Data for (Study ST003820)
(Analysis AN007471)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 2-hydroxyglutarate | 0.8056 | 0.9652 | 1.3834 | 0.8458 |
| 3-methyl-2-oxopentanoic_acid | 0.8751 | 1.2960 | 0.8484 | 0.9805 |
| 3-phosphoglycerate | 1.0186 | 1.2991 | 0.7175 | 0.9647 |
| acetylcarnitine | 0.9131 | 0.6530 | 1.2588 | 1.1750 |
| Acetyl.CoA | 1.1930 | 1.0344 | 0.7788 | 0.9938 |
| alanine | 1.0235 | 1.1359 | 0.9199 | 0.9207 |
| Alpha.Ketoglutarate | 0.7825 | 1.3387 | 0.8453 | 1.0334 |
| amidoadipate | 1.0037 | 1.0938 | 0.9451 | 0.9574 |
| AMP | 0.7183 | 0.8045 | 1.7368 | 0.7404 |
| argininosuccinate | 0.7700 | 1.0065 | 1.1127 | 1.1108 |
| ascorbate | 0.9318 | 1.2224 | 0.9536 | 0.8922 |
| asparagine | 1.1765 | 1.1855 | 0.6955 | 0.9426 |
| aspartate | 1.3136 | 1.1228 | 0.4083 | 1.1552 |
| asymmetric.dimethylarginine | 0.9261 | 1.0282 | 0.8780 | 1.1677 |
| ATP | 1.0437 | 1.0291 | 0.8215 | 1.1056 |
| beta.alanine | 0.9429 | 1.1749 | 0.9306 | 0.9515 |
| betaine | 1.1145 | 0.9716 | 0.7794 | 1.1346 |
| Butyrylcarnitine | 0.9318 | 0.9050 | 1.0348 | 1.1284 |
| C5.Carnitines | 0.5613 | 0.4144 | 2.1213 | 0.9030 |
| carnitine | 0.9402 | 0.8267 | 1.1576 | 1.0756 |
| CDP | 0.8482 | 0.8241 | 1.2067 | 1.1210 |
| CDP.choline | 1.1146 | 0.6726 | 1.4226 | 0.7902 |
| citrate | 0.9329 | 1.3195 | 0.5945 | 1.1531 |
| citrulline | 1.1552 | 1.0262 | 0.9042 | 0.9144 |
| creatine | 1.0067 | 1.0848 | 0.8796 | 1.0289 |
| creatinine | 1.1077 | 0.9178 | 0.9048 | 1.0697 |
| CTP | 1.3799 | 1.1126 | 0.5028 | 1.0047 |
| cystathionine | 1.1409 | 1.1087 | 0.7626 | 0.9879 |
| dATP | 1.1945 | 1.0661 | 0.7160 | 1.0234 |
| dCTP | 1.1564 | 1.1103 | 0.5085 | 1.2248 |
| dihydroorotate | 0.1610 | 0.1356 | 3.3650 | 0.3384 |
| dihydroxyacetone_phosphate | 0.6768 | 0.9522 | 1.5210 | 0.8500 |
| dTMP | 1.1142 | 1.0857 | 0.8440 | 0.9562 |
| dTTP | 1.3912 | 0.8440 | 0.6282 | 1.1366 |
| F6P_andor_G1P | 1.0183 | 1.4315 | 0.8712 | 0.6790 |
| FAD | 1.1639 | 0.8638 | 0.8970 | 1.0753 |
| formyl_methionine | 0.9844 | 0.9997 | 1.1451 | 0.8707 |
| Fructose.1.6.bisphosphate | 1.1210 | 1.2645 | 0.7166 | 0.8980 |
| fumarate | 0.8256 | 1.0755 | 1.0237 | 1.0753 |
| gamma.aminobutyric_acid | 1.0236 | 1.2295 | 0.7917 | 0.9552 |
| GDP | 0.8552 | 0.8809 | 1.4317 | 0.8322 |
| glutamate | 1.1032 | 1.1467 | 0.7422 | 1.0079 |
| glutamine | 1.1704 | 1.2394 | 0.6534 | 0.9368 |
| glyceraldehyde_3.phosphate | 0.6768 | 0.9522 | 1.5210 | 0.8500 |
| glycerate | 1.1879 | 1.0842 | 0.7800 | 0.9479 |
| Glycerophosphocholine | 1.3975 | 1.1795 | 0.4764 | 0.9467 |
| GMP | 0.4443 | 0.4185 | 2.4644 | 0.6728 |
| GSH_Ellmans | 1.1452 | 1.0201 | 0.8364 | 0.9984 |
| GSSG | 0.6554 | 1.5583 | 0.8577 | 0.9286 |
| GTP | 1.0006 | 1.3066 | 0.7798 | 0.9130 |
| histidine | 1.1235 | 1.1156 | 0.8588 | 0.9021 |
| homocitrulline | 0.9637 | 1.2206 | 0.8839 | 0.9319 |
| hypotaurine | 1.2047 | 0.8673 | 1.1478 | 0.7801 |
| IMP | 0.4600 | 0.8977 | 1.9933 | 0.6490 |
| isoleucine | 1.0886 | 0.8517 | 1.0111 | 1.0486 |
| lactic_acid | 0.7563 | 0.9042 | 1.3778 | 0.9617 |
| leucine | 1.1388 | 0.8261 | 0.9134 | 1.1217 |
| malate | 0.8745 | 1.0983 | 1.0000 | 1.0272 |
| mannose | 1.2517 | 1.1439 | 0.5153 | 1.0890 |
| methionine | 1.1164 | 0.8711 | 1.0150 | 0.9975 |
| methylthioadenosine | 1.0271 | 0.9992 | 0.9240 | 1.0497 |
| N.acetylglutamate | 1.1346 | 1.2748 | 0.8246 | 0.7660 |
| NAD. | 1.1165 | 1.1485 | 0.8079 | 0.9271 |
| NADH | 0.8601 | 0.9227 | 1.4267 | 0.7904 |
| NADP | 0.9499 | 1.0053 | 0.9302 | 1.1147 |
| NADPH | 1.0064 | 1.1528 | 0.7729 | 1.0679 |
| niacinamide | 0.9421 | 0.9491 | 0.8884 | 1.2204 |
| O.phosphoethanolamine | 0.7636 | 0.4186 | 2.4727 | 0.3450 |
| ornithine | 0.9856 | 1.0014 | 0.8593 | 1.1537 |
| palmitate | 1.2939 | 0.8692 | 0.6911 | 1.1458 |
| phosphocholine | 1.1109 | 1.2082 | 0.7173 | 0.9637 |
| phosphocreatine | 1.1457 | 1.2091 | 0.7270 | 0.9182 |
| phosphoenolpyruvate | 1.0850 | 1.4551 | 0.4367 | 1.0232 |
| Pipecolate | 1.0006 | 0.8606 | 0.8970 | 1.2419 |
| proline | 1.0531 | 1.0107 | 0.9521 | 0.9840 |
| propionylcarnitine | 0.8586 | 0.9279 | 0.7305 | 1.4830 |
| Pyridoxine | 1.0787 | 0.9126 | 0.8950 | 1.1137 |
| Ribose.Ribulose.5.phosphate.3Me.Lys | 0.8180 | 1.3813 | 0.8013 | 0.9993 |
| saccharopine | 0.2236 | 0.2533 | 0.1292 | 3.3940 |
| S.Adenosyl.L.Homocysteine | 1.0376 | 0.9560 | 0.9055 | 1.1010 |
| S.Adenosyl.L.methionine | 1.1458 | 1.0145 | 0.8657 | 0.9740 |
| Sedoheptulose.7.phosphate | 0.8697 | 1.0842 | 1.4247 | 0.6214 |
| serine | 1.3313 | 1.0616 | 0.7112 | 0.8958 |
| sorbitol | 1.0223 | 1.1682 | 0.8881 | 0.9215 |
| succinate | 0.6288 | 0.7687 | 1.8710 | 0.7315 |
| taurine | 1.0640 | 1.0803 | 0.9230 | 0.9327 |
| threonine | 1.0989 | 1.1213 | 0.6907 | 1.0891 |
| trans.urocanate | 1.6444 | 0.6851 | 0.5903 | 1.0802 |
| tryptophan | 1.1380 | 0.9064 | 1.0020 | 0.9536 |
| tyrosine | 1.2033 | 0.8998 | 0.9124 | 0.9846 |
| UDP | 0.8736 | 0.8480 | 1.1607 | 1.1178 |
| UDP.GlcNAc | 1.0965 | 1.3236 | 0.5716 | 1.0083 |
| UMP | 0.6940 | 0.7278 | 1.4941 | 1.0842 |
| Ureidosuccinic_acid | 0.1540 | 0.1446 | 3.4172 | 0.2841 |
| uric.acid | 1.2068 | 1.1640 | 0.6472 | 0.9820 |
| UTP | 1.1469 | 1.2009 | 0.5777 | 1.0746 |
| valine | 1.1801 | 0.8017 | 0.8592 | 1.1590 |
| xanthine | 1.0997 | 0.9760 | 0.8117 | 1.1126 |
Factors:
| F1 | Sample source:SEM leukemia cells | sgRNA:Intergenic1 | overexpression:GFP |
| F2 | Sample source:SEM leukemia cells | sgRNA:Intergenic1 | overexpression:SLC31A1 |
| F3 | Sample source:SEM leukemia cells | sgRNA:SLC31A1_#2 | overexpression:GFP |
| F4 | Sample source:SEM leukemia cells | sgRNA:SLC31A1_#2 | overexpression:SLC31A1 |
