125 | 0.8132 | 1.1014 | 0.8475 | 1.0278 |
| Carnitine_C13-label-2 | 0.9564 | 1.0719 | 1.0634 | 1.2946 | 1.0576 | 0.7825 | 0.8400 | 1.0225 |
| Carnosine_C12 PARENT | 1.2966 | 1.3303 | 0.7708 | 0.8263 | 0.8022 | 1.2840 | 0.7594 | 0.8578 |
| Carnosine_C13-label-1 | 1.1982 | 0.3379 | 1.2298 | 0.4305 | 1.0043 | 1.5710 | 0.8277 | 1.2213 |
| Carnosine_C13-label-2 | 1.4689 | 1.5351 | 1.0209 | 0.8683 | 0.6961 | 1.3727 | 0.6829 | 0.3560 |
| CDP-choline_C12 PARENT | 0.6469 | 0.8290 | 1.1461 | 0.5109 | 1.3605 | 1.1759 | 1.0974 | 1.0022 |
| CDP-choline_C13-label-1 | 0.7629 | 1.4349 | 1.0042 | 0.7260 | 0.7912 | 1.0228 | 1.1120 | 1.0132 |
| CDP-choline_C13-label-10 | NA | NA | NA | NA | NA | NA | 1.0000 | NA |
| CDP-choline_C13-label-2 | 0.6910 | 1.3875 | 0.8388 | 0.6655 | 1.6277 | 0.7504 | 1.0453 | 0.6615 |
| CDP-ethanolamine_C12 PARENT | 1.1392 | 1.0988 | 0.7813 | 0.6760 | 1.2158 | 0.8659 | 0.8642 | 1.2745 |
| CDP-ethanolamine_C13-label-1 | 1.1429 | 0.7718 | 0.9194 | 0.8491 | 1.1926 | 0.8040 | 0.8557 | 1.2644 |
| CDP-ethanolamine_C13-label-2 | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| Choline_+Hac_C12 PARENT | 3.2509 | 0.8791 | 0.9614 | 0.6633 | 0.6114 | 0.7530 | 0.9408 | 0.5083 |
| Choline_+Hac_C13-label-1 | 3.2936 | 0.8400 | 0.9087 | 0.6205 | 0.6591 | 0.9185 | 0.7315 | 0.5353 |
| Citrulline_C12 PARENT | 1.0457 | 1.0508 | 1.0657 | 1.1948 | 0.8513 | 1.2334 | 0.6943 | 0.8652 |
| Citrulline_C13-label-1 | 1.0024 | 1.0553 | 0.8572 | 1.2249 | 1.1595 | 1.0368 | 0.6775 | 0.9796 |
| Citrulline_C13-label-2 | 0.8506 | 0.9952 | 0.7094 | 1.5874 | 0.7723 | 1.0909 | 0.9907 | 1.0729 |
| Citrulline_C13-label-3 | 0.7700 | 1.3229 | 0.7153 | 0.9907 | 0.7003 | 1.2991 | 1.0788 | 0.9233 |
| Citrulline_C13-label-4 | NA | NA | NA | NA | NA | NA | 1.0000 | NA |
| CMP_C12 PARENT | 1.4012 | 0.8001 | 0.5560 | 0.8710 | 1.3355 | 1.0826 | 1.2127 | 0.7738 |
| CMP_C13-label-1 | 1.0000 | NA | NA | NA | NA | NA | NA | NA |
| Creatine_C12 PARENT | 1.0641 | 1.1098 | 0.9527 | 0.9216 | 0.9996 | 1.0167 | 0.9863 | 0.9341 |
| Creatine_C13-label-1 | 1.0602 | 1.1021 | 0.9440 | 0.9139 | 1.0059 | 1.0190 | 0.9952 | 0.9409 |
| Creatine_C13-label-2 | 1.1400 | 0.9399 | 0.9767 | 0.7867 | 1.0524 | 1.0723 | 1.0098 | 0.9890 |
| Creatine phosphate_C12 PARENT | 2.5391 | 1.2192 | 0.6015 | 0.5327 | 0.7983 | 0.4135 | 1.6001 | 0.7145 |
| Creatine phosphate_C13-label-1 | 0.3753 | 0.5609 | 1.3302 | 1.4931 | 1.1457 | 0.9326 | 0.9897 | 1.1901 |
| Creatinine_C12 PARENT | 0.6643 | 1.1227 | 1.3627 | 0.6054 | 0.8102 | 1.1320 | 1.1309 | 1.0148 |
| Creatinine_C13-label-1 | 0.7467 | 1.3209 | 1.3579 | 0.6287 | 1.0877 | 0.7645 | 1.3212 | 0.7246 |
| Creatinine_C13-label-2 | 0.7576 | 1.0631 | 1.0592 | 0.4173 | 0.9157 | 1.0985 | 1.3276 | 1.1664 |
| Cystathionine_C12 PARENT | 0.5034 | 0.5229 | 0.5475 | 0.5998 | 1.4824 | 1.5626 | 0.9637 | 1.4112 |
| Cytidine_C12 PARENT | 0.9092 | 1.6687 | 1.2455 | 0.4514 | 0.6843 | 0.8716 | 1.0055 | 1.0354 |
| Cytosine_C12 PARENT | 0.8601 | 1.4820 | 1.3997 | 1.1331 | 0.7697 | 1.0200 | 0.6707 | 0.6701 |
| Cytosine_C13-label-1 | 0.8667 | 1.4259 | 1.3933 | 1.0128 | 0.7548 | 1.0246 | 0.6976 | 0.7993 |
| Deoxycarnitine_C12 PARENT | 0.6411 | 0.6100 | 1.4340 | 0.7248 | 0.7842 | 1.0361 | 1.0616 | 1.5926 |
| Deoxycarnitine_C13-label-1 | 1.0106 | 0.9101 | 1.0192 | 1.1109 | 1.0946 | 0.8209 | 0.7729 | 1.2914 |
| Deoxycarnitine_C13-label-2 | 0.8508 | 1.1387 | 1.1405 | 0.9793 | 1.2835 | 0.8556 | 0.5784 | 1.1050 |
| Deoxycytidine_C12 PARENT | 0.7000 | 1.4219 | 1.4612 | 1.0541 | 0.7310 | 1.1108 | 0.7337 | 0.7289 |
| Deoxycytidine_C13-label-1 | 0.4796 | 0.5178 | 1.8757 | 1.5993 | 0.4273 | 0.6065 | 0.8734 | 1.2512 |
| Deoxycytidine_C13-label-2 | 1.1968 | 1.4153 | NA | 1.0650 | 0.9196 | 0.6008 | NA | 0.8667 |
| Diethanolamine_C12 PARENT | 1.1321 | 1.4406 | 1.0179 | 0.6893 | 0.8484 | 0.9972 | 0.9807 | 0.8431 |
| Diethanolamine_C13-label-1 | 1.1967 | 1.5344 | 1.0339 | 0.8586 | 0.7546 | 1.0832 | 0.9546 | 0.5862 |
| Dimethyl-arginine_C12 PARENT | 0.6385 | 0.8171 | 1.1090 | 0.8867 | 1.4500 | 1.2431 | 0.8569 | 0.8234 |
| Dimethyl-arginine_C13-label-1 | 0.6598 | 0.8146 | 1.0948 | 0.8222 | 0.9070 | 1.3309 | 1.0644 | 1.1337 |
| Glucose 6-phosphate_C12 PARENT | 0.8737 | 0.8182 | 0.9210 | 1.2201 | 0.7556 | 1.4961 | 0.6913 | 1.1246 |
| Glucose 6-phosphate_C13-label-1 | 1.0759 | 0.7111 | 1.1887 | 1.0517 | 1.0395 | 0.9943 | 1.1031 | 0.9203 |
| Glucose 6-phosphate_C13-label-2 | 0.4185 | 0.6306 | 2.7089 | 0.6083 | 0.3939 | 0.5917 | 1.7361 | 0.7495 |
| Glucose 6-phosphate_C13-label-3 | 0.5774 | 0.7200 | 2.1408 | 1.2039 | 0.3972 | 0.7432 | 1.6567 | 0.7918 |
| Glucose 6-phosphate_C13-label-4 | 0.8088 | 0.8296 | 1.3501 | 0.4676 | 0.8448 | 0.6822 | 1.6789 | 0.7939 |
| Glucose 6-phosphate_C13-label-5 | NA | 1.0473 | 0.9567 | 1.1441 | NA | 0.7148 | 1.6579 | 0.5688 |
| Glucose 6-phosphate_C13-label-6 | 0.6581 | 0.4664 | 1.2534 | 2.2143 | 0.7065 | 0.7483 | 1.1461 | 1.1491 |
| Glutamate_C12 PARENT | 0.7868 | 1.0440 | 0.7956 | 1.1384 | 1.4715 | 1.1119 | 1.2064 | 0.4084 |
| Glutamate_C13-label-1 | 0.8952 | 1.0533 | 0.9025 | 1.0311 | 1.2522 | 0.6906 | 1.0477 | 1.1433 |
| Glutamate_C13-label-2 | 0.8111 | 1.1281 | 1.3923 | 0.9906 | 0.8000 | 0.9989 | 0.6762 | 1.1561 |
| Glutamate_C13-label-3 | 0.9310 | 0.9066 | 1.0514 | 1.4165 | 1.3710 | 0.7712 | 1.1967 | 0.5230 |
| Glutamate_C13-label-4 | 2.0912 | 1.3967 | 0.7157 | 0.8827 | 0.2636 | 0.9798 | 0.7983 | 1.4266 |
| Glutamine_C12 PARENT | 2.2925 | 0.9879 | 0.9345 | 0.7475 | 0.6804 | 0.8807 | 1.1668 | 0.6384 |
| Glutamine_C13-label-1 | 0.6632 | 1.0787 | 1.6816 | 0.2971 | 1.1297 | 1.5735 | 0.2861 | 0.9064 |
| Glutamine_C13-label-2 | 0.5008 | 1.5272 | 1.1964 | 0.8007 | 0.5843 | 1.3950 | 1.0736 | 0.7046 |
| Glutamine_C13-label-3 | 0.5086 | 1.6176 | 0.8809 | 0.9515 | 0.5526 | 1.2325 | 1.3461 | 0.7552 |
| Glutamine_C13-label-4 | 0.6312 | 1.1026 | 1.2426 | 0.9567 | 1.1061 | 1.1237 | 1.0722 | 0.6743 |
| Glutathione_C12 PARENT | 0.4556 | 1.0350 | 1.0387 | 1.3137 | 1.0395 | 1.2825 | 0.8387 | 0.8725 |
| Glutathione_C13-label-1 | 1.0013 | 0.9752 | 0.8489 | 1.0468 | 1.1580 | 1.1692 | 0.6530 | 1.0659 |
| Glutathione_C13-label-2 | 0.8685 | 1.1336 | 0.9896 | 1.1263 | 0.8436 | 1.0831 | 1.1896 | 0.8050 |
| Glutathione_C13-label-3 | 0.9886 | 1.2448 | 0.7639 | 1.0766 | 1.2435 | 0.8754 | 0.8858 | 0.9062 |
| Glycerol 3-phosphate_C12 PARENT | 1.1565 | 1.0412 | 0.3960 | 1.2699 | 1.0399 | 1.2791 | 1.2465 | 0.6017 |
| Glycerol 3-phosphate_C13-label-1 | 0.7513 | 1.1123 | 1.0477 | 1.1079 | 0.8343 | 1.0478 | 1.1447 | 0.9345 |
| Glycerol 3-phosphate_C13-label-2 | 0.1753 | 0.7083 | 3.0493 | 0.6788 | 0.3741 | 0.7272 | 1.6974 | 0.5050 |
| Glycerol 3-phosphate_C13-label-3 | 0.6328 | 0.7717 | 1.7223 | 1.6287 | 0.7574 | 0.6450 | 1.0816 | 1.0007 |
| Glycerophosphocholine_C12 PARENT | 0.9149 | 1.5351 | 0.9599 | 0.5131 | 0.8529 | 1.0744 | 0.9434 | 1.0184 |
| Glycerophosphocholine_C13-label-1 | 0.8993 | 1.1904 | 1.2498 | 0.9079 | 0.9008 | 1.0928 | 0.8731 | 0.8351 |
| Glycerophosphocholine_C13-label-2 | 1.2253 | 0.8478 | 0.7729 | 0.6909 | 0.9871 | 1.0745 | 1.0264 | 1.3117 |
| Glycerophosphocholine_C13-label-3 | 0.7727 | 1.8420 | 1.3730 | 1.1738 | 0.7864 | 0.7973 | 0.7092 | 0.5710 |
| Glycine_C12 PARENT | 1.6026 | 1.3950 | 1.2026 | 0.9997 | 0.5892 | 0.8234 | 0.9314 | 0.6726 |
| Glycine_C13-label-1 | 0.7757 | 1.3573 | 1.6965 | 1.1425 | 0.6373 | 0.8175 | 0.9363 | 0.7299 |
| Glycine_C13-label-2 | 1.0952 | 1.1129 | 1.3351 | 0.8820 | 0.8754 | 0.6848 | 1.0034 | 0.8626 |
| GMP_C12 PARENT | 2.0393 | 1.2933 | 0.1944 | 0.1544 | 1.4391 | 0.4138 | 0.7534 | NA |
| GMP_C13-label-1 | 0.4461 | 0.5843 | 1.4156 | 1.1770 | 1.3426 | 0.6318 | 0.6169 | 1.6759 |
| Guanidineacetic acid_C12 PARENT | 0.9620 | 0.9481 | 1.2118 | 1.0806 | 1.1571 | 0.6763 | 0.9169 | 1.1241 |
| Guanine_C12 PARENT | 0.7223 | 1.1036 | 1.2554 | 0.9406 | 0.8916 | 1.1667 | 1.0359 | 0.8055 |
| Guanine_C13-label-1 | 0.5643 | 1.0906 | 1.1156 | 2.7831 | 0.7846 | 0.9670 | 0.4077 | 0.6087 |
| Guanine_C13-label-5 | 0.5569 | 1.2685 | 1.0832 | 0.8920 | 1.2034 | 1.6662 | 0.0979 | NA |
| Guanosine_C12 PARENT | 0.7169 | 1.7405 | 1.2086 | 0.8457 | 0.5743 | 1.2024 | 0.9797 | 0.6050 |
| Histamine_C12 PARENT | 3.0554 | 0.5941 | 1.5938 | 0.1240 | 0.5251 | 0.6290 | 1.6952 | 0.3576 |
| Histamine_C13-label-1 | 0.7216 | 0.8706 | 1.2703 | 1.2410 | 0.9349 | 0.9171 | 0.9795 | 1.1018 |
| Histamine_C13-label-2 | 0.6625 | 1.2080 | 1.2707 | 0.8039 | 0.6452 | 1.1488 | 1.0416 | 1.0902 |
| Hypotaurine_C12 PARENT | 0.6451 | 0.5732 | 1.1463 | 1.1941 | 0.8416 | 0.6298 | 0.9698 | 2.0237 |
| Hypotaurine_C13-label-1 | 1.0679 | NA | 0.5065 | 0.6579 | 0.7521 | 0.8107 | 1.5390 | 1.1264 |
| Hypoxanthine_C12 PARENT | 1.7354 | 1.1365 | 0.6549 | 1.1491 | 0.8022 | 0.7280 | 1.4508 | 0.6497 |
| Hypoxanthine_C13-label-1 | 1.5024 | 2.0454 | 0.5598 | 0.9644 | 0.8215 | 0.6904 | 0.9907 | 0.5388 |
| IMP_C12 PARENT | 2.6428 | 2.8676 | 0.1885 | 0.2980 | 0.6912 | 0.8960 | 0.3948 | 0.1024 |
| IMP_C13-label-1 | 2.4636 | 2.6064 | 0.2728 | 0.3968 | 0.5087 | 0.6889 | 1.1802 | 0.0947 |
| IMP_C13-label-2 | 2.3024 | 1.7992 | 0.1847 | 0.1564 | 1.3576 | 0.3504 | 0.8669 | 0.0889 |
| IMP_C13-label-3 | 0.8902 | 1.1563 | NA | NA | 2.2226 | 0.2524 | 0.8184 | NA |
| IMP_C13-label-4 | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| Inosine_C12 PARENT | 1.0458 | 2.1056 | 0.8127 | 0.3769 | 1.0217 | 0.8745 | 1.0116 | 0.5791 |
| Inosine_C13-label-1 | 1.3022 | 1.7847 | 0.6099 | 0.4049 | 0.9853 | 0.9366 | 1.5907 | 0.3398 |
| Inosine_C13-label-4 | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| Isoleucine_C12 PARENT | 0.9897 | 1.5019 | 0.9519 | 1.0001 | 1.1873 | 0.8977 | 0.5865 | 0.8307 |
| Isoleucine_C13-label-1 | 1.0126 | 1.2612 | 0.9626 | 0.9615 | 1.1457 | 1.0385 | 0.7079 | 0.8499 |
| Isoleucine_C13-label-2 | 0.9892 | 1.1607 | 0.7363 | 1.0504 | 1.1082 | 1.2482 | 1.0402 | 0.5542 |
| Kynurenine_C12 PARENT | 0.8447 | 0.7986 | 1.3931 | 0.4407 | 1.0526 | 1.3442 | 0.8189 | 1.0841 |
| Leucine_C12 PARENT | 1.2487 | 1.5208 | 0.7687 | 0.7010 | 0.9324 | 0.6677 | 1.0307 | 1.1345 |
| Leucine_C13-label-1 | 0.8899 | 1.4945 | 1.0173 | 0.7140 | 1.3271 | 0.9503 | 0.7666 | 0.7033 |
| Lysine_C12 PARENT | 1.1497 | 0.9170 | 1.1233 | 0.9325 | 0.9859 | 1.3036 | 0.5492 | 0.9721 |
| Lysine_C13-label-1 | 0.3810 | 0.6174 | 0.9134 | 0.6279 | 2.2391 | 1.1288 | 0.8301 | 0.9242 |
| Lysine_C13-label-2 | 0.5785 | 0.4402 | 1.1147 | 0.5997 | 1.8244 | 1.4570 | 0.9390 | 0.7540 |
| Methionine_C12 PARENT | 0.7087 | 1.4563 | 0.9785 | 0.8440 | 1.0113 | 1.0512 | 0.7080 | 1.0621 |
| Methionine_C13-label-1 | 0.7427 | 1.4583 | 0.6970 | 1.0192 | 0.9854 | 1.0871 | 0.7564 | 1.0952 |
| Methionine_C13-label-2 | NA | 1.0538 | NA | NA | NA | NA | 0.8385 | NA |
| Methionine sulfoxide_C12 PARENT | 0.5453 | 1.4513 | 1.4453 | 0.9524 | 0.8153 | 1.1913 | 0.5511 | 0.8767 |
| Methyl-histidine_C12 PARENT | 0.6148 | 1.9020 | 1.4135 | 0.4737 | 0.4236 | 1.5638 | 0.6034 | 0.6667 |
| Methyl-histidine_C13-label-1 | 0.7206 | 2.0527 | 1.2370 | 0.5100 | 0.4603 | 1.5212 | 0.5358 | 0.6356 |
| NAD_C12 PARENT | 0.7336 | 1.3184 | 1.1667 | 0.9897 | 0.8695 | 0.8039 | 0.8072 | 1.2563 |
| NAD_C13-label-1 | 0.8530 | 1.1892 | 1.1948 | 0.9249 | 0.7828 | 0.8767 | 1.0484 | 1.1190 |
| NAD_C13-label-14 | NA | NA | NA | NA | 0.9142 | NA | NA | 1.0858 |
| NAD_C13-label-2 | 0.8226 | 0.9624 | 1.1894 | 1.0494 | 1.0180 | 0.9680 | 0.8642 | 1.1017 |
| NAD_C13-label-3 | 0.8299 | 1.2017 | 1.1645 | 1.1242 | 0.9478 | 0.9493 | 1.0281 | 0.7762 |
| NAD_C13-label-4 | 0.9583 | 1.2072 | 1.3420 | 0.7380 | 0.9714 | 1.0249 | 0.9212 | 0.7373 |
| NAD_C13-label-5 | NA | NA | NA | 1.3641 | 0.6359 | NA | NA | NA |
| NAD_C13-label-8 | NA | NA | NA | NA | NA | NA | NA | NA |
| Nicotinamide_C12 PARENT | 0.9903 | 1.2610 | 0.7963 | 1.8386 | 1.0573 | 0.7224 | 0.8928 | 0.6733 |
| Nicotinamide_C13-label-1 | 1.2439 | 2.3510 | 0.4508 | 0.6819 | 0.9472 | 0.9132 | 0.9013 | 0.4093 |
| Nicotinamide_C13-label-2 | 1.2703 | 2.1172 | 0.4742 | 0.3435 | 0.8450 | 1.1155 | 0.8387 | 0.2040 |
| N-Methyl-L-glutamate_C12 PARENT | 1.6259 | 1.2915 | 0.7210 | 0.9601 | 0.6833 | 1.4966 | 0.9239 | 0.3435 |
| O-Phosphorylethanolamine_C12 PARENT | 0.8611 | 1.1035 | 0.7835 | 0.9647 | 1.1421 | 1.0845 | 0.8476 | 1.0984 |
| O-Phosphorylethanolamine_C13-label-1 | 0.7522 | 1.1269 | 1.0760 | 0.9425 | 1.1464 | 1.0700 | 0.8506 | 0.9275 |
| Ophthalmate_C12 PARENT | 0.6712 | 1.0668 | 1.0956 | 0.5923 | 0.9690 | 1.5115 | 1.1408 | 0.6561 |
| Ornithine_C12 PARENT | 0.9950 | 0.6820 | 0.7137 | 0.7869 | 1.5111 | 1.0087 | 0.8796 | 1.3012 |
| Phenylacetaldehyde_C12 PARENT | 0.9446 | 1.1495 | 1.6982 | 0.7890 | 0.6309 | 0.9269 | 0.6111 | 1.2283 |
| Phenylacetaldehyde_C13-label-1 | 0.8537 | 1.2350 | 1.6135 | 0.4629 | 0.4253 | 0.9843 | 0.9851 | 1.3326 |
| Phenylacetaldehyde_C13-label-8 | 0.7826 | 1.1869 | 1.1158 | 0.9120 | 1.1770 | 0.7982 | 0.9799 | 1.0028 |
| Phenylalanine_C12 PARENT | 0.7628 | 1.2711 | 0.7172 | 0.9104 | 0.9546 | 1.1247 | 0.9482 | 1.1520 |
| Phenylalanine_C13-label-1 | 0.8922 | 1.6221 | 1.0268 | 0.6298 | 1.2025 | 0.9185 | 0.8987 | 0.6737 |
| Phenylalanine_C13-label-2 | 0.8129 | 1.7042 | 1.1345 | 0.4804 | 1.2465 | 0.8846 | 0.6932 | 0.8337 |
| Phosphocholine_C12 PARENT | 1.0423 | 1.4147 | 1.0650 | 0.4478 | 0.8412 | 1.2914 | 0.9630 | 0.7513 |
| Phosphocholine_C13-label-1 | 0.7844 | 1.4581 | 1.4690 | 0.3005 | 0.7840 | 1.4239 | 0.9827 | 0.5399 |
| Proline_C12 PARENT | 1.1936 | 0.9554 | 0.7006 | 0.5060 | 0.9855 | 0.8269 | 1.5621 | 1.2463 |
| Proline_C13-label-1 | 1.0299 | 1.1525 | 0.7808 | 1.0117 | 0.8164 | 1.1997 | 0.9015 | 1.0455 |
| Proline_C13-label-2 | 0.6478 | 1.0276 | 1.0399 | 0.5581 | 0.5059 | 1.2782 | 1.9645 | 0.7842 |
| Pyridoxal_C12 PARENT | 0.5853 | 1.0980 | 1.3235 | 0.8814 | 0.8346 | 0.9977 | 0.8736 | 1.2819 |
| Pyridoxal_C13-label-1 | 0.9793 | 1.0330 | 1.1782 | NA | 0.9250 | 0.9769 | 1.1819 | 0.5690 |
| Pyridoxal_C13-label-6 | NA | 0.8892 | NA | NA | 1.0031 | NA | 1.0538 | NA |
| S-Adenosyl-homocysteine_C12 PARENT | 0.8266 | 2.1050 | 1.3347 | 0.5048 | 0.4186 | 1.3386 | 0.8514 | 0.3088 |
| S-Adenosyl-homocysteine_C13-label-1 | NA | 0.7940 | 1.4399 | 1.1426 | NA | 1.2414 | NA | NA |
| S-Adenosylmethionine_C12 PARENT | 0.7714 | 0.8748 | 1.1794 | 0.8283 | 0.8478 | 0.8812 | 1.2204 | 1.3564 |
| S-Adenosylmethionine_C13-label-1 | 0.7328 | 0.9392 | 1.1032 | 1.3205 | 1.1350 | 0.8307 | 0.9977 | 0.9947 |
| S-Adenosylmethionine_C13-label-2 | 1.0517 | 0.9043 | 1.4482 | 0.7227 | 0.7187 | 0.9120 | 0.9633 | 1.2457 |
| Serine_C12 PARENT | 0.9428 | 1.1531 | 1.0959 | 0.8445 | 1.0914 | 1.1919 | 0.8298 | 0.7518 |
| Serine_C13-label-1 | 0.9742 | 1.2844 | 1.0098 | 0.9470 | 0.8987 | 1.1061 | 0.9833 | 0.7578 |
| Succinyl-CoA_C12 PARENT | 0.8090 | 0.8070 | 0.9703 | 1.2433 | 1.0475 | 0.6035 | 0.6914 | 1.7042 |
| Succinyl-CoA_C13-label-1 | 0.9825 | 0.7223 | 1.2966 | 1.0032 | 1.0502 | 0.7680 | 0.7072 | 1.5568 |
| Taurine_C12 PARENT | 1.0083 | 0.9884 | 0.8892 | 1.1093 | 1.0590 | 0.9506 | 0.9530 | 1.0603 |
| Taurine_C13-label-1 | 1.3487 | 1.3754 | 0.9790 | 1.4284 | 1.0158 | 0.7734 | 0.5197 | 0.7423 |
| Taurine_C13-label-2 | 1.5864 | 1.1511 | 0.5607 | 1.3034 | 0.7845 | 0.9219 | 1.0498 | 0.7585 |
| Thiamine pyrophosphate_C12 PARENT | 0.7759 | 1.3539 | 1.0100 | 0.7160 | 0.7516 | 1.1571 | 1.1302 | 0.9457 |
| Threonine_C12 PARENT | 0.7083 | 1.5211 | 1.0783 | 0.8446 | 1.3255 | 0.6711 | 0.7308 | 1.0123 |
| Threonine_C13-label-1 | 1.1262 | 1.2853 | 0.8840 | 1.0974 | 1.1603 | 0.9605 | 0.7512 | 0.7525 |
| Trimethylglycine (Betaine)_C12 PARENT | 1.0464 | 1.0246 | 0.9881 | 1.0695 | 1.0635 | 0.8654 | 0.9399 | 1.0446 |
| Trimethylglycine (Betaine)_C13-label-1 | 1.3102 | 0.8894 | 1.2591 | 0.8573 | 1.3536 | 0.9166 | 0.5317 | 0.9120 |
| Trimethylglycine (Betaine)_C13-label-2 | 1.0734 | 0.8851 | 0.7729 | 1.1604 | 1.0885 | 0.9575 | 1.0398 | 1.0684 |
| Tryptophan_C12 PARENT | 0.7168 | 1.2377 | 1.3989 | 0.6883 | 1.1409 | 0.9193 | 0.6550 | 1.0923 |
| Tryptophan_C13-label-1 | 0.8926 | 0.9155 | 1.4740 | 0.9057 | 1.0442 | 0.8592 | 0.7727 | 1.1338 |
| Tryptophan_C13-label-2 | 0.9004 | 1.3867 | 1.3984 | 0.8730 | 0.8009 | 0.7792 | 0.7971 | 1.0591 |
| Tryptophan_C13-label-6 | 0.5513 | 0.9382 | 1.0455 | 0.9608 | 0.8247 | 1.3032 | 0.5779 | 1.5618 |
| Tryptophan_C13-label-7 | 0.7431 | 1.0589 | 0.9367 | 0.8229 | 0.8643 | 0.6287 | 1.4507 | 2.0242 |
| Tyrosine_C12 PARENT | 0.7949 | 1.5314 | 1.0795 | 0.7708 | 0.9808 | 0.8400 | 0.6063 | 1.2502 |
| Tyrosine_C13-label-1 | 0.8856 | 1.3200 | 1.1474 | 0.8137 | 1.0861 | 0.9591 | 0.8102 | 0.8918 |
| Tyrosine_C13-label-2 | 0.7287 | 1.1515 | 0.9977 | 1.0369 | 1.4016 | 0.8903 | 0.7416 | 0.9811 |
| UDP_C12 PARENT | 1.6664 | 1.8955 | 0.5925 | 0.6380 | 1.0298 | 0.9050 | 0.7923 | 0.4569 |
| UDP_C13-label-4 | NA | NA | 1.0000 | NA | NA | NA | NA | NA |
| UDP_C13-label-6 | NA | NA | 1.0000 | NA | NA | NA | NA | NA |
| UDP_C13-label-9 | 1.0000 | NA | NA | NA | NA | NA | NA | NA |
| UDP-N-acetylglucosamine_C12 PARENT | 0.7959 | 1.6323 | 0.9584 | 0.7066 | 1.1881 | 0.9678 | 0.5939 | 0.9555 |
| UDP-N-acetylglucosamine_C13-label-1 | 1.0652 | 0.8595 | 1.1144 | 0.9059 | 1.5680 | 0.9522 | 0.9277 | 0.8781 |
| UDP-N-acetylglucosamine_C13-label-10 | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| UDP-N-acetylglucosamine_C13-label-16 | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| UDP-N-acetylglucosamine_C13-label-2 | NA | NA | 0.1126 | NA | 1.4090 | 0.9696 | NA | 1.1302 |
| UDP-N-acetylglucosamine_C13-label-4 | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| UMP_C12 PARENT | 1.2006 | 1.4529 | 0.6807 | 0.5877 | 1.9788 | 0.6834 | 0.7088 | 0.6047 |
| UMP_C13-label-1 | 0.7475 | 0.8533 | 0.4810 | 0.5226 | 3.7612 | 0.4984 | 0.6536 | 0.5553 |
| UMP_C13-label-2 | NA | NA | NA | NA | 1.0000 | NA | NA | NA |
| Uracil_C12 PARENT | 0.8748 | 1.1175 | 1.2182 | 0.8752 | 0.8750 | 1.1553 | 1.0582 | 0.7718 |
| Uracil_C13-label-1 | 1.0852 | 1.2570 | 1.2536 | 0.7666 | 0.9165 | 1.2032 | 1.1587 | 0.3467 |
| Uridine_C12 PARENT | 1.1345 | 0.1226 | 0.0714 | 1.2457 | 2.0004 | 0.9507 | 1.0776 | 0.8464 |
| Uridine_C13-label-1 | 0.8588 | NA | 0.6494 | 0.9375 | 0.9820 | 1.4644 | 0.7917 | 1.1055 |
| Uridine_C13-label-2 | NA | NA | 1.0000 | NA | NA | NA | NA | NA |
| Uridine_C13-label-3 | 0.8935 | 0.2756 | 0.4082 | 1.1916 | 1.6969 | 0.4358 | 0.7531 | 1.3981 |
| Urocanate_C12 PARENT | 0.5785 | 2.1578 | 0.9168 | 1.3150 | 0.9238 | 0.8775 | 0.6748 | 0.4846 |
| Urocanate_C13-label-1 | 0.8724 | 1.9747 | 1.3731 | 1.2130 | 0.8348 | 0.7200 | 0.5466 | 0.5183 |
| Urocanate_C13-label-2 | NA | 1.0743 | 0.9354 | 0.7968 | NA | 0.9427 | 1.0924 | NA |
| UTP_C12 PARENT | 0.2103 | 2.0489 | 0.8714 | 0.8856 | 0.7036 | 1.1507 | 0.9424 | 0.8116 |
| UTP_C13-label-1 | NA | NA | NA | NA | NA | NA | NA | NA |
| UTP_C13-label-6 | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| Valine_C12 PARENT | 0.9327 | 0.9604 | 1.3494 | 0.8928 | 1.2508 | 0.7894 | 0.7176 | 1.0965 |
| Valine_C13-label-1 | 1.0653 | 1.2350 | 0.6778 | 0.8178 | 1.1172 | 1.0574 | 0.7991 | 1.1142 |
| XMP_C12 PARENT | 1.7007 | 1.4222 | 0.2156 | 0.1928 | 2.0494 | 0.4181 | 1.0742 | 0.1247 |
| XMP_C13-label-1 | 0.7470 | 0.4847 | NA | NA | 3.3736 | 0.6747 | 0.7411 | NA |
| XMP_C13-label-4 | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
Factors:
| F1 | Diet:Control | | Genotype:KP |
| F2 | Diet:Control | | Genotype:PGKP |
| F3 | Diet:Control | | Genotype:PolG |
| F4 | Diet:Control | | Genotype:wt |
| F5 | Diet:Ser/Gly free | | Genotype:KP |
| F6 | Diet:Ser/Gly free | | Genotype:PGKP |
| F7 | Diet:Ser/Gly free | | Genotype:PolG |
| F8 | Diet:Ser/Gly free | | Genotype:wt |
