Data for (Study ST004339)
(Analysis AN007246)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3-HYDROXYMETHYLGLUTARATE | 1.2622 | 0.9823 | 0.8806 | 1.1585 | 0.4939 | 0.8513 | 1.0510 | 1.0847 | 1.0798 | 1.1558 | NA | NA | NA | NA | NA | NA |
| ADENINE | 0.9560 | 0.9192 | 0.7438 | 1.0532 | 1.0627 | 0.9064 | 1.0387 | 1.1380 | 1.1043 | 1.0777 | NA | NA | NA | NA | NA | NA |
| ADENOSINE 3^,5^-DIPHOSPHATE | 0.8496 | 1.0487 | 0.8610 | 1.1019 | 0.5837 | 0.9070 | 1.1111 | 1.0541 | 1.1715 | 1.3113 | NA | NA | NA | NA | NA | NA |
| ADENOSINE DIPHOSPHATE RIBOSE | 0.7957 | 1.1119 | 0.8891 | 1.1153 | 0.4121 | 1.0020 | 1.1569 | 1.1046 | 1.2004 | 1.2121 | NA | NA | NA | NA | NA | NA |
| ADENOSINE-MONOPHOSPHATE | 0.8666 | 0.7357 | 0.4308 | 0.8382 | 0.5922 | 1.0134 | 1.2423 | 1.4516 | 1.4147 | 1.4146 | NA | NA | NA | NA | NA | NA |
| ADP-GLUCOSE | 0.8537 | 0.9673 | 0.9139 | 0.8894 | 0.5933 | 1.1300 | 1.1411 | 1.0974 | 1.1875 | 1.2262 | NA | NA | NA | NA | NA | NA |
| ALLOTHREONINE | 1.0451 | 0.3912 | 0.4671 | 1.3040 | 0.5457 | 0.1721 | 0.7179 | 1.2769 | 2.0486 | 2.0314 | NA | NA | NA | NA | NA | NA |
| AMINOISOBUTANOATE | 0.9303 | 0.9523 | 1.0070 | 0.9710 | 0.7547 | 0.9839 | 1.0329 | 1.0303 | 1.1474 | 1.1901 | NA | NA | NA | NA | NA | NA |
| ANILINE-2-SULFONATE | NA | 0.6834 | 1.1691 | 1.2046 | 3.9416 | 0.6546 | 0.7689 | NA | 1.5451 | 0.7136 | NA | NA | NA | NA | NA | NA |
| ANSERINE | 0.8968 | 1.0149 | 1.1271 | 1.1342 | 1.1044 | 0.9370 | 0.9277 | 0.9365 | 0.9712 | 0.9502 | NA | NA | NA | NA | NA | NA |
| ASPARAGINE | 0.9797 | 1.0202 | 1.0617 | 0.9170 | 0.7959 | 1.0425 | 0.9773 | 0.9602 | 0.9807 | 1.2649 | NA | NA | NA | NA | NA | NA |
| ASPARTATE | 0.9754 | 1.0587 | 0.9880 | 1.0488 | 0.8355 | 1.0214 | 1.0394 | 0.9828 | 0.9982 | 1.0518 | NA | NA | NA | NA | NA | NA |
| BETA-GLYCEROPHOSPHATE | 0.8945 | 0.8976 | 0.6585 | 1.1020 | 0.8742 | 0.8215 | 0.8960 | 1.3323 | 1.1593 | 1.3641 | NA | NA | NA | NA | NA | NA |
| CARNOSINE | 0.9481 | 1.1162 | 1.2066 | 1.0218 | 0.8841 | 0.9409 | 0.9588 | 0.8853 | 1.0043 | 1.0339 | NA | NA | NA | NA | NA | NA |
| CDP-ETHANOLAMINE | 1.0796 | 1.1489 | 1.4718 | 0.9410 | 0.5363 | 0.9998 | 1.1381 | 0.8361 | 0.9053 | 0.9430 | NA | NA | NA | NA | NA | NA |
| CITICOLINE | 1.1911 | 1.0769 | 0.9591 | 0.9034 | 0.8027 | 1.2375 | 0.8176 | 1.0331 | 0.8288 | 1.1498 | NA | NA | NA | NA | NA | NA |
| CREATININE | 1.2777 | 0.8579 | 1.0599 | 0.9158 | 1.0285 | 0.9653 | 0.9041 | 0.8415 | 0.9859 | 1.1634 | NA | NA | NA | NA | NA | NA |
| CYCLIC AMP | 1.0038 | 0.9282 | 0.9408 | 1.0397 | 0.7180 | 0.9586 | 0.9991 | 1.0402 | 1.1463 | 1.2252 | NA | NA | NA | NA | NA | NA |
| DEOXYADENOSINE TRIPHOSPHATE | 0.8293 | 1.0763 | 0.9192 | 0.9910 | 0.5603 | 1.0036 | 1.1185 | 1.0822 | 1.1966 | 1.2232 | NA | NA | NA | NA | NA | NA |
| DEOXYCYTIDINE-DIPHOSPHATE | 0.9297 | 0.9085 | 0.9702 | 0.9402 | 0.8103 | 0.9553 | 1.1039 | 1.1286 | 1.1329 | 1.1203 | NA | NA | NA | NA | NA | NA |
| DEOXYCYTIDINE MONOPHOSPHATE | 0.8699 | 0.9045 | 0.7433 | 1.0064 | 0.6993 | 1.0044 | 1.0787 | 1.2282 | 1.1765 | 1.2889 | NA | NA | NA | NA | NA | NA |
| DIAMINOPIMELATE | 1.1566 | 1.0001 | 1.0498 | 1.1501 | 0.9379 | 0.9340 | 0.9252 | 0.9225 | 0.9655 | 0.9583 | NA | NA | NA | NA | NA | NA |
| DIHYDROOROTATE | 0.9106 | 0.9901 | 1.0998 | 1.1981 | 0.7784 | 0.8722 | 0.9711 | 1.0658 | 1.0696 | 1.0443 | NA | NA | NA | NA | NA | NA |
| DTDP-D-GLUCOSE | 1.1512 | 1.2900 | 1.1361 | 1.2946 | 0.7907 | 0.7544 | 0.8368 | 0.8864 | 0.8956 | 0.9642 | NA | NA | NA | NA | NA | NA |
| GAMMA-AMINOBUTYRATE | 1.0542 | 1.1461 | 1.1169 | 1.0549 | 0.8672 | 0.9113 | 0.9377 | 0.8709 | 0.9807 | 1.0600 | NA | NA | NA | NA | NA | NA |
| GLUCONATE | 0.9379 | 1.0332 | 1.0275 | 0.9802 | 0.6486 | 0.9545 | 1.0153 | 0.9992 | 1.1884 | 1.2152 | NA | NA | NA | NA | NA | NA |
| GLUCOSE 1-PHOSPHATE | 0.9230 | 0.8546 | 0.6913 | 1.0218 | 0.6592 | 0.9827 | 1.0121 | 1.3771 | 1.2881 | 1.1902 | NA | NA | NA | NA | NA | NA |
| GLUCOSE 6-PHOSPHATE | 0.9688 | 1.0286 | 1.1218 | 0.9529 | 0.7648 | 1.1265 | 1.0475 | 1.0542 | 1.0742 | 0.8605 | NA | NA | NA | NA | NA | NA |
| GLUTAMATE | 1.0685 | 0.9884 | 1.0233 | 0.9913 | 0.9931 | 0.9491 | 0.9335 | 0.9745 | 1.0307 | 1.0477 | NA | NA | NA | NA | NA | NA |
| GUANIDINOSUCCINATE | 1.0238 | 0.7380 | 0.5773 | 0.9522 | 1.1109 | 0.6992 | 0.9979 | 1.0743 | 1.4678 | 1.3586 | NA | NA | NA | NA | NA | NA |
| INOSINE | 1.3065 | 1.3801 | 1.6521 | 1.0531 | 0.5827 | 0.7313 | 0.8649 | 0.7933 | 0.8546 | 0.7815 | NA | NA | NA | NA | NA | NA |
| INOSINE MONOPHOSPHATE | 1.0441 | 0.9992 | 0.8870 | 0.9673 | 0.7306 | 1.0587 | 0.9434 | 1.0479 | 1.0730 | 1.2488 | NA | NA | NA | NA | NA | NA |
| ITACONATE | 1.0070 | 1.0583 | 1.0297 | 1.0502 | 0.7245 | 0.9683 | 0.9942 | 0.9713 | 1.0854 | 1.1112 | NA | NA | NA | NA | NA | NA |
| L-ALANINE | 0.9967 | 1.0339 | 0.9600 | 1.1520 | 0.7165 | 0.8879 | 1.0298 | 1.0552 | 1.1232 | 1.0447 | NA | NA | NA | NA | NA | NA |
| MALATE | 1.0095 | 1.0349 | 0.9671 | 1.0134 | 0.7871 | 1.0373 | 0.9779 | 1.0129 | 1.0245 | 1.1353 | NA | NA | NA | NA | NA | NA |
| N-ACETYLASPARTATE | 0.9474 | 0.6670 | 0.6088 | 0.9319 | 0.9667 | 0.6806 | 0.9311 | 1.0278 | 2.0167 | 1.2218 | NA | NA | NA | NA | NA | NA |
| N-ACETYLNEURAMINATE | 0.8834 | 1.0186 | 1.0131 | 0.8570 | 0.7275 | 1.0134 | 0.9556 | 0.9833 | 1.1252 | 1.4229 | NA | NA | NA | NA | NA | NA |
| N-ACETYLSERINE | 2.0510 | 2.9772 | 3.4232 | NA | NA | 0.7236 | NA | NA | 0.7690 | 3.5416 | NA | NA | NA | NA | NA | NA |
| NADP | 0.9219 | 1.1462 | 0.9653 | 1.0637 | 0.5255 | 0.8809 | 1.1841 | 1.1399 | 1.0545 | 1.1181 | NA | NA | NA | NA | NA | NA |
| O-PHOSPHOETHANOLAMINE | 1.0129 | 1.0775 | 0.9101 | 1.0843 | 0.6704 | 0.9514 | 0.9888 | 1.0164 | 1.0751 | 1.2131 | NA | NA | NA | NA | NA | NA |
| O-SUCCINYL-HOMOSERINE | 1.3653 | 1.0161 | 0.8176 | 1.1798 | 0.5190 | 0.9612 | 1.0971 | 0.9587 | 1.0812 | 1.0040 | NA | NA | NA | NA | NA | NA |
| PHOSPHOCREATINE | 1.0852 | 0.9712 | 0.9383 | 0.8499 | 0.9999 | 1.1160 | 0.7787 | 0.9109 | 0.9907 | 1.3592 | NA | NA | NA | NA | NA | NA |
| PTERIN | 0.9626 | 0.9569 | 1.0071 | 0.8108 | 0.7165 | 1.2070 | 1.1033 | 0.9647 | 1.0511 | 1.2200 | NA | NA | NA | NA | NA | NA |
| PURINE | 0.8848 | 0.9979 | 1.0007 | 0.8871 | 0.7071 | 1.2198 | 1.1335 | 1.0050 | 1.0369 | 1.1272 | NA | NA | NA | NA | NA | NA |
| PYROGLUTAMATE | 1.1548 | 0.7744 | 0.9096 | 1.2221 | 1.0158 | 0.8747 | 1.0174 | 0.9768 | 0.9986 | 1.0557 | NA | NA | NA | NA | NA | NA |
| QUINOLINATE | 0.9600 | 0.8147 | 0.6486 | 0.9880 | 0.9851 | 0.9100 | 1.0008 | 1.2296 | 1.1483 | 1.3149 | NA | NA | NA | NA | NA | NA |
| SALICYLATE | 1.4176 | 0.4168 | 1.2136 | 0.8177 | 0.6813 | 1.4605 | 1.8444 | 1.1127 | 0.6712 | 0.3642 | NA | NA | NA | NA | NA | NA |
| SUCCINATE | 1.1289 | 1.1142 | 1.3029 | 1.1456 | 0.9079 | 0.8306 | 0.8050 | 0.7342 | 0.9954 | 1.0353 | NA | NA | NA | NA | NA | NA |
| TAURINE | 0.9611 | 0.9980 | 0.9586 | 0.9595 | 0.8704 | 1.0294 | 1.0116 | 0.9941 | 1.1154 | 1.1018 | NA | NA | NA | NA | NA | NA |
| THYMIDINE-MONOPHOSPHATE | 0.9623 | 0.9560 | 0.7837 | 0.9300 | 0.7291 | 0.9982 | 1.1343 | 1.1612 | 1.1526 | 1.1928 | NA | NA | NA | NA | NA | NA |
| TRANS-4-HYDROXY-L-PROLINE | 1.2360 | 0.8635 | 0.9650 | 1.2610 | 0.7278 | 0.8359 | 0.8056 | 1.0757 | 0.9604 | 1.2693 | NA | NA | NA | NA | NA | NA |
| URATE | 0.9227 | 0.7719 | 0.6204 | 0.9778 | 1.0288 | 0.7736 | 0.8834 | 1.2463 | 1.3501 | 1.4249 | NA | NA | NA | NA | NA | NA |
| URIDINE MONOPHOSPHATE | 1.0481 | 0.8830 | 0.8646 | 1.0291 | 0.7967 | 0.8880 | 1.0259 | 1.0536 | 1.2331 | 1.1779 | NA | NA | NA | NA | NA | NA |
Factors:
| F1 | Treatment:BME-free (BSO) | Sample source:INS-1 cells | Injection order:10 |
| F2 | Treatment:BME-free (BSO) | Sample source:INS-1 cells | Injection order:11 |
| F3 | Treatment:BME-free (BSO) | Sample source:INS-1 cells | Injection order:3 |
| F4 | Treatment:BME-free (BSO) | Sample source:INS-1 cells | Injection order:4 |
| F5 | Treatment:BME-free (BSO) | Sample source:INS-1 cells | Injection order:7 |
| F6 | Treatment:BME-free (control) | Sample source:INS-1 cells | Injection order:12 |
| F7 | Treatment:BME-free (control) | Sample source:INS-1 cells | Injection order:13 |
| F8 | Treatment:BME-free (control) | Sample source:INS-1 cells | Injection order:14 |
| F9 | Treatment:BME-free (control) | Sample source:INS-1 cells | Injection order:5 |
| F10 | Treatment:BME-free (control) | Sample source:INS-1 cells | Injection order:6 |
| F11 | Treatment:MSe | Sample source:INS-1 cells | Injection order:17 |
| F12 | Treatment:MSe | Sample source:INS-1 cells | Injection order:18 |
| F13 | Treatment:MSe | Sample source:INS-1 cells | Injection order:19 |
| F14 | Treatment:quality control | Sample source:INS-1 cells | Injection order:15 |
| F15 | Treatment:quality control | Sample source:INS-1 cells | Injection order:2 |
| F16 | Treatment:quality control | Sample source:INS-1 cells | Injection order:8 |
