Data for (Study ST000157)

(Analysis AN000448)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6
2 or 3-phosphoglycerate_13C_1 NA NA NA NA NA NA
2 or 3-phosphoglycerate_13C_2 NA NA NA NA NA NA
2 or 3-phosphoglycerate_13C_3 NA NA NA NA NA NA
2 or 3-phosphoglycerate_2PG/3PG NA NA NA NA NA NA
3-Glycerophosphate 1.1749 1.6248 1.1268 0.9494 0.4042 0.7163
3-Glycerophosphate_13C_1 NA NA 1.4031 NA NA 0.1939
3-Glycerophosphate_13C_2 NA NA 0.5925 1.2037 NA NA
3-Glycerophosphate_13C_3 NA NA 1.6574 NA 0.3426 NA
3-phosphoglyceraldehyde 1.4144 2.3912 0.5910 1.2932 0.6581 0.0979
3-phosphoglyceraldehyde_13C_1 NA NA NA 0.1640 1.8360 NA
3-phosphoglyceraldehyde_13C_2 1.1679 2.1793 0.9514 1.2400 0.3596 0.5352
3-phosphoglyceraldehyde_13C_3 NA NA NA NA NA NA
6-Phosphogluconate 1.1220 1.7787 0.7907 1.1487 0.9180 0.5802
6-Phosphogluconate_13C_1 NA 0.0277 NA 1.4862 NA NA
6-Phosphogluconate_13C_2 NA 0.9417 NA 1.0583 NA NA
6-Phosphogluconate_13C_3 NA NA NA NA NA NA
6-Phosphogluconate_13C_4 NA NA NA NA NA NA
6-Phosphogluconate_13C_5 NA NA NA NA NA NA
6-Phosphogluconate_13C_6 NA NA NA NA NA NA
Acetyl-CoA 1.1406 0.5505 1.4185 1.0477 0.4573 0.1095
Acetyl-CoA_13C_1 NA NA 1.0000 NA NA NA
Acetyl-CoA_13C_2 0.7290 NA NA 1.2710 NA NA
Adenosine diphosphate 1.6407 1.3822 1.0042 1.3602 0.3829 0.2623
Adenosine diphosphate_13C_1 0.4960 0.5259 1.8584 2.6834 0.1661 0.5551
Adenosine diphosphate_13C_2 0.2800 0.8109 1.0545 3.6665 0.1736 0.2668
Adenosine diphosphate_13C_3 0.4636 0.6054 1.3300 3.6772 0.0915 0.4931
Adenosine diphosphate_13C_4 0.1293 0.7731 0.6871 3.9530 NA 0.2822
Adenosine diphosphate_13C_5 NA NA 0.2108 1.7892 NA NA
Adenosine monophosphate 1.5147 1.7486 0.8327 1.0458 0.6371 0.3701
Adenosine monophosphate_13C_1 0.4720 0.5923 1.7192 2.2037 0.2874 0.9269
Adenosine monophosphate_13C_2 0.2949 1.3405 1.1242 3.3396 0.1134 0.8116
Adenosine monophosphate_13C_3 0.4275 0.9281 1.2333 3.0191 0.1997 0.9318
Adenosine monophosphate_13C_4 0.1698 1.3894 0.8114 4.1324 0.0353 0.4804
Adenosine monophosphate_13C_5 0.1113 0.5045 0.5711 3.9501 NA 0.2918
Adenosine triphosphate 1.5358 0.9931 1.2101 1.6482 0.3142 0.2639
Adenosine triphosphate_13C_1 0.4359 0.2385 1.3883 2.0023 0.0530 0.8430
Adenosine triphosphate_13C_2 0.1556 0.3031 1.0309 2.9170 NA NA
Adenosine triphosphate_13C_3 0.2451 0.1482 1.2659 3.3682 0.0527 0.3816
Adenosine triphosphate_13C_4 NA 0.1515 0.3951 3.1150 NA 0.0381
Adenosine triphosphate_13C_5 NA NA NA 1.0000 NA NA
Aspartate 1.1683 0.7352 1.5172 0.6770 0.7821 0.6959
Aspartate_13C_1 0.3687 0.1751 2.4939 0.6218 0.2649 0.8453
Aspartate_13C_2 0.5109 0.4186 2.3053 1.1430 0.1452 1.0882
Aspartate_13C_3 0.1955 0.0313 1.8846 1.2297 NA 0.3720
Aspartate_13C_4 NA NA NA NA NA NA
Citrate or Isocitrate 1.2840 0.8009 1.0557 0.6423 0.9565 0.9617
Citrate or Isocitrate_13C_1 0.9218 NA 1.2592 0.4314 1.3352 NA
Citrate or Isocitrate_13C_2 1.6735 0.8706 1.3172 1.4299 0.2094 0.2692
Citrate or Isocitrate_13C_3 0.3005 2.3448 0.6519 0.9603 0.0937 NA
Citrate or Isocitrate_13C_4 NA NA NA NA NA NA
Citrate or Isocitrate_13C_5 0.0370 NA 2.1455 NA 1.3790 1.0075
Citrate or Isocitrate_13C_6 0.5834 0.8001 1.0380 0.5936 1.5594 1.3496
Erythrose 4-phosphate 1.2954 2.4206 0.6547 1.2603 0.7231 0.2228
Erythrose 4-phosphate_13C_1 NA NA 1.2517 1.1888 0.5594 NA
Erythrose 4-phosphate_13C_2 0.3345 0.9690 0.1153 2.7484 0.0002 NA
Erythrose 4-phosphate_13C_3 NA NA NA 1.0000 NA NA
Erythrose 4-phosphate_13C_4 NA NA NA NA 1.0000 NA
Fructose 1,6-bisphosphate 1.0063 3.1180 0.9514 0.9932 0.4759 0.1731
Fructose 1,6-bisphosphate_13C_1 NA 1.4882 0.8232 0.8654 NA NA
Fructose 1,6-bisphosphate_13C_2 0.3158 3.2843 0.3724 2.7694 0.0467 NA
Fructose 1,6-bisphosphate_13C_3 NA 0.2388 0.0923 2.2540 0.1609 NA
Fructose 1,6-bisphosphate_13C_4 0.0187 1.0744 0.0339 1.8993 NA NA
Fructose 1,6-bisphosphate_13C_5 NA NA NA NA NA NA
Fructose 1,6-bisphosphate_13C_6 NA 1.2097 NA 0.5806 NA NA
Glucose 6-phosphate or fructose-6-phosphate 1.6520 2.6678 0.5130 0.6558 0.7396 0.1579
Glucose 6-phosphate or fructose-6-phosphate_13C_1 0.5769 2.1635 0.8677 2.1116 0.4897 0.6009
Glucose 6-phosphate or fructose-6-phosphate_13C_2 0.8472 2.2209 0.3469 3.7368 0.1944 0.2416
Glucose 6-phosphate or fructose-6-phosphate_13C_3 0.0980 1.7211 0.2612 3.0738 NA 0.3326
Glucose 6-phosphate or fructose-6-phosphate_13C_4 0.4183 2.2115 0.2633 3.6857 0.1567 0.1953
Glucose 6-phosphate or fructose-6-phosphate_13C_5 NA 0.0614 0.0004 1.9691 NA NA
Glucose 6-phosphate or fructose-6-phosphate_13C_6 0.2927 0.7069 2.3797 0.9138 NA NA
Glutamate 1.4517 1.5836 0.8695 1.1286 0.7020 0.3949
Glutamate_13C_1 0.7554 0.4630 1.7960 1.7846 0.2945 0.5607
Glutamate_13C_2 0.9506 1.0852 1.5476 1.8472 0.2433 0.4709
Glutamate_13C_3 0.1252 0.1673 1.7749 2.1813 NA 0.4138
Glutamate_13C_4 NA 0.1834 1.0915 2.0207 NA 0.2046
Glutamate_13C_5 NA NA NA NA NA NA
Lactate NA NA NA NA NA NA
Lactate_13C_1 NA NA NA NA NA NA
Lactate_13C_2 NA NA NA NA NA NA
Lactate_13C_3 NA NA NA NA NA NA
Malate 1.2630 1.6559 1.0990 1.0419 0.6266 0.4256
Malate_13C_1 0.4019 0.4201 2.1783 1.5844 0.1452 0.6899
Malate_13C_2 0.6641 1.0684 1.8337 1.9306 0.2003 0.4700
Malate_13C_3 0.2609 0.2518 1.5584 1.5304 NA 0.0965
Malate_13C_4 0.5290 1.2901 1.1777 2.5737 0.4885 0.6601
Malonyl-CoA NA NA NA NA NA NA
Malonyl-CoA_13C_1 NA NA NA NA NA NA
Malonyl-CoA_13C_2 NA NA NA NA NA NA
Malonyl-CoA_13C_3 NA NA NA NA NA NA
Nicotinamide Adenine Dinucleotide oxidized 1.9341 0.4751 1.9911 0.6809 0.0685 0.3547
Nicotinamide Adenine Dinucleotide oxidized_13C_1 NA NA 1.0000 NA NA NA
Nicotinamide Adenine Dinucleotide oxidized_13C_2 NA NA 1.0000 NA NA NA
Nicotinamide Adenine Dinucleotide oxidized_13C_3 NA NA 1.0000 NA NA NA
Nicotinamide Adenine Dinucleotide oxidized_13C_4 NA NA NA NA NA NA
Nicotinamide Adenine Dinucleotide oxidized_13C_5 NA NA NA NA NA NA
Nicotinamide Adenine Dinucleotide reduced 1.1697 0.8806 1.7796 0.9869 0.1098 0.1976
Nicotinamide Adenine Dinucleotide reduced_13C_1 NA NA 1.1641 NA NA 0.6718
Nicotinamide Adenine Dinucleotide reduced_13C_2 NA NA 0.0674 1.9326 NA NA
Nicotinamide Adenine Dinucleotide reduced_13C_3 1.1895 NA 1.1918 0.6186 NA NA
Nicotinamide Adenine Dinucleotide reduced_13C_4 NA NA 0.5629 1.4371 NA NA
Nicotinamide Adenine Dinucleotide reduced_13C_5 NA NA NA NA NA NA
Phosphoenolpyruvate NA NA NA NA NA NA
Phosphoenolpyruvate_13C_1 NA NA NA NA NA NA
Phosphoenolpyruvate_13C_2 NA NA NA NA NA NA
Phosphoenolpyruvate_13C_3 NA NA NA NA NA NA
Ribose-5-phosphate or xylulose 5-phosphate 1.5320 1.8938 0.9636 0.7069 0.6957 0.2429
Ribose-5-phosphate or xylulose 5-phosphate_13C_1 0.5819 0.8036 1.8580 1.3782 0.3050 0.6332
Ribose-5-phosphate or xylulose 5-phosphate_13C_2 0.5095 1.8841 1.2388 2.3951 0.1909 0.4379
Ribose-5-phosphate or xylulose 5-phosphate_13C_3 0.3575 0.9392 1.5979 1.9901 0.3211 0.4993
Ribose-5-phosphate or xylulose 5-phosphate_13C_4 0.1334 1.5327 1.0781 2.8859 0.0658 0.1921
Ribose-5-phosphate or xylulose 5-phosphate_13C_5 NA NA NA NA NA NA
Sedoheptulose 7-phosphate 1.4985 1.9817 0.8484 0.7309 0.7981 0.2644
Sedoheptulose 7-phosphate_13C_1 0.6908 1.0167 1.8352 0.7518 0.3914 0.7881
Sedoheptulose 7-phosphate_13C_2 0.1086 1.3624 1.1497 3.0346 0.0573 0.1667
Sedoheptulose 7-phosphate_13C_3 0.0583 0.9144 0.9981 2.3352 NA 0.1813
Sedoheptulose 7-phosphate_13C_4 0.1788 1.0058 0.2039 3.2425 NA 0.3690
Sedoheptulose 7-phosphate_13C_5 0.1766 3.0646 0.3272 0.5186 0.0025 NA
Sedoheptulose 7-phosphate_13C_6 NA 2.1603 0.2006 0.5736 0.7047 NA
Sedoheptulose 7-phosphate_13C_7 NA 1.0000 NA NA NA NA
Sucrose 1.4567 1.8331 0.7188 1.2121 0.7389 0.3303
Sucrose_13C_1 0.8197 NA 1.1673 1.1483 0.0834 1.4787
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Factors:

F1Cell type:AMPKαfl/fl | Labeling time, min:5 | 1,2-13C2-labeled glucose concentration, g/L:0.2
F2Cell type:AMPKαfl/fl | Labeling time, min:5 | 1,2-13C2-labeled glucose concentration, g/L:2
F3Cell type:AMPKαfl/fl | Labeling time, min:60 | 1,2-13C2-labeled glucose concentration, g/L:0.2
F4Cell type:AMPKαfl/fl | Labeling time, min:60 | 1,2-13C2-labeled glucose concentration, g/L:2
F5Cell type:AMPKαΔ/Δ | Labeling time, min:5 | 1,2-13C2-labeled glucose concentration, g/L:0.2
F6Cell type:AMPKαΔ/Δ | Labeling time, min:60 | 1,2-13C2-labeled glucose concentration, g/L:0.2
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