Data for (Study ST003823)
(Analysis AN007475)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 2-hydroxyglutarate | 1.0445 | 1.0068 | 0.9925 | 0.9561 |
| 3-methyl.2.oxopentanoic_acid | 1.0376 | 0.5850 | 1.2105 | 1.1668 |
| 3-phosphoglycerate | 1.7047 | 0.5208 | 0.9562 | 0.8183 |
| acetylcarnitine | 1.0007 | 1.0175 | 0.9878 | 0.9940 |
| Acetyl.CoA | 0.8829 | 0.7283 | 1.2293 | 1.1595 |
| ADP | 0.8052 | 1.3473 | 0.8391 | 1.0085 |
| alanine | 0.9146 | 0.9583 | 1.0606 | 1.0665 |
| Alpha.Ketoglutarate | 1.0161 | 0.4768 | 1.2779 | 1.2291 |
| AMP | 0.6669 | 2.1674 | 0.4885 | 0.6772 |
| arginine | 0.9854 | 0.8463 | 1.1102 | 1.0580 |
| argininosuccinate | 0.9536 | 0.8597 | 1.1326 | 1.0542 |
| ascorbate_unc | 1.0097 | 0.8936 | 1.0309 | 1.0659 |
| asparagine | 0.9036 | 0.8286 | 1.1347 | 1.1331 |
| aspartate | 0.8443 | 0.4192 | 1.3525 | 1.3841 |
| asymmetric.dimethylarginine | 0.9415 | 0.8207 | 1.1157 | 1.1221 |
| ATP | 0.9472 | 0.7874 | 1.1029 | 1.1626 |
| beta.alanine | 1.0747 | 1.0020 | 1.0238 | 0.8994 |
| betaine | 0.9365 | 0.7097 | 1.1728 | 1.1811 |
| Butyrylcarnitine | 0.9216 | 0.7777 | 1.1829 | 1.1178 |
| C5.Carnitines | 0.5024 | 1.1678 | 1.0844 | 1.2454 |
| carnitine | 1.0142 | 1.0451 | 0.9638 | 0.9769 |
| carnosine | 1.0249 | 0.9707 | 0.9566 | 1.0478 |
| CDP | 0.8468 | 0.9263 | 0.9807 | 1.2462 |
| CDP.choline | 1.5015 | 1.5616 | 0.4603 | 0.4766 |
| cis.aconitate | 1.0075 | 0.3614 | 1.2971 | 1.3340 |
| citrate | 1.0761 | 0.3295 | 1.3032 | 1.2911 |
| citrulline | 1.0396 | 0.9889 | 0.9446 | 1.0269 |
| CMP | 0.7123 | 1.5116 | 0.8271 | 0.9490 |
| creatine | 1.0462 | 0.9359 | 0.9834 | 1.0346 |
| creatinine | 1.0132 | 0.8835 | 1.0398 | 1.0635 |
| CTP | 1.0359 | 0.4150 | 1.2543 | 1.2948 |
| Cys_Ell | 1.2605 | 0.9545 | 0.8793 | 0.9057 |
| cystathionine | 0.8674 | 0.5269 | 1.3968 | 1.2089 |
| cytidine | 1.3813 | 1.3155 | 0.8715 | 0.4317 |
| dihydroorotate | 0.0563 | 3.5493 | 0.0215 | 0.3729 |
| dihydroxyacetone_phosphate | 1.4211 | 1.3157 | 0.6624 | 0.6008 |
| dTMP | 1.0695 | 0.9430 | 1.0075 | 0.9799 |
| F6P_or_G1P | 1.2106 | 1.6259 | 0.5863 | 0.5772 |
| FAD | 1.0011 | 0.9690 | 1.0640 | 0.9659 |
| Fructose.1.6.bisphosphate | 1.2606 | 0.7914 | 1.0339 | 0.9141 |
| fumarate | 0.9328 | 0.7600 | 1.2216 | 1.0856 |
| gamma.aminobutyric_acid | 1.0624 | 0.9085 | 0.9859 | 1.0432 |
| GDP | 0.7825 | 1.5855 | 0.7002 | 0.9318 |
| Glucose.6.phosphate | 0.9597 | 1.2696 | 0.8683 | 0.9023 |
| glutamate | 0.9399 | 0.7936 | 1.1476 | 1.1190 |
| glutamine | 0.9088 | 0.8442 | 1.1158 | 1.1311 |
| glyceraldehyde_3.phosphate | 1.4243 | 1.3117 | 0.6640 | 0.6000 |
| glycerate | 1.0511 | 0.9169 | 1.0037 | 1.0282 |
| Glycerol.3.Phosphate | 0.8473 | 2.3793 | 0.3473 | 0.4261 |
| Glycerophosphocholine | 0.9958 | 0.7589 | 1.1372 | 1.1081 |
| glycine | 1.0560 | 0.7897 | 1.0733 | 1.0809 |
| GMP | 0.5419 | 2.5164 | 0.4384 | 0.5033 |
| GSH_Ellmans | 0.9929 | 0.9242 | 1.0543 | 1.0287 |
| GSSG | 0.8602 | 0.9308 | 1.1872 | 1.0218 |
| GTP | 0.9474 | 0.8962 | 1.0063 | 1.1502 |
| histidine | 1.0074 | 0.8594 | 1.0569 | 1.0763 |
| hypotaurine | 1.2618 | 1.0059 | 0.9766 | 0.7557 |
| IMP | 1.3230 | 1.8014 | 0.4772 | 0.3985 |
| isoleucine | 0.9589 | 0.9632 | 1.0523 | 1.0256 |
| lactic_acid | 1.2198 | 1.0045 | 0.9182 | 0.8574 |
| lysine | 1.0205 | 0.8837 | 1.0528 | 1.0430 |
| mannose | 0.9349 | 0.8818 | 1.0320 | 1.1513 |
| methionine | 0.9651 | 0.9413 | 1.0562 | 1.0374 |
| Methionine.sulfoxide | 0.9443 | 0.8551 | 1.0680 | 1.1326 |
| methylthioadenosine | 1.0133 | 0.7069 | 1.1289 | 1.1509 |
| myo.inositol | 0.8910 | 1.0580 | 1.0239 | 1.0271 |
| N.acetylglutamate | 1.2757 | 0.8517 | 0.9757 | 0.8969 |
| NAD. | 1.0304 | 0.8464 | 1.0629 | 1.0603 |
| NADH | 0.7937 | 1.4280 | 0.8794 | 0.8990 |
| NADP | 0.9193 | 1.0244 | 1.0449 | 1.0114 |
| NADPH | 0.8860 | 0.8037 | 1.1739 | 1.1364 |
| niacinamide | 1.1029 | 0.9575 | 1.0426 | 0.8970 |
| O.phosphoethanolamine | 0.5386 | 3.2072 | 0.1137 | 0.1406 |
| ornithine | 0.9267 | 0.8610 | 1.0899 | 1.1224 |
| palmitate | 1.3216 | 0.7082 | 0.8637 | 1.1065 |
| Pantothenate | 1.0349 | 0.6535 | 1.1745 | 1.1371 |
| phosphocholine | 0.9365 | 0.7504 | 1.1685 | 1.1447 |
| phosphocreatine | 0.7538 | 1.1257 | 1.0821 | 1.0383 |
| phosphoenolpyruvate | 1.6623 | 0.4143 | 1.0932 | 0.8303 |
| proline | 1.1065 | 0.9458 | 0.9722 | 0.9755 |
| propionylcarnitine | 1.1072 | 0.5251 | 1.2189 | 1.1488 |
| Pyridoxine | 1.0125 | 0.8679 | 1.0428 | 1.0767 |
| S.Adenosyl.L.Homocysteine | 1.0093 | 0.7569 | 1.0886 | 1.1452 |
| S.Adenosyl.L.methionine | 0.9885 | 0.8239 | 1.1132 | 1.0744 |
| sarcosine | 0.9073 | 0.9540 | 1.0517 | 1.0870 |
| Sedoheptulose.7.phosphate | 1.3713 | 1.7022 | 0.4747 | 0.4519 |
| serine | 0.8613 | 1.0460 | 0.9645 | 1.1282 |
| succinate | 0.7501 | 1.8840 | 0.6553 | 0.7106 |
| taurine | 1.0392 | 0.9490 | 1.0699 | 0.9419 |
| threonine | 0.9405 | 0.9140 | 1.1080 | 1.0375 |
| tryptophan | 0.9782 | 0.9388 | 1.0435 | 1.0394 |
| tyrosine | 0.9343 | 0.8830 | 1.0843 | 1.0985 |
| UDP | 0.8690 | 0.8998 | 0.9873 | 1.2439 |
| UDP.GlcNAc | 0.8695 | 0.4308 | 1.3551 | 1.3446 |
| UMP | 0.5597 | 1.7583 | 0.7092 | 0.9729 |
| Ureidosuccinic_acid | 0.0593 | 3.5725 | 0.0162 | 0.3520 |
| uric.acid | 0.9985 | 0.6246 | 1.1906 | 1.1864 |
| UTP | 1.0587 | 0.3672 | 1.2388 | 1.3352 |
Factors:
| F1 | Sample source:SEM leukemia cells | guideRNA:BCS | overexpression:AOX |
| F2 | Sample source:SEM leukemia cells | guideRNA:BCS | overexpression:RFP |
| F3 | Sample source:SEM leukemia cells | guideRNA:Vehicle | overexpression:AOX |
| F4 | Sample source:SEM leukemia cells | guideRNA:Vehicle | overexpression:RFP |
