Data for (Study ST004297)

(Analysis AN007144)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Metabolite	F1	F2
1-methyl-4-imidazoleacetate	1.0012	0.9985
1-methyl-5-imidazoleacetate	1.1422	0.8261
1-methylguanidine	1.1511	0.8474
1-methylnicotinamide	0.9885	1.0142
1-methylurate	1.0370	0.9523
1-ribosyl-imidazoleacetate*	1.0540	0.9335
2-amino-4-cyanobutanoate	0.9984	1.0020
2-aminoheptanoate	0.9987	1.0016
(2-butoxyethoxy)acetic acid	1.0886	0.8621
2-furoylcarnitine	1.0470	0.9312
2-hydroxyglutarate	1.1251	0.8460
2-methylbutyrylcarnitine (C5)	1.0370	0.9570
2-methylmalonylcarnitine (C4-DC)	1.0255	0.9673
2-methylserine	1.0468	0.9420
2^-O-methylcytidine	1.0079	0.9903
2-oxoarginine*	1.0202	0.9751
2-piperidinone	1.3901	0.5056
2-pyrrolidinone	1.1307	0.8391
3-amino-2-piperidone	0.9275	1.0892
3-aminoisobutyrate	0.9913	1.0107
3-(cystein-S-yl)acetaminophen*	0.8634	1.1905
3-formylindole	1.0387	0.9524
3-hydroxybutyroylglycine**	1.0032	0.9961
3-hydroxyhexanoylcarnitine (1)	1.1744	0.7853
3-hydroxyindolin-2-one	1.2698	0.6391
3-hydroxykynurenine	1.0802	0.9077
3-hydroxyoctanoylcarnitine (1)	1.0706	0.9131
3-hydroxyoctanoylcarnitine (2)	1.0970	0.8806
3-hydroxyquinine	1.3167	0.6833
3-hydroxystachydrine*	1.2163	0.7286
3-methoxytyrosine	1.0833	0.8975
3-methylcrotonylglycine	1.0078	0.9922
3-methylcytidine	1.0738	0.9082
3-methylglutarylcarnitine (2)	1.0659	0.9187
3-phosphoglycerate	0.9430	1.0701
4-acetamidobutanoate	1.0869	0.8931
4-guanidinobutanoate	1.1318	0.8418
4-hydroxyglutamate	0.8349	1.1981
4-hydroxyphenylacetoylcarnitine	1.0384	0.9500
4-imidazoleacetate	1.2665	0.7837
5-(galactosylhydroxy)-lysine	0.9758	1.0297
5-hydroxylysine	0.9052	1.1166
5-hydroxyvalproate	0.9882	1.0118
5-methylthioadenosine (MTA)	0.9053	1.1165
5-methylthioribose**	0.9877	1.0150
6-aminocaproate	1.2676	0.4647
7-methylurate	1.1347	0.8346
7-methylxanthine	1.2839	0.5534
abacavir	0.6862	1.4708
acetoacetate	1.0836	0.8996
acetylcarnitine (C2)	1.1372	0.8312
adenine	0.9007	1.1241
adenosine 5^-monophosphate (AMP)	0.8266	1.2134
adipoylcarnitine (C6-DC)	1.0738	0.9092
alanine	1.0409	0.9497
alliin	1.1821	0.4234
alpha-hydroxymetoprolol	1.5607	0.4940
anthranilate	1.0198	0.9770
argininate*	1.0979	0.8794
arginine	0.8796	1.1482
asparagine	0.9868	1.0162
aspartate	0.8514	1.1829
atenolol	1.3962	0.5048
baclofen	0.7277	1.2723
benzoylcarnitine*	0.3523	1.8117
benzoylecgonine	1.5401	0.0548
beta-alanine	1.0130	0.9841
beta-guanidinopropanoate	1.0802	0.8920
beta-hydroxyisovaleroylcarnitine	1.0932	0.8853
betaine	1.0527	0.9351
butyrylcarnitine (C4)	1.1849	0.7853
caffeine	1.2354	0.5896
carboxyethyl-GABA	1.0315	0.9611
carnitine	1.0569	0.9300
cefazolin	0.5301	1.5126
ceftazidime	1.0000	NA
choline	0.9400	1.0739
choline phosphate	1.0247	0.9696
cis-urocanate	0.6771	1.3534
citramalate	1.1236	0.8110
citrulline	0.9828	1.0212
cotinine	1.2708	0.6528
creatine	0.9458	1.0668
creatinine	1.0421	0.9481
cyclo(gly-pro)	0.4356	1.6961
cyclo(leu-pro)	0.7853	1.2554
cyclo(met-pro)	0.7216	1.3276
cyclo(pro-val)	1.0008	0.9990
cys-gly, oxidized	1.2269	0.7223
cystathionine	0.9206	1.0977
cysteine	1.1871	0.7697
cysteine s-sulfate	0.9400	1.0750
cysteine sulfinic acid	1.0829	0.9032
cysteinylglycine	1.1113	0.8630
cysteinylglycine disulfide*	1.1170	0.8559
cystine	1.0901	0.8897
cytidine 5^-monophosphate (5^-CMP)	1.2848	0.6591
cytosine	1.1408	0.8122
deoxycarnitine	1.0481	0.9409
dexpanthenol	0.8559	1.2126
dimethylarginine (SDMA + ADMA)	1.0233	0.9713
dimethylglycine	1.0342	0.9579
dimethylguanidino valeric acid (DMGV)*	1.1439	0.8153
dimethyl sulfone	1.2422	0.6892
doxylamine	1.0841	0.7055
ectoine	1.0934	0.8748
emtricitabine	0.9249	1.2253
ergothioneine	1.1552	0.8081
ethyl alpha-glucopyranoside	1.1209	0.8168
formiminoglutamate	0.9916	1.0103
fosfomycin	1.5045	0.4955
fructosyllysine	0.9006	1.1224
gamma-carboxyglutamate	1.0080	0.9902
gamma-glutamyl-2-aminobutyrate	1.1287	0.8139
gamma-glutamylalanine	1.0412	0.9020
gamma-glutamyl-alpha-lysine	0.9677	1.0397
gamma-glutamylcitrulline*	1.2242	0.7233
gamma-glutamylglutamate	1.1371	0.8333
gamma-glutamylglutamine	1.2074	0.7447
gamma-glutamylglycine	1.0065	0.9920
gamma-glutamylhistidine	1.0339	0.9583
gamma-glutamylisoleucine*	0.8557	1.1776
gamma-glutamylleucine	0.9536	1.0571
gamma-glutamylmethionine	1.0504	0.9380
gamma-glutamylphenylalanine	1.0285	0.9649
gamma-glutamylthreonine	0.8968	1.1270
gamma-glutamyltryptophan	1.0131	0.9848
gamma-glutamylvaline	0.9620	1.0468
glutamate	0.9062	1.1154
glutamate, gamma-methyl ester	0.9773	1.0276
glutamine	1.0285	0.9649
glutarylcarnitine (C5-DC)	0.9825	1.0217
glycerol 3-phosphate	1.2585	0.6324
glycerophosphoethanolamine	0.9292	1.0872
glycerophosphorylcholine (GPC)	0.8763	1.1523
glycine	0.9818	1.0224
glycylproline	1.4380	0.4537
glycylvaline	1.0711	0.9017
guanidinoacetate	1.0263	0.9659
HEPES	1.0000	NA
hexanoylcarnitine (C6)	1.1377	0.8305
histidine betaine (hercynine)*	1.0324	0.9595
homoarginine	1.0112	0.9860
homostachydrine*	1.1855	0.7717
hydroxyasparagine**	1.0315	0.9612
hydroxybupropion	0.9265	1.0965
hydroxycotinine	1.1788	0.7507
hydroxy-N6,N6,N6-trimethyllysine*	0.9462	1.0664
hypotaurine	1.0176	0.9714
imidazole lactate	0.9538	1.0573
imidazole propionate	0.7997	1.2465
iminodiacetate (IDA)	0.9886	1.0140
indoleacetoylcarnitine*	0.9833	1.0255
indolelactate	1.0449	0.9448
indolin-2-one	1.0984	0.8377
inosine 5^-monophosphate (IMP)	0.8020	1.2453
isobutyrylcarnitine (C4)	1.1876	0.7658
isoleucine	0.9144	1.1054
isoleucylhydroxyproline*	0.9380	1.0764
isovalerylcarnitine (C5)	1.1054	0.8692
kynurenine	1.0002	0.9998
lamivudine	0.4866	2.5403
lamotrigine	0.8416	1.2375
lanthionine	0.9506	1.0620
leucine	0.9444	1.0685
leucylalanine	1.0325	0.9570
leucylglycine	0.9211	1.1098
leucylhydroxyproline*	1.0638	0.9200
levulinoylcarnitine	1.2012	0.7207
lidocaine	1.4909	0.3572
lysine	0.9602	1.0489
metformin	1.2256	0.7080
methionine	0.9466	1.0667
methionine sulfone	0.9548	1.0557
methionine sulfoxide	0.9691	1.0380
methyl indole-3-acetate	0.9596	1.0483
methylsuccinoylcarnitine	0.9900	1.0121
metoclopramide	0.8591	1.3170
metoprolol	1.0157	0.9799
metoprolol acid metabolite*	1.4562	0.5956
mirtazapine	1.2218	0.6894
N1-methyladenosine	0.9896	1.0128
N1-methylinosine	0.9782	1.0268
N1,N12-diacetylspermine	1.0851	0.8918
(N(1) + N(8))-acetylspermidine	1.1014	0.8752
N2-acetyl,N6-methyllysine	1.0464	0.9369
N2-acetyl,N6,N6-dimethyllysine	1.1129	0.8597
N2,N2-dimethylguanosine	0.9596	1.0497
N6-carboxymethyllysine	1.1782	0.8591
N6-methyladenosine	1.0838	0.9051
N6-methyllysine	1.0751	0.9076
N6,N6-dimethyllysine	1.0479	0.9410
N6,N6,N6-trimethyllysine	0.9007	1.1223
N-acetyl-1-methylhistidine*	1.0110	0.9856
N-acetyl-2-aminoadipate	0.9676	1.0392
N-acetylalliin	1.1319	0.6130
N-acetylarginine	0.9839	1.0199
N-acetyl-aspartyl-glutamate (NAAG)	0.9534	1.0577
N-acetylglucosamine/N-acetylgalactosamine	1.0354	0.9565
N-acetylglucosaminylasparagine	1.1900	0.7661
N-acetylglycine	1.0294	0.9638
N-acetylhistidine	1.0797	0.8947
N-acetyl-isoputreanine	1.0139	0.9829
N-acetylproline	1.0614	0.9243
N-acetylputrescine	1.0920	0.8867
N-acetyltheanine	1.0344	0.9578
N-alpha-acetylornithine	1.0767	0.9136
N-carbamoylalanine	1.1633	0.8196
N-ethylglycinexylidide	1.0982	0.8188
nicotinamide	1.0332	0.9575
nicotinamide riboside	0.9656	1.0426
N-methyl-GABA	0.9656	1.0492
N-methylhydroxyproline**	0.9742	1.0377
N-methylpipecolate	1.0844	0.8962
N-methylproline	1.2622	0.6772
N,N-dimethyl-5-aminovalerate	0.9660	1.0437
N,N-dimethylalanine	1.0570	0.9281
N,N-dimethyl-pro-pro	1.1094	0.8653
N,N,N-trimethyl-5-aminovalerate	1.1228	0.8488
N,N,N-trimethyl-alanylproline betaine (TMAP)	1.1245	0.8468
norcotinine	1.1974	0.6491
norfentanyl	1.4920	0.7751
O-desmethyltramadol	1.4089	0.4548
O-desmethyltramadol glucuronide	1.1838	0.7327
O-desmethylvenlafaxine	0.8563	1.1677
ondansetron	1.3054	0.5342
ornithine	0.9087	1.1124
oxindolylalanine	0.8815	1.1458
oxycodone	1.4093	0.7575
phentermine	1.0000	NA
phenylacetylcarnitine	1.1756	0.7685
phenylacetylglutamine	1.0604	0.9256
phenylalanine	1.0306	0.9624
phenylephrine	1.1164	0.7673
phosphate	1.0600	0.9262
phosphoethanolamine	1.0830	0.8978
picolinate	1.0302	0.9661
pimeloylcarnitine/3-methyladipoylcarnitine (C7-DC)	1.0697	0.9136
pipecolate	1.0578	0.9288
pro-hydroxy-pro	0.8740	1.1551
proline	0.9870	1.0160
prolylglycine	0.9710	1.0349
propionylcarnitine (C3)	1.1067	0.8686
pyridoxal	0.9911	1.0111
quinine	1.0572	0.7713
(R)-3-hydroxybutyrylcarnitine	1.2345	0.6968
ranitidine	1.1301	0.8792
ranitidine N-oxide*	0.5839	1.3269
ritalinic acid	0.5896	1.8208
rocuronium	1.4927	0.3700
S-1-pyrroline-5-carboxylate	0.9806	1.0221
(S)-3-hydroxybutyrylcarnitine	1.2047	0.7481
(S)-a-amino-omega-caprolactam	0.9933	1.0081
sarcosine	1.0049	0.9939
S-carboxyethylcysteine	0.2849	1.8801
S-carboxymethyl-cysteine	0.9079	1.1093
serine	0.9079	1.1133
serotonin	1.1026	0.8794
S-methylcysteine sulfoxide	1.1991	0.7549
S-methylmethionine	1.0473	0.8110
spermidine	1.1514	0.8122
stachydrine	1.1698	0.7910
suberoylcarnitine (C8-DC)	1.0444	0.9453
succinylcarnitine (C4-DC)	0.9886	1.0140
theanine	0.9557	1.1207
theobromine	1.3062	0.5547
thiamin (vitamin B1)	1.2412	0.7674
thioproline	1.0881	0.8915
threonine	0.9055	1.1163
tigloylglycine	0.9679	1.0359
tiglylcarnitine (C5:1-DC)	1.0474	0.9417
tramadol	1.4808	0.3443
trans-4-hydroxyproline	0.9176	1.1014
trans-urocanate	0.6229	1.4595
trazodone	1.1833	0.7404
triamterene	0.8545	1.2182
trigonelline (N^-methylnicotinate)	1.4935	0.4002
trimethylamine N-oxide	1.1941	0.7611
trizma acetate	1.3901	0.4562
tryptophan	0.9502	1.0613
tryptophan betaine	1.1311	0.8367
tyrosine	0.9645	1.0434
urea	1.0107	0.9869
valine	0.9495	1.0611
valylglycine	1.0011	0.9988
valylleucine	1.3304	0.6260
X-11787	1.0217	0.9732
X-11795	1.0775	0.9023
X-12096	1.0969	0.8807
X-12100	1.0074	0.9909
X-12101	1.0554	0.9318
X-12112	1.1283	0.8421
X-12117	1.1082	0.8668
X-12127	1.2099	0.7427
X-12199	1.0424	0.9532
X-12283	1.0164	0.9758
X-12462	0.9738	1.0322
X-12680	0.9300	1.0841
X-12689	0.9532	1.0576
X-12798	1.1250	0.8467
X-13507	0.9801	1.0243
X-13684	1.3060	0.5726
X-14056	1.3501	0.5691
X-15161	0.9853	1.0182
X-15461	1.0939	0.8892
X-16397	1.0584	0.9281
X-16580	1.0608	0.9252
X-17301	1.1721	0.6803
X-17304	0.6817	1.2305
X-17306	1.0000	NA
X-17323	1.1145	0.8255
X-17325	0.9495	1.0612
X-17346	1.0567	0.9310
X-21283	0.9597	1.0500
X-22162	1.0607	0.9253
X-23581	1.0623	0.9309
X-23583	1.1830	0.7621
X-23587	1.0632	0.9139
X-23593	0.9590	1.0504
X-23636	1.0011	0.9987
X-23639	1.2283	0.7208
X-23644	1.3435	0.5726
X-23648	0.7555	1.2976
X-23654	1.0946	0.8835
X-23655	1.2520	0.6297
X-23657	1.1000	0.8758
X-23659	1.0337	0.9579
X-23662	1.0223	0.9666
X-23665	0.9766	1.0290
X-23666	1.0252	0.9688
X-23739	0.8625	1.1692
X-23780	1.1672	0.7511
X-23997	1.0127	0.9838
X-24243	1.0270	0.9675
X-24408	1.0207	0.9762
X-24410	1.1273	0.8212
X-24411	1.2086	0.6652
X-24422	1.0724	0.9104
X-24425	0.8459	1.0493
X-24456	0.9559	1.0529
X-24457	0.4483	1.5044
X-24462	1.0422	0.9468
X-24473	1.1888	0.7647
X-24475	1.2170	0.7497
X-24518	1.1058	0.8718
X-24519	0.9162	1.1020
X-24522	1.1673	0.7932
X-24531	1.0532	0.9391
X-24728	0.9614	1.0476
X-24757	1.1290	0.8360
X-24763	0.9953	1.0059
X-24764	0.9277	1.0928
X-24801	1.0381	0.9524
X-24812	1.0988	0.8757
X-24970	1.0397	0.9507
X-24971	1.1175	0.8480
X-25044	1.0143	0.9824
X-25109	1.3389	0.5557
X-25172	0.9322	1.0834
X-25265	1.1326	0.8368
X-25267	0.9865	1.0172
X-25271	1.1020	0.8643
X-25343	1.1399	0.8278
X-25417	1.1658	0.8040
X-25419	1.1619	0.8207
X-25420	1.1271	0.8393
X-25422	1.0025	0.9969
X-25519	1.0422	0.9516
X-25520	1.2364	0.6667
X-25790	0.9190	1.0997
X-25810	1.1042	0.8717
X-25948	1.2544	0.6908
X-25957	1.0172	0.9785
X-25983	1.1802	0.7368
X-26008	1.0757	0.9092
X-26058	1.1782	0.8341
X-26097	0.9465	1.0659
X-26235	1.0190	0.9593
xanthurenate	0.9704	1.0320
zolpidem	1.2101	0.4748

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1	Timepoint:Day 0 | Sample source:plasma
F2	Timepoint:Day 2 | Sample source:plasma