Data for (Study ST004440)
(Analysis AN007435)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 1/2-3-Bisphosphoglycerate | 1.4209 | 1.3602 | 0.7941 | 0.4249 |
| 1-4-beta-D-Xylan | 0.3686 | 0.3978 | 1.5821 | 1.6516 |
| 2/3-Phospho-D-glycerate | 1.3488 | 1.4331 | 0.7369 | 0.4812 |
| 2/3-Phospho-D-glycerate 13C3 | NA | 1.7020 | 0.3951 | 0.6004 |
| 2-Hydroxyglutarate/Citramalate | 0.7479 | 2.0842 | 0.3640 | 0.8040 |
| 2-Oxoglutarate | 0.8738 | 2.7511 | 0.1429 | 0.2322 |
| 2-Oxoglutarate 13C5 | 1.1936 | NA | 0.2255 | NA |
| 2S-5S-Methionine sulfoximine | 1.3801 | 0.0158 | 1.3566 | 0.0216 |
| 4-Acetamidobutanoate | 1.1707 | 1.4188 | 0.8139 | 0.5967 |
| 4-Pyridoxate | 0.7307 | 1.4912 | 0.8094 | 0.9687 |
| 5-6-Dihydrothymine | 0.8073 | 0.9576 | 1.2070 | 1.0281 |
| 5-6-Dihydrouracil | 0.7908 | 1.0338 | 1.0440 | 1.1314 |
| 5-Hydroxyindoleacetate | 1.2651 | 1.8255 | 0.4062 | 0.5032 |
| 5-Phospho-alpha-D-ribose 1-diphosphate | 0.9073 | 1.6604 | 0.7878 | 0.6445 |
| 5^-Phosphoribosyl-N-formylglycinamide | 0.0438 | 0.5969 | 0.6961 | 1.9460 |
| 6-Phospho-D-gluconate | 0.7819 | 0.7487 | 1.1733 | 1.2962 |
| (7Z-10Z-13Z-16Z-19Z)-Docosa-7-10-13-16-19-pentaenoic acid | 0.9446 | 0.8646 | 1.1445 | 1.0463 |
| (8Z-11Z-14Z)-Icosatrienoic acid | 1.1172 | 0.9369 | 0.9839 | 0.9621 |
| Adenylosuccinic acid | 0.5798 | 0.7209 | 1.1110 | 1.5883 |
| ADP | 1.0893 | 1.0720 | 0.9304 | 0.9083 |
| ADP-D-ribose | 1.7210 | 1.7564 | 0.0135 | 0.0182 |
| Allantoate | 0.5962 | 1.1566 | 1.0280 | 1.2192 |
| alpha-D-Ribose 1-phosphate | 0.8546 | 0.9154 | 1.1614 | 1.0686 |
| ATP | 1.6840 | 1.3955 | 0.5316 | 0.3889 |
| ATP 15N1 | 1.3226 | 1.7733 | 0.5007 | 0.4034 |
| Carnosine | 1.5418 | 1.1878 | 0.5563 | 0.7141 |
| CDP | 0.6948 | 1.6132 | 0.7036 | 0.9883 |
| Citrate | 1.0791 | 2.0637 | 0.3967 | 0.4605 |
| Citrate 13C2 | 1.4747 | 1.4108 | 0.3552 | 0.7594 |
| Citrate 13C3 | 3.0798 | 0.2485 | 0.5741 | 0.0976 |
| Citrate 13C4 | 1.8663 | 0.0288 | 0.3764 | NA |
| Citrate 13C5 | 1.7392 | NA | 0.2608 | NA |
| Creatinine | 1.2212 | 1.2518 | 0.6320 | 0.8950 |
| CTP | 0.9884 | 2.0365 | 0.4371 | 0.5380 |
| Cytidine | 1.4135 | 1.0953 | 0.7486 | 0.7425 |
| dCMP | 0.7619 | 1.0201 | 1.0363 | 1.1816 |
| Decanoic acid (caprate) | 1.0494 | 0.9533 | 0.9704 | 1.0270 |
| Dehydroascorbate | 0.8766 | 1.9135 | 0.4644 | 0.7455 |
| D-Erythrose 4-phosphate | NA | 0.0664 | 1.2765 | 0.9569 |
| D-Fructose 1-6-bisphosphate | 0.0332 | 0.0329 | 2.3146 | 1.6192 |
| D-Fructose 1-6-bisphosphate 13C3 | NA | 0.0083 | 0.0189 | 2.9728 |
| D-Fructose 1-6-bisphosphate 13C6 | 0.1089 | 0.1435 | 0.0666 | 3.6810 |
| D-Glucose | 1.0470 | 1.1025 | 0.9233 | 0.9272 |
| D-Glucose 13C6 | NA | 0.5480 | NA | 1.4520 |
| D-Glucose 6/1-phosphate | 0.0354 | 0.0424 | 2.3834 | 1.5387 |
| D-Glucose 6/1-phosphate 13C3 | NA | 0.0075 | 0.0122 | 2.9803 |
| D-Glucose 6/1-phosphate 13C6 | 0.0209 | 0.1139 | NA | 2.1308 |
| D-Glyceraldehyde 3-phosphate/Glycerone phosphate | 0.2196 | 0.3759 | 1.9055 | 1.4990 |
| D-Glyceraldehyde 3-phosphate/Glycerone phosphate 13C3 | 0.1206 | 0.2248 | 0.1713 | 2.6293 |
| Diphosphate | 0.7603 | 1.0421 | 0.6937 | 1.5039 |
| Docosahexaenoic acid | 0.9117 | 0.9888 | 1.0016 | 1.0979 |
| Dodecanedioic acid | 1.0059 | 1.0184 | 1.0175 | 0.9583 |
| Dodecanoic acid | 1.0664 | 0.9854 | 0.9005 | 1.0476 |
| D-Ribose | 0.4326 | 0.6077 | 1.5478 | 1.4119 |
| dTMP | 1.4989 | 1.3947 | 0.4987 | 0.6077 |
| Eicosapentaenoic acid | 1.1484 | 0.8489 | 0.9806 | 1.0221 |
| Eicosatetraenoic acid | 1.1094 | 0.7989 | 1.0723 | 1.0193 |
| Flavin mononucleotide | 0.6550 | 1.1183 | 0.7601 | 1.2341 |
| Fumarate | 0.5952 | 1.0664 | 0.9468 | 1.3916 |
| Fumarate 13C2 | 0.8297 | 0.1926 | 1.4433 | 1.5345 |
| Fumarate 13C4 | 1.3638 | 0.0247 | 1.6093 | 0.0333 |
| gamma-L-Glutamyl-D-alanine | 1.2058 | 1.8529 | 0.3666 | 0.5746 |
| gamma-L-Glutamylputrescine | 0.9821 | 1.0262 | 0.9907 | 1.0010 |
| GDP | 1.5172 | 1.0810 | 0.8123 | 0.5896 |
| Glutathione | 1.0390 | 1.3668 | 0.7629 | 0.8312 |
| Glutathione 13C3 | 2.2262 | 0.1221 | 1.5743 | 0.0774 |
| Glutathione 13C3 15N1 | 1.7295 | 0.1797 | 1.0779 | 0.2055 |
| Glutathione 13C4 | 1.4331 | 0.0680 | 0.7999 | NA |
| Glutathione 13C5 | 1.3791 | NA | 0.6209 | NA |
| Glutathione 13C5 15N1 | 2.0155 | 0.0674 | 0.9208 | 0.0526 |
| Glutathione 15N1 | 2.2435 | 0.3836 | 1.1183 | 0.2546 |
| Glycerol 3-phosphate | 1.3451 | 1.2015 | 0.7824 | 0.6710 |
| GMP | 0.6795 | 0.9444 | 1.1064 | 1.2697 |
| g-Oxalo-crotonate | 0.8734 | 1.6228 | 0.9128 | 0.5911 |
| GTP | 1.6769 | 1.5134 | 0.3819 | 0.4278 |
| Heptanoic acid | 1.0254 | 1.0011 | 0.9436 | 1.0300 |
| Hexadecanoic acid | 1.0852 | 0.9457 | 0.8888 | 1.0803 |
| Hexadecenoic acid | 1.2828 | 1.0178 | 0.8512 | 0.8482 |
| Hexanoic acid (caproate) | 0.9782 | 1.0298 | 0.9665 | 1.0254 |
| Hypoxanthine | 1.0563 | 1.6848 | 0.5096 | 0.7493 |
| IMP | 0.8959 | 1.2495 | 1.0727 | 0.7819 |
| Inosine | 0.6584 | 1.0304 | 0.9890 | 1.3221 |
| Itaconate | 0.8160 | 1.9246 | 0.4644 | 0.7950 |
| Lactate | 1.1552 | 1.0976 | 0.8033 | 0.9439 |
| Lactate 13C3 | 0.0364 | 1.5437 | 0.0295 | 2.3904 |
| L-aspartate | 0.5169 | 0.7629 | 1.2258 | 1.4944 |
| L-cystine | 1.0131 | 1.6079 | 0.8436 | 0.5354 |
| L-histidine | 0.8633 | 1.1265 | 0.9554 | 1.0548 |
| Linoleate | 1.2740 | 0.9603 | 0.8738 | 0.8919 |
| Malate | 0.4857 | 1.1335 | 1.0094 | 1.3715 |
| Malate 13C2 | 0.6727 | 0.3580 | 1.5760 | 1.3933 |
| Malate 13C3 | 2.0119 | 0.1072 | 1.5828 | 0.2981 |
| Malate 13C4 | 0.9597 | 0.0016 | 1.5395 | 0.0015 |
| Mannitol/Sorbitol | 0.1052 | 0.1497 | 1.9680 | 1.7771 |
| N-Acetylneuraminate | 1.0212 | NA | 0.9788 | NA |
| NAD+ | 1.0946 | 0.9054 | NA | NA |
| NAD+ 13C2 | 1.0766 | 0.9234 | NA | NA |
| NAD+ 15N1 | 1.0646 | 0.9354 | NA | NA |
| NADH | 1.0766 | 0.9234 | NA | NA |
| Nonanoic acid (pelargonate) | 1.0267 | 0.9842 | 0.9426 | 1.0465 |
| N-Succinyl-L-glutamate 5-semialdehyde | 1.2449 | 1.7120 | 0.4670 | 0.5761 |
| Octadecanoic acid | 1.0709 | 0.9465 | 0.9263 | 1.0564 |
| Octadecatrienoic acid | 1.0529 | 1.0208 | 1.0107 | 0.9156 |
| Octadecenoic acid | 1.1461 | 0.9772 | 0.8907 | 0.9859 |
| Octanoic acid (caprylate) | 1.0064 | 0.9683 | 0.8883 | 1.1370 |
| Phosphate | 0.7698 | 0.9495 | 0.8967 | 1.3840 |
| Phosphoenolpyruvate | 0.8690 | 0.8345 | 1.3439 | 0.9527 |
| Phosphoenolpyruvate 13C2 | 0.5942 | 1.7787 | 0.6526 | 0.8876 |
| Pyridoxal | 0.8723 | 1.0114 | 1.0007 | 1.1155 |
| Pyruvate | 0.7179 | 0.6712 | 1.3393 | 1.2716 |
| S-Adenosyl-L-homocysteine | 0.5645 | 0.8073 | 1.0326 | 1.9097 |
| (S)(+)-Allantoin | 1.0194 | 1.2589 | 0.6220 | 1.0997 |
| Sedoheptulose 1/7-phosphate | 0.0753 | 0.0851 | 2.3195 | 1.5201 |
| Sedoheptulose 1/7-phosphate 13C3 | 0.2337 | 0.0406 | 0.0537 | 2.8157 |
| Sedoheptulose 1/7-phosphate 13C4 | 0.1577 | 0.1608 | NA | 2.2612 |
| Succinate | 1.4632 | 1.6761 | 0.3291 | 0.5316 |
| Succinate 13C4 | 3.0693 | 0.3499 | 0.2326 | 0.3482 |
| Taurine | 1.0719 | 1.2390 | 0.8710 | 0.8180 |
| Tetradecanoic acid | 1.0955 | 0.9413 | 0.8934 | 1.0697 |
| Tetradecenoic acid | 1.0216 | 1.0800 | 0.8088 | 1.0896 |
| Thymidine | 1.1723 | 1.1015 | 0.8737 | 0.8525 |
| UDP | 1.0440 | 0.8992 | 0.7972 | 1.2596 |
| UDP-glucose | 1.2540 | 1.5074 | 0.6581 | 0.5805 |
| UDP-N-acetyl-D-glucosamine | 1.3649 | 1.7643 | 0.4719 | 0.3989 |
| UMP | 0.4029 | 1.0742 | 1.1702 | 1.3526 |
| Uracil | 1.3971 | 1.0954 | 0.8138 | 0.6937 |
| Urate | 1.3981 | 1.4444 | 0.5026 | 0.6548 |
| UTP | 1.0452 | 1.9302 | 0.4508 | 0.5738 |
| Xanthine | 2.2549 | 1.0101 | 0.3205 | 0.2193 |
Factors:
| F1 | Treatment:DMSO | Timepoint:12H | Sample source:MDS-L Cells |
| F2 | Treatment:DMSO | Timepoint:3H | Sample source:MDS-L Cells |
| F3 | Treatment:OT | Timepoint:12H | Sample source:MDS-L Cells |
| F4 | Treatment:OT | Timepoint:3H | Sample source:MDS-L Cells |
