Data for (Study ST004333)

(Analysis AN007235)

Values for each metabolite have been scaled by dividing by the mean across all factors

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Metabolite	F1	F2
10Z-Heptadecenoic acid	0.7537	1.3623
11(R)-HETE isomer	0.6771	1.4878
1-Oxo-14_17_20_23-tetraoxa-2-thiapentacosan-25-oic acid isomer	1.0388	1.1247
2-dehydrogluconate	1.0044	1.1585
2-Hydroxybutyric acid	1.1604	1.0038
2-Hydroxyvaleric acid	1.4679	0.6937
2-keto-isocaproate	1.8794	0.2867
2-keto-isovalerate	1.4717	0.6020
2-O-Methylascorbic acid	1.0563	1.1103
2-Phenylpropionate	0.9550	1.1312
3-(2-(4-Nitrobenzoyl)hydrazinyl)propane-1-sulfonic acid isomer 2	1.8881	0.1119
3_4-Dihydroxyhydrocinnamic acid	1.2459	0.9191
3-Methoxy-4-hydroxyphenylethyleneglycol sulfate	1.0121	0.9879
3-Methylcrotonylglycine	1.9858	0.1781
3-Phosphoglyceric acid	2.1234	0.0432
4-Acetylbutyrate isomer	1.8788	0.2872
4-Hydroxyproline	1.5747	0.5919
4-Methyleneglutamic acid isomer	1.5817	0.5844
4-Pyridoxic acid	1.1472	1.0185
5,6-Dihydrouridine	1.2741	0.8923
5-Keto-D-gluconate	0.6472	1.5179
6-Phosphogluconic acid	2.1207	0.0455
7Z,10Z-Hexadecadienoic acid	0.3630	1.8019
acetoacetate	0.2773	1.8755
ADP	1.9608	0.0392
Adrenic acid	0.1372	1.8628
a-ketoglutarate	1.6120	0.5545
Allantoin	1.1882	0.9784
Arabinonic acid isomer	1.4105	0.7544
Arachidonic acid	0.0657	2.0971
Ascorbic acid	2.0380	0.1274
Aspartyl-Glycine	1.8758	0.1242
CDP	1.9741	0.0259
Cervonic acid	0.1785	1.8215
Cholesterol sulfate	1.0626	1.1039
Cinnamoylglycine	1.0833	1.0828
cis-Aconitic acid	1.3648	0.8014
Citraconic acid	1.3604	0.8055
citrate	1.6352	0.5261
Creatine	1.1312	1.0353
Creatinine	1.2170	0.9493
Cyclic ADP-ribose	1.9718	0.0282
Cysteine-S-sulfate	0.9785	1.1879
Deoxyuridine	2.0581	0.1079
D-Fructose	1.0418	1.1245
D-Glucose	0.9220	1.2447
D-glyceraldehyde-3-phosphate	1.9446	0.0554
Docosadienoate (22:2n6)	0.9825	1.0175
Docosyl 4-hydroxybenzoate isomer	1.6309	0.5351
D-Sedoheptulose 7-phosphate	1.8945	0.1055
Eicosadienoic acid	0.4889	1.6776
Eicosapentaenoic acid	0.1943	1.9095
Erucic acid	1.4441	0.7130
FA(19:1)	0.8808	1.2702
FA(20:3)	0.1406	2.0260
FA(22:3)	0.6872	1.3128
FA(22:5)	0.1126	1.8874
FA(24:2)	1.0925	0.9075
Folic acid	1.2854	0.7146
Fructose 1,6-bisphosphate	1.9212	0.0788
Fumaric acid	1.9975	0.1690
Gadoleic acid	0.9976	1.1610
gamma-Linolenic acid	0.4900	1.6765
Gln-Glu isomer	1.5462	0.6194
Glucose 6-phosphate	2.0501	0.1164
Glu-Gly isomer	2.1011	0.0652
Glutaconic acid	1.3615	0.8044
Glutamylaspartic acid isomer	1.8482	0.1518
Glyceric acid	1.1824	0.9705
Glycerol 3-phosphate	1.8154	0.3506
Glycerophosphoinositol	1.9673	0.0327
Glycine	1.6167	0.5498
Glycolic acid	1.2474	0.9021
Guaiacol sulfate	1.0547	0.9453
Guanosine diphosphate	1.9592	0.0408
Hydroxyisocaproic acid	1.4299	0.6945
Hypotaurine	1.9227	0.0773
Imidazolelactate isomer	1.7089	0.4573
Indole-3-carboxilic acid-O-sulphate	1.0286	0.9714
Indoxyl sulfate	1.1287	1.0377
Isocaproic acid	0.8616	1.2770
Lactic acid	1.7416	0.4250
L-Alanine	1.2466	0.9199
L-Aspartic acid	1.4942	0.6724
L-Homoserine	1.0202	1.1463
Lignoceric acid	0.6280	1.4884
Linoleic acid	0.4503	1.7109
Lithocholyltaurine	1.0366	0.9634
L-Threonine	1.0222	1.1443
L-Valine	0.9760	1.1906
LysoPI(0:0/18:0)	2.1040	0.0625
LysoPI(16:0/0:0)	2.1515	0.0150
LysoPI(18:1(9Z)/0:0)	1.9806	0.0229
lysoPS(22:0)	0.9076	1.0924
Malic acid	2.0644	0.1021
Malonic acid	1.7330	0.3896
Methyl beta-glucuronide isomer	1.0262	1.1364
Methyl farnesoate isomer	0.1936	1.9440
Methylmalonic acid	1.3301	0.8349
myo-Inositol	1.2088	0.9576
Myristic acid	1.3016	0.8394
Myristoleic acid	0.8100	1.3489
N-Acetylasparagine	1.4993	0.6673
N-acetyl-asp isomer	1.5687	0.5978
N-Acetylglutamine	2.0917	0.0736
N-Acetyl-L-alanine	2.0514	0.1147
N-Acetyl-L-methionine	1.9887	0.0113
N-Acetylthreonine	1.9139	0.2525
N-Acetylvaline/2-Methylbutyrlglycine/Isovalerylglycine	1.0837	1.0807
Nervonic acid	1.1955	0.9694
N-Formyl-L-aspartate	1.8469	0.3194
N-Formyl-L-methionine	0.9402	1.0598
N-Gluconyl ethanolamine isomer	1.0209	1.1439
octulose-8-phosphate	1.9615	0.0385
Oleic acid	0.7734	1.3801
Orotic acid	2.1233	0.0425
O-Succinyl-L-homoserine isomer	2.1129	0.0534
Oxalic acid	0.4863	1.6434
Palmitoleic acid	0.8046	1.3456
Pantothenic acid	1.4266	0.5734
p-Cresol sulfate	1.1262	1.0404
PG(16:1(9Z)/16:0)	1.7747	0.0703
PG(18:1(11Z)/16:0)	1.5457	0.4543
PG(18:1(11Z)/18:2(9Z,12Z))	0.4887	1.5113
PG(18:2(9Z,12Z)/18:2(9Z,12Z))	0.7167	1.2833
PG(20:4(5Z,8Z,11Z,14Z)/18:1(11Z))	0.3832	1.6168
Phenol sulphate	1.1438	1.0228
Phosphate	1.1365	1.0129
Phosphoenolpyruvic acid	1.9558	0.0442
Proline	1.5428	0.6239
Propionylglycine	1.5748	0.5918
Pro-Ser isomer	2.0815	0.0842
PS(18:0/18:0)	1.7991	0.2009
Pseudouridine	1.2048	0.7952
Pyrocatechol sulfate	1.1576	1.0089
Pyroglutamic acid	1.1898	0.9768
Pyruvic acid	1.4502	0.7150
Ribitol	1.2918	0.8746
ribose-5-phosphate	1.9688	0.1975
(S)-3-Hydroxyisobutyric acid	1.0006	1.1617
S-3-oxodecanoyl cysteamine	1.8725	0.1275
Serine	1.0567	1.1099
Sorbitol	1.2972	0.8682
Succinic acid	1.3301	0.8348
Sulfate	1.0584	1.1068
Taurodeoxycholic acid	0.9565	1.0435
Taurodeoxycholic acid isomer	0.9680	1.0320
Tetracosatetraenoic acid (24:4n-6)	0.9436	1.0564
Thymidine	1.8962	0.2703
trans-Cinnamate	0.9467	1.2199
Uracil	0.2053	1.9601
Ureidosuccinic acid	2.1629	0.0037
Uridine	0.2364	1.9301
Uridine 5^-diphosphate	1.9816	0.0184
Uridine diphosphate glucose	1.9735	0.0265
Uridine diphosphate glucuronic acid	1.8078	0.0306
Uridine triphosphate	1.9841	0.0159
Xanthine	1.1537	1.0130

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Factors:

F1	Genotype:G6pd ctrl | Sample source:splenic CD8+ T cells
F2	Genotype:G6pd ko | Sample source:splenic CD8+ T cells