Data for (Study ST002068)
(Analysis AN003370)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1-Methyladenosine | 0.5073 | 0.8088 | 1.1976 | 0.8373 | 0.7581 | 1.2720 | 0.8052 | 1.1851 | 0.7285 | 0.9226 | 1.0699 | 1.9518 |
| 1-Methylnicotinamide | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 2-Hydroxycaproic acid | 0.7739 | 1.0825 | 0.9056 | 1.0354 | 1.1309 | 1.2442 | 0.8317 | 1.1677 | 0.6459 | 0.8831 | 1.1241 | 1.1789 |
| 2-Hydroxyvaleric acid | 0.3378 | 0.8109 | 1.0744 | 1.2197 | 1.3046 | 1.3399 | 0.3918 | 0.8471 | 0.4636 | 1.2029 | 1.4600 | 1.3030 |
| 2-Ketobutyric acid | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 2-Oxo-4-methylthiobutanoic acid | 1.0290 | 1.2632 | 0.7710 | 0.4204 | 0.3684 | 1.9891 | 0.6718 | NA | NA | 0.3591 | NA | 3.4705 |
| 3-Hydroxybutyric acid | 0.7615 | 1.2350 | 1.0754 | 0.7037 | 1.3506 | 0.9672 | 0.9078 | 1.3051 | 0.4561 | 0.8612 | 1.1261 | 1.2705 |
| 3-hydroxyhexadecanoic acid | 1.2667 | 0.8036 | 0.7004 | 1.2937 | 0.6980 | 1.0478 | 0.7671 | 1.1743 | 0.5079 | 0.8804 | 1.5048 | 1.0554 |
| 3-Hydroxymethylglutaric acid | 1.1660 | 1.5738 | 0.8146 | 1.2353 | 1.3395 | 1.0331 | 0.6937 | 0.9933 | 0.5245 | 0.9225 | 0.9068 | 0.7125 |
| 3-Indolepropionic acid | 0.6565 | 0.8444 | 1.5118 | 1.6532 | 1.2531 | 1.9188 | 0.6227 | 0.8020 | 0.5716 | 0.5240 | 0.8627 | 1.0545 |
| 3-Methylhistidine | 0.9965 | 1.4110 | 1.3530 | 1.5787 | 1.5590 | 0.8969 | 0.6251 | 1.4222 | 0.4817 | 0.7940 | 0.8762 | 0.3662 |
| 3-Methylthiopropionic acid | 0.6593 | 1.0753 | NA | 0.5705 | 0.8485 | 1.5557 | 0.7346 | 0.7896 | NA | 0.9500 | 0.4510 | 2.8146 |
| 3-Phosphoglyceric acid | 2.2283 | 1.0002 | 0.5488 | 0.5833 | 0.7738 | 0.9876 | 0.8724 | 2.7077 | 0.2644 | 0.5422 | 0.7767 | 0.4499 |
| 4-Acetamidobutanoic acid | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 4-Hydroxyproline | 0.9375 | 1.4093 | 1.3483 | 1.3530 | 1.6022 | 1.9133 | 0.4152 | 0.5770 | 0.4863 | 0.6482 | 0.6844 | 0.6266 |
| 4-Pyridoxic acid | 1.5941 | 2.7100 | 0.2366 | 1.2839 | 2.5255 | 1.8530 | 0.2276 | 0.4326 | 0.1210 | 0.2734 | 0.3202 | 0.1370 |
| 5-Methoxytryptophan | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 5^-Methylthioadenosine | 0.6254 | 1.2425 | 0.7881 | 1.2083 | 1.3399 | 1.2145 | 0.7240 | 1.4722 | 0.9229 | 0.8886 | 0.9090 | 0.9459 |
| 5-Thymidylic acid | NA | NA | 0.9974 | NA | NA | 0.9179 | 0.4797 | 1.9266 | 1.1827 | NA | NA | 0.7718 |
| 6-Phosphogluconic acid | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 6-Phosphonoglucono-D-lactone | 1.3120 | 0.8017 | 0.5850 | NA | NA | 0.9733 | 0.7714 | 1.1739 | NA | NA | 0.9857 | NA |
| 7-Methylguanosine | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Acetylcholine | 1.0406 | 1.3596 | 1.7310 | 1.0837 | 1.1438 | 1.9413 | 0.4949 | 0.7638 | 0.9597 | 0.4443 | 0.7923 | 0.5476 |
| Acetyl-CoA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Acetylcysteine | 0.3776 | 0.6118 | 3.2815 | 0.3297 | 0.9504 | 3.7990 | 0.3528 | 0.4872 | 0.5109 | 0.4548 | 0.5139 | 0.5777 |
| Adenine | 0.3926 | 0.3400 | 1.5025 | 0.3717 | 0.4453 | 0.5388 | 1.1707 | 1.5026 | 1.6388 | 1.7609 | 1.2387 | 1.2215 |
| Adenosine | 0.0286 | 0.1697 | 2.2404 | 0.2893 | 0.0693 | 0.6009 | 0.6548 | 1.2805 | 2.3264 | 2.0153 | 0.7308 | 1.8996 |
| Adenosine monophosphate | 0.1178 | 0.4399 | 1.7994 | 0.3505 | 0.4109 | 0.5498 | 0.6124 | 2.3986 | 2.8259 | 1.0653 | 1.3114 | 1.1993 |
| Adenosine phosphosulfate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Adenosine triphosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| ADP | 0.2477 | 0.2753 | 1.5633 | 0.4255 | 0.3861 | 1.1203 | 0.7585 | 2.6303 | 2.7984 | 0.7724 | 1.1692 | 0.9967 |
| ADP-glucose | NA | NA | 1.2025 | NA | NA | 1.1308 | NA | 0.8643 | 1.4121 | NA | 0.5260 | NA |
| AICAR | 0.7213 | 1.2657 | 4.7680 | 0.7560 | 0.8934 | 1.3929 | 0.3197 | 0.9035 | 0.4127 | 0.2544 | 0.7697 | 0.4137 |
| Allantoin | 0.9249 | 1.2902 | 1.7678 | 0.8388 | 1.1020 | 1.2224 | 0.7627 | 1.2728 | 0.7053 | 0.7265 | 0.9792 | 0.7360 |
| Aminoadipic acid | 1.5621 | 1.5822 | 1.0663 | 2.2130 | 2.1809 | 1.5382 | 0.3399 | 0.3733 | 0.2374 | 0.2600 | 0.3852 | 0.2582 |
| Arachidonic acid | 0.8350 | 1.4779 | 0.2378 | 0.8211 | 1.4618 | 0.9489 | 1.4456 | 2.1068 | 0.0751 | 1.0025 | 1.2674 | 0.4290 |
| Argininosuccinic acid | 1.9343 | 1.2959 | 1.6179 | 0.7052 | 1.2603 | 1.0411 | 0.7058 | 1.1469 | 0.3871 | 0.4713 | 0.7776 | 0.4744 |
| Ascorbic acid | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Asymmetric dimethylarginine | 1.1223 | 0.8358 | 1.8296 | 0.8930 | 0.8524 | 1.0412 | 0.9164 | 1.0008 | 1.0862 | 0.8213 | 0.8470 | 0.9601 |
| Betaine | 1.1498 | 1.3973 | 1.2671 | 1.2839 | 1.3620 | 1.3311 | 0.8382 | 0.9713 | 0.4780 | 0.7055 | 0.7169 | 0.6259 |
| Butyrylcarnitine | 0.3597 | 0.5465 | 2.1476 | 0.6139 | 0.6837 | 0.6483 | 0.4703 | 1.6155 | 2.5901 | 0.6746 | 1.0358 | 1.5972 |
| Caprylic acid | 0.7705 | 1.1608 | 1.2806 | 0.9194 | 1.1707 | 1.3191 | 0.6880 | 1.2238 | 0.7850 | 1.1090 | 0.6623 | 0.9701 |
| Carnosine | 0.7901 | 1.2864 | 1.8597 | 1.5918 | 2.0144 | 2.0452 | 0.2090 | 0.3599 | 0.2814 | 0.6191 | 0.4727 | 0.5300 |
| CDP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| CDP-Ethanolamine | 0.1909 | 0.2013 | 3.0128 | 0.2144 | 0.1563 | 0.7074 | 0.5466 | 1.1493 | 4.4708 | 0.6830 | 0.6504 | 1.3208 |
| Cholesterol sulfate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Cholic acid | 0.6364 | 0.7420 | 4.2166 | NA | 1.2427 | 1.8211 | 0.2476 | 1.2298 | 0.1608 | 0.6742 | 0.2061 | 0.2991 |
| Choline | 1.0898 | 1.3827 | 0.3213 | 1.3455 | 1.4078 | 1.1039 | 0.8572 | 1.1708 | 0.2263 | 0.9488 | 1.1366 | 0.7643 |
| cis-Aconitic acid | 0.6194 | 1.4806 | 2.0959 | 0.6259 | 1.5072 | 1.3452 | 0.4107 | 1.5409 | 0.5391 | 0.5544 | 0.9280 | 0.8591 |
| Citicoline | 0.1657 | 0.2227 | 3.0509 | 0.3031 | 0.1488 | 0.5770 | 0.4938 | 0.9401 | 4.4678 | 0.8725 | 0.5052 | 1.4544 |
| Citric acid | 0.6624 | 1.9329 | 0.6487 | 0.8302 | 1.9935 | 0.9098 | 0.3561 | 2.0671 | 0.2065 | 0.6173 | 1.3902 | 0.6394 |
| Citrulline | 1.0025 | 1.3757 | 1.3492 | 1.0056 | 1.0557 | 1.0107 | 0.8433 | 1.5431 | 0.9473 | 0.6961 | 0.9192 | 0.7066 |
| Coenzyme A | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Creatine | 0.8082 | 0.9053 | 1.0492 | 0.9667 | 0.9809 | 1.0655 | 0.9944 | 1.2529 | 1.1000 | 1.0039 | 1.0153 | 1.0097 |
| Creatinine | 0.7273 | 0.9199 | 0.8221 | 0.9481 | 0.9370 | 1.0960 | 1.1719 | 1.4030 | 0.7773 | 1.0501 | 1.2794 | 0.9562 |
| Cyclic AMP | 0.2285 | 0.1837 | 2.4844 | 0.1162 | NA | 0.8145 | 0.7750 | 0.2646 | 0.5268 | 0.2207 | 0.1843 | 2.9018 |
| Cytidine | 0.9726 | 1.2692 | 1.0385 | 1.1856 | 1.2598 | 1.3025 | 0.7806 | 1.2931 | 0.4303 | 0.8293 | 0.8953 | 0.8085 |
| Cytidine monophosphate | 0.4314 | 0.4462 | 2.2520 | 0.4421 | 0.3379 | 0.6906 | 1.4977 | 2.4615 | 1.0516 | 1.1554 | 1.1828 | 0.9058 |
| Cytidine triphosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Cytosine | 0.9786 | 0.9440 | 0.9792 | 0.9246 | 1.0047 | 1.0587 | 0.8870 | 1.1780 | 0.4343 | 0.9376 | 1.4237 | 1.0598 |
| D-2-Hydroxyglutaric acid | 1.0748 | 1.1421 | 2.1438 | 0.7612 | 1.5626 | 1.1598 | 1.0289 | 0.8698 | 0.9529 | 0.5602 | 0.5999 | 0.5651 |
| dCDP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| dCMP | 0.1864 | NA | NA | 0.5434 | NA | 1.1347 | 0.4418 | 1.9234 | 0.5202 | 1.6023 | 1.1374 | 0.3741 |
| dCTP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Deoxyadenosine | 0.1878 | 0.2369 | 3.0051 | 0.2545 | 0.1990 | 1.9916 | 1.1268 | 1.2473 | 1.9670 | 0.6919 | 0.7287 | 1.3493 |
| Deoxyadenosine monophosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Deoxyadenosine triphosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Deoxyinosine | 0.7920 | 0.8827 | 0.5245 | 0.6041 | 0.7634 | 1.1112 | 0.9520 | 0.5934 | 0.8054 | 0.5819 | 0.4333 | 3.6188 |
| Deoxyribose 5-phosphate | 1.4465 | 1.2871 | 0.3870 | 0.6730 | 1.3058 | 0.5458 | 0.8434 | 1.1738 | NA | 0.1668 | 1.4157 | 1.3200 |
| Deoxyuridine | 1.0140 | 0.9580 | 0.6966 | 0.6863 | 0.8920 | 1.1660 | 1.0301 | 1.2159 | 0.7216 | 0.7605 | 1.0597 | 1.6439 |
| D-Erythrose 4-phosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| D-Fructose | 1.2341 | 1.7241 | 0.3279 | 0.7829 | 2.1484 | 0.8874 | 0.5174 | 0.6558 | 0.2585 | 0.6973 | 1.6936 | 0.5175 |
| dGDP | 0.2373 | 0.3162 | 1.4353 | 0.4284 | 0.3553 | 1.1464 | 0.7323 | 2.7435 | 2.8733 | 0.8034 | 1.1314 | 0.9600 |
| D-Glucose | 1.2424 | 1.0458 | 0.5132 | 0.4896 | 1.6240 | 0.4238 | 1.4137 | 1.0338 | 0.4243 | 0.6730 | 2.0804 | 0.7043 |
| D-Glucuronic acid | 0.9953 | 1.3731 | 1.4294 | 0.8303 | 0.9569 | 1.0141 | 0.8427 | 0.9849 | 0.7129 | 0.7631 | 0.9559 | 1.2797 |
| D-Glyceraldehyde 3-phosphate | 0.2483 | 0.5715 | 0.5420 | 0.3740 | 0.3529 | 0.6569 | 1.5268 | 1.6925 | 2.7812 | 0.9462 | 1.4840 | 1.3725 |
| Dimethylglycine | 0.6854 | 0.9238 | 0.0871 | 1.0048 | 0.9744 | 0.3788 | 2.1560 | 1.7251 | 0.1534 | 1.5940 | 1.5942 | 0.6466 |
| D-Ribose | 1.6233 | 1.8641 | 0.0731 | 1.3208 | 2.5122 | 1.1577 | 0.6263 | 0.6089 | 0.0425 | 0.5682 | 0.6650 | 0.3860 |
| D-Ribose 5-phosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| D-Ribulose | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| D-Ribulose 5-phosphate | 0.9939 | 1.3557 | 0.3653 | 1.0232 | 1.1939 | 1.2775 | 1.3988 | 1.7669 | 0.1530 | 0.5008 | 1.2173 | 0.9431 |
| D-Sedoheptulose 7-phosphate | 2.2403 | 1.3279 | 0.4789 | 1.2606 | 1.3936 | 1.2421 | 0.8658 | 0.8069 | 0.1503 | 0.4397 | 0.7629 | 0.4345 |
| FAD | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Flavin Mononucleotide | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Fructose 1,6-bisphosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Fructose 6-phosphate | 1.5123 | 1.4269 | 0.3899 | 0.6353 | 0.6742 | 0.7422 | 0.9815 | 1.3724 | 0.4221 | 0.5090 | 2.1207 | 0.9490 |
| Fumaric acid | 1.1651 | 1.4376 | 0.8083 | 0.9040 | 1.1396 | 1.0776 | 1.1152 | 1.2493 | 0.4710 | 0.5581 | 1.2271 | 0.9346 |
| Galactonic acid | 1.5135 | 1.8515 | 1.1505 | 1.1936 | 1.5174 | 1.1573 | 0.4476 | 1.0260 | 0.5109 | 0.5359 | 0.6945 | 0.4448 |
| GDP-glucose | NA | NA | 0.6918 | 0.3737 | NA | 1.3104 | 0.7143 | 1.3216 | 1.2043 | 1.0125 | 0.6076 | 1.6178 |
| Gluconic acid | 0.7996 | 1.3879 | 0.8702 | 0.8179 | 1.7028 | 2.1959 | 0.4707 | 1.2542 | 0.2893 | 0.6216 | 0.8532 | 0.6264 |
| Gluconolactone | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Glucosamine | 1.6527 | 1.4144 | 1.3241 | 0.4919 | 0.7830 | 0.3802 | 0.4260 | 1.4963 | 0.5810 | 0.7296 | 1.7248 | 0.7798 |
| Glucosamine 6-phosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Glucose 6-phosphate | 1.0737 | 1.7566 | 0.3194 | 0.8234 | 1.9479 | 1.6049 | 0.4264 | 1.7389 | 0.3838 | 0.5817 | 0.7321 | 0.5421 |
| Glutathione | 0.0340 | 0.0217 | 8.5726 | 0.0196 | 0.0415 | 3.4888 | 0.0666 | 0.0320 | 1.2093 | 0.0557 | 0.0311 | 0.3712 |
| Glycerol 3-phosphate | 0.3443 | 0.3510 | 4.4190 | 0.2404 | 0.4215 | 0.9782 | 0.3389 | 0.8893 | 3.2555 | 0.4886 | 0.4274 | 1.3997 |
| Glycerophosphocholine | 0.3111 | 2.2652 | 1.0419 | 1.4786 | 2.0302 | 2.7026 | 0.1476 | 0.6562 | 0.4066 | 0.1694 | 0.7296 | 0.5663 |
| Glycine | 1.5340 | 1.4575 | 1.6970 | 1.4899 | 1.5750 | 1.8596 | 0.3635 | 0.5272 | 0.3560 | 0.3896 | 0.3619 | 0.3780 |
| Guanidoacetic acid | 1.0277 | 1.2267 | 1.9776 | 1.0765 | 1.1571 | 1.8110 | 0.6344 | 0.8974 | 0.5993 | 0.6084 | 0.7112 | 0.5314 |
| Guanine | 1.1950 | 0.9560 | 2.4675 | 1.0912 | 0.9610 | 1.8981 | 0.4780 | 0.3855 | 1.0657 | 0.5307 | 0.3874 | 0.8235 |
| Guanosine | 1.4498 | 1.4412 | 0.8229 | 1.5376 | 1.6822 | 1.5143 | 0.4596 | 0.5547 | 0.3530 | 0.7690 | 0.4589 | 0.6067 |
| Guanosine diphosphate | 0.7503 | NA | 0.7895 | 0.7779 | 0.9044 | 2.0640 | 0.7238 | 1.0880 | 0.9051 | 0.8970 | 1.0838 | 0.9591 |
| Guanosine monophosphate | 0.5421 | 1.5612 | 1.0850 | 1.2135 | 1.2048 | 1.4088 | 0.9479 | 1.5438 | 0.8053 | 0.7848 | 0.8361 | 0.6767 |
| Guanosine triphosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Hexanoylcarnitine | 0.4252 | 0.6475 | 1.1420 | 1.0013 | 0.5518 | 0.6768 | 1.3393 | 1.8393 | 1.4688 | 1.5266 | 0.8521 | 1.0248 |
| Hippuric acid | 1.0835 | 3.0719 | 0.4380 | 0.9374 | 0.5350 | 0.7396 | 0.7827 | 2.9719 | 0.1348 | 0.8165 | 0.7556 | 0.5453 |
| Homocysteine | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Hydrocinnamic acid | 0.9282 | 1.1172 | 0.8448 | 1.1172 | 1.0019 | 0.9998 | 0.9263 | 1.3151 | 0.6430 | 1.0596 | 1.0168 | 1.0222 |
| Hypotaurine | 0.7994 | 1.2919 | 1.3985 | 0.9816 | 1.8510 | 1.7085 | 0.5167 | 0.8159 | 0.6489 | 0.7294 | 0.6990 | 0.6009 |
| Hypoxanthine | 0.5245 | 1.6814 | 1.4237 | 0.3705 | 1.2690 | 1.8132 | 0.4213 | 1.3945 | 0.8740 | 0.6858 | 0.9126 | 0.9479 |
| IDP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Indole | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Indole-3-carboxylic acid | 1.2495 | 1.3421 | 0.9383 | 1.0251 | 0.8579 | 1.0601 | 1.2610 | 0.6301 | 0.9853 | 0.7600 | 0.9275 | 1.1183 |
| Indolelactic acid | 1.4755 | 2.9754 | 0.9287 | 0.7325 | 1.1750 | 0.9072 | 0.7470 | 1.7835 | 0.2011 | 0.3787 | 0.6135 | 0.5867 |
| Indoxyl sulfate | 1.2246 | 2.7555 | 2.6265 | 0.4350 | 0.8348 | 0.9616 | 0.6269 | 1.2193 | 0.8663 | 0.3250 | 0.6570 | 0.4607 |
| Inosine | 0.9294 | 1.2213 | 0.3717 | 1.1739 | 1.1116 | 1.1816 | 1.1058 | 1.1856 | 0.2599 | 1.2114 | 1.0482 | 0.9255 |
| Inosinic acid | 0.4023 | 0.4014 | 2.1373 | 0.6128 | 0.3676 | 1.0262 | 2.6532 | 1.7183 | 1.0541 | 0.8668 | 0.7730 | 1.0897 |
| Isovalerylcarnitine | 1.1140 | 0.9130 | 1.6649 | 0.9079 | 0.9089 | 1.2019 | 0.7851 | 1.4820 | 0.8208 | 0.8976 | 0.6671 | 0.8243 |
| Kynurenic acid | 0.8813 | 1.0065 | 1.0686 | 0.5301 | 1.0169 | 2.2762 | 0.6825 | 0.9309 | 0.7707 | 0.7543 | 0.8373 | 1.0292 |
| L-Acetylcarnitine | 0.4203 | 0.6025 | 2.7286 | 0.4537 | 0.7626 | 0.9983 | 0.4891 | 1.0368 | 3.1278 | 0.3983 | 0.8170 | 1.3717 |
| L-Alanine | 0.9494 | 1.4693 | 1.0327 | 1.1432 | 1.1443 | 1.3005 | 0.8607 | 1.1001 | 0.5679 | 0.7824 | 0.9459 | 0.8510 |
| L-Arginine | 1.2980 | 1.2742 | 1.2551 | 1.1117 | 1.1351 | 1.1107 | 1.0364 | 0.8349 | 1.0138 | 0.7079 | 0.7242 | 0.6714 |
| L-Asparagine | 1.4067 | 1.4673 | 1.7983 | 1.3089 | 1.0268 | 1.8744 | 0.4435 | 0.5201 | 0.9371 | 0.4339 | 0.3104 | 0.6842 |
| L-Aspartic acid | 1.0767 | 1.1900 | 1.1489 | 0.9182 | 0.9843 | 1.2415 | 0.6705 | 1.5606 | 0.6294 | 0.8675 | 1.0122 | 0.7581 |
| L-Carnitine | 0.6519 | 0.5912 | 1.5218 | 0.7246 | 0.6351 | 1.0077 | 1.1186 | 1.1163 | 1.6552 | 1.1103 | 0.8390 | 1.3501 |
| L-Cystathionine | 1.6446 | 2.1003 | 1.0413 | 1.7836 | 2.7563 | 1.4155 | 0.2314 | 0.3011 | 0.1331 | 0.1519 | 0.2257 | 0.1467 |
| L-Cysteine | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| L-Cystine | 1.6674 | 1.4601 | NA | 0.5937 | 1.5958 | 0.9398 | 0.2326 | 0.2348 | NA | 0.1483 | 0.2807 | 0.7132 |
| L-Dihydroorotic acid | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| L-Glutamic acid | 0.9589 | 1.1663 | 0.8267 | 1.0793 | 1.1404 | 1.1780 | 0.9453 | 1.4658 | 0.9537 | 0.8394 | 0.8872 | 0.7719 |
| L-Glutamine | 0.6808 | 0.7928 | 1.2862 | 0.7995 | 0.6421 | 0.9952 | 0.9525 | 1.3320 | 1.6122 | 0.9801 | 0.9417 | 1.3563 |
| L-Glyceric acid | 0.9627 | 1.3998 | 0.0994 | 1.4759 | 1.1005 | 1.5824 | 0.8228 | 1.5264 | 0.1044 | 0.8300 | 1.1604 | 0.8139 |
| L-Histidine | 1.1349 | 1.1433 | 1.0561 | 1.0156 | 0.9654 | 1.1166 | 1.0718 | 0.9763 | 0.7707 | 0.8918 | 0.9005 | 0.9592 |
| L-Isoleucine | 1.1754 | 1.0508 | 1.1694 | 0.8589 | 0.9906 | 1.8212 | 0.8064 | 0.6893 | 0.4223 | 0.5706 | 0.5132 | 1.6823 |
| L-Kynurenine | 1.2493 | 1.7428 | 1.9972 | 0.9524 | 1.2950 | 0.8286 | 0.7967 | 1.1194 | 0.8711 | 0.4762 | 0.6219 | 0.6342 |
| L-Lactic acid | 0.7090 | 1.1441 | 1.0254 | 1.0731 | 1.0905 | 1.3299 | 0.9621 | 1.2156 | 0.8297 | 0.8195 | 1.1013 | 0.9402 |
| L-Leucine | 1.2524 | 1.0045 | 0.9576 | 0.8686 | 0.8972 | 1.6974 | 0.8931 | 0.6640 | 0.3729 | 0.6148 | 0.4951 | 1.9135 |
| L-Lysine | 0.9941 | 0.9461 | 1.2345 | 1.0378 | 0.9530 | 1.5579 | 0.9011 | 1.0196 | 0.7789 | 0.6934 | 0.7471 | 1.2133 |
| L-Methionine | 1.2873 | 1.3358 | 1.4208 | 0.8666 | 0.8158 | 1.7920 | 0.7449 | 0.9046 | 0.6852 | 0.5554 | 0.3772 | 1.2527 |
| L-Palmitoylcarnitine | 0.5471 | 0.8704 | 0.5038 | 0.9514 | 0.8455 | 0.6146 | 0.1912 | 3.3438 | 0.1909 | 1.3890 | 2.1598 | 0.4310 |
| L-Phenylalanine | 1.1279 | 1.2670 | 1.0888 | 0.9841 | 0.9904 | 1.7728 | 0.8294 | 0.6969 | 0.4581 | 0.5081 | 0.4489 | 1.7237 |
| L-Proline | 1.3681 | 1.3478 | 2.8837 | 0.9575 | 1.0529 | 2.0202 | 0.4570 | 0.3341 | 0.5323 | 0.3242 | 0.2746 | 0.7209 |
| L-Serine | 1.5540 | 1.6950 | 1.0003 | 1.4247 | 1.4896 | 1.4081 | 0.6901 | 0.7169 | 0.2966 | 0.5548 | 0.5567 | 0.5183 |
| L-Threonine | 1.1659 | 1.4165 | 1.3911 | 1.2637 | 1.2626 | 1.6849 | 0.6153 | 0.7752 | 0.6815 | 0.6720 | 0.4819 | 0.6913 |
| L-Tryptophan | 1.1886 | 1.2970 | 1.4069 | 0.8001 | 1.0897 | 1.2537 | 0.8404 | 1.1936 | 0.6172 | 0.6142 | 0.6831 | 1.1330 |
| L-Tyrosine | 1.1356 | 0.7985 | 1.2554 | 0.9447 | 1.1333 | 1.3561 | 0.9222 | 0.7681 | 0.5538 | 0.7595 | 0.5471 | 1.6084 |
| L-Valine | 1.1230 | 1.1215 | 1.6417 | 0.8387 | 1.0938 | 1.8154 | 0.7284 | 0.6754 | 0.6726 | 0.5122 | 0.5028 | 1.2889 |
| Malic acid | 1.2782 | 1.2341 | 0.8498 | 0.9274 | 1.1503 | 1.1147 | 1.3359 | 1.2413 | 0.5004 | 0.5246 | 1.0683 | 0.8704 |
| Methionine sulfoxide | 1.4148 | 0.8728 | 0.3597 | 0.9491 | 0.3656 | 0.8610 | 1.5463 | 1.1257 | 0.5181 | 0.7258 | 0.9142 | 2.0907 |
| Myoinositol | 1.2301 | 1.5329 | 0.8297 | 1.0135 | 1.3472 | 0.7852 | 0.5874 | 1.7573 | 0.5226 | 0.8649 | 1.1514 | 0.4272 |
| N6-Acetyl-L-lysine | 1.0802 | 1.1966 | 1.2140 | 0.9803 | 1.2016 | 2.2155 | 0.6503 | 0.7581 | 0.4518 | 0.4734 | 0.7918 | 0.8856 |
| N6,N6,N6-Trimethyl-L-lysine | 0.9263 | 1.2697 | 1.3578 | 1.1492 | 1.3393 | 1.0445 | 0.7117 | 1.1887 | 0.5887 | 0.6055 | 1.3074 | 0.7559 |
| N-Acetylasparagine | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| N-Acetylaspartylglutamic acid | 0.9722 | 0.9203 | 0.7039 | 0.8987 | 0.3767 | 0.4314 | 1.6899 | 1.9262 | 0.6165 | 1.0683 | 1.4012 | 1.3493 |
| N-Acetyl-D-glucosamine | 1.9740 | 1.4677 | NA | 0.9793 | 1.9786 | 0.9436 | 0.4232 | 0.2960 | NA | 0.4027 | 0.5390 | 0.3887 |
| N-Acetyl-glucosamine 1-phosphate | 1.4830 | 1.9699 | 0.1397 | 1.3490 | 1.4955 | 1.2441 | 0.6023 | 1.4913 | 0.0456 | 0.5606 | 1.0273 | 0.4431 |
| N-Acetylglutamic acid | 1.7153 | 1.4257 | 0.7453 | 1.1009 | 1.0178 | 1.0079 | 0.7600 | 1.5340 | 0.3598 | 0.7261 | 0.8493 | 0.5860 |
| N-Acetylglutamine | 0.5142 | 0.7771 | 0.7273 | 0.8339 | 0.8463 | 1.4310 | 1.0816 | 1.1315 | 0.7556 | 0.9346 | 1.2170 | 1.7026 |
| N-Acetyl-L-alanine | 1.3778 | 1.1460 | 0.9245 | 1.0458 | 1.0599 | 1.2669 | 1.0109 | 1.0421 | 0.3858 | 0.8526 | 0.7935 | 0.8690 |
| N-Acetyl-L-aspartic acid | 0.5906 | 0.9560 | 0.3769 | 1.1945 | 0.7694 | 0.4532 | 1.5301 | 2.0540 | 0.5990 | 1.5477 | 1.3626 | 0.7569 |
| N-Acetyl-L-methionine | 2.3480 | 0.8550 | 1.0663 | 0.6541 | 0.6784 | 1.1115 | 1.5265 | 0.7386 | 0.2687 | 0.6758 | 0.4459 | 0.9930 |
| N-Acetylornithine | 1.0345 | 1.5081 | 1.5749 | 1.1130 | 1.1618 | 1.4644 | 0.5616 | 1.2473 | 0.8028 | 0.5289 | 0.6214 | 0.7960 |
| N-Acetylputrescine | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| N-acetyltryptophan | 0.6685 | 1.5322 | 1.7242 | 0.6900 | 1.2942 | 1.2955 | 0.4665 | 1.6315 | 0.4171 | 0.6926 | 1.1084 | 0.8463 |
| NAD | 0.0873 | 0.1941 | 3.3933 | 0.2956 | 0.1349 | 0.7142 | 0.1809 | 1.6994 | 3.7638 | 1.4319 | 0.3741 | 1.0666 |
| NADH | 0.0742 | 0.1039 | 1.7405 | 0.1303 | 0.0860 | 0.4352 | 0.1202 | 1.9855 | 5.8780 | 0.7057 | 0.3591 | 1.1857 |
| NADP | NA | NA | 1.2388 | 0.3461 | NA | 1.3540 | NA | 1.2183 | 0.9399 | 1.0635 | 0.7646 | 0.7754 |
| NADPH | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| N-Formyl-L-methionine | 0.6751 | 1.0546 | 0.7332 | 0.7867 | 1.0853 | 1.7112 | 1.0323 | 1.3024 | 0.3269 | 1.0550 | 1.1571 | 0.9155 |
| Niacinamide | 0.7722 | 1.1285 | 0.3346 | 1.0588 | 1.0455 | 1.1057 | 0.9971 | 1.6637 | 0.4368 | 0.9699 | 1.4668 | 0.9795 |
| Nicotinamide riboside | 1.2743 | 0.9290 | 0.3210 | 1.1587 | 1.0386 | 0.6825 | 0.7326 | 1.2363 | 0.1652 | 1.9277 | 0.9078 | 0.7399 |
| Nicotinamide ribotide | 0.2340 | 0.3320 | 1.0487 | 0.4621 | NA | 0.7299 | 0.1154 | 2.6012 | 0.8137 | 1.2701 | 0.8577 | 0.7730 |
| Nicotinic acid | 0.8600 | 0.8527 | 0.7039 | 0.8302 | 0.8501 | 1.4223 | 1.5367 | 1.1416 | 0.5929 | 1.1075 | 1.0168 | 0.9820 |
| Nicotinic acid adenine dinucleotide | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Nicotinic acid mononucleotide | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Ornithine | 1.1390 | 1.0212 | 1.0579 | 0.9190 | 0.7879 | 2.0343 | 0.7603 | 0.4672 | 0.6453 | 0.4706 | 0.4652 | 1.9859 |
| Orotic acid | 1.6216 | 2.8144 | 0.6771 | 1.1745 | 1.8107 | 1.4555 | 0.4404 | 0.5699 | 0.1968 | 0.3422 | 0.5598 | 0.3069 |
| Oxalacetic acid | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Oxidized glutathione | 0.4558 | 0.7176 | 4.9632 | 0.3558 | 1.0289 | 1.6224 | 0.1481 | 0.6244 | 2.1527 | 0.4199 | 0.2618 | 0.6114 |
| Oxoglutaric acid | 0.7972 | 0.9008 | 1.6987 | 1.0824 | 0.9411 | 1.2305 | 0.8300 | 0.9374 | 0.8463 | 0.8782 | 0.8102 | 1.2538 |
| Palmitic acid | 1.3182 | 0.7144 | 0.1249 | 0.9188 | 0.8697 | 0.9272 | 1.6225 | 1.4531 | 0.1995 | 1.2035 | 1.2792 | 0.8729 |
| Pantothenic acid | 1.0434 | 1.2329 | 0.5152 | 0.7331 | 1.0835 | 1.1170 | 1.2747 | 1.9986 | 0.8748 | 0.8253 | 0.8412 | 0.7139 |
| Phenylacetylglycine | 0.7799 | 1.2916 | 1.9462 | 0.4876 | 0.8152 | 1.3136 | 0.7828 | 1.4929 | 0.7249 | 0.6003 | 1.5089 | 0.7047 |
| Phenyllactic acid | 0.6805 | 1.9657 | 0.6748 | 1.0405 | 1.1755 | 1.5398 | 0.5686 | 1.4038 | 0.4044 | 0.7825 | 1.0965 | 0.8657 |
| Phosphoenolpyruvic acid | 2.8715 | 0.8565 | 0.3159 | 0.2964 | 0.4884 | 0.3726 | 1.2270 | 2.3238 | 0.1883 | 0.7504 | 1.0626 | 0.4418 |
| Phosphorylcholine | 0.6646 | 1.2759 | 1.4967 | 1.2309 | 0.9332 | 1.4481 | 0.5686 | 1.6843 | 0.8153 | 0.5754 | 1.1539 | 0.7637 |
| Phosphoserine | 1.2220 | 0.8142 | 2.2511 | 0.6530 | 0.5014 | 1.2317 | 0.7363 | 1.1073 | NA | 0.7254 | 0.3497 | 1.4851 |
| Propionylcarnitine | 0.4819 | 0.5698 | 2.6152 | 0.3001 | 0.4751 | 0.7824 | 0.9373 | 0.7170 | 3.3776 | 0.4347 | 0.7653 | 1.7437 |
| Purine | 0.5254 | 0.9417 | 0.2880 | 0.1302 | 0.7116 | 0.9782 | 0.8155 | 3.4208 | 0.4811 | 1.7908 | 1.2744 | 0.5625 |
| Pyridoxine | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Pyroglutamic acid | 0.8820 | 1.0920 | 0.6777 | 0.9005 | 1.0919 | 1.0750 | 1.0395 | 1.3493 | 1.0224 | 1.0735 | 0.9918 | 0.8463 |
| Pyruvic acid | 0.9165 | 1.2037 | 1.2895 | 1.0445 | 1.1255 | 1.1968 | 0.8983 | 0.9756 | 0.7923 | 0.8678 | 0.8729 | 0.9564 |
| Riboflavin | 2.7983 | 1.1619 | 0.1112 | 0.6493 | 1.7287 | 0.9484 | 0.3697 | 0.4226 | NA | 0.5957 | 0.5266 | 0.4610 |
| S-Adenosylhomocysteine | 1.3236 | 0.9911 | 1.4758 | 0.8416 | 1.2227 | 1.0470 | 0.8386 | 1.4293 | 0.3979 | 0.9739 | 0.9185 | 0.4322 |
| S-Adenosylmethionine | 1.4492 | 1.4605 | 0.6155 | 1.2998 | 1.1533 | 1.2440 | 1.1072 | 0.8548 | 0.4236 | 0.6841 | 0.8736 | 0.7105 |
| Sedoheptulose 1,7-bisphosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Succinic acid | 0.3550 | 0.8306 | 1.1218 | 0.7850 | 1.0357 | 1.0427 | 0.4127 | 1.6537 | 1.2779 | 1.4346 | 1.1939 | 0.9537 |
| Succinyl-CoA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Taurine | 0.6911 | 1.0029 | 1.0497 | 0.9027 | 0.8858 | 0.9473 | 1.0116 | 1.5024 | 1.1226 | 1.0422 | 1.0761 | 1.0518 |
| Taurochenodesoxycholic acid | 0.3977 | 0.4690 | 0.3490 | 0.1462 | 3.4339 | 1.1365 | 0.5121 | 2.9887 | 0.3898 | 0.8423 | 0.4818 | 0.5902 |
| Thiamine | 1.9238 | 1.1464 | 0.0886 | 1.0218 | 1.2426 | 1.1432 | 1.6209 | 0.6363 | 0.0494 | 0.8339 | 0.6308 | 0.9309 |
| Thiamine monophosphate | 0.7366 | 0.9521 | 0.7953 | 0.5016 | 0.9791 | 0.6565 | 1.0977 | 2.3608 | 0.9624 | 0.8755 | 1.0524 | 1.2001 |
| Threonic acid | 1.2686 | 1.3059 | 0.5215 | 1.4771 | 1.3108 | 1.3570 | 0.8592 | 1.2799 | 0.1227 | 0.7555 | 1.0238 | 0.5652 |
| Thymidine | 1.0270 | 0.7341 | 0.7299 | 0.6182 | 0.7135 | 1.0069 | 1.0863 | 1.3782 | 0.7347 | 0.8341 | 1.0647 | 1.8792 |
| Thymidine 5^-triphosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Thymine | 0.5837 | 0.4663 | 0.9030 | 0.4460 | 0.4559 | 1.8602 | 1.2390 | 0.5606 | 0.6805 | 0.6690 | 0.4517 | 3.3651 |
| Uracil | 1.0215 | 1.1698 | 1.1395 | 1.1224 | 1.2074 | 1.6391 | 0.9023 | 0.9308 | 0.3635 | 0.6404 | 0.6023 | 1.2500 |
| Ureidosuccinic acid | 1.3015 | 2.7367 | 2.1338 | 0.7789 | 1.1852 | 1.2382 | 0.2900 | 0.5594 | 0.5087 | 0.4153 | 0.7388 | 0.5436 |
| Uric acid | 1.3868 | 1.4180 | 0.1843 | 1.6074 | 1.3085 | 0.8435 | 1.0459 | 1.2328 | 0.0284 | 0.8546 | 1.1791 | 0.6692 |
| Uridine | 1.0443 | 1.5920 | 0.5721 | 1.2926 | 1.3102 | 1.3047 | 0.6024 | 1.1667 | 0.5018 | 0.7421 | 1.0817 | 0.7699 |
| Uridine 5^-diphosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Uridine 5^-monophosphate | 0.5713 | 0.7732 | 2.6751 | 0.5947 | 0.5456 | 1.1649 | 1.0678 | 1.9945 | 1.6952 | 0.6023 | 0.8805 | 0.6438 |
| Uridine diphosphate glucose | 0.3337 | 0.5858 | 2.8228 | 0.6826 | 0.5791 | 1.2828 | 0.8106 | 1.2562 | 1.7946 | 0.8939 | 0.8795 | 0.7646 |
| Uridine diphosphate glucuronic acid | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Uridine diphosphate-N-acetylglucosamine | 0.3764 | 0.6344 | 3.0821 | 1.0560 | 0.5413 | 1.2421 | 1.0717 | 1.6464 | 1.4456 | 0.7397 | 0.8947 | 0.5430 |
| Uridine triphosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Urocanic acid | 0.4560 | 0.4975 | 1.1876 | 0.2579 | 0.5288 | 2.1774 | 1.0118 | 0.3828 | 1.0049 | 0.5799 | 0.4764 | 3.2080 |
| Xanthine | 1.1804 | 1.2716 | 0.7627 | 0.6677 | 1.2697 | 1.3024 | 0.8348 | 1.1658 | 0.6010 | 0.6440 | 0.9877 | 1.1386 |
| Xanthurenic acid | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Factors:
| F1 | Genotype:CHCHD10 S55L+/- | Sex:F | Age (d):125 |
| F2 | Genotype:CHCHD10 S55L+/- | Sex:F | Age (d):225 |
| F3 | Genotype:CHCHD10 S55L+/- | Sex:F | Age (d):75 |
| F4 | Genotype:CHCHD10 S55L+/- | Sex:M | Age (d):125 |
| F5 | Genotype:CHCHD10 S55L+/- | Sex:M | Age (d):225 |
| F6 | Genotype:CHCHD10 S55L+/- | Sex:M | Age (d):75 |
| F7 | Genotype:WT | Sex:F | Age (d):125 |
| F8 | Genotype:WT | Sex:F | Age (d):225 |
| F9 | Genotype:WT | Sex:F | Age (d):75 |
| F10 | Genotype:WT | Sex:M | Age (d):125 |
| F11 | Genotype:WT | Sex:M | Age (d):225 |
| F12 | Genotype:WT | Sex:M | Age (d):75 |
