Data for (Study ST001253)

(Analysis AN002079)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

MetaboliteF1F2F3F4
1-methyl-4-imidazoleacetate 1.0747 1.6866 0.7272 0.5695
1-methylhistamine 1.4781 0.9998 1.1973 0.5949
1-methylnicotinamide 1.7979 1.2018 0.6602 0.5637
1-ribosyl-imidazoleacetate 1.1030 0.7528 1.4682 0.8551
2-aminobutyrate 1.0268 0.8899 1.2543 0.9194
2-aminoheptanoate 1.2042 1.5938 0.6801 0.5943
2-butenoylglycine 0.8402 0.7183 1.1179 1.2504
2^-deoxycytidine 0.7482 0.5365 1.3588 1.3067
2-hydroxyglutarate 0.8970 1.1358 0.9980 0.9544
2-methylbutyrylcarnitine (C5) 1.1271 0.6509 1.1088 1.1378
2^-O-methylcytidine 0.4205 1.8983 0.6269 0.8529
2-oxoarginine 0.9094 0.6678 1.2220 1.1870
3-hydroxybutyrylcarnitine (1) 1.4185 1.1918 0.8249 0.7005
3-hydroxybutyrylcarnitine (2) 1.2232 1.1988 0.9312 0.7484
3-methoxytyrosine 0.6279 0.7956 1.3222 1.1935
3-methylcrotonylglycine 1.1910 0.4619 1.1466 1.2279
3-methylcytidine 0.6373 1.3437 1.1407 0.8582
3-ureidopropionate 0.9924 1.2233 1.0752 0.7808
4-acetamidobutanoate 1.2140 1.0492 1.1336 0.7521
4-guanidinobutanoate 1.3730 1.2382 0.8372 0.6833
4-hydroxybutyrate (GHB) 0.9437 1.6361 0.4503 0.8548
4-imidazoleacetate 1.1926 0.9458 1.0857 0.8764
5-aminovalerate 0.8842 1.0210 1.1195 0.9809
5-hydroxylysine 1.0261 1.1213 1.0621 0.8501
5-methyl-2^-deoxycytidine 0.9302 0.8436 0.9825 1.1775
5-methylcytidine 0.5644 0.7269 1.1467 1.3919
5-methylthioadenosine (MTA) 1.2128 0.7926 1.4834 0.7482
5-methylthioribose 0.5232 0.5870 1.3555 1.4032
7-methylguanine 0.6752 1.4145 0.9206 0.9109
acetylcarnitine (C2) 1.0020 0.9977 1.1402 0.9165
adenine 1.6604 0.7377 1.3943 0.5770
adenosine 5^-monophosphate (AMP) 0.6906 0.7123 1.8441 0.9093
adipoylcarnitine (C6-DC) 0.9539 0.9192 0.7587 1.2371
anserine 0.1766 0.5986 0.6149 2.0462
anthranilate 1.0752 1.0050 1.1758 0.8454
argininate 1.3892 0.7544 1.5202 0.6509
arginine 0.6199 0.7150 1.0845 1.4053
argininosuccinate 0.3720 1.3504 0.7662 1.2368
asparagine 0.9465 0.9391 1.1088 1.0155
aspartate 0.9274 1.1366 0.9123 0.9869
beta-alanine 0.5351 0.9291 1.2550 1.1827
betaine 0.7463 0.9234 1.3205 1.0211
biotin 1.2129 0.9634 1.4349 0.6406
butyrylcarnitine (C4) 1.8465 1.3988 0.5632 0.4351
carboxyethyl-GABA 1.2315 1.3240 0.6916 0.7869
carnitine 1.1547 0.8010 1.3226 0.8728
carnosine 0.3352 0.6063 0.7862 1.8422
choline 0.7489 1.3516 0.5970 1.1112
choline phosphate 0.7116 1.4224 1.0784 0.7881
citrulline 1.0917 1.1122 0.9612 0.8785
creatine 0.7596 1.1193 1.0218 1.0357
creatinine 0.7744 0.9778 1.0114 1.1463
cystathionine 0.5836 0.5646 1.6911 1.1835
cysteine 0.2613 0.8113 0.5529 1.8624
cysteine-glutathione disulfide 0.6688 1.0276 0.8541 1.2642
cysteine sulfinic acid 0.9593 0.6254 1.3497 1.1143
cysteinylglycine disulfide 0.6823 1.9915 0.8182 0.5065
cytidine 0.9500 0.8066 1.0320 1.1656
cytidine 5^-monophosphate (5^-CMP) 0.7304 0.4207 1.7678 1.1646
cytosine 0.5800 1.4872 0.9734 0.8781
deoxycarnitine 0.9480 0.8694 1.0139 1.1274
dimethylarginine (SDMA + ADMA) 0.7279 1.4787 0.7073 0.9559
dimethylglycine 1.0589 1.1052 1.2407 0.7361
dimethyl sulfone 1.3633 1.3518 0.8140 0.6122
ergothioneine 0.9303 0.8123 0.6804 1.3837
formiminoglutamate 1.0862 2.4242 0.2360 0.2673
gamma-glutamyl-alpha-lysine 0.6844 0.7686 1.2133 1.2465
gamma-glutamylcitrulline 1.3778 1.0396 0.9372 0.7793
gamma-glutamyl-epsilon-lysine 0.1507 0.3883 1.6010 1.6383
gamma-glutamylglutamate 0.6644 1.3203 0.8382 1.0423
gamma-glutamylglutamine 1.1332 0.9436 1.0992 0.9056
gamma-glutamylglycine 0.6133 0.8933 1.2400 1.1733
gamma-glutamylhistidine 0.9916 0.8724 1.4842 0.8166
gamma-glutamylisoleucine 1.1120 0.9198 1.1876 0.8844
gamma-glutamylleucine 1.4645 1.0206 1.0065 0.7008
gamma-glutamylmethionine 0.8607 0.5585 1.8244 0.9421
gamma-glutamylphenylalanine 1.1564 1.0225 1.1015 0.8273
gamma-glutamyltryptophan 1.1158 1.2988 0.8978 0.7528
gamma-glutamyltyrosine 0.8375 0.8567 1.3157 1.0228
gamma-glutamylvaline 1.0268 0.8585 1.1844 0.9865
glutamate 0.8874 1.1511 0.7217 1.1136
glutamine 1.0868 1.0175 0.9966 0.9360
glutarylcarnitine (C5-DC) 0.6978 1.6118 0.8424 0.7865
glutathione, oxidized (GSSG) 0.5687 1.3891 0.3679 1.3268
glycerol 3-phosphate 0.6320 1.5987 0.4333 1.0819
glycerophosphoethanolamine 0.8842 1.1963 0.6122 1.1451
glycerophosphorylcholine (GPC) 1.0166 1.1243 0.5994 1.1310
glycerophosphoserine 0.6461 1.4440 0.5181 1.1463
glycine 0.7614 0.8749 1.1426 1.1577
guanidinosuccinate 1.5078 1.6855 0.3926 0.5113
guanosine 0.0316 0.0222 4.6996 0.1435
guanosine 5^- monophosphate (5^-GMP) 0.0829 0.0829 2.6289 1.3066
hexanoylcarnitine (C6) 0.8185 1.1397 1.1837 0.8869
histamine 2.1772 0.9706 0.8446 0.4104
histidine betaine (hercynine) 0.4728 1.0105 0.3553 1.6948
homoarginine 0.4927 0.5705 1.1746 1.5432
homocitrulline 0.8950 1.5705 0.9208 0.6541
homostachydrine 0.6483 0.6771 1.6017 1.1082
hydroxyasparagine 0.8402 1.2288 0.9926 0.9173
hydroxymethylpyrimidine 0.9700 1.1019 1.5906 0.5821
imidazole propionate 1.7000 1.0690 0.5035 0.8227
indolelactate 1.4419 1.2252 0.7689 0.6933
indolepropionate 1.3744 1.0895 1.1002 0.6437
indolin-2-one 0.9069 1.1031 1.4842 0.6829
inosine 5^-monophosphate (IMP) 0.8563 0.8563 1.2895 1.0275
isobutyrylcarnitine (C4) 1.1054 0.8292 1.4334 0.8134
isoleucine 1.4087 1.0524 0.9165 0.7630
isovalerylcarnitine (C5) 1.4683 0.8845 1.0827 0.7618
kynurenine 1.3585 0.8476 1.0930 0.8510
leucine 1.5162 0.9469 0.9608 0.7563
lysine 0.9399 0.9157 0.9840 1.1131
malonylcarnitine 0.7398 1.3452 0.8957 0.9426
methionine 0.8459 0.7748 1.4757 0.9872
methionine sulfone 1.8211 1.2921 0.5656 0.5344
methionine sulfoxide 0.8311 0.9913 1.3355 0.9070
methyl indole-3-acetate 2.8050 0.5832 0.9100 0.3045
methylphosphate 1.1634 0.7638 0.7326 1.2514
N1-Methyl-4-pyridone-3-carboxamide 1.1950 1.7755 0.4275 0.6061
N1-methyladenosine 0.6052 1.7964 0.6436 0.8136
N1-methylinosine 0.6476 1.9047 0.4870 0.7955
(N(1) + N(8))-acetylspermidine 1.4254 1.4832 0.5115 0.6513
N2,N2-dimethylguanosine 0.2625 2.2103 0.4501 0.8042
N4-acetylcytidine 0.6410 2.1109 0.3808 0.6982
N6-carboxyethyllysine 0.5834 1.2576 0.5394 1.3203
N6,N6,N6-trimethyllysine 0.8256 0.8920 0.7089 1.3657
N-acetyl-1-methylhistidine 0.6190 1.1466 1.1698 1.0094
N-acetyl-3-methylhistidine 0.5881 0.5027 1.8664 1.1251
N-acetylarginine 0.8199 0.6686 1.4204 1.1209
N-acetylasparagine 0.6876 0.8402 1.1958 1.1978
N-acetyl-aspartyl-glutamate (NAAG) 0.5613 0.8037 1.5730 1.0765
N-acetylglucosamine/N-acetylgalactosamine 0.7993 1.2701 0.9706 0.9219
N-acetylglucosaminylasparagine 0.9364 0.9098 0.3282 1.5134
N-acetylputrescine 1.0592 1.2345 1.1920 0.6617
N-alpha-acetylornithine 0.3383 0.9194 0.8092 1.5760
nicotinamide 0.9523 0.9336 0.9918 1.0866
nicotinamide N-oxide 0.6002 0.5349 1.7748 1.1470
nicotinate ribonucleoside 0.4114 1.2916 0.4373 1.4575
N-methyl-GABA 1.1057 1.6969 0.6271 0.6028
N-methylproline 0.9361 0.9128 1.0833 1.0581
N-monomethylarginine 0.9149 1.1627 0.9515 0.9500
N-trimethyl 5-aminovalerate 1.0307 1.2480 0.6689 0.9819
ornithine 1.1845 1.3258 0.7971 0.7504
phenylacetylglycine 0.9530 1.2148 0.7421 1.0111
phenylalanine 1.0412 0.9499 1.0520 0.9841
phosphate 0.5054 0.9698 0.5063 1.6172
phosphoethanolamine 0.7458 0.7111 1.0774 1.3372
picolinate 1.5633 0.9018 0.9367 0.7785
pimeloylcarnitine/3-methyladipoylcarnitine (C7-DC) 0.7578 1.1600 1.0258 1.0018
pipecolate 1.1402 1.2832 0.7276 0.8527
pro-hydroxy-pro 0.6308 0.7715 1.1931 1.2885
proline 0.8620 0.9690 1.2033 0.9856
prolylglycine 1.4753 0.4425 1.2436 1.0146
propionylcarnitine (C3) 0.9597 0.7686 1.6138 0.8410
putrescine 0.9169 1.6922 0.6457 0.7087
pyridoxal 1.6414 0.6045 1.4193 0.6800
pyroglutamine 1.3720 1.0951 1.1237 0.6265
S-1-pyrroline-5-carboxylate 1.3186 1.1170 1.0636 0.6770
sarcosine 0.7292 0.9850 1.6186 0.8033
serine 1.0553 0.8546 1.1630 0.9853
serotonin 1.9022 0.2089 2.3018 0.3105
S-methylcysteine sulfoxide 1.6834 2.0012 0.2283 0.2520
S-methylmethionine 2.5646 0.3591 1.0736 0.5297
spermidine 1.7423 1.4040 0.3512 0.6207
stachydrine 0.8607 0.8156 1.5188 0.9199
suberoylcarnitine (C8-DC) 1.2003 1.0623 0.8284 0.9330
succinylcarnitine (C4-DC) 0.6873 1.2163 0.5090 1.3092
taurine 0.8245 1.0406 1.0780 1.0260
thioproline 0.4442 0.6665 0.8752 1.6751
threonine 0.9360 0.8076 1.2492 1.0428
tiglylcarnitine (C5:1-DC) 1.3472 0.8522 1.0198 0.8981
trans-4-hydroxyproline 0.8606 0.7503 1.2264 1.1475
trans-urocanate 1.9883 0.4284 1.3077 0.6797
trigonelline (N^-methylnicotinate) 0.9755 0.8955 1.3101 0.9122
trimethylamine N-oxide 2.5057 1.3227 0.3453 0.2312
tryptophan 1.2012 0.9114 1.1695 0.8485
tyrosine 0.8728 0.8160 1.1859 1.1120
uracil 0.7055 2.1232 0.4921 0.5829
urea 1.2271 0.7423 1.1794 0.9622
uridine 5^-monophosphate (UMP) 0.7750 0.7750 1.4726 1.0314
valine 1.6082 0.9425 0.9163 0.7313
Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1diabetes:db/db | time of day:ZT17
F2diabetes:db/db | time of day:ZT5
F3diabetes:db/m | time of day:ZT17
F4diabetes:db/m | time of day:ZT5
  logo