Data for (Study ST002034)

(Analysis AN003307)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8F9F10F11F12
10-Formyldihydrofolate 0.4653 1.8027 0.8421 0.9020 1.6566 1.5276 0.5905 0.9219 1.2832 0.4605 0.6295 1.0807
10-Formyltetrahydrofolate 0.5243 1.5600 0.7954 1.2382 1.5489 2.2203 0.5825 0.3663 0.9674 0.4735 0.6863 1.4026
3-methyldioxyindole 0.8678 1.5116 1.1356 0.8126 1.4807 0.6315 0.5522 0.6607 2.5968 0.4279 0.9460 0.5279
4-Acetamidobutanoate 0.8353 1.4140 0.8563 1.0621 1.1869 1.1028 0.7923 0.7213 1.3231 0.7527 0.8356 1.2533
5-10-Methenyltetrahydrofolate 0.7733 1.2651 0.6100 0.5818 1.5936 2.2556 0.7307 0.7631 0.4704 0.7072 0.9325 1.6435
5-6-Dihydrothymine 0.7975 0.7554 1.0068 0.8550 0.7840 1.1071 0.6702 2.6848 0.7369 0.9074 0.7147 0.9364
5-6-Dihydrouracil 0.5474 0.7726 0.6662 1.2042 1.0663 0.7123 0.6125 3.2656 1.0894 0.5381 0.5994 0.8580
5-Hydroxyisourate 0.8148 0.7422 1.0398 0.6048 1.3510 1.8591 0.8728 1.0291 0.8292 0.7870 0.9322 1.3444
(5-L-Glutamyl)-L-glutamine 1.0412 0.8305 0.8944 1.1700 1.1934 1.3975 0.8847 0.8621 0.9473 0.8512 0.7196 1.3464
5-Oxoproline 0.5987 1.7446 0.8378 0.8282 1.7250 1.8108 0.6555 0.5265 1.0547 0.6619 0.6120 1.1468
5-Phosphoribosylamine 0.7949 0.4941 0.9396 0.8766 0.6015 1.2732 1.0791 1.4214 0.6189 1.4183 0.8005 1.8255
5^-Phosphoribosyl-N-formylglycinamide 0.7960 1.0224 0.8444 0.9131 1.2681 1.4895 0.8099 0.7616 1.4697 0.6048 0.9543 1.3223
6-Hydroxykynurenic acid 1.0440 1.2254 0.7992 1.1915 0.4985 0.5145 0.9404 2.0629 1.0508 1.2761 0.8072 0.3780
Acetylcholine 0.7332 1.5591 1.4093 1.6299 1.3241 0.7851 0.5528 0.7056 0.8419 0.7855 0.7098 0.8614
acyl-C12 (O-dodecanoyl-carnitine) 0.8528 0.6952 0.7989 1.0421 1.1220 1.4536 0.8198 0.9217 0.9726 0.9763 0.7640 1.8329
acyl-C2 (acetyl-carnitine) 0.9436 1.1634 1.0075 1.0512 1.0271 1.1027 0.8133 1.0150 0.9858 0.9665 1.0065 0.9187
acyl-C3 (propionyl-carnitine) 0.6530 0.9427 0.8583 0.7908 1.1210 1.8406 0.7664 1.3368 0.9124 0.6999 0.7456 1.6039
acyl-C4 (butanoyl-l-carnitine) 1.0376 1.2799 1.1206 1.3730 1.1556 0.7311 0.7938 0.6744 1.0339 1.1049 0.8760 0.7152
acyl-C4-DC 1.1493 1.3312 0.9566 1.1819 1.1780 0.6468 0.9253 0.9098 1.1958 0.9837 0.7945 0.6448
acyl-C4-OH (Hydroxybutyrylcarnitine) 0.7314 0.4268 0.7077 0.9232 1.5315 0.5584 0.2941 0.6070 0.3023 0.7987 1.8695 3.4166
acyl-C5:1 (Tiglylcarnitine) 0.8872 1.3184 0.6892 1.2203 1.2491 1.1190 0.8770 0.8821 0.9947 0.9616 0.8472 0.9713
acyl-C5 (isovalerylcarnitine) 0.7930 1.4282 0.8261 1.0756 0.8811 1.0626 0.8174 0.8488 1.1146 1.2142 0.9546 1.0241
acyl-C5-OH 1.0195 1.0587 0.9325 1.2898 1.2466 1.0487 0.7738 0.9773 0.8727 0.8941 0.8722 0.9980
acyl-C6-DC 1.1182 1.0102 0.9779 1.2349 1.1253 0.7577 0.9838 1.0742 1.1632 0.8751 0.8537 0.7625
acyl-C6 (hexanoyl-l-carnitine) 0.8397 1.1494 0.9172 1.1728 1.0595 1.0741 0.8053 1.0158 1.0612 1.0555 0.9336 0.9289
acyl-C8:1 (octenoyl-l-carnitine) 1.0128 1.0238 0.9181 1.1082 0.9165 1.0005 0.8832 1.0826 1.0317 1.1331 0.8673 1.0357
Adenosine 1.3214 0.5196 0.8420 1.0472 0.8203 0.6286 1.1734 1.3010 0.8217 1.3197 1.0761 1.0237
AMP 0.6218 0.7285 0.5666 0.3241 0.9631 1.8787 0.9921 1.3768 0.8003 1.1491 1.2033 1.6640
Anthranilate 0.8133 0.7443 0.8058 0.9280 0.9455 0.7697 0.7309 2.0795 0.9471 1.2092 0.8206 1.1868
Argininosuccinate 0.9981 0.7115 0.8496 0.8973 0.9129 1.2536 0.6818 0.9915 1.2066 0.9756 0.6204 2.1693
Choline 0.9521 0.6855 1.0773 0.8985 0.6980 1.2999 0.8735 1.1356 0.9937 1.1811 1.2812 0.9777
Creatine 0.2126 0.1895 0.7534 0.5225 0.8050 4.6921 0.1621 2.3549 0.2246 0.7992 1.1474 0.6501
Creatinine 0.4878 0.3123 0.5577 0.5014 0.8297 1.0257 0.3283 5.2988 0.4998 0.5084 0.8014 0.6924
Cytidine 1.2651 0.3962 1.1372 0.9570 0.8843 1.0616 1.3730 0.8624 0.4825 0.8142 0.9219 1.9419
Cytosine 0.9554 0.5414 0.9859 0.9289 0.7074 2.3301 1.3194 0.6943 0.8581 0.5994 1.0708 1.3081
Dimethylglycine 0.7038 1.2955 0.8464 1.0015 1.4271 1.3280 0.8726 0.7151 1.4117 0.8287 0.6589 1.0731
Dopamine 0.9793 1.2618 1.0193 1.1508 1.0454 1.0551 0.7436 0.8915 1.0637 0.8846 0.9061 1.0283
Ectoine 0.6747 0.5891 0.9469 0.6369 1.1772 1.4142 0.6749 1.8812 1.2052 0.7466 0.6204 1.6956
gamma-Glutamyl-gamma-aminobutyrate 0.9254 1.0087 0.7130 0.9663 1.3409 1.4610 0.7563 0.8894 1.0029 0.7437 0.8050 1.6001
gamma-Glutamyl-Se-methylselenocysteine 0.1566 0.4369 0.1219 0.2010 1.6128 1.7378 1.6014 0.1569 0.4463 0.1405 0.3292 4.7387
gamma-L-Glutamyl-D-alanine 0.7116 1.4364 0.6715 0.6917 1.5748 1.6716 0.8919 0.6784 1.3562 0.4753 0.7421 1.3801
glycine 1.0426 0.8166 1.2042 0.8565 0.8294 0.8676 1.0204 1.1084 1.1084 1.3394 0.9916 0.7624
Guanine 1.3458 0.2394 1.0815 1.1404 0.8266 0.7940 1.4448 1.2449 0.6454 1.3773 0.8012 0.9333
Indole-3-acetaldehyde 1.0659 1.0430 1.0929 0.8471 1.1238 0.9967 0.6784 0.8128 1.0254 1.1624 0.9451 1.2636
Indolepyruvate 0.4319 0.3714 0.5705 0.5489 0.3249 0.6710 1.3876 1.4599 1.8679 1.6783 1.1981 1.7466
Indoxyl 0.5628 1.7929 0.5477 0.7149 1.1837 1.2043 1.1200 0.8582 1.2407 0.6615 1.1421 1.0754
L-Adrenaline 1.0294 0.9377 1.0271 0.9399 0.9181 0.7141 0.9474 1.7522 0.8332 1.1630 0.8903 0.6962
L-alanine 1.0360 0.8882 1.0483 0.8008 0.9882 1.5753 0.7859 0.9884 1.1423 0.9767 0.9763 0.9215
L-arginine 1.5400 0.1917 1.4298 1.0280 0.4917 0.3400 0.3670 2.0590 0.6713 2.7107 0.5255 0.4747
L-Carnitine 0.8868 1.3280 0.9320 1.2643 0.8637 1.0977 0.7768 0.9254 1.1275 1.0243 1.0866 0.6650
L-Citrulline 1.0306 1.3295 0.9444 1.0581 1.0496 0.5995 0.7703 0.9918 1.6257 1.3655 0.7758 0.3802
L-glutamate 0.5631 1.9234 0.7753 0.8987 1.7555 1.7904 0.6137 0.4740 1.0796 0.6277 0.6017 1.0885
L-histidine 1.0448 0.5637 1.2680 0.9272 0.7538 1.3632 0.7444 1.5446 0.6457 1.1998 0.8047 1.1773
L-lysine 0.8553 1.0968 0.9180 1.1209 0.8718 1.1479 0.6739 1.1133 1.6062 1.2845 0.7526 0.6371
L-methionine 0.9981 0.7855 0.9571 0.7932 1.0085 1.1337 0.7883 1.3185 1.5379 1.0868 0.8329 0.8672
L-Methionine S-oxide 0.9381 0.5374 1.0512 0.8106 0.7175 1.5445 0.8432 1.4560 0.9775 1.0158 0.7528 1.5747
L-tryptophan 0.8938 0.5701 0.9699 0.4957 0.8916 1.1835 0.8333 2.1546 0.8418 1.1301 0.9811 1.0745
N-formyl kynurenine 1.1181 0.8546 0.9671 0.9182 0.8731 0.9993 1.0066 1.0122 1.0829 1.0685 1.0338 1.1025
Nicotinamide 0.9001 1.5800 0.8273 0.6108 1.2360 1.4728 0.4400 1.5076 1.0260 0.6022 0.9958 0.8764
Ornithine 0.6487 0.9353 0.9998 0.9992 0.9378 1.2619 0.8015 1.1899 1.4012 1.5208 0.6535 0.7288
Phosphoserine 0.5661 2.1840 0.7901 0.9455 1.7650 1.4158 0.6215 0.4949 1.2677 0.5326 0.6693 0.8552
Putrescine 0.5001 0.2431 0.9543 1.6376 0.4479 0.8230 0.3439 1.5862 0.5118 3.7155 0.6418 0.3273
Pyridoxal 1.0880 0.9429 0.8838 0.9907 0.9427 1.1100 0.8896 1.0044 1.1059 0.9920 1.0614 1.0397
Spermidine 1.3430 0.7664 0.8090 0.9863 0.6562 0.2968 0.6694 1.7460 1.6142 2.0636 0.6435 0.2350
Urate 1.0180 0.3277 1.3879 0.8505 0.4764 0.4858 0.7593 1.5642 1.0352 1.3367 2.1402 0.4028
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Factors:

F1Treatment:IV iron | Radiation Dose:Gy10
F2Treatment:IV iron | Radiation Dose:Gy11
F3Treatment:IV iron | Radiation Dose:Gy7
F4Treatment:IV iron | Radiation Dose:Gy8
F5Treatment:IV iron | Radiation Dose:Gy9
F6Treatment:IV iron | Radiation Dose:no irradiated
F7Treatment:Saline | Radiation Dose:Gy10
F8Treatment:Saline | Radiation Dose:Gy11
F9Treatment:Saline | Radiation Dose:Gy7
F10Treatment:Saline | Radiation Dose:Gy8
F11Treatment:Saline | Radiation Dose:Gy9
F12Treatment:Saline | Radiation Dose:no irradiated
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