Data for (Study ST004082)
(Analysis AN006759)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 |
|---|---|---|
| 1H-Imidazole-4-propionic acid | 0.8421 | 1.1579 |
| 1-Methyl-2-pyrrolidone | 0.8882 | 1.1677 |
| 1-Methyl-4-imidazoleacetic acid | 0.9672 | 1.0328 |
| 1-Methyladenosine | 1.0145 | 0.9855 |
| 1-Methylnicotinamide | 1.0000 | 1.0000 |
| "2,6-Diaminopimelic acid" | 1.0000 | NA |
| "2-Amino-2-(hydroxymethyl)-1,3-propanediol" | 1.0177 | 0.9823 |
| 2-Amino-2-methyl-1-propanol | 0.9935 | 1.0065 |
| 2-Aminoadipic acid" | 1.1410 | 0.8590 |
| 2-Aminobutyric acid | 0.9401 | 1.0599 |
| 2-Aminooctanoic acid | 0.9753 | 1.0370 |
| 2^-Deoxycytidine | 0.9128 | 1.0872 |
| 2^-Deoxyguanosine | 1.0515 | 0.9485 |
| 2^-Deoxyinosine | 0.8319 | 1.1681 |
| 2-Methylserine | 0.9510 | 1.0490 |
| 2-Methylthiazolidine-4-carboxylic acid | 0.5261 | 1.4739 |
| 2^-O-Methylcytidine | 0.9787 | 1.0213 |
| 3-(3,4-Dihydroxyphenyl)-2-methylalanine" | 0.9266 | 1.0734 |
| 3-Amino-2-piperidone | 0.9785 | 1.0215 |
| 3-Aminobutyric acid | NA | 1.0000 |
| 3-Aminoisobutyric acid | 1.0455 | 0.9545 |
| 3-Guanidinopropionic acid-1 | 1.1610 | 0.8390 |
| 3-Guanidinopropionic acid-2 | 1.0560 | 0.9440 |
| 3-Hydroxyisovalerylcarnitine | 1.0741 | 0.9259 |
| 3-Hydroxyproline | 1.0000 | 1.0000 |
| 3-Methylcytidine | 0.9620 | 1.0380 |
| 3-Methylguanine | 1.0000 | NA |
| 3-Methylhistidine" | 0.9348 | 1.0652 |
| 4-Acetamido-2-aminobutyric acid | 0.8328 | 1.1672 |
| 4-Guanidinobutyric acid | 0.8400 | 1.1600 |
| 4-Methyl-5-thiazoleethanol | 0.8152 | 1.5544 |
| 4-Oxopyrrolidine-2-carboxylic acid | 0.9449 | 1.0551 |
| "5-Amino-3,4-dihydro-2H-pyrrole-2-carboxylic acid" | 1.0000 | 1.0000 |
| 5-Amino-4-oxovaleric acid | 0.6249 | 1.3751 |
| 5-Aminovaleric acid | 1.1136 | 0.8864 |
| 5^-Deoxy-5^-methylthioadenosine | 1.0769 | 0.9231 |
| 5^-Deoxyadenosine" | 0.7291 | 1.2709 |
| 5-Hydroxylysine | 0.9083 | 1.0917 |
| 5-Methylcytidine | 0.8559 | 1.1441 |
| 6-Aminohexanoic acid | 1.0435 | 0.8696 |
| 7-Methylguanine | 0.8866 | 1.1134 |
| Acetylcholine | 1.0923 | 0.8616 |
| Acetylpyrazine | 1.0411 | 0.9589 |
| Adenine | 0.8095 | 1.1905 |
| Adenosine | 0.9474 | 1.0526 |
| ADMA | 0.8971 | 1.1029 |
| Agmatine | 1.0000 | NA |
| Ala | 0.9621 | 1.0379 |
| Ala-Ala | 0.9425 | 1.0575 |
| Ala-Hyp | 0.8780 | 1.1220 |
| Alliin | 0.8184 | 1.1816 |
| Aminoacetone | 0.9615 | 1.0385 |
| Anserine_divalent | 0.9899 | 1.0101 |
| Arabinosylhypoxanthine | NA | NA |
| Arg | 0.9733 | 1.0267 |
| Arg-Glu | 0.9401 | 1.0599 |
| Arginine ethyl ester | 1.0867 | 0.9133 |
| Argininic acid | 1.0452 | 0.9548 |
| Argininosuccinic acid | 0.9606 | 1.0394 |
| Asn | 0.9634 | 1.0366 |
| Asp | 1.0652 | 0.9348 |
| Azetidine 2-carboxylic acid | 1.3522 | 0.7652 |
| Benzylamine" | 1.0000 | 1.0000 |
| Betaine | 0.9134 | 1.0866 |
| Betaine aldehyde_+H2O | 1.3333 | 0.6667 |
| Butyrylcarnitine | 0.9677 | 1.0323 |
| Cadaverine-1" | 1.0000 | NA |
| Cadaverine-2" | 0.8218 | 1.1782 |
| Carboxymethyllysine | 0.9967 | 1.0033 |
| Carnitine | 1.0651 | 0.9349 |
| Carnosine | 1.0113 | 0.9887 |
| CDP-ethanolamine | 1.0851 | 0.9149 |
| Choline | 1.0137 | 0.9863 |
| cis-4-Hydroxyproline | 0.9397 | 1.0603 |
| Citrulline | 0.9244 | 1.0756 |
| Creatine | 0.9810 | 1.0190 |
| Creatinine | 1.1541 | 0.8459 |
| Crotonic acid betaine | 1.0182 | 0.9818 |
| Cyclohexylamine | 0.7903 | 1.2097 |
| Cys | 0.4434 | 1.5566 |
| Cys-Gly | 0.6466 | 1.3534 |
| Cystathionine | 0.9000 | 1.1000 |
| Cysteine glutathione disulfide | 0.5887 | 1.4113 |
| Cytidine | 0.9789 | 1.0211 |
| Cytosine | 0.9942 | 1.0058 |
| Diethanolamine | 0.9800 | 1.0200 |
| Diisopropanolamine | 1.0187 | 0.9813 |
| Dopamine" | 1.0098 | 0.9902 |
| Ectoine | 0.7373 | 1.2627 |
| Ethanolamine | 1.0949 | 0.9051 |
| Folic acid | 0.6112 | 1.3888 |
| GABA | 1.1870 | 0.8130 |
| Gln | 0.9634 | 1.0366 |
| Glu | 0.9536 | 1.0464 |
| Gluconolactone | 0.8939 | 1.1061 |
| Glucosamine | 1.0476 | 0.9524 |
| Glu-Glu | 0.9867 | 1.0133 |
| Glutarylcarnitine | 1.0245 | 0.9633 |
| Glutathione (GSH) | 0.9945 | 1.0055 |
| Glutathione (GSSG)_divalent | 0.9545 | 1.0455 |
| Gly | 0.9860 | 1.0140 |
| Gly-Asp | 0.9289 | 1.0711 |
| Glycerol | 0.8564 | 1.1436 |
| Glycerophosphocholine | 0.9309 | 1.0691 |
| Glycerophosphorylethanolamine | 0.9565 | 1.0435 |
| Glycylsarcosine | 1.0000 | 1.0000 |
| Gly-Gly | 0.9260 | 1.0740 |
| Gly-Gly-Gly | 0.9577 | 1.0423 |
| Gly-Hyp | 0.6866 | 1.3134 |
| Gly-Pro-Hyp | 0.7861 | 1.2139 |
| Guanidoacetic acid | 0.7820 | 1.2180 |
| Guanine | 0.9530 | 1.0470 |
| Guanosine | 0.9146 | 1.0854 |
| H-Asp(Gly-OH)-OH | 1.0405 | 0.9595 |
| H-Asp(Lys-OH)-OH" | 1.0761 | 0.9239 |
| Hercynine | 1.6931 | 0.3069 |
| Hexamine | 1.0000 | NA |
| His | 0.9261 | 1.0739 |
| His-Glu | 0.9007 | 1.0993 |
| Histamine | 1.2267 | 0.6599 |
| Homoarginine | 0.9070 | 1.0930 |
| Homocarnosine | 1.0307 | 0.9539 |
| Homocitrulline | 0.9000 | 1.1000 |
| Homocysteine | 0.5923 | 1.4077 |
| Homoserine | 0.9527 | 1.0473 |
| Homoserinelactone | 1.0543 | 0.9457 |
| Hydroxyproline | 0.8538 | 1.1462 |
| Hypotaurine | 1.0891 | 0.9109 |
| Hypoxanthine | 0.8739 | 1.1261 |
| Ile | 0.9451 | 1.0549 |
| Ile-Pro-Pro | 0.9474 | 1.0526 |
| Imidazole-4-acetic acid | 0.9275 | 1.0725 |
| Imidazole-4-methanol | 1.0000 | NA |
| Imidazolelactic acid | 0.9207 | 1.0793 |
| Inosine | 0.9255 | 1.0745 |
| Isobutylamine | NA | 1.0000 |
| Isonicotinamide" | 0.8063 | 1.1937 |
| Isopropanolamine | 1.1111 | 0.8889 |
| Isovalerylcarnitine | 1.0705 | 0.9295 |
| Kynurenine | 0.9167 | 1.0833 |
| Lauroylcarnitine | 1.1905 | 0.8095 |
| Leu | 0.9259 | 1.0741 |
| Leu-Leu-Tyr | 0.8750 | 1.1250 |
| Lidocaine | 1.0000 | NA |
| Lys | 0.9520 | 1.0480 |
| Mannosamine | 1.2341 | 0.6488 |
| Melamine | 1.2165 | 0.7835 |
| Met | 0.8756 | 1.1244 |
| Methionine sulfoxide | 1.0061 | 0.9939 |
| Methylguanidine | 0.5981 | 1.6029 |
| Morpholine | 0.7304 | 1.2696 |
| N1-Acetylspermidine | 0.9496 | 1.0504 |
| N-(1-Deoxy-1-fructosyl)glycine | 1.0464 | 0.9536 |
| N-(1-Deoxy-1-fructosyl)leucine | 1.1847 | 0.8153 |
| N-(1-Deoxy-1-fructosyl)threonine | 1.2853 | 0.7147 |
| N-(1-Deoxy-1-fructosyl)valine | 1.2727 | 0.7273 |
| N1-Methylguanosine | 1.0000 | 1.0000 |
| "N2,N2-Dimethylguanosine" | 0.9015 | 1.0985 |
| N6-Acetyllysine | 0.9375 | 1.0625 |
| N6-Methyllysine | 0.9731 | 1.0269 |
| "N6,N6-Dimethyllysine" | 0.9736 | 1.0264 |
| "N6,N6,N6-Trimethyllysine" | 0.9606 | 1.0394 |
| N8-Acetylspermidine | 0.7670 | 1.2330 |
| N-Acetylcarnosine | NA | 1.0000 |
| N-Acetylgalactosamine | 0.8310 | 1.1690 |
| N-Acetylglucosylamine | 0.9627 | 1.0373 |
| N-Acetylhistidine | 0.9890 | 1.0110 |
| N-Acetyllysine | 0.8979 | 1.1021 |
| N-Acetylornithine | 0.9535 | 1.0465 |
| N-Acetylserine | 1.0000 | 1.0000 |
| N’-Formylkynurenine | 1.2190 | 0.7810 |
| Nicotinamide-2 | 1.0143 | 0.9857 |
| Nicotine | NA | 1.0000 |
| Nicotinic acid | 1.9469 | 0.5265 |
| NMN | 0.9399 | 1.0601 |
| "N,N-Dimethylglycine" | 0.9111 | 1.0889 |
| Normetanephrine_-H2O | NA | 1.0000 |
| N-α-Acetylarginine | 1.0513 | 0.9487 |
| Nω-(Carboxymethyl)arginine | 1.0000 | 1.0000 |
| Nω-Methylarginine | 0.9344 | 1.0656 |
| O-Acetylcarnitine | 0.9244 | 1.0756 |
| O-Acetylhomoserine | 1.0297 | 0.9703 |
| Octanoylcarnitine | 1.0317 | 0.9524 |
| Ophthalmic acid | 1.0111 | 0.9889 |
| Ornithine | 0.9905 | 1.0095 |
| Penicillamine | 1.0155 | 0.9845 |
| Phe | 0.9375 | 1.0625 |
| Phosphorylcholine | 0.9729 | 1.0271 |
| Pipecolic acid | 0.9416 | 1.0584 |
| Piperidine | 1.0126 | 0.9874 |
| Pro | 0.9531 | 1.0469 |
| Pro-Hyp | 0.7413 | 1.2587 |
| Propionylcarnitine | 1.0894 | 0.9106 |
| Putrescine | 0.8879 | 1.1121 |
| Pyridoxal | 0.9231 | 1.0769 |
| Pyridoxamine | 1.1685 | 0.8315 |
| Pyridoxamine 5^-phosphate | 1.0935 | 0.9065 |
| Pyridoxine | 0.9149 | 1.0851 |
| Pyridoxol 5^-Phosphate | 0.8889 | 1.1111 |
| Pyroglutamine | 1.0566 | 0.9434 |
| Riboflavin | 1.1332 | 0.8668 |
| S-(2-Carboxyethyl)cysteine | 0.9162 | 1.0838 |
| Saccharopine | 1.1011 | 0.8989 |
| S-Adenosylhomocysteine | 1.1985 | 0.8015 |
| S-Adenosylmethionine | 0.8727 | 1.1273 |
| S-Allylcysteine | 0.9497 | 1.0754 |
| Sarcosine | 0.9919 | 1.0081 |
| S-Carboxymethylcysteine | 0.8872 | 1.1128 |
| SDMA | 0.9119 | 1.0881 |
| Ser | 1.0208 | 0.9792 |
| Ser-Glu | 0.9286 | 1.0714 |
| Serotonin | 1.0266 | 0.9734 |
| S-Lactoylglutathione | 1.3333 | 0.6667 |
| S-Methylcysteine | 0.8980 | 1.1020 |
| S-Methylglutathione | 1.2125 | 0.7875 |
| S-Methylmethionine | 0.7931 | 1.2069 |
| S-Nitrosoglutathione | 1.1030 | 0.8970 |
| Spermidine | 0.9603 | 1.0397 |
| Spermine | 0.9470 | 1.0530 |
| Stachydrine | 1.0462 | 0.9846 |
| Streptomycin sulfate_+H2O_divalent | 0.9668 | 1.0332 |
| Subaphylline | 0.8889 | 1.1111 |
| Succinyladenosine | 0.9322 | 1.0678 |
| Succinylcarnitine | 1.0110 | 0.9890 |
| Taurine | 1.1042 | 0.8958 |
| Thiamine | 0.9123 | 1.0877 |
| Thiamine phosphate | NA | NA |
| Thiaproline | 0.8986 | 1.1014 |
| Thr | 0.9381 | 1.0619 |
| Thr-Asp | 0.9065 | 1.0935 |
| Tiglylcarnitine | 0.9348 | 1.0652 |
| Tranexamic acid | 0.9513 | 1.1462 |
| trans-Glutaconic acid | 0.9439 | 1.0561 |
| Triethanolamine | 1.1409 | 0.8591 |
| Trigonelline | 0.7636 | 1.2364 |
| Trimethylamine N-oxide | 0.9264 | 1.0736 |
| Tropine | 0.4000 | 1.6000 |
| Trp | 0.9091 | 1.0909 |
| Tryptamine | 1.3895 | 0.4158 |
| Tyr | 0.9440 | 1.0560 |
| Tyramine | NA | 1.0000 |
| Tyr-Arg_divalent | 0.8217 | 1.1783 |
| Tyr-Glu | 0.8671 | 1.1329 |
| Tyrosine methyl ester | 1.1960 | 0.8040 |
| Urea | 0.7960 | 1.2040 |
| Urocanic acid | 0.9414 | 1.0586 |
| Val | 0.9320 | 1.0680 |
| Val-Pro-Pro | 1.1362 | 0.8638 |
| Xanthine | 0.8496 | 1.1504 |
| β-Ala | 1.0180 | 0.9820 |
| β-Ala-Lys | 0.9606 | 1.0394 |
| γ-Butyrobetaine | 0.9787 | 1.0213 |
| γ-Carboxyglutamic acid | 1.0192 | 0.9808 |
| γ-Glu-Ala | 1.0175 | 0.9825 |
| γ-Glu-Arg_divalent | 0.9430 | 1.0570 |
| γ-Glu-Asn | 1.0038 | 0.9962 |
| γ-Glu-Asp | 1.0571 | 0.9429 |
| γ-Glu-Cys | 1.0067 | 0.9933 |
| γ-Glu-Glu | 0.9011 | 1.0989 |
| γ-Glu-Gly | 1.0342 | 0.9658 |
| γ-Glu-His | 1.0137 | 0.9863 |
| γ-Glu-Leu" | 0.9536 | 1.0464 |
| γ-Glu-Lys_divalent | 0.8285 | 1.1715 |
| γ-Glu-Met | 0.7484 | 1.2516 |
| γ-Glu-Phe | 0.9698 | 1.0302 |
| γ-Glu-Ser | 1.0270 | 0.9730 |
| γ-Glu-Thr | 0.9545 | 1.0455 |
| γ-Glu-Trp | 0.9698 | 1.0302 |
| γ-Glu-Tyr | 0.8108 | 1.1892 |
| γ-Glu-Val | 0.9661 | 1.0339 |
| γ-Glu-Val-Gly | 1.0386 | 0.9614 |
Factors:
| F1 | Group:Mut | Sample source:IMR90 fibroblasts |
| F2 | Group:WT | Sample source:IMR90 fibroblasts |
