Data for (Study ST001236)

(Analysis AN002054)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

MetaboliteF1F2F3F4F5F6F7F8F9F10F11F12F13F14F15F16F17F18
1,7-dimethyluric acid 1.0790 0.9274 1.0431 1.0224 1.0778 0.9348 1.0201 0.9770 0.9640 0.9090 1.0444 0.8589 1.0742 1.0582 0.9576 0.9616 1.0385 0.9760
1-methyladenosine 1.0034 0.9917 1.0013 1.0029 1.0049 1.0015 0.9988 0.9973 1.0065 1.0077 1.0089 0.9998 0.9989 0.9953 0.9994 0.9965 1.0024 0.9926
1-methylguanosine 1.0049 0.9926 0.9922 0.9911 1.0013 0.9909 1.0020 1.0014 1.0039 1.0072 1.0145 0.9914 1.0017 1.0004 0.9972 0.9920 1.0076 1.0090
1-methylnicotinamide 0.9824 0.9794 1.0085 0.9914 0.9908 0.9388 0.9987 1.0094 1.0368 1.0076 0.9976 1.0075 1.0000 1.0172 1.0256 1.0071 1.0012 0.9798
2-aminooctanoate 1.0147 0.9834 1.0787 0.9486 0.9895 0.9769 0.9867 0.9778 1.0382 0.9827 0.9601 0.9701 1.0241 1.0154 1.0986 0.9868 0.9979 0.9797
3-methylhistidine 0.9771 1.0052 1.0035 0.9842 1.0065 0.9693 0.9901 1.0005 1.0124 1.0001 1.0096 0.9863 0.9935 1.0110 0.9949 0.9832 1.0129 1.0103
3-methylxanthine 1.0145 0.9812 1.0294 1.0027 1.0428 0.9581 1.0363 0.9650 0.9961 0.9611 1.0175 0.9711 1.0182 0.9933 1.0476 0.9800 1.0129 0.9970
3-(N-acetyl-L-cystein-S-yl) acetaminophen 0.9116 0.8165 0.9613 1.0484 1.2322 0.9856 0.9893 1.0078 1.1324 1.0926 1.1548 0.5920 1.0079 0.8262 1.0381 1.0493 1.0797 0.9771
4-acetamidobutanoate 1.0017 0.9856 1.0045 1.0072 1.0122 0.9828 0.9855 0.9915 1.0050 1.0161 1.0141 0.9779 1.0042 1.0010 0.9985 1.0157 1.0095 1.0009
4-hydroxy-3-methylacetophenone 1.0114 0.9824 1.0343 0.9509 0.9771 1.0059 1.0005 0.9929 1.0243 0.9606 0.9931 0.9829 1.0376 1.0176 1.0468 1.0051 1.0065 1.0028
4-hydroxyhippurate 1.0349 0.9841 0.9863 0.9863 1.0424 0.9683 1.0147 0.9795 0.9906 0.9496 1.0052 0.9748 1.0591 1.0091 0.9911 1.0369 1.0098 1.0274
4-pyridoxate 1.0468 0.9763 1.0380 1.0078 1.0056 0.9783 1.0020 0.9839 1.0381 1.0098 1.0042 0.9768 1.0216 0.9896 0.9897 1.0359 0.9672 1.0087
5-hydroxytryptophan 1.0439 0.9364 0.9953 1.0200 1.0347 0.9882 1.0442 0.9296 1.0141 1.0519 1.0455 1.0310 1.0701 0.9658 1.0110 1.0184 1.0089 1.0840
5-hydroxytryptophol 1.0619 0.9886 0.9951 0.9738 0.9817 0.8557 1.0418 1.0186 1.0236 1.0359 0.9754 1.0241 1.0074 1.0004 0.9832 1.0305 1.0313 1.0222
7-methylguanine 1.0010 0.9919 1.0001 0.9926 1.0004 0.9908 0.9923 0.9953 1.0068 1.0091 1.0051 0.9914 1.0012 1.0063 1.0034 1.0135 1.0042 1.0089
8-hydroxy-deoxyguanosine 1.0179 0.9840 0.9926 0.9474 0.9712 0.9800 1.0132 1.0255 1.0493 0.9846 1.0456 1.0279 1.0472 0.9986 1.0278 0.9326 0.9702 0.9228
acetaminophen 0.9655 0.9045 1.0105 0.9661 1.1369 1.0997 1.0336 0.9142 1.0844 1.0310 1.0767 0.8007 1.0181 0.9812 1.0585 1.0322 1.0676 0.8894
acetaminophen glucuronide 1.0150 0.8437 0.9961 1.0159 1.1657 0.9777 0.9638 0.9915 1.0705 1.0081 1.0631 0.7272 1.0357 0.9358 1.0481 1.0024 0.9984 0.8776
acetyl-galactosamine 1.0153 0.9928 1.0013 0.9979 0.9918 1.0067 0.9987 0.9957 1.0122 1.0011 1.0033 0.9934 1.0079 0.9976 1.0064 1.0027 0.9949 1.0162
adenosine 1.0197 0.9890 1.0208 0.9795 0.9938 1.0083 0.9833 0.9901 1.0426 0.9810 1.0041 0.9868 1.0453 1.0083 1.0155 0.9646 1.0004 0.9538
alanine 1.0123 0.9974 1.0034 0.9898 0.9986 0.9921 1.0018 0.9984 1.0095 0.9875 0.9939 0.9941 1.0241 1.0068 1.0032 0.9823 0.9977 1.0115
allantoin 1.0091 0.9696 0.9860 0.9763 0.9850 0.9576 0.9968 0.9973 1.0103 0.9954 1.0264 0.9728 1.0340 1.0267 1.0071 0.9956 1.0522 1.0123
allopurinol riboside 1.1150 0.8678 0.9086 0.6087 1.1213 1.1924 0.9870 0.8140 1.0092 0.6931 1.3909 1.4832 1.3324 1.0442 0.8489 0.7753 1.0959 2.5412
alpha-glycerophosphocholine 0.9996 0.9901 0.9949 1.0045 1.0081 0.9898 0.9944 0.9858 0.9997 1.0025 1.0119 0.9765 0.9991 1.0048 1.0077 0.9948 1.0268 1.0305
anthranilic acid 0.9786 0.9767 0.9401 0.9129 1.0578 0.9587 0.9577 0.9636 1.0017 0.9798 1.0645 1.2305 1.0435 1.0229 0.9769 1.0412 1.0639 0.9773
arginine 1.0117 0.9972 1.0041 1.0020 0.9959 1.0030 1.0013 0.9995 1.0083 0.9992 0.9900 1.0057 1.0135 1.0039 1.0052 0.9807 0.9848 1.0039
asparagine 1.0099 0.9967 0.9950 0.9985 0.9971 1.0014 0.9960 0.9965 1.0057 0.9990 0.9962 1.0007 1.0141 1.0081 1.0013 0.9861 0.9974 1.0109
atenolol 1.5663 0.7638 0.6376 NA 1.0781 0.5202 1.9494 0.6215 NA 0.5242 1.1789 0.4812 1.4334 0.5551 0.5434 0.5182 1.4775 NA
betaine 1.0038 0.9987 0.9992 1.0064 0.9965 1.0014 0.9956 0.9991 1.0016 1.0115 0.9939 0.9990 1.0030 1.0020 1.0018 1.0021 0.9930 1.0007
bilirubin 1.0130 0.9919 0.9998 1.0124 0.9845 0.9968 1.0061 1.0077 1.0104 1.0141 1.0033 1.0069 1.0076 1.0061 1.0017 0.9738 0.9693 0.9878
biliverdin 1.0090 0.9952 0.9977 1.0030 0.9832 0.9917 1.0052 1.0130 1.0113 1.0067 0.9967 0.9954 1.0059 1.0079 0.9998 0.9789 0.9946 0.9713
butyrobetaine 1.0072 0.9958 0.9888 0.9936 1.0007 0.9948 1.0039 1.0064 0.9938 1.0004 1.0015 0.9925 1.0082 1.0072 0.9899 0.9876 1.0102 1.0046
C10 carnitine 0.9893 0.9815 0.9818 0.9818 1.0002 0.9811 1.0287 1.0313 1.0062 1.0306 1.0368 0.9927 0.9874 0.9880 0.9691 0.9535 1.0229 0.9934
C12:1 carnitine 0.9880 0.9798 0.9877 0.9833 0.9975 0.9807 1.0239 1.0298 1.0106 1.0355 1.0347 0.9899 0.9822 0.9879 0.9775 0.9556 1.0221 0.9941
C12 carnitine 0.9910 0.9812 0.9821 0.9889 0.9969 0.9816 1.0252 1.0295 1.0051 1.0310 1.0346 0.9825 0.9944 0.9899 0.9750 0.9588 1.0225 0.9853
C14:0 LPC 0.9964 0.9955 1.0100 0.9932 0.9987 0.9654 0.9957 0.9927 1.0182 0.9748 1.0021 0.9780 1.0165 1.0189 1.0251 0.9761 1.0050 1.0104
C14:0 SM 1.0046 0.9942 1.0033 0.9987 0.9979 0.9800 1.0022 0.9980 1.0108 0.9933 1.0031 0.9831 1.0094 1.0087 1.0106 0.9837 1.0064 0.9929
C14:1 carnitine 0.9807 0.9797 0.9803 0.9868 0.9977 0.9876 1.0177 1.0335 1.0035 1.0424 1.0394 0.9964 0.9790 0.9868 0.9686 0.9588 1.0228 1.0026
C14:2 carnitine 0.9893 0.9802 0.9844 0.9776 0.9915 0.9867 1.0213 1.0365 1.0112 1.0403 1.0329 0.9861 0.9824 0.9889 0.9735 0.9496 1.0246 0.9970
C14 carnitine 0.9924 0.9820 0.9916 0.9946 0.9958 0.9786 1.0187 1.0183 1.0070 1.0241 1.0323 0.9730 0.9938 0.9906 0.9854 0.9782 1.0242 0.9954
C16:0 ceramide (d18:1) 0.9980 0.9868 0.9901 1.0102 0.9997 1.0164 1.0039 0.9925 1.0054 1.0106 1.0105 1.0105 1.0067 0.9947 0.9973 0.9940 1.0136 1.0015
C16:0 LPC 0.9948 0.9981 1.0027 0.9960 0.9943 0.9921 0.9947 0.9988 1.0115 0.9920 0.9969 0.9940 1.0057 1.0116 1.0122 0.9834 1.0001 1.0097
C16:0 LPE 0.9871 0.9911 1.0103 0.9919 0.9950 0.9924 0.9876 0.9888 1.0262 0.9845 1.0005 0.9877 1.0091 1.0151 1.0287 0.9854 1.0063 1.0193
C16:0 SM 1.0045 0.9935 0.9984 0.9971 0.9966 0.9985 1.0027 0.9989 1.0078 0.9985 1.0040 0.9984 1.0052 1.0024 1.0063 0.9909 1.0032 0.9980
C16:1 LPC 0.9851 0.9929 1.0064 0.9937 0.9973 0.9839 0.9870 0.9958 1.0181 0.9838 1.0061 1.0038 1.0050 1.0108 1.0208 0.9866 1.0032 1.0191
C16:1 LPC plasmalogen 0.9925 0.9948 1.0022 0.9909 0.9918 0.9735 0.9958 0.9999 1.0174 0.9934 0.9980 0.9783 1.0132 1.0196 1.0191 0.9792 1.0064 1.0049
C16:1 SM 1.0037 0.9945 1.0046 0.9957 0.9952 0.9918 1.0013 0.9996 1.0137 0.9942 1.0018 0.9888 1.0052 1.0059 1.0115 0.9836 1.0047 0.9893
C16 carnitine 0.9873 0.9901 0.9955 0.9996 0.9924 0.9911 1.0099 1.0105 1.0079 1.0188 1.0106 0.9910 0.9940 0.9955 0.9930 0.9890 1.0140 1.0106
C18:0 LPC 0.9955 0.9976 1.0063 0.9928 0.9947 0.9820 0.9959 0.9974 1.0134 0.9919 0.9966 0.9884 1.0062 1.0144 1.0183 0.9781 1.0013 1.0121
C18:0 LPE 0.9898 0.9923 1.0117 0.9910 0.9963 0.9862 0.9901 0.9914 1.0231 0.9861 0.9991 0.9853 1.0053 1.0158 1.0271 0.9776 1.0075 1.0190
C18:0 SM 1.0017 0.9939 0.9993 0.9952 1.0014 1.0141 1.0038 0.9975 1.0057 0.9967 1.0078 1.0099 0.9979 0.9947 0.9993 0.9882 1.0080 1.0025
C18:1 carnitine 0.9899 0.9904 0.9891 1.0069 0.9937 0.9997 1.0079 1.0109 0.9993 1.0263 1.0178 0.9991 0.9819 0.9920 0.9846 0.9940 1.0094 1.0160
C18:1 LPC 0.9905 0.9951 1.0030 0.9964 0.9912 0.9953 0.9916 0.9974 1.0126 0.9926 1.0015 0.9989 1.0046 1.0105 1.0159 0.9935 0.9955 1.0222
C18:1 LPC plasmalogen_A 0.9917 0.9928 0.9959 0.9976 0.9932 0.9761 0.9975 1.0011 1.0103 1.0076 1.0048 0.9836 1.0047 1.0092 1.0176 0.9825 1.0090 1.0155
C18:1 LPC plasmalogen_B 0.9936 0.9968 0.9994 0.9829 0.9845 0.9717 0.9970 1.0038 1.0210 0.9836 0.9937 0.9719 1.0236 1.0300 1.0234 0.9568 1.0094 1.0024
C18:1 LPE 0.9951 0.9979 1.0147 0.9956 0.9879 0.9978 0.9838 0.9800 1.0189 0.9829 0.9920 0.9790 1.0239 1.0218 1.0291 0.9978 0.9909 1.0392
C18:1 SM 1.0004 0.9946 1.0062 0.9950 0.9980 1.0051 1.0028 0.9985 1.0142 0.9939 1.0033 1.0001 0.9975 0.9981 1.0070 0.9855 1.0064 0.9948
C18:2 carnitine 0.9962 0.9922 0.9935 1.0029 0.9907 0.9937 1.0088 1.0132 0.9977 1.0254 1.0162 0.9777 0.9886 0.9920 0.9832 0.9793 1.0225 1.0205
C18:2 LPE 1.0027 0.9928 1.0153 0.9917 0.9846 1.0052 0.9880 0.9771 1.0247 0.9819 0.9850 0.9805 1.0377 1.0261 1.0317 0.9936 0.9930 1.0284
C18:2 SM 1.0071 0.9953 1.0124 0.9952 0.9935 1.0014 1.0057 0.9980 1.0226 0.9851 1.0021 0.9891 0.9985 0.9992 1.0119 0.9805 1.0088 0.9806
C18:3 LPC 0.9964 0.9982 1.0026 0.9961 0.9957 0.9946 0.9946 0.9991 1.0105 0.9927 0.9983 0.9951 1.0049 1.0100 1.0099 0.9828 1.0004 1.0048
C18 carnitine 0.9949 0.9849 0.9798 0.9963 0.9911 0.9933 1.0263 1.0084 1.0096 1.0058 0.9969 0.9987 1.0192 1.0042 1.0099 0.9788 1.0084 1.0155
C20:0 LPE 0.9936 0.9967 1.0017 0.9932 0.9973 0.9788 0.9953 0.9993 1.0106 0.9924 0.9968 0.9882 1.0074 1.0162 1.0106 0.9840 1.0040 1.0168
C20:0 SM 1.0033 0.9957 0.9981 0.9959 0.9965 0.9986 1.0045 0.9994 1.0039 0.9930 1.0018 1.0024 1.0061 1.0062 1.0040 0.9845 1.0029 1.0022
C20:4 carnitine 1.0731 0.9860 0.9882 1.0522 0.9704 0.9847 1.0164 1.0041 1.0036 1.0530 1.0329 0.9768 0.9512 0.9657 0.9276 1.0214 1.0223 1.0339
C20:4 LPC 0.9896 0.9994 1.0034 0.9949 0.9903 0.9949 0.9897 1.0015 1.0119 0.9930 0.9990 0.9965 1.0034 1.0086 1.0137 0.9907 0.9984 1.0138
C20:4 LPE 0.9911 0.9946 1.0067 0.9950 0.9900 1.0030 0.9874 0.9923 1.0173 0.9958 0.9962 0.9864 1.0125 1.0156 1.0178 0.9872 0.9984 1.0223
C20:5 LPC 0.9986 1.0001 1.0054 0.9919 0.9907 0.9977 0.9900 0.9949 1.0139 0.9847 0.9919 0.9896 1.0204 1.0155 1.0162 0.9933 0.9913 1.0142
C22:5 LPC 0.9801 0.9975 1.0064 0.9879 0.9873 0.9910 0.9881 1.0014 1.0217 0.9787 0.9998 0.9863 1.0092 1.0199 1.0257 0.9753 0.9991 1.0159
C22:6 LPC 0.9846 0.9997 0.9982 0.9919 0.9926 0.9988 0.9851 1.0016 1.0106 0.9920 1.0021 0.9994 0.9979 1.0146 1.0159 0.9782 0.9959 1.0224
C22:6 LPE 0.9813 0.9964 0.9959 0.9899 1.0020 1.0047 0.9821 0.9988 1.0126 0.9997 1.0095 0.9921 0.9895 1.0144 1.0085 0.9730 1.0039 1.0224
C24:1 ceramide (d18:1) 0.9992 0.9905 0.9966 1.0032 0.9970 1.0060 1.0021 0.9959 1.0100 1.0028 1.0037 1.0058 1.0089 1.0008 1.0030 0.9943 1.0061 0.9943
C26 carnitine 1.0092 0.9882 0.9901 0.9871 0.9872 0.9894 1.0036 1.0042 1.0195 0.9957 1.0047 0.9897 1.0123 1.0169 1.0122 0.9785 1.0104 0.9736
C2 carnitine 0.9971 0.9925 0.9997 0.9902 0.9991 0.9955 0.9987 1.0100 1.0061 0.9997 1.0112 0.9933 0.9963 1.0015 1.0007 0.9723 1.0084 1.0040
C30:0 PC 0.9976 0.9938 1.0076 0.9968 1.0010 0.9799 1.0012 0.9914 1.0177 0.9815 1.0137 0.9798 1.0060 1.0045 1.0198 0.9882 1.0092 0.9975
C32:2 PC 1.0023 0.9941 1.0075 0.9917 1.0036 0.9781 0.9987 0.9952 1.0135 0.9771 1.0042 0.9873 1.0123 1.0130 1.0155 0.9740 1.0118 0.9885
C34:0 PE 0.9987 0.9944 1.0021 0.9998 1.0052 0.9783 1.0070 0.9963 1.0140 0.9931 1.0138 0.9783 0.9984 0.9975 1.0073 0.9991 1.0097 0.9961
C34:1 DAG 1.0016 0.9962 1.0037 1.0101 1.0025 0.9943 0.9982 0.9893 1.0185 0.9984 0.9948 0.9876 1.0040 1.0050 1.0094 0.9781 1.0020 1.0153
C34:1 DAG* 0.9984 1.0042 1.0071 0.9749 1.0054 0.9751 0.9824 1.0153 1.0135 0.9720 0.9913 0.9550 0.9939 1.0369 0.9994 0.9354 1.0094 1.0067
C34:2 DAG 0.9724 1.0126 1.0227 0.9442 1.0067 0.9473 0.9635 1.0404 1.0126 0.9497 0.9987 0.9345 0.9747 1.0559 1.0032 0.9064 1.0153 0.9887
C34:2 PE 1.0093 0.9883 1.0114 0.9957 1.0022 1.0101 0.9983 0.9826 1.0223 0.9869 0.9971 0.9973 1.0122 1.0011 1.0161 0.9959 1.0118 1.0047
C34:2 PE plasmalogen 0.9963 0.9906 0.9994 0.9994 0.9908 0.9861 0.9994 0.9974 1.0125 0.9952 1.0000 0.9897 1.0184 1.0134 1.0145 0.9961 0.9969 1.0149
C34:3 PC 0.9961 0.9981 1.0069 0.9906 0.9988 0.9925 0.9935 0.9996 1.0100 0.9823 1.0047 0.9975 1.0015 1.0113 1.0088 0.9831 1.0019 0.9947
C34:3 PC plasmalogen 1.0006 0.9935 0.9989 0.9967 0.9963 0.9904 1.0044 0.9992 1.0100 1.0027 0.9981 0.9850 1.0118 1.0066 1.0080 1.0028 1.0037 0.9876
C34:3 PE plasmalogen 1.0029 0.9917 1.0025 0.9966 0.9894 0.9810 1.0071 0.9923 1.0153 0.9945 0.9900 0.9851 1.0309 1.0192 1.0186 0.9911 0.9957 1.0075
C34:4 PC 1.0018 1.0002 1.0121 0.9832 1.0052 0.9503 0.9989 1.0004 1.0117 0.9589 1.0081 0.9808 1.0104 1.0196 1.0197 0.9612 1.0113 0.9932
C36:2 PC 1.0026 0.9961 1.0039 0.9974 0.9979 0.9959 1.0010 0.9954 1.0075 0.9963 0.9994 0.9967 1.0053 1.0046 1.0094 0.9939 1.0005 1.0018
C36:2 PE 1.0105 0.9927 1.0122 0.9934 1.0007 0.9992 0.9986 0.9838 1.0140 0.9813 0.9929 0.9940 1.0144 1.0115 1.0188 0.9931 1.0043 1.0077
C36:2 PS plasmalogen 1.0004 0.9986 0.9951 0.9879 0.9996 1.0002 1.0023 1.0057 1.0054 0.9972 1.0068 0.9940 0.9967 1.0030 1.0031 0.9782 1.0053 0.9919
C36:3 PE plasmalogen 1.0055 0.9916 1.0039 0.9986 0.9908 0.9877 1.0075 0.9918 1.0156 0.9932 0.9927 0.9888 1.0255 1.0140 1.0167 0.9957 0.9935 1.0046
C36:4 PE 1.0021 0.9911 1.0090 0.9974 1.0028 1.0061 0.9949 0.9943 1.0140 0.9943 1.0009 0.9978 0.9998 0.9973 1.0089 0.9979 1.0079 1.0062
C36:5 PC plasmalogen 0.9987 0.9946 0.9953 1.0002 0.9976 0.9888 1.0018 1.0022 1.0048 1.0047 1.0009 0.9876 1.0069 1.0042 1.0057 0.9974 1.0066 0.9936
C36:5 PE plasmalogen 0.9982 0.9961 1.0014 1.0011 0.9918 0.9841 0.9996 0.9987 1.0072 1.0032 0.9930 0.9854 1.0174 1.0122 1.0109 0.9943 0.9956 1.0103
C38:4 PE 1.0024 0.9937 1.0093 0.9955 1.0039 0.9978 0.9994 0.9964 1.0129 0.9919 0.9998 1.0012 0.9990 0.9984 1.0089 0.9895 1.0061 1.0025
C38:5 PE plasmalogen 1.0008 0.9946 1.0030 1.0013 0.9934 0.9869 1.0010 0.9977 1.0113 1.0010 0.9930 0.9831 1.0175 1.0091 1.0114 0.9974 0.9970 1.0053
C38:6 PC plasmalogen 0.9967 0.9953 0.9972 0.9966 0.9995 0.9891 0.9957 1.0021 1.0072 0.9998 1.0044 0.9882 1.0026 1.0066 1.0077 0.9893 1.0064 0.9971
C38:6 PE 0.9977 0.9928 1.0028 0.9937 1.0139 1.0037 0.9935 0.9976 1.0126 0.9961 1.0090 1.0073 0.9836 0.9941 1.0026 0.9883 1.0089 1.0055
C38:6 PE plasmalogen 0.9955 0.9966 1.0016 0.9990 0.9940 0.9855 0.9964 1.0006 1.0088 0.9980 0.9948 0.9861 1.0115 1.0122 1.0128 0.9899 0.9965 1.0107
C38:7 PC plasmalogen 0.9950 0.9938 0.9922 0.9958 1.0031 0.9878 0.9936 1.0025 1.0051 1.0046 1.0062 0.9874 1.0005 1.0097 1.0058 0.9894 1.0042 1.0029
C38:7 PE plasmalogen 0.9953 0.9976 0.9974 0.9959 0.9972 0.9909 0.9944 1.0029 1.0067 0.9997 1.0006 0.9950 0.9993 1.0094 1.0092 0.9836 0.9980 1.0105
C3 carnitine 1.0030 0.9923 1.0025 1.0048 1.0048 0.9870 0.9971 0.9950 0.9979 0.9876 1.0064 0.9939 1.0147 1.0065 0.9954 0.9830 1.0145 1.0217
C3-DC-CH3 carnitine 1.0129 0.9931 0.9898 1.0010 1.0142 0.9707 1.0038 0.9949 0.9910 1.0103 1.0080 0.9891 1.0069 0.9992 0.9842 1.0147 1.0207 1.0112
C40:6 PE 0.9979 0.9946 1.0054 0.9884 1.0150 0.9993 0.9932 1.0003 1.0113 0.9867 1.0085 1.0074 0.9826 0.9967 1.0052 0.9777 1.0111 1.0049
C40:7 PE plasmalogen 0.9974 0.9951 1.0007 0.9953 0.9969 0.9891 0.9945 0.9991 1.0124 0.9973 0.9988 0.9921 1.0038 1.0094 1.0105 0.9978 0.9989 1.0081
C4 carnitine 0.9998 0.9960 1.0049 0.9923 0.9961 0.9687 0.9953 1.0052 1.0041 0.9902 1.0151 0.9785 1.0068 1.0091 1.0017 0.9710 1.0190 1.0037
C4-OH carnitine 0.9733 0.9883 1.0187 0.9762 0.9977 1.0215 0.9915 1.0232 1.0319 1.0031 1.0147 1.0060 0.9665 0.9889 0.9917 0.9863 0.9994 0.9946
C5:1 carnitine 1.0077 0.9912 0.9995 1.0007 0.9956 0.9699 1.0129 1.0040 1.0008 1.0254 1.0092 0.9791 1.0089 0.9985 0.9831 1.0090 1.0121 0.9947
C5 carnitine 1.0099 0.9993 1.0052 1.0006 0.9985 0.9871 1.0063 1.0038 0.9993 0.9943 0.9955 0.9864 1.0158 1.0050 0.9868 0.9923 1.0013 1.0011
C5-DC carnitine 1.0076 0.9970 0.9795 1.0148 1.0004 0.9786 1.0026 1.0054 0.9782 1.0314 1.0064 0.9846 1.0094 1.0047 0.9772 1.0054 1.0109 0.9937
C6 carnitine 0.9943 0.9827 0.9912 0.9896 1.0062 0.9948 1.0031 1.0182 1.0022 1.0090 1.0240 1.0005 0.9821 0.9958 0.9914 0.9573 1.0196 1.0154
C8 carnitine 0.9928 0.9809 0.9810 0.9752 1.0029 0.9786 1.0273 1.0321 1.0075 1.0239 1.0374 0.9897 0.9898 0.9934 0.9657 0.9426 1.0281 0.9936
C9 carnitine 1.0373 0.9735 0.9695 0.9821 0.9816 0.9440 1.0589 1.0362 0.9841 1.0102 1.0294 0.9247 1.0344 1.0029 1.0079 0.9537 1.0216 0.9504
caffeine 1.1240 0.9704 0.9996 1.0111 1.0672 0.9724 1.0242 0.9214 0.9666 0.9453 1.0019 0.8828 1.1072 1.0245 1.0052 0.9964 1.0430 1.0403
carnitine 1.0023 0.9954 1.0000 0.9973 1.0006 0.9965 0.9985 0.9995 1.0038 0.9950 1.0011 1.0047 1.0064 1.0017 1.0012 0.9839 1.0071 1.0128
carvedilol NA 1.2377 1.1752 0.6174 1.3694 NA NA 1.2031 0.7323 0.4316 1.3541 NA NA 1.2620 NA NA NA NA
choline 1.0078 0.9968 1.0029 0.9995 1.0011 0.9935 0.9976 0.9986 1.0012 0.9976 0.9944 0.9911 1.0122 1.0077 1.0044 0.9813 1.0015 1.0051
cinnamoylglycine 0.9951 0.9990 0.9959 0.9976 1.0063 0.9398 0.9843 1.0039 1.0002 1.0255 1.0129 0.9163 1.0049 1.0223 1.0069 0.9978 1.0041 1.0062
citrulline 1.0164 0.9923 1.0007 0.9960 0.9995 0.9696 1.0052 0.9945 1.0113 1.0032 1.0011 0.9910 1.0212 1.0114 1.0048 0.9983 0.9888 0.9985
cortisol 0.9861 1.0141 0.9895 1.0097 0.9971 0.9257 1.0067 1.0171 1.0091 1.0493 1.0274 0.9450 0.9485 0.9934 0.9884 1.0081 0.9956 0.9908
cortisone 0.9989 1.0325 0.9838 1.0283 0.9706 0.9499 1.0018 1.0413 1.0037 1.0525 0.9997 1.0053 0.9000 1.0020 0.9712 0.9895 0.9607 0.9432
cotinine 0.9848 0.9695 1.0483 0.9628 0.9721 1.2052 0.9068 1.0098 0.9832 1.0110 1.0304 1.2050 0.8830 0.9623 1.0830 0.8705 0.9927 1.0596
cotinine N-oxide 1.0142 0.9863 1.0430 1.0034 0.9825 0.9538 1.0219 0.9740 1.0378 1.0051 0.9629 0.9295 1.0395 1.0160 1.0675 0.9863 1.0183 0.9735
creatine 0.9777 0.9954 1.0052 0.9953 1.0065 0.9822 0.9682 1.0081 1.0116 0.9580 1.0081 0.9894 0.9857 1.0184 1.0128 0.9749 1.0248 1.0150
creatinine 1.0035 0.9973 1.0000 0.9985 0.9976 0.9927 1.0006 1.0014 1.0048 1.0056 0.9999 0.9906 1.0028 1.0040 1.0006 0.9948 0.9996 0.9974
cytosine 1.0578 0.9892 1.0165 0.9965 1.0055 0.9618 1.0098 0.9809 1.0068 0.9799 1.0019 0.9693 1.0382 1.0026 1.0241 0.9866 0.9872 1.0265
diacetylspermine 0.9553 0.9607 1.0013 1.0295 1.0443 1.0545 0.9548 0.9742 1.0046 1.0904 1.0715 0.9899 0.9509 0.9555 0.9906 1.0700 1.0118 0.9970
dimethylglycine 0.9933 0.9941 0.9958 1.0096 0.9993 0.9969 0.9862 1.0057 1.0024 1.0150 1.0002 0.9931 0.9961 1.0057 0.9953 0.9995 1.0002 1.0018
DMGV 1.0300 0.9729 1.0198 1.0241 1.0267 0.9767 1.0118 0.9580 1.0296 1.0196 1.0313 0.9504 1.0234 0.9573 1.0248 1.0152 1.0288 1.0243
ectoine 0.9717 1.0075 1.0404 0.9921 0.9830 0.9313 0.9707 1.0064 1.0267 0.9963 0.9964 0.9403 0.9908 1.0188 1.0001 1.0069 1.0299 1.0208
GABA 0.9998 1.0090 0.9901 0.9890 0.9845 1.0027 0.9967 1.0247 1.0018 0.9894 0.9885 1.0014 1.0037 1.0163 0.9831 0.9728 0.9872 0.9952
gabapentin 1.0557 0.9901 1.0346 1.0048 0.9574 0.9560 1.0535 0.9833 0.9612 0.9471 1.0027 0.9541 1.0755 1.0354 0.9535 0.9523 1.0200 1.1497
glutamate 1.0035 0.9997 0.9947 1.0173 1.0159 1.0033 0.9925 1.0028 0.9930 0.9864 0.9997 0.9898 0.9616 1.0075 0.9846 0.9653 1.0195 1.0247
glutamine 1.0036 0.9947 1.0032 0.9958 0.9958 1.0018 0.9962 0.9961 1.0105 0.9974 1.0006 0.9999 1.0089 1.0064 1.0083 0.9882 0.9962 1.0043
glycocholate 1.0044 0.9934 1.0040 0.9952 0.9953 1.0016 0.9950 0.9950 1.0124 0.9967 1.0013 0.9997 1.0116 1.0078 1.0098 0.9852 0.9955 1.0060
glycodeoxycholate/glycochenodeoxycholate 1.0608 1.0255 0.9741 1.0043 1.0310 1.0453 0.9773 0.9635 0.9293 0.9605 0.9840 0.9811 1.0675 1.0187 0.9657 0.9800 1.0166 1.0400
guanine 1.0474 1.0073 1.0502 0.8422 0.9123 0.8669 1.0566 1.0252 0.9385 0.9558 0.9948 1.0359 1.1660 1.0781 1.0078 0.9744 0.9675 0.9297
hippurate 0.9928 0.9938 0.9946 0.9851 0.9944 0.9995 0.9948 1.0017 1.0077 1.0172 1.0137 1.0069 0.9847 1.0041 0.9992 1.0066 0.9948 1.0216
histidine 1.0017 0.9970 1.0011 0.9911 0.9935 0.9912 0.9940 1.0004 1.0096 0.9896 0.9969 1.0027 1.0127 1.0147 1.0115 0.9798 0.9937 1.0079
hydroxycotinine 0.9966 0.9835 0.9828 1.0038 0.9908 1.2481 0.8170 1.0110 0.9528 0.9284 1.0348 1.2176 0.8674 1.0185 0.9797 0.9358 0.9768 1.1462
hydroxyproline 1.0005 1.0058 0.9870 0.9872 0.9991 0.9814 0.9939 1.0044 0.9917 0.9899 1.0019 0.9879 1.0259 1.0100 1.0002 0.9930 1.0018 1.0190
hypotaurine 1.0158 0.9806 0.9630 1.0231 1.0257 0.9974 1.0091 0.9783 0.9812 1.0447 1.0327 0.9574 1.0175 0.9839 0.9756 0.9741 1.0495 1.0666
hypoxanthine 1.0068 0.9976 0.9990 0.9947 1.0059 0.9898 1.0053 0.9992 1.0040 0.9995 1.0057 0.9878 1.0009 1.0025 0.9995 0.9811 1.0029 1.0026
imidazole propionate 0.9955 0.9721 0.9738 1.0276 1.0216 1.0295 0.9895 0.9684 0.9838 1.0492 1.0348 0.9931 1.0304 0.9892 0.9972 1.0334 1.0200 0.9890
inosine 1.0136 0.9944 1.0015 0.9618 0.9919 0.9902 1.0023 1.0163 1.0291 0.9944 1.0204 1.0215 1.0237 1.0092 1.0092 0.9388 0.9732 0.9294
Kyn/Trp 0.9383 0.9068 0.9216 0.9167 0.8741 0.9075 1.0816 1.0772 1.0579 1.1340 1.0127 0.8482 1.1840 0.8898 1.1216 1.6981 1.0035 0.8329
kynurenic acid 1.0279 0.9991 0.9991 0.9875 0.9806 0.9549 1.0175 1.0092 1.0203 1.0196 0.9949 0.9612 1.0144 1.0088 1.0042 0.9760 1.0024 0.9799
kynurenine 1.0051 0.9918 0.9968 0.9937 0.9883 0.9813 1.0096 1.0044 1.0111 1.0124 0.9956 0.9939 1.0175 1.0050 1.0090 1.0092 0.9906 0.9998
Kynurenine_μM 1.0329 0.9232 0.9355 0.8995 0.8418 0.7860 1.1048 1.0823 1.1490 1.1594 0.9301 0.8845 1.2439 1.0416 1.1036 1.1838 0.8872 0.9620
leucine 0.9995 0.9987 0.9941 0.9972 0.9968 0.9908 1.0015 1.0028 1.0046 1.0005 1.0019 0.9949 1.0015 1.0118 0.9960 0.9813 0.9973 1.0085
linoleoyl ethanolamide 0.9339 1.0086 0.9888 1.0108 1.0210 0.9628 1.0265 1.0064 1.0879 1.0184 1.0327 0.8992 0.8970 1.0060 1.0285 0.8986 1.0719 0.9258
lysine 1.0082 0.9969 1.0001 0.9975 0.9999 1.0013 0.9966 1.0001 1.0044 0.9915 0.9928 1.0037 1.0130 1.0122 0.9962 0.9793 0.9928 1.0103
metformin 0.9370 1.0463 1.0230 0.9420 0.9428 1.0788 0.9421 1.0367 1.0131 0.9450 0.9457 1.1047 0.9446 1.0395 0.9756 0.9476 0.9524 1.1655
methionine 1.0041 0.9937 1.0018 0.9954 0.9935 1.0035 0.9999 1.0004 1.0131 0.9950 0.9974 0.9984 1.0098 1.0089 1.0017 0.9818 0.9974 1.0075
metoprolol 0.4892 0.8442 1.3285 1.2745 1.7299 0.7111 0.4714 0.8446 1.1795 0.9766 1.5481 0.3967 0.1987 0.8033 1.3063 0.9539 1.5189 0.6665
metronidazole 1.0155 0.8601 0.9971 1.2455 0.9577 1.0046 0.9456 1.0000 1.0065 1.2398 1.0046 0.9138 0.9955 1.0661 0.9380 1.2720 0.8146 1.0018
myristoleate 1.0086 0.9957 1.0089 0.9839 0.9881 1.0023 1.0017 0.9991 1.0110 0.9875 1.0017 1.0036 1.0128 1.0041 1.0142 0.9806 0.9997 1.0039
N1-acetylspermidine 0.9962 0.9855 0.9963 1.0092 1.0014 1.0120 1.0023 0.9985 1.0114 1.0241 1.0075 1.0112 0.9944 0.9932 0.9938 1.0071 0.9938 1.0019
N1-methyl-2-pyridone-5-carboxamide 1.0056 0.9845 1.0203 0.9908 0.9967 0.9541 1.0031 1.0019 1.0242 1.0108 1.0029 0.9927 1.0081 1.0024 1.0168 0.9944 0.9986 0.9926
N4-acetylcytidine 0.9999 0.9916 0.9979 0.9975 1.0040 0.9988 0.9941 0.9982 1.0067 1.0212 1.0150 0.9903 0.9908 0.9939 0.9923 1.0019 1.0149 0.9997
N6-acetyllysine 0.9973 0.9976 0.9996 0.9987 0.9938 0.9940 0.9863 1.0003 1.0165 1.0070 0.9978 0.9963 0.9952 1.0088 1.0005 0.9981 0.9954 1.0181
N6,N6-dimethyllysine 1.0008 0.9872 1.0073 0.9963 1.0118 0.9974 0.9956 0.9926 1.0165 0.9949 1.0142 0.9977 1.0019 0.9941 0.9991 0.9858 1.0119 1.0200
N6,N6,N6-trimethyllysine 1.0003 0.9951 1.0022 1.0066 0.9984 0.9862 0.9988 1.0026 1.0081 1.0048 0.9993 0.9877 1.0049 1.0057 0.9914 0.9986 0.9997 1.0021
N-acetylalanine 1.0088 0.9917 0.9969 0.9975 0.9937 0.9926 1.0018 0.9997 1.0132 1.0043 1.0032 0.9886 1.0093 1.0015 1.0018 0.9921 1.0075 1.0100
N-acetylleucine 1.0014 0.9784 1.0277 1.0034 0.9880 1.0041 1.0033 0.9816 1.0242 0.9804 0.9942 0.9911 1.0331 1.0048 1.0359 1.0121 1.0094 0.9855
N-acetylmethionine 1.0104 0.9865 1.0067 1.0029 1.0062 0.9757 1.0016 0.9951 1.0086 1.0117 1.0077 0.9478 1.0161 1.0021 1.0080 1.0227 0.9892 1.0199
N-acetylornithine 1.0072 0.9959 0.9999 0.9688 1.0074 0.9606 0.9972 0.9899 1.0206 1.0032 1.0119 0.9931 1.0193 1.0068 1.0149 0.9716 1.0114 1.0161
N-acetylputrescine 0.9985 0.9777 0.9951 1.0205 1.0185 1.0106 0.9873 0.9858 1.0032 1.0261 1.0198 1.0160 0.9984 0.9910 0.9864 1.0253 0.9985 1.0144
N-acetyltryptophan 1.0188 1.0080 0.9935 1.0188 0.9932 0.9649 1.0028 1.0027 0.9950 1.0165 0.9903 0.9492 1.0088 1.0208 0.9952 1.0057 0.9697 0.9958
N-alpha-acetylarginine 1.0142 0.9946 1.0151 1.0041 0.9828 0.9421 1.0012 0.9991 1.0164 1.0211 0.9789 0.9523 1.0302 1.0308 1.0097 1.0183 0.9746 0.9895
N-carbamoyl-beta-alanine 0.9840 0.9905 0.9747 1.0048 1.0126 1.0107 0.9748 0.9966 0.9935 1.0382 1.0307 1.0011 0.9904 0.9990 0.9808 1.0279 1.0124 0.9769
niacinamide 0.9957 1.0026 1.0185 0.9947 1.0015 0.9797 1.0121 1.0097 0.9823 0.9797 0.9786 0.9648 0.9745 1.0189 0.9847 1.0115 1.0192 1.0368
N-methylproline 1.0115 0.9979 0.9784 1.0091 1.0376 0.9553 0.9816 0.9815 0.9730 1.0420 1.0304 0.9550 1.0249 0.9983 0.9578 1.0325 1.0476 0.9601
NMMA 1.0043 1.0045 1.0035 0.9990 0.9889 0.9854 0.9896 1.0075 1.0083 0.9946 0.9770 0.9953 1.0195 1.0197 1.0003 0.9795 0.9854 1.0130
oleoyl glycine 0.9666 0.9961 0.9715 1.0148 0.9759 0.9626 1.0299 1.0416 1.0037 1.0615 1.0268 0.9867 0.9424 1.0141 0.9772 0.9280 0.9827 1.0005
ornithine 1.0164 1.0006 1.0019 1.0073 1.0014 0.9871 0.9997 0.9918 0.9998 0.9932 0.9890 0.9845 1.0207 1.0142 1.0016 0.9894 0.9890 1.0128
pantothenate 1.0155 0.9906 1.0130 0.9842 0.9939 0.9887 1.0150 1.0019 1.0200 0.9900 0.9996 0.9817 1.0150 1.0050 1.0102 0.9767 0.9928 1.0048
pantothenol 0.9874 0.9799 0.9607 1.0381 1.0070 1.0301 1.0080 0.9989 1.0096 0.9424 1.0476 1.0188 0.9909 0.9995 1.0172 0.9772 1.0447 0.8678
phenylacetylglutamine 1.0087 0.9898 1.0030 1.0069 0.9970 0.9895 1.0021 0.9888 1.0091 1.0051 0.9997 0.9833 1.0135 1.0011 1.0108 1.0135 1.0058 1.0125
phenylalanine 1.0021 0.9967 0.9979 1.0004 1.0005 0.9938 1.0024 0.9980 1.0040 1.0033 1.0047 0.9956 1.0010 0.9996 1.0004 0.9959 1.0042 1.0041
piperine 0.9699 1.0026 1.0357 0.9655 0.9911 0.9439 1.0222 0.9917 1.0552 0.9425 0.9920 0.9000 1.0438 1.0360 1.0629 1.0446 0.9678 0.9339
proline 1.0093 1.0015 0.9991 0.9919 0.9961 1.0009 0.9988 0.9972 1.0013 0.9864 0.9957 0.9962 1.0160 1.0116 1.0002 0.9845 0.9980 1.0108
proline-betaine 0.9857 0.9832 1.0123 1.0011 1.0247 0.9639 0.9863 0.9901 1.0146 1.0483 1.0363 0.9465 0.9882 0.9778 0.9962 1.0405 1.0373 0.9623
pseudouridine 1.0005 0.9939 0.9997 1.0004 0.9994 0.9879 0.9979 0.9990 1.0073 1.0097 1.0083 0.9901 1.0005 0.9995 0.9997 1.0028 1.0079 0.9957
quinine 1.0376 0.8163 NA 0.9539 1.3360 NA 0.8436 1.0097 NA 1.5033 1.2674 NA NA 0.6960 0.7304 NA 0.7004 NA
ribothymidine 1.0065 0.9964 1.0088 0.9973 0.9955 0.9907 1.0018 0.9990 1.0108 1.0043 1.0020 0.9883 0.9959 0.9997 1.0130 0.9823 0.9983 1.0070
SDMA 1.0018 0.9972 0.9992 0.9975 0.9954 0.9913 0.9974 1.0047 1.0082 1.0005 1.0005 0.9933 1.0059 1.0081 0.9991 0.9889 0.9969 0.9938
serine 1.0025 0.9961 0.9957 1.0049 0.9981 1.0021 0.9945 0.9985 1.0033 1.0030 0.9952 1.0002 0.9942 1.0072 1.0052 0.9866 1.0023 1.0156
serotonin 1.0452 0.9406 1.0045 1.0144 1.0060 0.9982 1.0402 0.9464 1.0227 1.0474 1.0450 1.0394 1.0639 0.9596 1.0152 1.0134 1.0079 1.0774
sphinganine 1.0063 0.9694 1.0048 1.0139 0.9986 0.9798 1.0177 0.9770 1.0093 1.0227 1.0182 0.9777 1.0137 0.9854 1.0127 0.9990 1.0470 1.0603
taurine 1.0069 0.9944 1.0021 1.0014 1.0065 0.9816 1.0038 0.9893 1.0095 1.0101 1.0125 0.9743 1.0011 0.9952 1.0081 0.9871 1.0093 1.0203
thiamine 1.0206 0.9860 1.0556 0.9712 0.9947 0.9743 1.0210 0.9835 1.0497 0.9456 0.9840 0.9679 1.0569 1.0205 1.0301 0.9582 0.9836 0.9979
threonine 1.0080 0.9974 1.0030 0.9891 0.9928 0.9977 0.9959 0.9996 1.0081 0.9958 0.9951 1.0041 1.0093 1.0092 1.0025 0.9778 1.0018 1.0175
threo-sphingosine 1.0050 0.9767 1.0010 1.0281 1.0046 0.9868 1.0057 0.9736 1.0179 1.0420 1.0184 0.9788 0.9944 0.9805 1.0002 0.9975 1.0413 1.0491
thyroxine 1.0097 0.9874 0.9971 1.0025 0.9916 1.0080 1.0045 0.9982 1.0067 1.0142 1.0005 1.0119 1.0146 0.9972 1.0060 0.9895 0.9905 1.0224
trigonelline 1.0308 0.9906 1.0102 0.9990 1.0128 0.9850 0.9876 0.9665 0.9733 1.0124 1.0014 0.9278 1.0839 1.0170 1.0058 1.0336 0.9898 1.0416
trimethylamine-N-oxide 1.0025 0.9767 1.0079 0.9972 1.0350 0.9749 0.9833 0.9806 1.0129 1.0138 1.0121 0.9928 1.0171 0.9974 0.9960 1.0156 1.0235 1.0051
tryptophan 1.0043 0.9992 0.9992 0.9979 0.9966 0.9907 1.0014 1.0009 1.0045 1.0001 0.9982 1.0005 1.0034 1.0063 1.0021 0.9876 0.9950 1.0060
Tryptophan_μM 1.0704 0.9696 0.9738 0.9571 0.9364 0.8144 1.0266 1.0129 1.0974 0.9685 1.0349 0.9754 1.0259 1.0910 1.0318 0.8645 0.9757 1.0647
tyrosine 1.0109 1.0000 0.9996 0.9963 1.0012 0.9966 0.9989 0.9967 1.0012 0.9974 1.0003 0.9954 1.0042 1.0069 0.9940 0.9852 0.9996 1.0124
urate 0.9957 0.9957 1.0055 1.0043 1.0014 0.9836 0.9897 0.9994 1.0133 1.0030 1.0024 0.9822 1.0014 1.0049 1.0054 0.9945 1.0057 0.9905
urobilinogen 1.1075 0.9513 0.9590 1.1051 1.0289 1.1135 0.9862 0.9783 1.1022 0.9749 0.9816 0.9424 1.0415 0.9350 0.9680 1.1126 0.9259 1.1644
urocanic acid 1.0230 0.9907 1.0008 1.0027 1.0125 0.9747 1.0201 0.9868 1.0110 0.9801 0.9751 0.9768 1.0200 1.0068 1.0049 1.0258 1.0251 0.9899
valsartan 0.9785 1.0374 0.7623 0.8254 1.4084 1.0441 0.9479 1.0770 0.2750 0.5685 1.3162 1.0391 1.2935 1.1046 0.5525 1.0785 1.2156 0.9766
warfarin NA NA NA NA 0.9969 0.5488 NA NA NA NA 0.9671 NA NA 1.1736 NA NA 1.1536 NA
xanthine 1.0091 0.9951 0.9930 0.9940 1.0089 1.0035 1.0222 0.9999 0.9788 1.0003 1.0064 0.9967 1.0005 0.9997 0.9826 0.9758 1.0091 1.0477
Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1Time point:baseline | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 | Nivolumab Dose (mg/kg):0.3
F2Time point:baseline | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 | Nivolumab Dose (mg/kg):10
F3Time point:baseline | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 | Nivolumab Dose (mg/kg):2
F4Time point:baseline | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- | Nivolumab Dose (mg/kg):0.3
F5Time point:baseline | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- | Nivolumab Dose (mg/kg):10
F6Time point:baseline | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- | Nivolumab Dose (mg/kg):2
F7Time point:week 4 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 | Nivolumab Dose (mg/kg):0.3
F8Time point:week 4 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 | Nivolumab Dose (mg/kg):10
F9Time point:week 4 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 | Nivolumab Dose (mg/kg):2
F10Time point:week 4 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- | Nivolumab Dose (mg/kg):0.3
F11Time point:week 4 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- | Nivolumab Dose (mg/kg):10
F12Time point:week 4 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- | Nivolumab Dose (mg/kg):2
F13Time point:week 9 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 | Nivolumab Dose (mg/kg):0.3
F14Time point:week 9 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 | Nivolumab Dose (mg/kg):10
F15Time point:week 9 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 | Nivolumab Dose (mg/kg):2
F16Time point:week 9 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- | Nivolumab Dose (mg/kg):0.3
F17Time point:week 9 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- | Nivolumab Dose (mg/kg):10
F18Time point:week 9 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- | Nivolumab Dose (mg/kg):2
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