Data for (Study ST000509)

(Analysis AN000780)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8F9F10F11
10-Formyltetrahydrofolate 0.7036 0.8999 0.8931 1.5698 1.0612 0.9231 0.8300 1.1501 0.8196 1.0304 1.1054
1-4-beta-D-Xylan 1.1699 0.9855 0.9570 0.8311 1.0164 1.2897 0.8792 0.7306 1.0804 0.9166 1.0999
1-(5Z_8Z_11Z_14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine 1.0891 0.9300 1.1806 1.1009 0.9426 0.9970 NA 1.2621 0.9212 0.4904 0.8451
1-hexadecanoyl-sn-glycero-3-phosphoethanolamine 0.6942 1.7954 1.3993 0.8681 0.9330 1.0993 NA 1.0320 0.7609 0.7228 0.6151
1-octadecanoyl-sn-glycero-3-phosphoethanolamine 1.0754 1.2307 1.2205 0.9253 1.0788 0.9393 NA 1.1959 0.7968 0.8330 0.7729
21-Hydroxypregnenolone 0.8046 1.5190 1.1473 1.2962 0.6316 0.4530 NA 1.2749 1.6115 0.5347 0.4597
2--3--Cyclic CMP 0.7321 1.4742 1.3076 0.7285 0.6647 0.9592 0.7600 1.2676 1.4413 0.9818 0.8093
2-(5Z_8Z_11Z_14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine 0.9770 1.1353 1.1822 0.9979 0.8656 0.7801 NA 1.2367 1.1297 0.7078 0.9104
2-Methyleneglutarate 1.0961 0.7861 0.9966 0.9391 1.1506 0.8986 0.9934 1.1057 0.8996 0.9098 1.2129
2-Oxo-7-methylthioheptanoic acid 0.9228 1.3543 1.4003 1.0555 0.8703 0.7475 1.1044 0.7737 0.7954 1.1416 0.9163
2-tetradecanoyl-sn-glycero-3-phosphocholine 0.6471 2.5507 1.7175 0.8265 0.7654 1.3033 0.2969 0.8913 0.7968 0.5771 0.5707
3alpha-7alpha-12alpha-Trihydroxy-5beta-cholanate 0.9365 0.9068 1.1949 0.8332 0.9462 0.9285 1.0226 1.0715 1.2014 1.0996 0.8877
3-Methyleneoxindole 1.0636 1.0738 0.9954 0.9949 1.1106 0.9310 0.8813 1.0245 0.9838 0.9624 1.0003
4-Acetamidobutanoate 0.9160 0.7328 1.8705 1.1253 1.0263 0.9774 0.7907 1.0051 0.9448 0.9870 0.8584
4-Aminobenzoate 0.7536 1.5038 0.9660 0.9487 0.8468 1.6182 0.7016 0.8571 1.3563 0.7651 0.6810
5-10-Methenyltetrahydrofolate 0.9079 0.3185 0.4623 0.3702 0.7724 0.6681 1.7356 1.6012 1.3392 1.6795 0.9750
5-Hydroxyindoleacetate 1.3438 0.1334 0.2273 NA NA 0.9750 1.9707 NA NA 0.8517 1.4475
5-Hydroxyisourate 1.1760 0.8376 0.7738 0.8675 0.9164 1.0630 1.1229 0.8905 1.2914 1.0287 0.9450
(5-L-Glutamyl)-L-glutamine 1.2875 0.9216 0.9986 0.9712 0.9211 1.0274 0.8888 0.9350 1.0313 1.1827 0.9258
(5-L-Glutamyl)-peptide 0.1497 0.4454 0.0584 0.1053 0.4011 1.7962 0.6506 0.2227 4.5723 0.2358 0.2412
5-L-Glutamyl-taurine 1.4819 1.0285 1.3224 1.6347 1.4175 1.0481 0.1287 0.5282 1.1761 0.3114 1.0371
5-Oxoproline 1.2813 0.8969 0.8635 0.9997 1.0234 1.0162 0.9298 0.9182 1.1476 0.9312 0.9874
5--Phosphoribosyl-N-formylglycinamide 0.4352 2.6833 2.5639 0.7240 0.7234 1.0423 0.1081 0.8117 0.7639 0.4190 0.2910
Adenine 1.1020 0.8690 0.6618 1.1262 1.0673 1.1875 0.8754 1.1015 1.0018 0.9906 1.0008
Adenosine 1.1871 0.5941 0.4180 1.1455 1.0032 1.1488 0.9482 1.2407 1.0566 1.2016 1.0199
Adenylyl sulfate 0.7152 0.8710 1.2137 0.3108 1.0859 1.0462 1.1871 0.6952 1.3884 1.0551 0.9716
alanine 0.9082 1.1078 0.9268 0.8993 0.9079 1.2541 0.8950 0.9158 1.1613 0.9934 0.9898
Allantoate 1.0170 1.2931 1.4228 1.0058 0.9751 1.1308 0.7199 0.7895 1.0006 0.9095 0.8689
alpha-D-Glucosamine 1-phosphate 1.1431 1.8965 1.0963 0.5011 0.7330 1.3315 0.5267 0.6187 2.1455 0.2681 0.6917
alpha-N-Peptidyl-L-glutamate 1.0414 0.9686 1.0211 0.9491 0.9471 0.8979 0.8797 1.1868 1.3104 1.0066 0.8448
AMP 1.1515 1.1496 1.0951 1.0189 1.0031 1.0594 0.8716 0.9430 0.9893 0.9197 0.8866
arginine 0.6982 1.4650 1.2944 1.1094 0.8591 0.8587 0.8914 1.2766 1.0851 0.8497 0.7494
asparagine 0.8479 1.2691 0.9925 0.8620 0.9788 1.0702 0.8902 1.0541 1.1462 0.9338 0.9427
aspartate 1.0335 0.8883 0.8610 0.9321 1.0130 0.9990 0.8267 1.2260 1.0861 1.2974 0.8967
Catecholamine 0.6547 0.6440 0.6264 0.5637 0.5380 2.1030 0.8085 1.4667 1.2650 1.3299 1.0229
cis-p-Coumarate 1.0568 0.9849 0.9668 0.9258 1.0908 1.0540 0.9181 1.1085 0.8567 1.1112 0.9830
Creatine 0.7910 0.4754 0.5735 0.6700 1.0427 1.3449 1.2321 1.0001 1.2779 0.8727 1.4018
Creatinine 1.0557 0.8935 0.8722 0.8950 0.9983 1.1312 0.9856 1.0316 1.0641 1.0316 1.0197
Cys-Gly 0.9511 1.1946 1.1064 1.0231 1.0297 1.1008 0.7798 0.9863 1.0368 0.8920 0.9491
Cystathionine 0.8394 1.3602 0.9758 0.7898 0.8290 0.8560 1.0395 0.9356 1.1549 1.2998 0.8879
cysteine 0.7798 1.1240 1.1173 0.9826 0.8707 0.9037 1.0365 1.1771 1.1732 1.0425 0.8261
cystine 0.7799 0.5668 1.1862 0.7921 1.1859 1.4577 1.1119 1.1123 0.8742 0.7592 1.1291
Cytidine 0.8129 1.3428 1.1997 0.8144 0.9143 1.1320 0.7279 1.1528 1.3759 0.8282 0.7738
Decanoic acid (caprate) 0.9544 0.9080 0.9582 1.0054 0.9742 1.0372 1.0870 1.0144 1.0125 1.0968 0.9355
Dethiobiotin 0.8349 0.8064 0.8338 0.8425 0.6670 1.3813 0.8007 1.3149 1.2615 1.4157 0.9102
D-Glucosamine 1.0134 0.5914 0.8812 0.8876 0.9317 0.9086 1.4983 1.1802 0.8674 1.1442 1.0428
Dihydrofolate 1.5249 0.9894 0.3567 0.8029 1.4199 1.0692 1.0774 0.9163 0.8769 0.6198 1.1928
D-O-Phosphoserine 1.3078 0.7975 1.0831 0.6413 1.2201 0.8654 1.0497 0.8961 1.4724 0.6465 0.8885
D-Ribitol 5-phosphate 0.9356 0.8822 0.9572 0.7530 0.8665 1.5180 0.9431 0.8868 1.1262 0.8770 1.1861
Ectoine 0.8183 0.7959 0.7938 0.8766 0.6422 1.0856 0.8669 1.1784 1.5180 1.2577 1.0995
Folate 0.5789 1.3764 2.2735 0.9038 1.0715 1.3238 0.7640 0.9357 0.2822 0.9021 0.9351
gamma-Glutamyl-gamma-aminobutyrate 0.9049 1.0071 0.9024 0.9338 1.0223 0.9985 0.9336 1.2546 1.2168 1.1475 0.7136
gamma-Glutamyl-Se-methylselenocysteine 0.8148 0.9746 0.9618 0.9257 0.8575 1.1750 0.8561 1.1025 1.1241 1.0560 1.1335
gamma-L-Glutamyl-D-alanine 0.9024 0.9358 0.8785 1.1288 0.7363 1.3727 0.9206 0.8217 1.3389 0.9871 0.9153
gamma-L-Glutamyl-L-cysteine 0.8098 1.1587 1.3009 0.9647 0.8531 1.0537 0.8581 1.1772 1.1897 0.8468 0.8873
gamma-L-Glutamylputrescine 1.0907 1.1440 0.9778 1.5313 1.2700 0.7398 0.6930 0.5085 1.0940 0.5794 1.2296
glutamate 1.1158 0.8048 0.8606 0.8689 1.0822 0.8155 0.9981 1.1203 1.3641 0.9152 0.9872
glutamine 1.2736 0.9204 0.8497 0.9885 0.9634 1.0083 0.9147 0.9371 1.1701 0.9535 1.0194
Glutathione 0.9379 1.1806 1.1076 1.0063 1.0004 1.1218 0.7932 0.9898 1.0513 0.9044 0.9539
Glutathione disulfide 1.1746 0.7534 1.0282 0.8258 1.0593 0.8327 1.0872 1.1582 0.9517 1.0546 1.1057
glycine 1.0780 1.0429 0.9270 0.8922 1.0266 0.9306 1.0093 0.9870 1.1003 1.0237 0.9613
Glycochenodeoxycholate 0.7206 1.1520 0.4035 0.8111 1.8164 0.4820 1.2902 2.1855 0.2413 0.9096 0.8972
Glycocholate 1.1006 1.1452 0.7698 0.9736 1.9597 0.8983 0.2643 1.5517 0.3519 0.5219 0.9567
Glycodeoxycholate 1.1606 0.9084 0.4287 0.4677 2.1093 1.2580 0.0793 1.9872 0.4705 0.5005 0.7440
Guanidinoacetate 1.0690 0.7791 1.1674 1.0006 0.9828 0.6534 0.9080 1.1578 0.9023 1.4693 1.0256
Guanine 1.2787 0.7213 0.4228 1.3002 1.0975 0.8067 0.8738 0.9981 0.9945 1.0782 1.3125
Guanosine 1.2788 0.6611 0.4493 1.2487 1.1131 0.6842 0.9407 1.0457 1.0346 1.1470 1.2782
Heptanoic acid 0.8162 0.8860 0.9656 0.9676 1.2306 1.5762 0.9252 0.9933 0.9081 0.7169 0.9638
histidine 0.9643 1.2117 1.0271 1.0203 0.9825 1.3255 0.9083 0.8621 0.7917 0.9386 1.0017
Homocarnosine 0.5360 0.4475 0.5262 0.4311 0.4961 2.0032 1.3728 0.8333 1.4408 0.6746 1.7962
Homomethionine 1.3603 0.7602 1.0770 0.9693 1.1006 1.3724 0.9050 1.0323 1.0899 0.8517 0.6301
Hydroxyacetone phosphate 1.1762 0.8811 1.1268 1.0155 1.0539 0.9126 0.9352 1.0151 0.9809 0.8719 1.0837
hydroxy-dodecanedioic acid 0.5804 1.2534 1.3043 0.6933 0.6993 1.5166 1.0376 1.2306 1.2665 0.6990 0.7844
Hypotaurine 0.5968 2.2971 1.8945 1.1585 0.6992 0.9517 0.6167 0.6165 1.3346 0.5424 0.4862
Hypoxanthine 1.0912 0.6486 0.4823 1.1293 1.0107 0.7740 0.9880 1.0214 0.9710 1.0527 1.6299
Icosatetraenoic acid 0.9905 1.1782 0.5149 0.7332 0.9268 1.5022 NA 0.7548 1.2972 0.5723 1.1384
Indole 1.0162 0.9619 0.9935 1.0713 1.0854 0.9504 0.9246 1.0445 0.9205 0.9553 1.0842
Inosine 0.9710 0.6118 0.4211 1.1222 0.9879 0.7725 0.9918 1.0851 1.0444 1.0825 1.6669
isoleucine 1.0637 1.0762 1.0742 1.0385 1.0634 1.0605 0.7656 0.9517 0.9225 0.8549 1.1637
kynurenine 0.9116 0.6446 0.4414 0.9550 0.9369 0.6641 1.1624 1.6142 1.0192 1.4513 1.1407
L-2-Aminoadipate 1.1040 1.0290 0.9642 0.9362 0.9992 0.7848 1.0958 1.1428 0.9397 0.9499 1.0748
L-Arabinose 1.1544 0.9237 0.6922 0.7286 0.9649 1.2421 0.9392 1.1226 1.1791 1.1201 0.9253
L-Carnitine 0.9276 0.8779 0.8794 0.8799 0.8448 0.6814 1.1607 0.9770 1.3398 1.2195 1.0830
L-Citrulline 1.0976 0.9178 1.0172 0.8585 1.2530 0.8441 1.0486 0.8864 0.8124 1.0597 1.1516
leucine 0.9422 1.0047 0.9758 0.9128 0.9689 0.9716 1.0059 1.1900 1.0489 1.0924 0.9198
L-Homocitrulline 0.5478 1.2317 1.6766 0.7237 0.4990 1.6906 0.8224 1.0339 1.3284 0.7754 0.8269
L-Homocysteine 0.9773 1.1361 1.1986 0.8727 1.0174 0.9714 0.8514 1.0217 1.4830 0.7663 0.7277
L-Methionine S-oxide 0.8174 1.3335 0.9275 0.8340 0.7050 2.0954 0.7484 0.8224 1.2380 0.8268 0.6890
L-Noradrenaline 0.8139 0.9247 0.8941 1.0107 0.9695 0.7799 0.9348 0.9877 1.3641 1.1983 1.0066
L-Selenomethionine NA NA 0.9402 0.7498 0.2054 0.9264 0.9490 1.5481 1.1106 1.1358 0.4439
lysine 0.8812 1.6283 1.1115 1.0393 0.8244 1.1405 0.7675 1.0575 0.9854 0.8539 0.8376
Maleamate 1.0244 0.9136 0.8754 0.9355 1.0349 0.9927 0.8179 1.2302 1.0701 1.2841 0.8856
methionine 1.1888 0.9271 0.6618 0.7304 0.9774 1.1529 0.9191 1.1251 1.2304 1.1469 0.9249
N-(11Z-eicosaenoyl)-ethanolamine 0.5175 0.9905 1.1466 0.8376 0.2368 3.9041 0.2565 0.6888 1.2827 0.4518 0.3399
N5-Methyl-L-glutamine 1.2253 1.1112 1.0029 0.9353 0.9725 1.8039 0.8886 0.6885 0.7884 0.7810 0.8798
N6-Methyl-L-lysine 1.0037 1.8219 2.7439 1.4121 0.9580 0.5440 0.3196 0.4212 0.8906 0.3171 0.9735
N-(9Z-hexadecenoyl)-ethanolamine 1.5128 1.1819 1.1511 0.8947 1.2601 1.1025 0.4555 1.1837 0.8639 0.8167 0.8589
N-Acetyl-L-citrulline 0.8601 0.8777 0.7688 1.4791 0.9149 0.9521 0.8697 0.8647 1.3498 1.0445 0.9086
N-Acetylmethionine 1.1494 1.0292 1.3692 1.2180 1.0839 0.8760 0.8202 0.9669 0.8689 0.9191 0.8681
N-Acetylneuraminate 1.0722 0.9527 0.9061 0.8820 0.8341 0.7786 0.9553 1.1209 1.1511 1.3652 1.0113
N-Acetylornithine 0.9047 1.2424 1.1186 0.7382 1.2415 1.4259 0.7355 1.5001 0.6308 0.8236 0.8514
N-Acyl-D-mannosaminolactone 0.9859 0.6706 1.3177 0.8524 1.8488 0.5450 0.8338 0.9077 0.8578 0.7212 1.3278
NAD+ 1.0090 0.9652 1.0899 1.0181 1.0252 1.0724 1.1017 0.8324 1.0823 0.9767 0.8096
NADH 1.0091 0.9651 1.0924 1.0184 1.0126 1.0722 1.1065 0.8247 1.0932 0.9810 0.8064
N-Carbamyl-L-glutamate 1.3712 0.4443 2.6864 0.4613 1.1698 0.3249 1.5907 1.1113 0.4109 0.9788 0.8749
Nicotinamide 1.1827 0.6602 0.5631 0.9603 0.9201 0.8063 1.0450 1.2201 1.0016 1.3438 1.2472
N-(L-Arginino)succinate 1.1115 0.8083 1.2560 0.9966 1.2686 0.6573 0.9258 1.0633 0.6741 0.9902 1.3006
N-N-Dimethylglycine 1.0883 1.2358 0.9165 0.8635 0.9350 1.0706 1.0194 0.9060 1.0391 1.0206 0.9072
Nonanoic acid (pelargonate) 1.0803 0.9435 1.0310 0.9550 0.9828 1.0732 1.0515 0.9633 1.0723 0.9068 0.9449
N-(Pentadecanoyl)-ethanolamine 1.0715 1.3155 1.2214 0.9228 1.4267 0.9972 0.5492 1.2110 0.8856 0.4810 0.8135
N-Succinyl-L-citrulline 1.2875 0.9216 0.9986 0.9712 0.9211 1.0274 0.8888 0.9350 1.0313 1.1827 0.9258
N-(Tetradecanoyl)-ethanolamine 0.9224 1.9577 1.2603 0.7690 1.0309 1.8822 0.2020 1.0702 1.0322 0.4879 0.6524
O-Butanoylcarnitine 0.4868 0.9785 1.1414 0.8815 0.7248 0.6368 1.3312 1.3904 1.3985 1.2379 0.7541
Octanoic acid (caprylate) 0.6855 0.8097 0.9548 1.1750 1.3814 2.1044 0.6651 0.9925 0.8480 0.6441 0.7394
O-Propanoylcarnitine 0.9334 0.6892 0.9190 0.9621 0.7802 0.4654 1.1272 1.1591 1.6124 1.0013 1.2074
Ornithine 0.9848 1.3948 0.9759 0.9048 0.9986 0.9434 0.8975 1.0276 0.8772 1.0737 0.9706
Pantothenol 0.9816 1.1621 1.5848 1.1069 0.8169 1.0892 1.0436 0.7306 1.0209 0.8064 0.7833
phenylalanine 0.9198 0.9517 0.9818 0.8996 0.9295 0.9045 1.0521 1.2785 1.1072 1.0831 0.9253
Phosphocreatine 0.6430 1.0502 0.9774 0.6665 0.7940 3.0542 0.7397 0.4871 0.8045 0.4889 1.2070
Pregnenolone 1.3852 1.0730 1.1252 1.4397 0.8706 0.8668 0.1558 2.1046 0.6672 0.1982 0.6109
proline 0.9057 1.1752 0.8783 0.8062 0.8159 1.4102 0.9144 0.9103 1.1204 1.1118 0.9336
Protein glutamine 0.8287 0.7164 0.7112 0.6120 0.7854 1.6460 0.9911 1.2599 1.0628 1.2125 1.1384
Putrescine 0.6305 1.1610 0.5992 0.6608 0.5002 1.2700 0.5811 0.8651 3.1025 0.7437 0.5568
Pyridoxal 0.8822 1.3271 1.0746 0.9042 0.6935 1.6340 0.6160 1.0027 1.4023 0.8257 0.7394
Pyridoxamine phosphate 1.2403 0.9691 1.0587 1.0731 1.1419 1.0855 0.8097 0.8131 1.0800 0.8304 0.9287
Riboflavin 0.8872 1.1243 0.9633 0.9108 0.9862 0.9504 0.7841 0.7238 1.2514 1.2923 1.0306
S-Adenosyl-L-homocysteine 0.8668 1.1273 0.8884 0.8367 0.9730 1.2793 1.0224 1.0204 1.0517 0.9567 0.9358
S-Adenosyl-L-methionine 1.0793 1.4322 1.3101 1.1772 1.1024 1.1625 0.5368 0.7070 0.9096 0.6071 1.0710
(S)(+)-Allantoin 0.9874 0.9273 1.0990 1.0428 1.1950 1.0948 0.7254 0.8833 0.7100 1.3914 1.0095
Sarcosine 1.0952 1.0529 0.4470 0.6639 0.7763 1.5123 0.8160 0.8837 1.4004 1.0067 1.1935
serine 1.0558 1.5863 1.0126 0.6883 1.0354 0.6869 0.9299 1.3161 1.0077 1.0328 0.7754
S-Glutathionyl-L-cysteine 1.4107 0.7077 1.0324 0.8337 1.1803 0.8808 0.9701 1.0013 0.8681 1.0191 1.1507
Spermidine 0.6244 1.1138 0.9384 1.0165 0.7565 1.3248 0.6711 1.2261 1.6029 0.9179 0.7995
Spermine 0.3979 0.5626 0.4657 0.5365 0.5676 1.1781 1.7056 1.5167 1.3095 1.9364 0.6526
S-Ribosyl-L-homocysteine 1.0196 0.6524 0.7326 0.6303 0.8861 0.8537 1.2496 1.3306 1.2472 1.3125 1.0211
Taurine 0.9229 0.9640 0.7288 1.4775 0.6288 1.1766 1.0259 0.6078 1.4850 1.0835 0.7694
Taurocholate 0.8604 1.3111 0.7757 0.8926 0.7849 1.3173 NA 1.2053 1.1465 0.9675 0.7618
Tetradecenoic acid 0.7491 1.1555 0.9786 0.9834 0.7337 1.2183 NA 1.1630 1.0685 1.2275 0.9182
Tetrahydrofolate 1.1051 1.0050 0.8116 0.8870 1.0131 0.7880 1.0296 1.3171 0.9433 1.0418 1.0899
Threonate 1.2214 0.6972 0.5242 1.0733 1.0647 0.9098 0.9639 0.8992 0.8837 0.9967 1.5936
threonine 0.9473 1.7996 1.0411 0.7770 0.9678 0.3472 0.9987 1.0968 1.1651 0.9162 0.9449
trans-4-Hydroxy-L-proline 1.2327 0.6983 0.7210 1.0161 1.3128 0.8702 0.8006 1.1330 1.0616 1.3865 0.7912
Triacanthine 0.6311 0.8156 0.9377 0.9552 0.7195 0.6107 1.2705 1.2498 1.5337 1.3716 0.6247
tryptophan 1.0813 0.9991 0.9696 0.9274 1.0932 0.8920 0.9450 1.1403 0.9513 1.0202 1.0174
tyrosine 1.0537 0.9941 0.9602 0.9162 1.0726 1.0503 0.9213 1.1265 0.8688 1.1194 0.9771
Uracil 0.7208 0.9506 0.7337 0.7209 0.9359 1.2963 0.8534 1.0748 1.4182 0.8715 1.2401
Urate 1.1385 0.8132 1.0889 0.8272 1.0051 0.7635 0.9941 1.1871 1.2057 1.0597 0.9658
valine 1.0869 1.1572 0.5786 0.6209 1.1636 1.0519 1.1720 1.2699 0.8762 1.0816 1.0168
Xanthine 1.0065 0.9121 1.0061 0.9783 1.1956 0.9460 0.9200 0.9263 1.0331 0.7633 1.2256
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Factors:

F1time_point:I10
F2time_point:I2
F3time_point:I4
F4time_point:I6
F5time_point:I8
F6time_point:LD10
F7time_point:NP
F8time_point:P11-13
F9time_point:P18-20
F10time_point:P2-4
F11time_point:R4
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