Data for (Study ST004096)
(Analysis AN006789)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1-linoleoylglycerophosphocholine | NA | 0.7592 | NA | 1.1343 | 2.0773 | 0.8471 | 0.7157 | 0.7248 | 0.4022 | NA | 0.9596 | 1.3548 |
| 1-oleoylglycerophosphocholine | 0.4479 | 1.2890 | 0.7700 | 1.6291 | 0.4596 | 1.2113 | 0.8382 | 1.1560 | 0.4767 | 1.1395 | 0.4318 | 1.9243 |
| 1-palmitoylglycerophosphocholine | 0.6601 | 1.0246 | 0.7704 | 1.6834 | 0.7481 | 0.8997 | 0.8683 | 1.1460 | 0.6540 | 1.2928 | 0.6060 | 1.8175 |
| 1-stearoylglycerophosphocholine | 0.8996 | 1.2963 | 1.3044 | 1.0368 | 0.5746 | 0.3949 | 1.1298 | 1.0370 | 0.6191 | 1.2329 | 0.5468 | 1.8156 |
| 2-aminoadipate | 1.1538 | 1.3804 | 0.7994 | 1.0581 | 0.9761 | 1.0159 | 1.0544 | 0.9214 | 0.9130 | 0.9756 | 0.8064 | 0.9455 |
| 2-arachidonoylglycerophosphocholine* | 0.8363 | 1.4594 | 0.7458 | 1.1930 | 0.7858 | 0.8676 | 0.9638 | 1.1788 | 0.7626 | 1.2708 | 0.5649 | 1.4224 |
| 2-arachidonoylglycerophosphoethanolamine* | 0.8093 | 1.0527 | 0.6980 | 1.0430 | 0.9967 | 0.9904 | 0.8055 | 1.2868 | 0.7589 | 1.0868 | 0.7889 | 1.6830 |
| 2-docosahexaenoylglycerophosphoethanolamine* | 1.0466 | 0.8868 | 0.9116 | 0.8040 | 1.0524 | 0.7398 | 1.1614 | 1.1207 | 1.0460 | 1.0998 | 0.8406 | 1.2902 |
| 2-docosapentaenoylglycerophosphoethanolamine* | 0.9395 | 1.3573 | 0.7265 | 1.0434 | 0.8818 | 0.7003 | 0.9412 | 1.2362 | 1.0176 | 0.9633 | 0.7264 | 1.3594 |
| 2-linoleoylglycerophosphocholine* | 0.8780 | 1.0222 | 0.8649 | 1.2200 | 0.9899 | 0.9676 | 1.0578 | 0.7979 | 1.1824 | 0.9408 | 0.6384 | 1.2071 |
| 2-methylbutyroylcarnitine | NA | 0.8498 | NA | 0.9050 | NA | 1.1994 | NA | 0.8682 | NA | 0.8601 | NA | 1.2238 |
| 2-oleoylglycerophosphocholine* | 0.6207 | 1.3178 | 0.9021 | 1.8735 | 0.6138 | 1.1514 | 0.8607 | 1.0095 | 0.7996 | 1.0513 | 0.5541 | 1.5066 |
| 2-oleoylglycerophosphoethanolamine* | 1.1872 | 0.7697 | 1.1893 | 1.1726 | 1.1388 | 0.5320 | 1.4903 | 0.8119 | 1.1221 | 0.9673 | 0.8928 | 0.6523 |
| 2-palmitoylglycerophosphocholine* | 0.8677 | 1.4317 | 0.5692 | 1.1984 | 0.9068 | 0.9923 | 1.0012 | 1.2178 | 0.8052 | 1.0610 | 0.6730 | 1.4297 |
| 2-palmitoylglycerophosphoethanolamine* | 1.0205 | 1.3432 | 1.1150 | 1.0893 | 1.0825 | 0.6723 | 0.9285 | 1.0243 | 0.8225 | 1.0074 | 0.6725 | 1.3590 |
| 2-stearoylglycerophosphocholine* | 0.8699 | 0.9181 | 1.2472 | 0.9533 | NA | NA | 1.1110 | 1.1780 | 0.5194 | 1.0441 | NA | 0.9099 |
| 3-dehydrocarnitine* | 0.4795 | 1.7629 | 0.2403 | 0.9274 | 0.4950 | 1.8523 | 0.4666 | 1.2386 | 0.3997 | 1.3137 | 0.4711 | 2.3528 |
| 3-ureidopropionate | 1.0295 | 1.0585 | 0.6290 | 1.1318 | 0.9020 | 1.0829 | 1.4087 | 1.1762 | 1.0832 | 1.1063 | 0.4513 | 0.6736 |
| 5-methylthioadenosine (MTA) | 0.5403 | 1.2087 | 0.3958 | 1.4841 | 0.6153 | 1.1836 | 0.9336 | 1.4918 | 0.7539 | 1.2008 | 0.8044 | 1.3878 |
| 5-oxoproline | 0.4776 | 1.5354 | 0.4054 | 1.6267 | 0.5980 | 1.9146 | 0.4962 | 1.0697 | 0.5080 | 1.0950 | 0.5140 | 1.7595 |
| acetylcarnitine | 0.2565 | 1.3925 | 0.2751 | 1.5519 | 0.4396 | 1.9284 | 0.2131 | 1.4457 | 0.1560 | 1.2491 | 0.4114 | 2.6808 |
| adenosine 5^-diphosphate (ADP) | 0.8417 | 1.6361 | 0.5442 | 1.5176 | 0.5155 | 1.6205 | 0.7984 | 1.0674 | 0.7233 | 0.6511 | 0.7306 | 1.2397 |
| adenosine 5^-monophosphate (AMP) | 1.5961 | 2.6068 | 0.5404 | 1.3326 | 0.3506 | 1.4106 | 0.4896 | 0.4972 | 0.6480 | 0.7433 | 0.6790 | 1.1057 |
| betaine | 0.4602 | 1.0501 | 0.6102 | 1.7915 | 0.4824 | 1.3218 | 0.6722 | 1.1756 | 0.4938 | 0.9661 | 0.8361 | 2.1401 |
| biopterin | 0.3305 | 1.4119 | NA | 1.2515 | 0.4331 | 1.5751 | 0.5285 | 0.8878 | NA | 0.9635 | 0.4278 | 1.3589 |
| butyrylcarnitine | NA | 0.7660 | NA | 0.9425 | NA | 1.5303 | NA | 0.6815 | NA | 0.5457 | NA | 1.5339 |
| carnitine | 0.0631 | 1.4505 | 0.1014 | 1.9131 | 0.1597 | 2.2998 | 0.1078 | 1.4067 | 0.0978 | 1.1714 | 0.2840 | 2.9447 |
| choline | 0.2003 | 1.8055 | 0.1661 | 1.3385 | 0.4065 | 2.5158 | 0.2881 | 1.2563 | 0.2116 | 1.4657 | 0.3625 | 1.9833 |
| cis-4-decenoyl carnitine | NA | 0.5850 | NA | 0.8202 | NA | 1.5023 | NA | 0.7477 | NA | 0.4524 | NA | 1.8924 |
| citrulline | 1.1511 | 1.1831 | 0.8719 | 0.9352 | 1.0581 | 0.8128 | 1.1093 | 0.9354 | 1.1493 | 1.0855 | 0.9690 | 0.7392 |
| creatine | 1.1470 | 1.0779 | 1.1643 | 1.0384 | 0.9722 | 0.7921 | 1.1877 | 0.8091 | 1.1140 | 0.9292 | 0.9964 | 0.7717 |
| creatinine | 0.8923 | 0.6961 | 0.9980 | 0.9129 | 1.1541 | 1.2220 | 0.8379 | 0.4361 | 1.1414 | 0.9758 | 1.0509 | 1.1678 |
| cytidine | NA | 1.1329 | NA | 0.9743 | NA | 0.8227 | NA | NA | NA | NA | NA | 1.0513 |
| cytidine 5^-monophosphate (5^-CMP) | NA | 0.6959 | NA | 0.8713 | NA | 1.0636 | NA | 0.8270 | NA | 0.7649 | NA | 1.5232 |
| decanoylcarnitine | 0.2667 | 1.2106 | 0.2553 | 1.3197 | 0.3720 | 1.8838 | 0.4705 | 1.5671 | 0.3691 | 1.2998 | 0.3959 | 2.5896 |
| deoxycarnitine | 0.1480 | 1.4569 | 0.0856 | 1.7293 | 0.3506 | 2.2764 | 0.1674 | 1.3845 | 0.1226 | 1.1211 | 0.3752 | 2.7826 |
| ergothioneine | 0.2010 | 0.9114 | 0.2156 | 1.3477 | 0.4055 | 1.1509 | 0.7533 | 1.6180 | 0.5449 | 1.7405 | 0.9380 | 2.1732 |
| erythro-sphingosine-1-phosphate | 1.1877 | 1.1571 | 1.0983 | 1.1931 | 1.1976 | 0.4577 | 1.1338 | 0.6927 | 1.3604 | 0.7767 | 0.8401 | 0.7725 |
| gamma-glutamylcysteine | 0.7450 | 1.5303 | 0.9545 | 1.2073 | 0.5280 | 1.6758 | 0.5585 | 0.6501 | 1.0142 | 0.8362 | 0.6911 | 0.9818 |
| gamma-glutamylglutamate | NA | 1.0830 | NA | 0.8651 | NA | 0.9063 | NA | 1.1634 | NA | 0.9195 | NA | 1.0498 |
| gamma-glutamylisoleucine* | 1.1894 | 1.0714 | 0.7789 | 1.0572 | 1.0675 | 0.9223 | 1.1065 | 1.1396 | 0.9695 | 0.9635 | 0.8781 | 0.9155 |
| gamma-glutamylleucine | 0.9402 | 1.3753 | 0.5274 | 1.2954 | 0.8197 | 1.3511 | 0.8028 | 1.0946 | 0.7634 | 1.0110 | 0.5330 | 1.4860 |
| gamma-glutamylthreonine* | 1.1904 | 1.1871 | 0.7464 | 0.8361 | 1.1486 | 0.6970 | 1.2844 | 0.7766 | 1.4383 | 0.8533 | 1.1511 | 0.5877 |
| gamma-glutamylvaline | 1.3979 | 1.1868 | 0.8510 | 0.9821 | 1.0804 | 0.5995 | 1.4230 | 0.8025 | 1.4225 | 0.9234 | 0.9155 | 0.4154 |
| GDP-glucose | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.7324 | 1.2676 |
| GDP-mannose | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.7726 | 1.2274 |
| glutamate | 0.5611 | 1.4211 | 0.5523 | 1.3894 | 0.7968 | 1.2971 | 0.8858 | 1.0177 | 0.7721 | 1.0832 | 0.9057 | 1.3178 |
| glutamate, gamma-methyl ester | 0.6001 | 1.2117 | 0.7745 | 1.8448 | 0.6109 | 1.4188 | 0.5523 | 0.6379 | 1.2003 | 0.9773 | 0.6129 | 1.3584 |
| glutamine | 1.0771 | 1.0089 | 0.8362 | 0.9695 | 1.4739 | 0.4267 | 1.2787 | 0.5877 | 1.0764 | 0.9869 | 1.5810 | 0.6970 |
| glutathione, oxidized (GSSG) | 1.0277 | 1.1802 | 0.9193 | 1.1543 | 0.9318 | 1.2160 | 1.0796 | 0.9514 | 0.9592 | 0.8985 | 0.7629 | 0.9192 |
| glutathione, reduced (GSH) | 0.7522 | 1.0911 | 0.8227 | 1.5083 | 0.7552 | 1.4581 | 0.8736 | 0.9153 | 0.9392 | 0.8687 | 0.7116 | 1.3039 |
| glycerophosphorylcholine (GPC) | 1.4817 | 0.2137 | 1.7823 | 0.4081 | 1.0276 | 0.0704 | 2.2932 | 0.2220 | 2.2574 | 0.4599 | 1.2642 | 0.0391 |
| guanosine 5^- monophosphate (5^-GMP) | 2.6275 | 2.3493 | 0.7297 | 0.7792 | 0.5315 | 0.7115 | 0.4307 | 0.3592 | 0.7015 | 0.5363 | 0.5774 | 0.5826 |
| heme* | 0.7155 | 0.7333 | 0.9234 | 0.6227 | 1.2269 | 1.2149 | 1.3033 | 1.3920 | 0.7656 | 0.6570 | 1.0098 | 1.4358 |
| hexanoylcarnitine | NA | 0.5610 | NA | 0.7709 | NA | 2.0379 | NA | 0.5022 | NA | 0.4156 | NA | 1.7124 |
| homostachydrine* | 0.6323 | 0.6931 | 0.8048 | 3.3703 | 0.5553 | 0.8043 | 0.6861 | 0.5672 | NA | 0.5318 | 0.6147 | 1.1132 |
| hydroxyisovaleroyl carnitine | NA | 0.9325 | NA | 1.2281 | 0.3610 | 1.4698 | 0.3280 | 1.0833 | NA | 0.8730 | 0.3559 | 1.9214 |
| inosine 5^-monophosphate (IMP) | 1.0085 | 1.7552 | 1.0484 | 1.0272 | 1.5020 | 0.5869 | 0.6412 | 0.4396 | 1.5266 | 0.6620 | 0.9431 | 0.8594 |
| isoleucine | 0.4124 | 1.8519 | 0.3871 | 1.6468 | 0.3353 | 2.3614 | 0.3349 | 0.9039 | 0.2543 | 0.7526 | 0.3332 | 2.2601 |
| isovalerylcarnitine | NA | 0.9092 | NA | 0.9810 | NA | 1.1569 | NA | 0.8916 | NA | 0.8137 | NA | 1.0111 |
| laurylcarnitine | 0.6519 | 0.7496 | 0.6485 | 1.3773 | 0.8860 | 1.1956 | 0.8381 | 1.1628 | 0.7927 | 1.0965 | 0.6103 | 1.9562 |
| leucine | 0.7709 | 1.5485 | 0.7150 | 1.4996 | 0.6048 | 1.7809 | 0.5988 | 0.8591 | 0.5244 | 0.7937 | 0.5755 | 1.7288 |
| lysine | 0.6889 | 1.4247 | 0.4394 | 1.5239 | 0.8218 | 1.9379 | 0.6051 | 0.8206 | 0.6288 | 1.1529 | 0.5842 | 1.3718 |
| malonylcarnitine | 0.3865 | 1.2185 | 0.4034 | 1.4467 | 0.6065 | 1.8806 | 0.3748 | 0.8147 | NA | 0.7666 | 0.3631 | 1.8081 |
| N-6-trimethyllysine | 0.9811 | 1.3020 | 0.7565 | 1.2206 | 1.0768 | 1.1655 | 0.7534 | 1.0626 | 0.6755 | 1.0786 | 0.7599 | 1.1676 |
| N-acetylneuraminate | 0.5816 | 1.6102 | 0.4161 | 1.1612 | 0.6806 | 1.8416 | 0.4049 | 1.1098 | 0.2013 | 0.9143 | 0.4162 | 2.5161 |
| N-acetylornithine | 0.8791 | 0.8567 | 1.0336 | 1.0436 | 1.0886 | 0.9836 | 1.4035 | 0.8505 | 1.0196 | 0.7665 | 1.0343 | 1.0403 |
| N-carbamoylaspartate | NA | 0.6251 | NA | 0.7250 | NA | 0.8042 | NA | NA | NA | NA | NA | 1.3291 |
| nicotinamide | 0.1585 | 2.6252 | 0.1096 | 1.7452 | 0.2591 | 2.8770 | 0.0843 | 0.9799 | 0.0668 | 0.7371 | 0.2770 | 2.0806 |
| nicotinamide adenine dinucleotide (NAD+) | 1.9015 | 0.4379 | 1.6565 | 0.7664 | 1.3368 | 0.4456 | 1.5210 | 0.5391 | 1.2143 | 0.5316 | 0.9953 | 0.6539 |
| nicotinamide adenine dinucleotide phosphate (NADP+) | 0.9796 | 0.7263 | 0.7928 | 1.1063 | 1.0005 | 0.7675 | 1.7464 | 1.1451 | 1.0254 | 0.8587 | 1.0443 | 0.8467 |
| nicotinamide ribonucleotide (NMN) | 1.9581 | 0.8680 | 1.9546 | 0.7439 | 1.3575 | 0.6088 | 1.1564 | 0.4349 | 1.0095 | 0.5252 | 0.8445 | 0.5384 |
| nicotinate ribonucleoside* | 1.2233 | 1.0089 | 0.7442 | 0.9423 | 0.8491 | NA | NA | NA | NA | NA | NA | NA |
| nicotinic acid mononucleotide (NaMN) | 2.3438 | 0.8688 | 1.2320 | 0.5619 | 1.7979 | 0.2188 | 0.9824 | 0.6337 | 0.7034 | 0.5312 | 0.7390 | 0.4193 |
| norophthalmate* | 0.9848 | NA | 0.7012 | NA | 0.4738 | NA | 1.6895 | NA | 1.7375 | 0.1407 | 1.0577 | NA |
| octanoylcarnitine | 0.0714 | 1.3496 | 0.0824 | 2.0297 | 0.1636 | 2.2712 | 0.1511 | 1.4689 | 0.1457 | 1.3940 | 0.2011 | 2.6715 |
| oleoylcarnitine | 0.5118 | 1.3107 | 0.5149 | 1.4744 | 0.6828 | 1.3686 | 0.7121 | 1.4481 | 0.5292 | 1.0673 | 0.5202 | 2.1484 |
| ophthalmate | 1.8214 | 0.1680 | 1.1550 | 0.1196 | 1.1020 | NA | 1.6562 | 0.1362 | 2.2400 | 0.2753 | 1.3263 | NA |
| palmitoylcarnitine | 0.6724 | 0.9320 | 0.5788 | 1.2990 | 0.7559 | 1.0855 | 0.8842 | 1.5419 | 0.5882 | 1.1271 | 0.6118 | 1.9981 |
| pantothenate | 0.8237 | 1.3681 | 0.2537 | 0.8071 | 0.8270 | 1.6043 | 0.7419 | 1.1769 | 0.5429 | 1.0837 | 0.6194 | 2.1515 |
| phenylalanine | 0.5547 | 1.6348 | 0.5128 | 1.7490 | 0.4914 | 2.0908 | 0.3882 | 0.8692 | 0.3159 | 0.7813 | 0.4670 | 2.1449 |
| pipecolate | 0.7867 | 0.8556 | 1.2327 | 1.8482 | 0.9352 | 1.2524 | 0.6859 | 0.7145 | 1.1219 | 1.2178 | 0.6125 | 0.6653 |
| proline | 0.5566 | 0.9500 | 0.7193 | 1.7136 | 0.7276 | 1.5528 | 0.8152 | 0.7911 | 0.7227 | 1.0134 | 0.8910 | 1.5466 |
| propionylcarnitine | 0.0773 | 1.5716 | 0.1146 | 1.5966 | 0.1373 | 2.2821 | 0.1328 | 1.4194 | 0.0611 | 1.1091 | 0.1429 | 2.9170 |
| serotonin (5HT) | 0.3134 | 1.5716 | 0.4863 | 0.4477 | 0.3342 | 1.9388 | 0.3763 | 0.7884 | 0.3205 | NA | 0.3515 | 1.4197 |
| S-methylglutathione | 0.4969 | 1.1880 | 0.6381 | 1.6809 | 0.7135 | 1.5137 | 0.7798 | 1.1376 | 0.7408 | 1.0058 | 0.7277 | 1.3772 |
| spermidine | 0.0634 | 1.3610 | 0.0679 | 1.6780 | 0.1680 | 2.5377 | 0.1431 | 1.7116 | 0.1073 | 1.2058 | 0.2381 | 2.7181 |
| sphinganine | 1.3781 | 1.3617 | 0.7648 | 1.2616 | 1.2224 | 0.9540 | 0.9775 | 0.9000 | 0.7457 | 0.8163 | 0.7203 | 0.9515 |
| sphingosine | 0.9704 | 1.5823 | 0.6492 | 1.4451 | 1.1220 | 0.9379 | 0.7362 | 0.9574 | 0.5969 | 0.7896 | 0.7331 | 1.5912 |
| stachydrine | 0.7685 | 1.1987 | 0.7294 | 3.6792 | 0.6156 | 1.1563 | 0.5664 | 0.5523 | 0.5412 | 0.6332 | 0.5248 | 1.0344 |
| stearoylcarnitine | 0.7798 | 1.0556 | 0.4184 | 0.9052 | 0.8513 | 1.0343 | 0.8520 | 1.4493 | 0.6190 | 0.9971 | 0.7898 | 2.1833 |
| succinylcarnitine | 0.7337 | 1.1849 | 0.5466 | 1.0247 | 0.7808 | 1.1695 | 0.8550 | 1.3223 | 0.7184 | 1.3067 | 0.8154 | 1.5419 |
| taurine | 0.5869 | 1.8016 | 0.6007 | 1.3481 | 0.6090 | 1.2750 | 0.7137 | 1.1539 | 0.6818 | 1.0572 | 0.7379 | 1.4341 |
| threonine | 0.4817 | 0.9356 | 0.7916 | 1.6985 | 0.9507 | 0.8950 | 0.7816 | 0.7713 | 0.9679 | 1.2351 | 1.2933 | 1.1977 |
| trans-4-hydroxyproline | 0.7957 | 1.0087 | 1.1365 | 1.2276 | 0.9909 | 0.8008 | 0.9784 | 0.7584 | 0.9765 | 0.9363 | 1.4237 | 0.9664 |
| trigonelline (N^-methylnicotinate) | 1.2177 | 1.3390 | 0.7813 | 0.9998 | 1.1356 | 0.9840 | 1.1393 | 0.7632 | 1.0689 | 0.9098 | 0.8846 | 0.7768 |
| tryptophan | 0.6026 | 1.7358 | 0.4846 | 1.5849 | 0.4249 | 2.0504 | 0.5370 | 1.0640 | 0.3283 | 0.8473 | 0.4548 | 1.8853 |
| tyrosine | 0.3714 | 1.5879 | 0.4209 | 1.6056 | 0.3222 | 2.2214 | 0.3241 | 0.7488 | 0.2838 | 0.7384 | 0.3788 | 2.1429 |
| valine | 0.6660 | 1.8465 | 0.3721 | 1.7853 | 0.3050 | 2.3231 | 0.2800 | 0.7832 | 0.3016 | 0.5877 | 0.2772 | 1.9486 |
| xanthine | 0.6355 | 1.3820 | 0.5745 | 1.3753 | 1.0469 | 1.0894 | 0.8839 | 1.0324 | 0.8588 | 1.0592 | 0.6601 | 0.9956 |
Factors:
| F1 | Sample source:RBC | GENOTYPE:PRDX2 | GROUP_DESC:Biotin + | DAY:15 |
| F2 | Sample source:RBC | GENOTYPE:PRDX2 | GROUP_DESC:Biotin - | DAY:15 |
| F3 | Sample source:RBC | GENOTYPE:PRDX2 | GROUP_DESC:Biotin + | DAY:20 |
| F4 | Sample source:RBC | GENOTYPE:PRDX2 | GROUP_DESC:Biotin - | DAY:20 |
| F5 | Sample source:RBC | GENOTYPE:PRDX2 | GROUP_DESC:Biotin + | DAY:8 |
| F6 | Sample source:RBC | GENOTYPE:PRDX2 | GROUP_DESC:Biotin - | DAY:8 |
| F7 | Sample source:RBC | GENOTYPE:WT | GROUP_DESC:Biotin + | DAY:15 |
| F8 | Sample source:RBC | GENOTYPE:WT | GROUP_DESC:Biotin - | DAY:15 |
| F9 | Sample source:RBC | GENOTYPE:WT | GROUP_DESC:Biotin + | DAY:20 |
| F10 | Sample source:RBC | GENOTYPE:WT | GROUP_DESC:Biotin - | DAY:20 |
| F11 | Sample source:RBC | GENOTYPE:WT | GROUP_DESC:Biotin + | DAY:8 |
| F12 | Sample source:RBC | GENOTYPE:WT | GROUP_DESC:Biotin - | DAY:8 |
