Data for (Study ST002031)
(Analysis AN003301)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
2^,3^-Cyclic CMP | 1.0156 | 0.7111 | 1.2189 | 0.9635 | 0.9298 | 1.1350 | 1.1302 | 0.9761 | 1.0894 | 0.9462 | 0.8335 | 1.0858 |
3^,5^-Cyclic AMP | 0.8617 | 0.9217 | 0.7820 | 0.8584 | 0.7195 | 1.5140 | 0.8475 | 0.8730 | 1.2080 | 1.1094 | 0.7892 | 1.7484 |
4-Acetamidobutanoate | 0.9808 | 1.0408 | 1.1419 | 0.9720 | 0.9897 | 1.0675 | 1.0486 | 0.9620 | 0.7940 | 0.8287 | 1.0153 | 1.1469 |
5-6-Dihydrothymine | 1.1073 | 0.8918 | 0.9425 | 0.9808 | 0.9214 | 1.2642 | 1.1112 | 0.9660 | 0.8355 | 0.7356 | 0.9816 | 1.2865 |
5-6-Dihydrouracil | 0.8483 | 1.3420 | 0.4312 | 0.8379 | 1.5667 | 0.8312 | 1.1529 | 0.9068 | 0.7701 | 0.5692 | 0.9908 | 1.8837 |
5-Guanidino-2-oxopentanoate | 0.8945 | 0.8592 | 0.9212 | 0.6425 | 0.6656 | 1.1220 | 1.2903 | 1.1293 | 0.8695 | 0.9544 | 1.0290 | 1.7457 |
5-Hydroxyindoleacetate | 1.0019 | 0.9918 | 0.9351 | 0.8130 | 1.0559 | 1.3271 | 0.8322 | 1.0282 | 0.7531 | 0.8022 | 0.8568 | 1.6917 |
5-Hydroxyisourate | 0.9928 | 1.0685 | 0.9658 | 1.0066 | 0.8376 | 1.1623 | 0.8856 | 0.9165 | 0.8449 | 1.0465 | 0.9077 | 1.4177 |
5-Oxoproline | 1.0444 | 0.9366 | 1.0046 | 0.9714 | 0.8625 | 1.1681 | 1.0029 | 0.8625 | 0.9978 | 1.0230 | 0.9147 | 1.2638 |
acetyl-carnitine (acyl-C2) | 0.9530 | 0.9593 | 0.9066 | 0.9969 | 0.9715 | 1.2293 | 0.9149 | 0.8537 | 0.9845 | 0.9752 | 0.8555 | 1.4956 |
Acetylcholine | 0.7655 | 0.5654 | 0.5844 | 1.1259 | 0.5844 | 1.3424 | 0.9109 | 0.8332 | 0.9578 | 1.1242 | 1.2871 | 2.1379 |
acyl-C18:2 (Linoleoyl-CoA) | 1.0592 | 0.8252 | 0.8981 | 0.9171 | 0.9161 | 1.3129 | 0.6305 | 0.9665 | 1.0506 | 0.8144 | 0.9440 | 1.8447 |
acyl-C20:4 | 0.9105 | 0.7191 | 0.8096 | 1.0748 | 0.7959 | 1.5678 | 0.6522 | 0.8988 | 0.9399 | 0.7865 | 0.8216 | 2.2641 |
acyl-C4-OH (Hydroxybutyrylcarnitine) | 0.9505 | 1.1954 | 0.7270 | 0.9759 | 1.2317 | 1.2653 | 0.7325 | 0.6529 | 0.9387 | 0.9293 | 0.7455 | 1.8037 |
acyl-C5:1 (Tiglylcarnitine) | 0.9123 | 1.3115 | 0.8106 | 0.6863 | 0.9270 | 0.9134 | 1.3690 | 1.1897 | 0.5520 | 0.9089 | 1.0040 | 1.4068 |
acyl-C5-OH (hydroxyisovalerylcarnitine) | 1.1097 | 0.7316 | 0.7518 | 1.2609 | 1.0213 | 1.1204 | 0.9468 | 0.8347 | 1.1232 | 0.8912 | 0.9351 | 1.3725 |
Adenosine | 0.9916 | 0.9444 | 1.0506 | 1.1872 | 0.9579 | 1.0618 | 0.9039 | 0.8756 | 0.9950 | 0.9687 | 1.0725 | 1.0000 |
Allantoate | 1.2341 | 0.9534 | 0.8004 | 0.8968 | 1.0891 | 0.8316 | 1.3167 | 0.9361 | 0.9088 | 0.8830 | 1.3040 | 0.7847 |
Anthranilate | 0.8722 | 0.7445 | 1.1160 | 0.6161 | 0.7335 | 1.3306 | 1.2139 | 0.9529 | 1.0581 | 0.7855 | 1.2860 | 1.3779 |
butanoyl-l-carnitine (acyl-C4) | 1.0693 | 0.8814 | 0.8706 | 0.8122 | 1.2093 | 1.2132 | 1.2413 | 0.8144 | 0.8403 | 0.6450 | 1.0866 | 1.3555 |
Carnosine | 1.0558 | 0.9072 | 0.9586 | 0.9220 | 0.8981 | 1.1253 | 0.8943 | 0.9882 | 0.8404 | 0.9908 | 0.9400 | 1.5594 |
Creatine | 1.0429 | 1.2922 | 0.8854 | 0.9523 | 0.9860 | 0.9041 | 1.0736 | 0.9191 | 0.9323 | 1.0076 | 0.9968 | 0.9930 |
Creatinine | 1.0139 | 1.0575 | 0.9678 | 0.8840 | 0.9313 | 0.9041 | 1.3314 | 0.9867 | 0.8926 | 0.8699 | 1.0753 | 1.0800 |
Cytidine | 0.9822 | 0.9941 | 0.8118 | 1.1009 | 0.8835 | 1.4555 | 0.7210 | 0.6993 | 1.0524 | 0.9691 | 0.6071 | 1.9169 |
Cytosine | 0.8518 | 0.8600 | 0.8159 | 0.8251 | 0.9318 | 1.6051 | 0.9060 | 0.8141 | 0.9095 | 0.8518 | 0.7368 | 2.0926 |
D-Glucosamine | 0.8174 | 0.7109 | 0.8366 | 1.0043 | 0.7258 | 1.3037 | 0.8678 | 1.0277 | 1.0203 | 1.1702 | 1.0324 | 1.6087 |
Dimethylglycine | 1.0194 | 1.3755 | 0.6639 | 1.0715 | 0.9232 | 0.8614 | 1.2116 | 1.0283 | 0.8539 | 0.8603 | 1.0656 | 1.0451 |
Dopamine | 1.0963 | 1.1684 | 0.9517 | 1.0211 | 1.0522 | 1.1311 | 0.8764 | 0.9917 | 0.7714 | 0.9880 | 0.8202 | 1.1074 |
Ectoine | 0.8477 | 0.6901 | 1.0367 | 0.5935 | 0.8499 | 1.1976 | 1.4339 | 1.0347 | 0.9183 | 0.8226 | 1.1931 | 1.4570 |
gamma-Glutamyl-gamma-aminobutyrate | 1.1197 | 1.5507 | 0.9354 | 0.9845 | 1.1256 | 1.0473 | 0.8108 | 0.9766 | 0.8662 | 0.7412 | 0.8911 | 0.9052 |
Glutathione disulfide | 0.9169 | 0.9327 | 0.9963 | 0.9062 | 0.9529 | 1.2664 | 0.9327 | 0.9175 | 0.8662 | 0.9128 | 0.9125 | 1.5752 |
g-Oxalo-crotonate | 0.5069 | 0.1942 | 0.5997 | 0.3332 | 1.0167 | 1.2729 | 1.3428 | 0.9125 | 1.5881 | 0.9943 | 1.6697 | 1.8582 |
Guanidinoacetate | 1.2263 | 0.7658 | 0.8679 | 1.0069 | 0.8776 | 0.9273 | 0.9719 | 0.9422 | 0.7591 | 0.8613 | 1.2089 | 1.6707 |
Guanine | 0.9586 | 1.0993 | 1.0717 | 1.0467 | 1.2877 | 1.1387 | 0.7600 | 0.8288 | 1.0450 | 1.0581 | 0.8750 | 0.7991 |
Hexadecenoyl-carnitine (acyl-C16:1) | 0.9465 | 1.1696 | 0.9597 | 1.2025 | 1.0346 | 1.5083 | 0.5589 | 0.8051 | 1.0302 | 0.6836 | 0.6862 | 1.5262 |
hexanoyl-L-carnitine (acyl-C6) | 1.1123 | 1.3689 | 0.7148 | 1.0736 | 1.1683 | 1.6402 | 0.6767 | 0.6260 | 0.5597 | 0.5893 | 0.6189 | 1.9540 |
Hydroxyindole-acetylglycine | 0.7415 | 0.9753 | 0.8998 | 0.5062 | 0.9456 | 1.0371 | 1.8517 | 1.0043 | 0.9091 | 0.8244 | 1.0349 | 1.2531 |
Hypoxanthine | 0.5072 | 0.2175 | 0.5918 | 0.3405 | 0.9375 | 1.4192 | 1.0466 | 0.8456 | 1.5495 | 0.8360 | 1.2878 | 2.9133 |
IMP | 0.8463 | 0.7297 | 1.1208 | 0.8897 | 1.1753 | 1.4284 | 0.7414 | 0.9911 | 1.0685 | 1.0229 | 0.7350 | 1.3308 |
Indole | 0.9302 | 0.6943 | 1.1034 | 0.7973 | 0.9083 | 0.7200 | 1.0993 | 1.1692 | 1.4272 | 0.7726 | 1.4414 | 1.0282 |
Indolepyruvate | 1.0647 | 0.5315 | 0.5743 | 0.4577 | 1.0829 | 1.3063 | 1.1094 | 1.4189 | 0.9729 | 1.1578 | 0.8692 | 1.4754 |
Indoxyl | 1.0455 | 0.6814 | 0.8261 | 0.7110 | 0.9797 | 0.9990 | 1.6421 | 1.3491 | 0.9224 | 0.8076 | 1.4457 | 0.4685 |
Inosine | 0.4163 | 0.1348 | 0.4453 | 0.2566 | 0.8193 | 1.4866 | 0.7332 | 0.8376 | 1.0746 | 0.5950 | 1.1389 | 4.1186 |
kynurenine | 0.8415 | 0.9103 | 0.5080 | 0.7054 | 0.8218 | 0.7786 | 1.6024 | 1.5955 | 0.8301 | 1.0823 | 1.2013 | 1.1109 |
L-Adrenaline | 1.1440 | 1.3703 | 0.9995 | 0.9823 | 1.0085 | 1.0057 | 0.8523 | 0.9803 | 0.9278 | 1.0353 | 0.7264 | 0.9416 |
L-alanine | 1.0223 | 0.8650 | 1.1139 | 0.7937 | 0.7863 | 0.9406 | 1.3302 | 1.1426 | 0.9299 | 0.9350 | 1.1625 | 0.9549 |
L-arginine | 0.6936 | 0.8745 | 0.9428 | 0.6312 | 0.7250 | 0.9896 | 1.1878 | 1.1656 | 1.1139 | 1.1041 | 1.1269 | 1.5847 |
L-asparagine | 0.8639 | 1.1882 | 0.6830 | 0.8114 | 1.1923 | 0.8625 | 1.2999 | 0.9341 | 0.8953 | 0.7152 | 0.9755 | 1.6972 |
L-aspartate | 1.0784 | 1.0668 | 0.6868 | 0.7107 | 0.6194 | 1.0904 | 1.7209 | 1.0110 | 0.7335 | 0.8977 | 0.9732 | 1.4473 |
L-Carnitine | 1.2838 | 0.9573 | 1.0112 | 1.0494 | 0.8688 | 1.0685 | 0.9564 | 0.9539 | 0.8953 | 0.9348 | 0.8393 | 1.2003 |
L-Citrulline | 1.2311 | 0.6758 | 0.9296 | 0.8616 | 0.8550 | 0.9828 | 1.3434 | 0.9393 | 0.9466 | 0.8975 | 1.1188 | 1.2599 |
L-cystine | 0.8757 | 1.3140 | 1.1818 | 0.8886 | 0.9335 | 0.7595 | 1.4077 | 1.0886 | 0.9219 | 0.8393 | 0.9465 | 0.7842 |
L-glutamate | 0.9457 | 0.8478 | 0.9806 | 0.8527 | 0.8856 | 1.4214 | 0.9389 | 0.8120 | 0.9494 | 0.9389 | 0.8391 | 1.7223 |
L-glutamine | 1.0558 | 0.9859 | 1.0830 | 0.9927 | 0.8521 | 1.0380 | 1.0180 | 0.9067 | 0.9307 | 1.0595 | 0.9754 | 1.1103 |
L-histidine | 0.9865 | 0.7119 | 0.9705 | 0.8747 | 0.7911 | 0.8161 | 1.1934 | 1.0785 | 1.0886 | 1.1097 | 1.1934 | 1.2540 |
L-Homocysteine | 1.1089 | 1.7710 | 0.3653 | 1.2802 | 0.9261 | 0.5965 | 0.6991 | 1.2276 | 0.9861 | 1.1568 | 1.1271 | 0.6908 |
L-leucine/isoleucine | 0.9340 | 0.9866 | 1.0089 | 0.9436 | 0.8838 | 1.0441 | 1.1859 | 0.8877 | 1.0520 | 0.8324 | 0.9788 | 1.3408 |
L-lysine | 0.8248 | 0.9547 | 0.9587 | 0.8094 | 0.8080 | 0.9438 | 1.1017 | 1.0385 | 0.9532 | 1.0617 | 1.1634 | 1.4658 |
L-methionine | 0.8856 | 0.6461 | 1.0177 | 0.7269 | 0.7184 | 1.0415 | 1.5489 | 0.9902 | 0.9815 | 0.7887 | 1.2230 | 1.5347 |
L-Methionine S-oxide | 0.9369 | 0.8781 | 0.9400 | 0.9996 | 0.9067 | 1.0119 | 1.3307 | 0.9829 | 1.0024 | 0.8872 | 1.1191 | 1.0063 |
L-octanoylcarnitine (acyl-C8) | 0.7562 | 0.8047 | 0.5882 | 0.6962 | 0.7314 | 3.1414 | 0.4038 | 0.4116 | 0.4923 | 0.6032 | 0.3691 | 3.3755 |
L-Palmitoylcarnitine (acyl-C16) | 0.9852 | 0.9723 | 0.9796 | 1.0539 | 0.9881 | 1.2851 | 0.6476 | 0.8931 | 0.9351 | 0.9173 | 0.8668 | 1.5788 |
L-phenylalanine | 1.1200 | 0.9594 | 1.0121 | 1.0168 | 0.9382 | 1.0004 | 1.1153 | 0.9066 | 0.9790 | 0.8913 | 0.9218 | 1.1684 |
L-proline | 1.0540 | 0.7989 | 0.9716 | 0.7214 | 0.7830 | 0.9101 | 1.3658 | 1.1479 | 1.0059 | 0.8773 | 1.1802 | 1.2312 |
L-serine | 0.9039 | 0.7143 | 0.9251 | 0.8161 | 0.7168 | 0.9446 | 1.1964 | 1.1292 | 1.0131 | 1.1191 | 1.3012 | 1.2787 |
L-threonine | 0.7126 | 0.8570 | 0.8464 | 0.7049 | 0.6697 | 0.8633 | 1.4633 | 1.1253 | 1.1329 | 0.9126 | 1.4344 | 1.3802 |
L-tryptophan | 0.9187 | 0.6856 | 1.0972 | 0.7962 | 0.9058 | 0.7467 | 1.1970 | 1.1768 | 1.3226 | 0.8533 | 1.3626 | 1.0027 |
L-tyrosine | 1.1721 | 0.5651 | 0.8548 | 1.0145 | 0.8416 | 0.7745 | 1.3962 | 0.9673 | 1.0925 | 0.9723 | 1.0458 | 1.4023 |
L-valine | 1.0072 | 0.8356 | 0.9253 | 0.8777 | 0.8605 | 0.9573 | 1.2544 | 1.0258 | 1.0720 | 0.8843 | 1.1189 | 1.2442 |
N-Acetylornithine | 1.1304 | 0.9418 | 1.0813 | 0.9931 | 1.0482 | 1.5533 | 0.9898 | 0.8015 | 0.7709 | 0.7853 | 0.7079 | 1.1884 |
NAD+ | 1.2266 | 0.9337 | 0.9455 | 1.0471 | 1.1698 | 1.2418 | 0.9641 | 0.8465 | 0.6748 | 0.8617 | 0.9040 | 1.1491 |
NADP+ | 1.0917 | 0.9659 | 0.9172 | 1.0091 | 0.9204 | 1.0517 | 1.0861 | 0.9781 | 0.8511 | 1.0284 | 1.0058 | 1.0810 |
N-formyl kynurenine | 1.0386 | 1.2617 | 0.8514 | 0.9575 | 0.9493 | 0.8954 | 0.8599 | 1.4848 | 0.5725 | 1.2034 | 0.7800 | 1.0749 |
Nicotinamide | 0.9183 | 0.9862 | 0.9810 | 1.0071 | 0.8520 | 1.2998 | 0.9374 | 0.8782 | 0.9091 | 0.9932 | 0.8390 | 1.4756 |
N-Methylethanolamine phosphate | 1.2163 | 0.6067 | 0.6652 | 0.6361 | 0.6766 | 0.6878 | 1.7354 | 1.2359 | 1.0609 | 1.0534 | 1.4795 | 0.9478 |
octenoyl-l-carnitine (acyl-C8:1) | 0.8981 | 0.7984 | 0.5288 | 0.9495 | 0.8209 | 2.1936 | 0.6531 | 0.8400 | 0.5752 | 0.5880 | 0.4127 | 2.9648 |
O-Decenoyl-L-carnitine (acyl-C10:1) | 0.9109 | 0.8370 | 0.5163 | 0.6976 | 0.6131 | 2.8227 | 0.4414 | 0.4830 | 0.4759 | 0.6199 | 0.4874 | 3.4875 |
O-dodecanoyl-carnitine (acyl-C12) | 1.6273 | 1.0185 | 0.7141 | 0.9385 | 1.1151 | 1.4050 | 0.5520 | 0.8169 | 0.8186 | 0.7972 | 0.6407 | 1.6497 |
O-dodecenoyl-carnitine (acyl-C12:1) | 1.5453 | 1.3663 | 0.7509 | 1.0708 | 1.0589 | 1.2316 | 0.8245 | 0.7572 | 0.6704 | 0.6737 | 0.6781 | 1.3831 |
O-octadecenoyl-L-carnitine (acyl-C18:1) | 1.1198 | 1.2773 | 1.0250 | 1.0706 | 1.0973 | 1.1131 | 0.5994 | 0.9399 | 0.8329 | 0.8389 | 0.7842 | 1.3352 |
Ornithine | 1.1442 | 0.9393 | 0.8576 | 0.9342 | 1.0474 | 0.9201 | 1.0924 | 0.9367 | 0.9500 | 0.7718 | 1.3477 | 1.0608 |
O-tetradecanoyl-L-carnitine (acyl-C14) | 1.2227 | 0.8940 | 0.9288 | 1.0580 | 1.0327 | 1.2906 | 0.6140 | 0.8191 | 0.9148 | 0.6824 | 0.7472 | 1.9732 |
Pantetheine | 0.9346 | 1.0141 | 1.0607 | 0.8190 | 0.9300 | 0.6976 | 1.1753 | 1.2612 | 1.1244 | 0.9480 | 1.1919 | 0.8350 |
Pantetheine 4--phosphate | 0.8521 | 0.8914 | 0.8924 | 0.8349 | 0.7416 | 1.2982 | 0.8400 | 1.0361 | 0.8962 | 1.0159 | 1.1747 | 1.6323 |
Pantothenol | 0.9460 | 1.2233 | 0.8576 | 1.0262 | 1.3611 | 1.3696 | 0.8344 | 0.7774 | 0.8036 | 0.7830 | 0.7339 | 1.3057 |
Phosphate | 1.1738 | 1.1971 | 1.1014 | 1.1063 | 1.0768 | 0.7449 | 0.9614 | 0.9282 | 1.0728 | 0.8902 | 0.9982 | 0.7043 |
propionyl-carnitine (acyl-C3) | 1.0850 | 0.7926 | 0.6902 | 0.6864 | 1.0289 | 1.4714 | 1.0201 | 0.7508 | 0.9284 | 0.7188 | 0.8335 | 2.2246 |
Putrescine | 0.9507 | 0.8024 | 1.0720 | 0.9319 | 0.9441 | 2.0067 | 0.5526 | 0.4340 | 0.7295 | 0.6983 | 0.5418 | 2.6024 |
Pyridoxamine 5^-phosphate | 0.9350 | 0.7384 | 0.7863 | 0.9312 | 1.0671 | 0.6861 | 1.5573 | 1.0040 | 1.1959 | 1.1329 | 1.2024 | 0.7531 |
S-Adenosyl-L-methionine | 0.8699 | 0.8683 | 1.0253 | 0.8205 | 0.7187 | 1.1837 | 1.0632 | 0.9192 | 0.9672 | 0.9769 | 1.0097 | 1.7135 |
S-Glutathionyl-L-cysteine | 0.9574 | 1.0100 | 0.9689 | 0.8919 | 0.8898 | 0.9952 | 1.1931 | 1.0082 | 0.9998 | 0.9689 | 1.0812 | 1.0443 |
Spermidine | 0.4088 | 0.2758 | 0.3825 | 0.4021 | 0.3135 | 3.9075 | 0.3397 | 0.2850 | 0.3068 | 0.4103 | 0.2930 | 5.4203 |
Spermine | 0.5908 | 0.4814 | 0.5102 | 0.6807 | 0.4189 | 2.6251 | 0.6951 | 0.8283 | 0.5332 | 0.8218 | 0.5507 | 3.7131 |
Sphingosine | 1.1677 | 0.9267 | 1.1792 | 1.1690 | 0.8837 | 1.0958 | 0.7119 | 1.2075 | 0.8783 | 0.8135 | 1.0240 | 0.8980 |
Taurine | 0.9851 | 0.9781 | 1.1179 | 0.8613 | 1.0962 | 1.4843 | 0.7753 | 0.6600 | 0.9770 | 0.9222 | 0.7991 | 1.4236 |
Tetradecenoyl Carnitine (acyl-C14:1) | 1.2009 | 1.4215 | 0.8660 | 1.1065 | 1.2719 | 1.0783 | 0.6512 | 0.9136 | 0.7237 | 0.6856 | 0.6978 | 1.4097 |
trans-4-Hydroxy-L-proline | 0.9489 | 0.7399 | 0.9130 | 0.7326 | 0.7996 | 0.9489 | 1.3566 | 1.2039 | 1.0456 | 0.9257 | 1.1588 | 1.2948 |
Xanthine | 0.7146 | 0.3590 | 0.8355 | 0.4697 | 1.1416 | 1.7396 | 0.9678 | 0.7847 | 1.2017 | 0.8666 | 1.2374 | 1.9026 |
Factors:
F1 | Treatment:IV iron | Radiation Dose:Gy10 |
F2 | Treatment:IV iron | Radiation Dose:Gy11 |
F3 | Treatment:IV iron | Radiation Dose:Gy7 |
F4 | Treatment:IV iron | Radiation Dose:Gy8 |
F5 | Treatment:IV iron | Radiation Dose:Gy9 |
F6 | Treatment:IV iron | Radiation Dose:no irradiated |
F7 | Treatment:Saline | Radiation Dose:Gy10 |
F8 | Treatment:Saline | Radiation Dose:Gy11 |
F9 | Treatment:Saline | Radiation Dose:Gy7 |
F10 | Treatment:Saline | Radiation Dose:Gy8 |
F11 | Treatment:Saline | Radiation Dose:Gy9 |
F12 | Treatment:Saline | Radiation Dose:no irradiated |