Data for (Study ST000308)

(Analysis AN000488)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7
2PG/3PG 0.7867 0.6213 1.4722 0.7214 1.4901 0.7667 1.0466
2PG/3PG_13C_1 NA NA NA NA NA NA NA
2PG/3PG_13C_2 NA NA NA 0.2904 1.6192 0.7626 1.3279
2PG/3PG_13C_3 NA NA NA NA NA NA NA
6PG 0.7802 1.6767 1.6472 0.9477 1.2825 0.5215 0.8110
6PG_13C_1 0.4262 1.0290 0.8757 0.6838 1.1829 0.9961 1.7842
6PG_13C_2 0.0247 0.0261 0.0029 0.4528 1.1632 1.4297 2.5866
6PG_13C_3 0.2036 0.1315 0.3399 0.4522 0.6600 1.5471 2.8666
6PG_13C_4 0.3242 0.3107 0.3853 0.5005 0.7887 1.2714 2.1582
6PG_13C_5 NA NA NA NA NA NA NA
6PG_13C_6 NA NA NA NA NA NA NA
aCoA 0.7090 1.7634 1.5902 0.5703 1.4935 0.5970 0.9823
aCoA_13C_1 NA NA 1.0000 NA NA NA NA
aCoA_13C_2 NA NA NA NA 0.9840 NA 1.0320
ADP 0.7513 1.8434 1.4201 0.9301 1.1856 0.7094 0.8624
ADP_13C_1 0.0959 NA NA 0.2923 0.3429 1.3838 2.2823
ADP_13C_2 0.0186 NA 0.0332 0.2505 0.5956 1.5447 2.9129
ADP_13C_3 0.0538 0.0186 0.0687 0.4261 0.6212 1.6425 3.2044
ADP_13C_4 0.0322 0.0089 0.0349 0.2209 0.5521 1.6315 3.2144
ADP_13C_5 NA 0.0949 0.0459 0.0156 0.3315 1.1204 2.2731
AMP 0.9848 2.0780 1.6598 0.8811 0.8771 0.6889 0.7690
AMP_13C_1 NA NA NA 0.2168 0.2268 1.4108 2.1456
AMP_13C_2 0.0114 0.0218 0.0661 0.2549 0.5408 1.7777 3.0343
AMP_13C_3 0.0461 0.0240 0.0615 0.4393 0.4931 1.8285 3.1439
AMP_13C_4 0.0384 0.0026 0.0413 0.2138 0.4412 1.7748 3.1828
AMP_13C_5 NA 0.1449 0.2254 0.2689 0.2863 1.6262 2.3422
ASP 0.8027 1.2527 1.3669 0.8944 0.9953 0.9156 1.0631
ASP_13C_1 0.0602 0.0704 NA 0.0662 0.2336 1.6464 2.6769
ASP_13C_2 0.0084 0.0008 0.0083 0.2602 0.6252 1.7380 2.3708
ASP_13C_3 NA 0.1135 0.4441 0.2428 0.3699 1.3715 1.9919
ASP_13C_4 NA 0.0340 NA 0.4366 NA 0.2738 2.2360
ATP 0.6497 0.8945 1.2331 1.0538 1.4125 0.8166 0.9471
ATP_13C_1 0.0754 NA 0.1046 0.3763 0.5164 1.6020 2.7284
ATP_13C_2 0.0385 NA 0.0436 0.2531 0.7043 1.6579 2.9837
ATP_13C_3 0.0512 NA 0.0464 0.3385 0.6631 1.3916 2.8750
ATP_13C_4 0.0358 NA 0.0450 0.2281 0.5456 1.4779 2.7095
ATP_13C_5 NA NA NA NA 0.1300 0.6490 1.6410
CIT/ICIT 0.7274 1.1649 1.6650 0.8248 1.3519 0.6195 0.9782
CIT/ICIT_13C_1 0.1474 0.0891 0.2140 1.3754 0.8697 1.9252 1.2257
CIT/ICIT_13C_2 0.0308 0.0247 0.0446 0.8798 1.9054 1.3317 1.8143
CIT/ICIT_13C_3 0.0665 0.7542 0.2159 0.3436 0.5912 1.6194 2.9840
CIT/ICIT_13C_4 NA NA NA NA 0.6433 0.9011 1.4555
CIT/ICIT_13C_5 NA 2.2797 0.6028 0.5389 0.7220 1.0078 1.2622
CIT/ICIT_13C_6 0.8439 1.4888 0.8197 0.8562 1.0463 1.0531 1.1578
E4P 1.2151 1.5725 1.1142 0.8436 1.0047 0.9863 0.6833
E4P_13C_1 NA NA NA NA NA 1.0000 NA
E4P_13C_2 0.3333 NA 0.3774 1.2043 1.2073 1.6763 0.9939
E4P_13C_3 0.6016 0.5355 1.5248 0.5649 1.3263 0.6827 1.6295
E4P_13C_4 NA NA 0.4768 NA 0.8950 NA 1.3666
FBP 1.5393 1.9030 1.8268 0.7401 0.9651 0.4907 0.4126
FBP_13C_1 0.1633 0.0816 0.1199 1.0167 1.9229 1.5692 0.9420
FBP_13C_2 0.1758 0.0959 0.1705 0.6269 2.7494 1.0615 1.2407
FBP_13C_3 0.0025 NA NA 0.3483 1.7725 1.3151 0.8965
FBP_13C_4 0.1576 NA 0.1343 0.4202 2.3205 0.9280 1.1815
FBP_13C_5 NA NA NA NA NA NA NA
FBP_13C_6 NA NA NA NA NA NA NA
G3P 1.4403 0.8452 1.6787 1.0106 0.8028 0.7709 0.5745
G3P_13C_1 NA NA NA 1.0661 0.6789 1.3879 0.8671
G3P_13C_2 0.0270 0.0168 0.0038 1.3322 1.3341 1.3719 1.2702
G3P_13C_3 NA NA NA NA NA NA NA
G6P/F6P 1.8892 1.8571 1.2683 0.8299 0.7238 0.7003 0.3921
G6P/F6P_13C_1 0.2415 0.2632 0.1534 1.2970 0.9764 2.3036 0.9915
G6P/F6P_13C_2 0.0329 0.0310 0.0603 0.9577 1.6580 1.9008 1.3999
G6P/F6P_13C_3 NA NA NA 0.6233 0.6831 1.7361 0.9575
G6P/F6P_13C_4 NA NA 0.0945 0.5388 1.0587 1.4535 1.2508
G6P/F6P_13C_5 NA NA 0.0036 0.4659 0.9648 2.1910 0.5480
G6P/F6P_13C_6 NA NA NA NA NA 1.0000 NA
GI_OH3P 0.7643 1.4728 2.4506 0.4040 1.5171 0.3687 0.8212
GI_OH3P_13C_1 0.0784 0.2735 0.3253 0.7655 2.0091 1.0535 1.4783
GI_OH3P_13C_2 0.1514 NA 0.2052 0.5843 2.0486 0.8455 1.6172
GI_OH3P_13C_3 0.0040 0.1085 NA 0.2122 1.8081 0.9568 1.3751
GLU 0.6141 0.7537 1.3025 0.9672 1.2737 0.8201 1.2053
GLU_13C_1 0.0617 NA NA 0.2998 0.2125 1.5528 2.2979
GLU_13C_2 0.0013 NA NA 0.4723 0.8579 1.3362 1.9993
GLU_13C_3 0.0004 0.0822 0.0167 0.0974 0.2845 1.8046 2.7804
GLU_13C_4 0.0096 0.0159 NA 0.0495 0.3020 1.5578 2.7490
GLU_13C_5 NA 1.8506 NA NA 0.0685 0.3256 1.2518
LAC 1.0070 1.7615 1.5839 0.7894 1.1104 0.6799 0.7701
LAC_13C_1 NA NA NA NA NA NA NA
LAC_13C_2 NA NA NA 0.4935 1.4084 0.7505 1.3476
LAC_13C_3 NA NA NA NA NA NA NA
MAL 0.8762 1.1125 1.3440 1.0527 1.0900 0.8006 0.9137
MAL_13C_1 0.0280 0.0208 0.0736 0.2292 0.4809 1.9276 2.6455
MAL_13C_2 0.0398 0.0231 0.0407 0.4655 0.8371 1.8535 2.4494
MAL_13C_3 0.2220 0.2243 0.1758 0.3575 0.4188 2.1460 2.6637
MAL_13C_4 NA 0.4001 0.1267 0.4301 0.4366 1.1416 2.1051
mCoA NA NA NA NA NA NA NA
mCoA_13C_1 NA NA NA NA NA NA NA
mCoA_13C_2 NA NA NA NA NA NA NA
mCoA_13C_3 NA NA NA NA NA NA NA
NAD 0.8263 0.4489 1.2420 1.0280 1.2476 0.8117 1.1087
NAD_13C_1 0.0040 0.2905 0.6262 0.2550 0.6823 0.8280 2.6795
NAD_13C_2 NA NA NA NA 0.3138 0.5389 1.7648
NAD_13C_3 NA NA NA 0.0096 0.2049 0.2972 2.8280
NAD_13C_4 NA NA 0.0450 0.0172 0.1943 0.6450 2.5380
NAD_13C_5 NA NA 0.2671 0.5298 0.0461 0.5481 1.8696
NADH 0.8164 0.7260 0.9210 1.1821 1.2688 1.0064 0.8703
NADH_13C_1 0.1576 0.1759 0.1524 0.6702 0.7881 1.5353 2.4061
NADH_13C_2 NA NA 0.3066 0.1916 0.6047 1.0489 2.3860
NADH_13C_3 0.0294 NA 0.0485 NA 0.6629 0.5518 2.4260
NADH_13C_4 NA NA 0.0924 0.0705 0.4225 0.9006 2.0967
NADH_13C_5 NA NA NA NA NA NA NA
PEP NA NA NA NA NA NA NA
PEP_13C_1 NA NA NA NA NA NA NA
PEP_13C_2 NA NA NA NA NA NA NA
PEP_13C_3 NA NA NA NA NA NA NA
R5P/X5P 1.3290 2.0129 1.4755 0.7127 1.0116 0.5950 0.6971
R5P/X5P_13C_1 0.1126 0.0684 0.3054 0.8597 1.3670 1.6339 1.8004
R5P/X5P_13C_2 0.1136 0.0499 0.1014 0.6968 1.4120 1.5640 1.8299
R5P/X5P_13C_3 NA NA 0.0128 0.4664 1.0806 1.1433 1.6388
R5P/X5P_13C_4 0.0117 NA 0.0766 0.2572 0.7362 1.5918 2.1338
R5P/X5P_13C_5 NA NA 0.5311 0.3824 NA 0.9958 1.3649
S7P 1.2511 1.5663 1.3863 0.8848 0.9676 0.6585 0.7917
S7P_13C_1 0.1058 0.1757 0.0868 1.2387 1.2322 1.8291 1.1735
S7P_13C_2 NA NA NA 0.6726 0.8290 1.3184 1.1799
S7P_13C_3 0.0295 NA 0.0043 0.7809 1.1194 1.8105 1.5916
S7P_13C_4 0.0315 0.1773 0.1058 0.6478 1.1516 1.7871 1.9296
S7P_13C_5 1.0997 1.0670 1.4104 0.8016 1.3057 0.7120 0.7850
S7P_13C_6 0.1476 0.1355 0.2338 1.5384 2.3544 0.5245 0.9786
S7P_13C_7 0.2005 NA NA 1.0431 1.7242 0.6696 1.0006
SUC 0.7542 1.3955 1.4183 0.8688 1.1308 0.7857 1.0497
SUC_13C_1 0.2852 0.1447 0.6058 0.6383 1.2659 1.7335 1.6250
SUC_13C_2 NA NA 0.6206 0.4192 0.8456 1.5090 1.4930
SUC_13C_3 NA NA NA NA NA 0.5792 2.2624
SUC_13C_4 NA NA NA 0.3093 NA 1.6907 NA
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Factors:

F1Timepoint:0 | Type:KO | Treatment:yes
F2Timepoint:0 | Type:WT | Treatment:no
F3Timepoint:0 | Type:WT | Treatment:yes
F4Timepoint:5 | Type:KO | Treatment:yes
F5Timepoint:5 | Type:WT | Treatment:yes
F6Timepoint:60 | Type:KO | Treatment:yes
F7Timepoint:60 | Type:WT | Treatment:yes
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