Data for (Study ST003822)
(Analysis AN007474)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 2-hydroxyglutarate | 1.1611 | 0.9147 | 0.8778 | 0.9427 |
| 2-oxobutyric_acid | 0.9496 | 0.9649 | 0.8426 | 1.1467 |
| 3-phosphoglycerate | 0.4905 | 1.5699 | 0.7799 | 1.3346 |
| acetylcarnitine | 0.9729 | 0.9948 | 1.0454 | 1.0070 |
| Acetyl.CoA | 1.0290 | 1.0153 | 0.9931 | 0.9669 |
| adenine | 1.0323 | 0.8796 | 1.3490 | 0.8534 |
| ADP | 1.1249 | 1.0299 | 0.8792 | 0.9205 |
| alanine | 1.0560 | 0.8441 | 1.0973 | 0.9733 |
| AMP | 0.8951 | 0.9312 | 1.2382 | 1.0202 |
| arginine | 1.0484 | 0.9688 | 0.9601 | 0.9872 |
| argininosuccinate | 0.7109 | 0.8850 | 1.3576 | 1.1678 |
| asparagine | 1.1429 | 0.9611 | 0.8786 | 0.9372 |
| aspartate | 1.8686 | 0.7667 | 0.4290 | 0.5335 |
| asymmetric.dimethylarginine | 0.9800 | 0.9936 | 1.0459 | 1.0003 |
| beta.alanine | 0.8214 | 0.9189 | 1.2025 | 1.1179 |
| Butyrylcarnitine | 0.9968 | 1.0625 | 0.9857 | 0.9791 |
| C5.Carnitines | 0.5904 | 0.5282 | 1.7538 | 1.2686 |
| Carbamoyl Aspartic Acid | 0.3729 | NA | 1.4692 | 1.1579 |
| carnitine | 0.9527 | 1.0595 | 0.9608 | 1.0371 |
| carnosine | 1.0923 | 0.8741 | 1.1017 | 0.9198 |
| CDP | 1.1577 | 1.1025 | 0.8225 | 0.8798 |
| cis.aconitate | 0.9745 | 1.1135 | 0.8824 | 1.0276 |
| citrate | 0.9050 | 1.1499 | 0.9536 | 1.0432 |
| citrulline | 1.0057 | 0.9882 | 0.9682 | 1.0160 |
| creatine | 0.9814 | 0.9739 | 1.0667 | 0.9983 |
| cystathionine | 1.1271 | 0.9709 | 0.9087 | 0.9330 |
| Cysteine_Ellmans_conjugated | 1.1645 | 0.8265 | 0.9965 | 0.9240 |
| dihydroorotate | 0.2913 | NA | 2.0783 | 1.2543 |
| dihydroxyacetone_phosphate | 0.3083 | 1.1695 | 1.4599 | 1.3770 |
| F6P_or_G1P | 0.5055 | 1.4107 | 0.9105 | 1.3339 |
| FAD | 0.9659 | 1.0443 | 0.9880 | 1.0179 |
| fructose | 0.9853 | 1.0413 | 0.8931 | 1.0475 |
| Fructose.1.6.bisphosphate | 0.8261 | 1.4968 | 0.6772 | 1.0869 |
| fumarate | 0.8423 | 0.8557 | 1.2939 | 1.0829 |
| GDP | 0.9118 | 1.0359 | 1.0005 | 1.0700 |
| glutamate | 1.2653 | 0.9799 | 0.8046 | 0.8425 |
| glutamine | 1.4071 | 0.9190 | 0.7133 | 0.7767 |
| Glycerol.3.Phosphate | 0.3950 | 0.9926 | 1.4763 | 1.3706 |
| Glycerophosphocholine | 1.2333 | 1.0902 | 0.7158 | 0.8637 |
| glycine | 1.1089 | 1.0426 | 0.8371 | 0.9513 |
| GMP | 0.7217 | 0.9475 | 1.3552 | 1.1269 |
| GSH_Ellmans | 1.0533 | 1.0392 | 0.9243 | 0.9650 |
| GSSG | 1.0461 | 1.0191 | 0.9533 | 0.9678 |
| histidine | 1.0779 | 0.9603 | 0.9894 | 0.9472 |
| homocitrulline | 0.8935 | 1.0025 | 1.1974 | 1.0065 |
| hypotaurine | 1.1145 | 0.9291 | 1.0296 | 0.9061 |
| IMP | 0.1769 | 0.9926 | 1.5881 | 1.5327 |
| isoleucine | 1.1061 | 0.9205 | 1.0353 | 0.9160 |
| kynurenine | 0.8875 | 0.8750 | 1.2319 | 1.0590 |
| leucine | 1.0615 | 0.9815 | 1.0171 | 0.9392 |
| lysine | 1.1082 | 0.9311 | 0.9463 | 0.9531 |
| malate | 0.8349 | 0.8889 | 1.2501 | 1.0956 |
| mannose | 0.9859 | 1.0402 | 0.8937 | 1.0471 |
| methionine | 1.2008 | 0.8745 | 0.8823 | 0.9208 |
| Methionine.sulfoxide | 1.1045 | 0.9596 | 0.9838 | 0.9238 |
| methylthioadenosine | 0.9775 | 1.1110 | 1.0098 | 0.9621 |
| NAD. | 1.0560 | 1.0353 | 0.9189 | 0.9669 |
| NADH | 0.6922 | 0.9682 | 1.2689 | 1.1893 |
| NADP | 1.0689 | 0.9485 | 1.0128 | 0.9504 |
| NADPH | 1.1201 | 0.9696 | 0.9485 | 0.9208 |
| niacinamide | 1.0497 | 1.0335 | 0.7736 | 1.0468 |
| ornithine | 1.1066 | 0.9674 | 0.9111 | 0.9542 |
| palmitate | 1.0205 | 0.8095 | 0.7030 | 1.2232 |
| phosphocholine | 1.1183 | 1.0854 | 0.8474 | 0.9153 |
| phosphocreatine | 1.1865 | 0.9043 | 1.0039 | 0.8594 |
| phosphoenolpyruvate | 0.6179 | 1.8115 | 0.5644 | 1.1941 |
| proline | 0.8750 | 1.0502 | 1.0562 | 1.0718 |
| propionylcarnitine | 1.2916 | 1.1729 | 0.5511 | 0.8464 |
| Pyridoxine | 1.0082 | 1.0918 | 0.9300 | 0.9809 |
| S.Adenosyl.L.Homocysteine | 1.0544 | 1.0142 | 0.9815 | 0.9477 |
| S.Adenosyl.L.methionine | 1.0046 | 1.0373 | 0.9548 | 0.9993 |
| sarcosine | 1.0608 | 0.8352 | 1.1035 | 0.9698 |
| Sedoheptulose.7.phosphate | 0.4433 | 1.3908 | 1.1087 | 1.3069 |
| serine | 1.3478 | 0.8184 | 0.7821 | 0.8519 |
| succinate | 0.7931 | 0.7447 | 1.3258 | 1.1716 |
| succinyl.CoA | 1.5085 | 1.2486 | 0.2878 | 0.7233 |
| taurine | 0.9463 | 0.9987 | 1.0581 | 1.0253 |
| threonine | 1.6870 | 0.6921 | 0.6406 | 0.6466 |
| trans.urocanate | 1.2597 | 1.4570 | 0.7040 | 0.6598 |
| tryptophan | 1.1338 | 0.8813 | 0.9121 | 0.9694 |
| tyrosine | 1.2628 | 0.8780 | 0.8715 | 0.8625 |
| UDP | 1.1734 | 1.0670 | 0.8387 | 0.8737 |
| UDP.GlcNAc | 1.2856 | 0.9459 | 0.8401 | 0.8214 |
| UMP | 0.9730 | 1.0361 | 1.1082 | 0.9548 |
| valine | 1.1253 | 0.9642 | 1.0084 | 0.8883 |
| xanthosine | 0.9620 | 1.0890 | 0.9318 | 1.0276 |
Factors:
| F1 | Sample source:SEM leukemia cells | guideRNA:Intergenic1 | overexpression:RFP |
| F2 | Sample source:SEM leukemia cells | guideRNA:SLC31A1 guide #2 | overexpression:AOX |
| F3 | Sample source:SEM leukemia cells | guideRNA:SLC31A1 guide #2 | overexpression:RFP |
| F4 | Sample source:SEM leukemia cells | guideRNA:SLC31A1 guide #7 | overexpression:AOX |
