Data for (Study ST002157)
(Analysis AN003532)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 | F21 | F22 | F23 | F24 | F25 | F26 | F27 | F28 | F29 | F30 | F31 | F32 | F33 | F34 | F35 | F36 | F37 | F38 | F39 | F40 | F41 | F42 | F43 | F44 | F45 | F46 | F47 | F48 | F49 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2-Phosphoglyceric acid | 0.2802 | NA | 0.5177 | 0.2426 | 0.3124 | 2.2430 | 4.4776 | NA | 0.2507 | 0.3566 | 0.9788 | 0.0100 | 0.1878 | NA | 0.7241 | 2.6738 | 2.8122 | 1.4418 | 0.4371 | NA | 0.9842 | 3.4647 | 0.2115 | 0.4060 | NA | 0.9718 | NA | 0.3895 | 0.3855 | 0.6591 | 0.1825 | 0.4780 | NA | 0.5477 | 0.0166 | 0.2086 | 0.0977 | 1.5707 | NA | 1.1875 | 1.6507 | 1.2410 | 2.7383 | 0.8007 | NA | 0.6925 | 0.7006 | 1.7879 | 0.6806 |
| 3-Hydroxyglutaric acid | 1.8364 | NA | 1.2834 | 0.7330 | 0.9462 | 0.7034 | 2.3257 | NA | 1.4264 | 0.5643 | 0.8381 | 0.1785 | 0.8927 | NA | 1.0088 | 0.6680 | 0.7577 | 0.3678 | 1.5058 | NA | 1.4008 | 1.0474 | 1.0864 | 0.4749 | NA | 0.9922 | NA | 1.1013 | 0.7282 | 1.0507 | 1.0798 | 1.3827 | NA | 0.7479 | 1.2822 | 1.4461 | 0.1393 | 1.3275 | NA | 0.8134 | 0.1097 | 0.7854 | 0.9711 | 1.8227 | NA | 0.9711 | 0.1270 | 1.4510 | 1.6249 |
| 5-Methyltetrahydrofolic acid | 0.4742 | NA | 0.7264 | 0.7910 | 0.6873 | 0.8602 | 0.4141 | NA | 0.2711 | 0.4679 | 0.3424 | NA | 0.3386 | NA | 0.3048 | 1.9117 | 2.0120 | 1.7655 | 0.8485 | NA | 1.3375 | 1.6964 | 4.6107 | 0.0407 | NA | 0.7215 | NA | 0.6721 | 2.1248 | 0.5322 | 0.6239 | 0.4518 | NA | 0.6629 | 1.0739 | 0.4351 | 0.4049 | 1.1862 | NA | 0.6736 | 2.5271 | 0.4117 | 1.0884 | 0.7968 | NA | 0.7742 | 2.3813 | 0.7618 | 0.7948 |
| Acetylglycine | 0.6831 | NA | 0.7569 | 0.7822 | 0.6860 | 1.0563 | 1.3761 | NA | 0.6587 | 0.9007 | 1.1986 | 0.3527 | 0.9044 | NA | 1.1663 | 1.7117 | 2.2311 | 0.1008 | 1.1399 | NA | 1.1605 | 1.9429 | 1.9538 | 0.0873 | NA | 0.9003 | NA | 0.6192 | 1.4175 | 0.8818 | 0.8358 | 1.0134 | NA | 0.9694 | 0.0111 | 0.9812 | 0.0959 | 1.0004 | NA | 0.9863 | 1.8215 | 1.1709 | 1.4369 | 1.2968 | NA | 0.9678 | 0.0263 | 1.2503 | 1.4672 |
| Adenosine monophosphate | 1.2470 | NA | 0.5198 | 0.6305 | 1.3094 | 2.2144 | 1.4621 | NA | 1.1763 | 0.7254 | 1.4895 | 0.0340 | 0.1920 | NA | 0.0348 | 1.9483 | 1.0737 | 1.8552 | 0.5892 | NA | 1.2960 | 3.8903 | 2.3309 | 1.1368 | NA | 0.9402 | NA | 0.4225 | 0.4629 | 0.2668 | 0.3537 | 1.0185 | NA | 0.1546 | 0.7341 | 0.2285 | 0.4950 | 2.7201 | NA | 0.1874 | 2.9296 | 0.1442 | 0.7794 | 1.1610 | NA | 0.4584 | 1.0527 | 0.0684 | 0.2665 |
| Adenosine triphosphate | 1.2218 | NA | 0.0484 | 0.8048 | 1.2279 | 1.3563 | 1.0482 | NA | 0.9524 | 1.1272 | 1.2041 | 0.3992 | 1.5201 | NA | 1.3531 | 1.9705 | 2.1083 | 1.4916 | 1.1841 | NA | 0.9271 | 1.7311 | 1.8368 | 0.9405 | NA | 0.7330 | NA | 0.4519 | 0.2829 | 1.2570 | 0.6402 | 0.6896 | NA | 0.2984 | 0.3730 | 1.1690 | 0.8228 | 0.5720 | NA | 0.6657 | 0.4126 | 1.7419 | 1.0058 | 0.9707 | NA | 0.5552 | 0.4212 | 1.8325 | 0.6512 |
| ADP | 1.1945 | NA | 0.6139 | 0.8447 | 1.3895 | 2.5629 | 1.1936 | NA | 1.2125 | 1.0431 | 1.3326 | 0.3717 | 0.0641 | NA | 0.8310 | 2.3964 | 1.5253 | 1.9394 | 1.0185 | NA | 1.2395 | 2.9789 | 0.2412 | 1.0789 | NA | 0.9004 | NA | 0.4618 | 0.5032 | 0.6284 | 0.5652 | 0.8688 | NA | 0.2604 | 0.6947 | 0.4103 | 0.7123 | 1.3026 | NA | 0.4309 | 1.6090 | 0.5163 | 1.1063 | 1.1689 | NA | 0.6936 | 0.7608 | 1.2948 | 0.0393 |
| ADP-glucose | 1.3917 | NA | 0.7240 | 0.6739 | 0.2135 | 1.4625 | 0.9901 | NA | 0.7443 | 0.7415 | 1.0544 | 0.2836 | 0.9945 | NA | 1.2552 | 2.2769 | 1.3816 | 0.8743 | 0.9927 | NA | 0.7652 | 1.7432 | 1.0854 | 0.7105 | NA | 0.6157 | NA | 1.0178 | 1.4977 | 0.8714 | 0.7241 | 0.9377 | NA | 0.6577 | 0.7338 | 1.7261 | 0.8070 | 0.8723 | NA | 1.0640 | 1.4053 | 0.9841 | 0.9142 | 1.0267 | NA | 0.1199 | 1.0534 | 0.9795 | 1.6328 |
| Alpha-D-Glucose | 0.9709 | NA | 1.2075 | 0.9257 | 0.9489 | 1.7751 | 1.4292 | NA | 1.0605 | 0.8566 | 0.7615 | 0.6943 | 0.1087 | NA | 1.1785 | 0.9643 | 0.8659 | 0.7830 | 1.5508 | NA | 1.4205 | 0.1266 | 0.1129 | 0.0548 | NA | 1.0771 | NA | 0.9933 | 1.1480 | 1.2297 | 1.2072 | 1.0765 | NA | 1.1465 | 1.2710 | 0.9497 | 1.0184 | 1.0991 | NA | 1.0695 | 1.2342 | 1.1768 | 1.1451 | 1.0796 | NA | 1.1555 | 1.7671 | 0.1375 | 1.2222 |
| cis-Aconitic acid | 0.6577 | NA | 0.6682 | 0.7706 | 1.0149 | 1.1878 | 0.1305 | NA | 0.6636 | 0.9881 | 1.1597 | 0.1504 | 0.9163 | NA | 1.8862 | 2.4854 | 1.9182 | 1.2642 | 1.2504 | NA | 1.7040 | 0.1489 | 1.6685 | 0.7493 | NA | 0.4728 | NA | 0.5846 | 0.5368 | 1.0688 | 0.6523 | 0.9970 | NA | 1.1956 | 0.6259 | 0.7608 | 0.8230 | 0.9301 | NA | 0.7738 | 0.9031 | 1.0633 | 1.1824 | 1.5768 | NA | 0.8316 | 1.0198 | 1.7638 | 0.8547 |
| Coenzyme A | 0.2540 | NA | 0.5707 | 0.5978 | 0.9722 | 2.3584 | 1.0121 | NA | 0.4409 | 0.7101 | 1.3237 | 0.4115 | 0.5792 | NA | 1.0361 | 3.1036 | 1.6884 | 1.2283 | 0.6654 | NA | 0.9179 | 2.5876 | 2.0587 | 0.8888 | NA | 0.8114 | NA | 0.6470 | 0.8390 | 0.7144 | 0.6251 | 0.8239 | NA | 0.6871 | 0.7173 | 0.0375 | 0.5777 | 0.6144 | NA | 1.0918 | 1.9981 | 0.6830 | 0.9028 | 0.9172 | NA | 1.1981 | 1.0613 | 0.9128 | 0.7348 |
| Cytidine | 1.1407 | NA | 0.1776 | 2.2688 | 2.2999 | 1.3496 | 1.2424 | NA | 1.3832 | 1.9991 | 0.1690 | 0.0719 | 0.0552 | NA | 0.7822 | 0.1479 | 1.4724 | 1.7879 | 0.1244 | NA | 1.0870 | 1.5798 | 2.1724 | 1.1833 | NA | 1.4235 | NA | 0.9837 | 1.2074 | 1.2702 | 0.1218 | 1.3007 | NA | 0.9105 | 1.0663 | 1.0082 | 1.1594 | 0.8622 | NA | 0.5236 | 0.7155 | 0.7935 | 0.3842 | 1.1449 | NA | 0.6488 | 1.1672 | 0.0080 | 0.8055 |
| Cytidine monophosphate | 2.8246 | NA | 1.0285 | 0.7954 | 1.5422 | 2.8956 | 2.1650 | NA | 1.6228 | 0.6986 | 1.7611 | 0.0062 | 0.2673 | NA | 0.5842 | 2.2930 | 1.3487 | 1.4305 | 0.6713 | NA | 0.9889 | 0.2168 | 2.3303 | 0.1529 | NA | 0.0922 | NA | 0.4584 | 0.8440 | 0.5044 | 0.5433 | 0.9577 | NA | 0.1821 | 0.7898 | 0.2182 | 0.8630 | 1.5188 | NA | 0.2570 | 2.4646 | 0.1583 | 0.7870 | 1.0346 | NA | 0.5199 | 1.0131 | 0.7652 | 0.4043 |
| Cytidine triphosphate | 0.8877 | NA | 0.9649 | 1.0199 | 0.1365 | 1.4461 | 1.1463 | NA | 1.2175 | 1.1328 | 1.2210 | 0.6645 | 1.6259 | NA | 1.2162 | 1.7611 | 3.2335 | 1.2296 | 0.9023 | NA | 0.6491 | 1.2186 | 1.5457 | 1.3750 | NA | 0.9092 | NA | 0.4882 | 0.0278 | 1.7441 | 0.8939 | 0.7580 | NA | 0.5998 | 0.3711 | 1.4650 | 0.6997 | 0.5190 | NA | 0.7278 | 0.3614 | 1.9243 | 0.0858 | 0.7974 | NA | 0.4559 | 0.5630 | 1.4210 | 0.5936 |
| Deoxyguanosine | 0.4282 | NA | 0.1983 | 0.4901 | 1.5417 | 0.6238 | 0.5116 | NA | 0.5110 | 3.9326 | 2.2965 | 0.1418 | 1.2477 | NA | 3.4690 | 0.6211 | 0.4840 | 0.4311 | 0.7374 | NA | 1.5799 | NA | 1.0629 | 0.3159 | NA | 2.4929 | NA | 0.0566 | 0.3529 | 0.8391 | 1.7806 | 0.9201 | NA | 3.2038 | 0.7409 | 1.4874 | 0.5860 | 0.0162 | NA | 0.0199 | 0.0372 | 2.4240 | NA | 0.5497 | NA | 0.5237 | 0.9102 | 0.2205 | 0.2135 |
| dGTP | 0.1288 | NA | 0.5149 | 0.8561 | 1.3156 | 0.0145 | 1.1074 | NA | 0.9944 | 1.1825 | 1.2952 | 0.4390 | 1.6541 | NA | 1.4659 | 2.1806 | 2.2901 | 1.5990 | 1.2941 | NA | 0.9948 | 1.9167 | 1.9315 | 1.0001 | NA | 0.7832 | NA | 0.5053 | 0.0303 | 1.3467 | 0.6942 | 0.7406 | NA | 0.3112 | 0.4064 | 1.3044 | 0.8723 | 0.6103 | NA | 0.0714 | 0.4519 | 1.8907 | 1.0632 | 1.0234 | NA | 0.5944 | 0.4422 | 1.9798 | 0.7029 |
| D-Lactic acid | 0.9689 | NA | 1.0988 | 0.8400 | 0.8952 | 1.1474 | 1.1198 | NA | 0.0883 | 0.7932 | 0.7561 | 0.6851 | 1.0283 | NA | 1.0197 | 0.1482 | 1.2214 | 1.1621 | 1.2905 | NA | 1.0676 | 0.8797 | 1.1619 | 1.0922 | NA | 1.2271 | NA | 0.9984 | 1.4580 | 0.9926 | 0.9701 | 1.0434 | NA | 1.1782 | 1.1606 | 1.1281 | 0.9098 | 1.1598 | NA | 1.2341 | 1.4816 | 1.0634 | 0.7754 | 0.1464 | NA | 1.1378 | 1.5186 | 0.8729 | 1.0792 |
| D-Ribose 5-phosphate | 1.3965 | NA | 0.4115 | 0.2503 | 0.8315 | 1.8596 | 1.2960 | NA | 0.8684 | 0.3313 | 1.3425 | 0.9854 | 0.7547 | NA | 0.8786 | 0.2088 | 1.2333 | 0.8657 | 0.8381 | NA | 0.9700 | 1.2948 | 1.2727 | 1.3198 | NA | 1.2007 | NA | 1.1092 | 0.7318 | 0.5206 | 0.4963 | 1.1033 | NA | 0.4253 | 1.2703 | 0.4874 | 0.6230 | 1.9690 | NA | 1.3122 | 3.2225 | 0.6863 | 0.1240 | 1.1572 | NA | 1.3513 | 1.1917 | 1.1567 | 0.6517 |
| FAD | 1.1895 | NA | 1.3999 | 1.5645 | 1.5760 | 1.5390 | 1.3355 | NA | 0.1176 | 1.3065 | 1.0656 | 0.0576 | 0.0902 | NA | 1.0959 | 1.2921 | 1.4946 | 1.0438 | 1.4496 | NA | 1.1974 | 0.6879 | 1.4553 | 0.7652 | NA | 0.9469 | NA | 0.8652 | 1.2974 | 1.0779 | 1.2093 | 1.3595 | NA | 0.8029 | 1.1842 | 0.6643 | 1.1544 | 0.7221 | NA | 0.0588 | 0.9163 | 0.1035 | 0.6649 | 1.1168 | NA | 0.6326 | 1.8054 | 0.7154 | 0.9785 |
| Folic acid | 0.8178 | NA | 0.9164 | 0.5520 | 0.4150 | 0.8067 | 1.5888 | NA | 0.7118 | 0.6681 | 0.5771 | 0.0470 | 0.1262 | NA | 1.5003 | 1.0903 | 1.2717 | 0.6878 | 1.8617 | NA | 1.4818 | 0.9629 | 0.9992 | 0.4727 | NA | 0.7407 | NA | 0.9568 | NA | 0.9312 | 0.7364 | 0.6719 | NA | 3.0708 | NA | 0.6199 | 0.8760 | 0.6436 | NA | 2.2567 | 0.0003 | 1.4086 | 1.5507 | 1.2038 | NA | 1.9223 | 1.1864 | 0.0113 | 1.6576 |
| Fructose 1,6-bisphosphate | 0.9134 | NA | 0.2190 | 1.5241 | 0.8159 | 0.1565 | 0.2585 | NA | 3.9445 | 2.4656 | 0.4463 | 0.1602 | 0.8783 | NA | 0.4275 | 1.6351 | 0.1004 | 0.0224 | 0.5357 | NA | 0.5022 | 0.1491 | 3.8932 | 0.3597 | NA | 0.0130 | NA | NA | NA | 0.4921 | 0.1763 | 0.6957 | NA | 0.9447 | 1.6955 | NA | 2.7596 | 4.3744 | NA | 0.4020 | 1.4968 | 0.1416 | 0.1464 | 1.3117 | NA | 0.0485 | 0.0601 | 2.4794 | 0.3549 |
| Fumaric acid | 0.0311 | NA | 0.4310 | 0.7935 | 0.6760 | 2.1138 | 0.8366 | NA | 0.3468 | 0.8815 | 1.1666 | 0.5937 | 1.1887 | NA | 1.5674 | 2.6081 | 2.9083 | 1.7607 | 0.6412 | NA | 0.9487 | 1.4209 | 1.8210 | 1.6892 | NA | 0.7339 | NA | 0.5870 | 0.2631 | 0.8470 | 0.0401 | 0.9090 | NA | 0.9376 | 0.7923 | 0.6195 | 0.3997 | 1.0129 | NA | 0.9423 | 0.9659 | 1.3351 | 0.3500 | 0.8717 | NA | 1.0998 | 0.9944 | 1.2613 | 0.6127 |
| Glucose 6-phosphate | 1.4749 | NA | 0.3722 | 0.6148 | 1.2108 | 1.5636 | 1.3468 | NA | 1.1050 | 0.5849 | 1.1514 | NA | 0.8911 | NA | 1.1298 | 0.1809 | 0.9104 | 1.1673 | 1.2515 | NA | 1.1136 | 1.0389 | 1.0269 | 1.1461 | NA | 0.5121 | NA | 0.3843 | 0.7892 | 1.2218 | 0.5730 | 0.9670 | NA | 0.0444 | 0.8133 | 0.6434 | 0.9687 | 1.9301 | NA | 0.7416 | 2.9369 | 0.8390 | 1.0605 | 1.5496 | NA | 0.4873 | 0.9422 | 1.7291 | 0.5855 |
| Glutathione | 0.1767 | NA | 0.4974 | 0.7719 | 0.9143 | 2.1544 | 0.5644 | NA | 0.2630 | 1.0158 | 1.5220 | 0.8754 | 1.2940 | NA | 1.2747 | 2.3110 | 1.9784 | 1.6950 | 0.0910 | NA | 0.1047 | 1.4926 | 1.7369 | 1.4957 | NA | 0.8591 | NA | 0.6252 | 1.4021 | 0.0816 | 0.6834 | 0.8829 | NA | 0.6666 | 0.9710 | 0.7677 | 0.5344 | 0.9753 | NA | 1.0584 | 1.7493 | 1.2371 | 0.1069 | 1.1593 | NA | 1.2128 | 1.5149 | 1.2046 | 0.0783 |
| Guanosine | 0.4502 | NA | 1.6246 | 1.3259 | 1.1570 | 0.7094 | 0.8085 | NA | 0.5776 | 1.1394 | 0.7829 | 0.1678 | 1.0940 | NA | 1.2846 | 0.8889 | 1.7059 | 0.5520 | 1.5309 | NA | 1.5746 | 0.8178 | 1.3978 | 0.2472 | NA | 1.0475 | NA | 0.5329 | 0.1273 | 1.4804 | 1.4971 | 1.6918 | NA | 1.0076 | 1.3233 | 0.6809 | 1.0382 | 0.0986 | NA | 0.0486 | 0.8036 | 1.4314 | 0.9269 | 1.3748 | NA | 0.0529 | 3.1605 | 0.8121 | 1.0264 |
| Guanosine diphosphate | 0.9699 | NA | 0.7320 | 0.0874 | 1.4093 | 0.0211 | 1.2947 | NA | 1.1498 | 1.0474 | 0.0013 | 0.4093 | 0.7383 | NA | 1.0691 | 2.2937 | 1.8818 | 1.9060 | 0.0119 | NA | 1.4400 | 3.0169 | 2.4932 | 0.9617 | NA | 0.1075 | NA | 0.6876 | 0.7631 | 0.7179 | 0.8477 | 1.1446 | NA | 0.4868 | 0.9778 | 0.4993 | 0.9147 | 1.0907 | NA | 0.0595 | 1.4817 | 0.6116 | 1.1436 | 1.4317 | NA | 0.8143 | 1.3270 | 1.1741 | 0.7837 |
| Guanosine triphosphate | 0.7760 | NA | 0.0514 | 0.7640 | 1.1261 | 0.9820 | 0.1026 | NA | 0.8617 | 1.1155 | 1.0156 | 0.3931 | 1.8303 | NA | 1.6616 | 2.1987 | 2.6728 | 1.2882 | 1.3041 | NA | 0.9536 | 1.6630 | 1.8550 | 0.7309 | NA | 0.0078 | NA | 0.5880 | 0.3635 | 1.3268 | 0.8965 | 0.7562 | NA | 0.4934 | 0.5063 | 1.2263 | 0.9324 | 0.4521 | NA | 0.9165 | 0.3325 | 1.8835 | 0.9820 | 0.9090 | NA | 0.6211 | 0.5833 | 1.8129 | 1.0639 |
| Hydroxyphenyllactic acid | 1.0240 | NA | 1.2142 | 0.0697 | 1.0352 | 1.0297 | 1.8209 | NA | 1.4052 | 0.0465 | 0.5965 | 0.3528 | 0.0831 | NA | 0.6713 | 1.3108 | 1.7361 | 0.6160 | 1.6221 | NA | 0.9958 | 1.2658 | 0.2242 | 0.0818 | NA | 1.2806 | NA | 0.0940 | 0.8608 | 1.2263 | 1.3398 | 1.1695 | NA | 0.9971 | 1.4063 | 0.9672 | 1.2444 | 1.3818 | NA | 1.0323 | 1.9607 | 0.1356 | 1.3474 | 0.1727 | NA | 0.9965 | 2.3984 | 1.3636 | 1.4231 |
| Inosine | 0.6790 | NA | 0.1203 | 1.1790 | 1.2979 | 0.9367 | 1.0176 | NA | 0.6988 | 1.1447 | 0.8913 | 0.2989 | 1.5480 | NA | 1.4628 | 0.1070 | 1.7447 | 0.8667 | 1.5532 | NA | 1.6268 | 1.0898 | 1.4597 | 0.3557 | NA | 1.1807 | NA | 0.7438 | 1.0644 | 1.4836 | 0.1599 | 1.2620 | NA | 0.9790 | 1.3626 | 0.9004 | 1.0014 | 0.1967 | NA | 0.7663 | 0.8782 | 1.6719 | 0.1238 | 1.1480 | NA | 0.7766 | 1.8631 | 1.3262 | 1.0327 |
| L-Asparagine | 1.0386 | NA | 0.9079 | 0.7034 | 0.7770 | 2.2567 | 1.1693 | NA | 0.7367 | 0.7884 | 0.9089 | 0.0581 | 0.1010 | NA | 0.1008 | 1.4389 | 1.5543 | 1.1952 | 0.6463 | NA | 0.1270 | 1.5050 | 1.0899 | 0.0821 | NA | 1.3165 | NA | 0.7200 | 1.4620 | 0.7195 | 0.9310 | 1.0333 | NA | 0.0896 | 1.0423 | 0.9979 | 1.0209 | 0.8247 | NA | 0.9410 | 2.3477 | 1.1882 | 1.4119 | 1.6965 | NA | 0.9879 | 2.9476 | 1.0174 | 0.1189 |
| L-Aspartic acid | 0.2808 | NA | 0.4936 | 0.1557 | 1.4868 | 2.2965 | 1.3542 | NA | 0.3537 | 3.1935 | 3.1682 | 0.8090 | 1.0665 | NA | 1.1974 | 0.3625 | 2.4956 | 0.3905 | 0.6927 | NA | 0.9276 | 3.4930 | 0.0318 | 1.6770 | NA | 0.5417 | NA | 0.2518 | 0.1033 | 0.6691 | 0.6085 | 0.9956 | NA | 0.9371 | 0.7112 | 0.8467 | 0.5513 | 0.7420 | NA | 0.5403 | 1.0154 | 0.9799 | 0.0586 | 0.7500 | NA | 0.7644 | 0.9567 | 1.1829 | 0.8670 |
| L-Glutamine | 1.0566 | NA | 0.0905 | 1.0339 | 0.9853 | 0.1853 | 0.1203 | NA | 0.0846 | 1.2381 | 1.8428 | 1.4419 | 1.0508 | NA | 0.9584 | 1.2923 | 1.2568 | 1.8798 | 1.2181 | NA | 0.9685 | 0.1127 | 1.6717 | 2.1733 | NA | 1.2962 | NA | 0.9601 | 0.5257 | 1.3675 | 0.8053 | 1.0082 | NA | 1.5872 | 0.3744 | 0.9464 | 1.1445 | 0.7042 | NA | 1.3916 | 0.4508 | 0.7106 | 0.3921 | 1.5879 | NA | 1.4833 | 0.6756 | 0.8795 | 1.0469 |
| L-Leucine | 0.7167 | NA | 0.8362 | 0.0808 | 0.7997 | 1.0995 | 1.4771 | NA | 0.0645 | 0.9303 | 1.1361 | 0.3948 | 1.0414 | NA | 1.1443 | 1.4935 | 1.4551 | 1.0500 | 1.1198 | NA | 1.0659 | 1.5450 | 1.4788 | 0.7457 | NA | 0.0839 | NA | 0.6278 | 1.4780 | 0.9668 | 0.7859 | 0.8693 | NA | 1.0683 | 1.1806 | 0.9153 | 0.8764 | 0.8929 | NA | 0.0088 | 1.8806 | 1.0505 | 1.2815 | 1.0151 | NA | 0.9496 | 2.0397 | 1.1083 | 1.2452 |
| L-Lysine | 0.5261 | NA | 1.3183 | 0.9734 | 0.9896 | 1.4868 | 1.5767 | NA | 1.0464 | 0.9737 | 0.8250 | 0.6957 | 1.1024 | NA | 0.8928 | 1.1690 | 1.3507 | 1.1336 | 1.0636 | NA | 1.0777 | 1.4000 | 2.0502 | 0.5694 | NA | 0.9918 | NA | 0.6841 | 0.7829 | 0.1018 | 1.0852 | 1.0035 | NA | 1.3196 | 1.2472 | 0.5056 | 0.7798 | 0.8436 | NA | 0.8971 | 1.3197 | 0.0121 | 0.9492 | 0.7128 | NA | 0.7759 | 2.1776 | 0.7595 | 0.8302 |
| L-Methionine | 0.6646 | NA | 1.0411 | 0.8527 | 0.9032 | 2.6278 | 1.0809 | NA | 0.5573 | 0.9437 | 1.0656 | 0.4352 | 0.9807 | NA | 0.9912 | 0.0153 | 1.2472 | 1.0952 | 1.1528 | NA | 0.9524 | 2.2050 | 1.6019 | 0.6753 | NA | 0.8393 | NA | 0.7199 | 0.0965 | 0.9644 | 0.8583 | 0.0095 | NA | 1.0457 | 0.8292 | 0.7464 | 0.8522 | 0.9934 | NA | 1.0490 | 1.6500 | 1.1344 | 1.3724 | 1.2178 | NA | 0.9360 | 1.2180 | 1.0349 | 1.3438 |
| L-Phenylalanine | 0.8316 | NA | 0.7663 | 0.7596 | 0.9081 | 1.2412 | 1.5343 | NA | 0.7005 | 0.8541 | 1.2410 | 0.4602 | 1.1533 | NA | 1.1732 | 1.7922 | 1.6643 | 1.1906 | 0.1227 | NA | 1.0526 | 1.7992 | 0.1551 | 0.8785 | NA | 0.9438 | NA | 0.6293 | 1.2370 | 1.0436 | 0.8951 | 0.0927 | NA | 0.9205 | 1.0027 | 0.0947 | 0.8780 | 1.0945 | NA | 1.0397 | 1.8310 | 1.2225 | 1.4486 | 0.1226 | NA | 0.8115 | 1.6699 | 1.2951 | 1.4484 |
| L-Ribulose | 1.1838 | NA | 0.3502 | 0.2283 | 0.7510 | 2.2866 | 1.3155 | NA | 0.9147 | 0.4161 | 1.3918 | 0.9020 | 0.6717 | NA | 0.0084 | 2.1928 | 0.1301 | 0.9735 | 0.7674 | NA | 0.9612 | 1.9211 | 1.5880 | 1.5493 | NA | 1.2040 | NA | 0.9302 | 0.7420 | 0.4651 | 0.4364 | 1.0722 | NA | 0.4573 | 1.2768 | 0.5035 | 0.6274 | 1.9171 | NA | 1.1461 | 3.1039 | 0.5919 | 0.1427 | 1.2858 | NA | 1.3419 | 1.1354 | 1.1108 | 0.0062 |
| L-Tryptophan | 0.0721 | NA | 0.7615 | 0.0798 | 0.6840 | 0.0986 | 1.2028 | NA | 0.6394 | 0.9268 | 1.1140 | 0.3502 | 0.9539 | NA | 1.0197 | 1.5861 | 1.6289 | 0.9464 | 1.0634 | NA | 1.0134 | 1.8833 | 1.5979 | 0.7710 | NA | 0.8179 | NA | 0.6593 | 1.3025 | 0.7825 | 0.7955 | 0.9316 | NA | 1.0114 | 0.9977 | 0.9094 | 0.8880 | 0.9419 | NA | 0.9598 | 1.6238 | 0.9810 | 1.3186 | 1.1807 | NA | 0.9482 | 2.0666 | 1.0767 | 1.4138 |
| L-Tyrosine | 0.6965 | NA | 0.8985 | 0.9102 | 0.0910 | 1.2858 | 1.1507 | NA | 0.7630 | 1.0431 | 0.9832 | 0.4570 | 1.3770 | NA | 1.0253 | 1.6779 | 1.8067 | 0.1408 | 1.4887 | NA | 1.0177 | 1.6441 | 0.2016 | 0.7588 | NA | 0.9034 | NA | 0.6832 | 0.9290 | 1.0111 | 1.0226 | 0.8945 | NA | 1.1621 | 0.0926 | 0.8129 | 0.9790 | 0.9703 | NA | 1.0007 | 1.4114 | 1.3933 | 1.3036 | 1.1584 | NA | 0.9184 | 1.4216 | 1.3543 | 1.1600 |
| Malic acid | 0.5660 | NA | 0.4262 | 0.8233 | 1.0927 | 1.8960 | 0.9242 | NA | 0.4835 | 1.0394 | 1.4613 | 0.6082 | 1.5242 | NA | 1.9243 | 2.4260 | 0.3128 | 1.8265 | 0.7392 | NA | 1.2660 | 1.6817 | 2.0583 | 0.0180 | NA | 0.0777 | NA | 0.0077 | 0.4211 | 0.8866 | 0.4748 | 0.1196 | NA | 0.9111 | 0.9465 | 1.0886 | 0.6587 | 1.5712 | NA | 0.1254 | 1.3075 | 1.3874 | 0.4605 | 1.4483 | NA | 1.4008 | 1.0856 | 1.5732 | 0.9503 |
| NAD | 0.8774 | NA | 1.0145 | 0.9729 | 1.0977 | 1.1100 | 1.3131 | NA | 0.8941 | 0.9947 | 1.1786 | 0.4204 | 1.0576 | NA | 1.1804 | 1.5442 | 1.5813 | 1.0809 | 1.2244 | NA | 1.2895 | 1.3061 | 1.5428 | 0.8549 | NA | 0.8942 | NA | 0.7071 | 1.1593 | 1.0658 | 0.9766 | 0.0902 | NA | 0.7367 | 0.9495 | 1.0899 | 0.7843 | 0.8429 | NA | 0.7249 | 0.9127 | 1.0530 | 0.9108 | 0.8919 | NA | 0.0808 | 1.2654 | 1.2419 | 1.0866 |
| NADH | 0.8831 | NA | 0.5776 | 1.0338 | 6.4412 | 0.3291 | 0.4049 | NA | 0.9102 | 1.5309 | 0.4239 | 0.0756 | 0.9427 | NA | 0.3709 | 0.6188 | 0.2461 | 0.2017 | 0.8088 | NA | 1.1752 | 1.1627 | 2.4081 | 0.4250 | NA | 0.0441 | NA | 0.5889 | 0.2017 | 0.3568 | 1.1043 | 3.1306 | NA | 0.3715 | 2.8075 | 0.6318 | 2.5245 | 1.8122 | NA | 0.3921 | 0.1622 | 0.1920 | 0.0641 | 3.1067 | NA | 0.5722 | 0.2877 | 0.0107 | 0.6684 |
| NADP | 0.1318 | NA | 0.7083 | 0.6488 | 1.1920 | 1.6801 | 0.1223 | NA | 1.2345 | 0.8401 | 1.1296 | 0.4194 | 0.0784 | NA | 1.0825 | 2.0601 | 1.5447 | 1.4310 | 1.1611 | NA | 1.4651 | 2.8952 | 0.2595 | 0.8297 | NA | 1.1029 | NA | 0.0736 | 0.6368 | 0.7720 | 0.8899 | 1.1988 | NA | 0.5768 | 1.3722 | 0.6084 | 1.1662 | 1.1452 | NA | 0.7911 | 1.5293 | 0.7974 | 1.1572 | 1.5027 | NA | 1.0378 | 0.1389 | 1.5734 | 1.0152 |
| NADPH | 1.4373 | NA | 0.6081 | 0.4689 | 0.1209 | 1.5469 | 1.2524 | NA | 1.2236 | 0.6717 | 1.3450 | 0.3701 | 0.7362 | NA | 1.2806 | 2.2544 | 1.7563 | 1.2889 | 1.0552 | NA | 0.1328 | 2.4811 | 0.2254 | 1.0360 | NA | 1.0068 | NA | 0.0828 | 0.6824 | 0.6159 | 0.7314 | 0.0136 | NA | 0.4809 | 1.3056 | 0.7685 | 1.2313 | 1.2324 | NA | 0.7410 | 1.5745 | 0.6002 | 1.1132 | 1.7691 | NA | 1.1028 | 1.3902 | 1.2793 | 0.9863 |
| Oxidized glutathione | 0.8684 | NA | 0.2771 | 0.6343 | 1.3834 | 1.8987 | 0.0589 | NA | 0.1085 | 0.9016 | 1.0451 | 0.4329 | 0.1970 | NA | 1.7320 | 2.6202 | 1.2974 | 0.8193 | 0.9830 | NA | 1.3030 | 1.9407 | 1.0826 | 0.9883 | NA | 0.1273 | NA | 0.8486 | 0.5027 | 0.6689 | 0.5944 | 1.0111 | NA | 0.0557 | 0.7232 | 1.0755 | 1.3936 | 3.6944 | NA | 1.1379 | 0.8808 | 0.0101 | 0.7072 | 1.4803 | NA | 1.1601 | 0.4845 | 1.6900 | 1.1812 |
| Oxoglutaric acid | 1.5346 | NA | 0.9925 | 0.5350 | 0.6733 | 0.8697 | 1.5298 | NA | 1.5266 | 0.4534 | 0.6992 | 0.7093 | 1.3237 | NA | 1.2973 | 1.2008 | 1.6588 | 0.4892 | 1.3752 | NA | 0.9845 | 0.7415 | 0.0814 | 0.9654 | NA | 0.9554 | NA | 1.0914 | 0.3013 | 1.0667 | 1.0446 | 1.1077 | NA | 0.6871 | 0.8005 | 0.1099 | 1.2796 | 1.3336 | NA | 1.3822 | 0.6923 | 0.1613 | 1.8206 | 1.2949 | NA | 1.1741 | 1.0019 | 1.3514 | 1.7020 |
| Pantothenic acid | 0.9740 | NA | 0.8195 | 0.5114 | 0.5877 | 1.0882 | 2.0721 | NA | 0.9458 | 0.6710 | 0.7179 | 0.5285 | 1.7736 | NA | 1.3440 | 1.3902 | 1.4439 | 0.8995 | 1.4397 | NA | 1.0295 | 1.1215 | 1.0426 | 0.8605 | NA | 1.0181 | NA | 0.9621 | 0.0175 | 0.0818 | 0.7263 | 0.9855 | NA | 2.0573 | 0.2277 | 0.9532 | 0.0852 | 1.4618 | NA | 1.6690 | 0.8878 | 1.5058 | 1.6739 | 1.4092 | NA | 1.3723 | 0.4313 | 1.0970 | 0.1163 |
| Pyroglutamic acid | 0.8454 | NA | 0.8195 | 0.6945 | 0.8787 | 0.9386 | 1.3916 | NA | 0.7649 | 0.8105 | 1.0320 | 0.7268 | 1.1170 | NA | 1.1427 | 1.1884 | 1.2130 | 0.9210 | 1.1373 | NA | 1.1129 | 1.2515 | 1.2462 | 0.0897 | NA | 1.3096 | NA | 1.2519 | 0.7892 | 0.1107 | 0.7441 | 1.2023 | NA | 2.0424 | 0.7064 | 1.0549 | 0.8048 | 1.2287 | NA | 1.8832 | 0.8929 | 0.1048 | 1.0161 | 1.3353 | NA | 1.8815 | 0.1042 | 0.9865 | 1.2281 |
| S-Adenosylhomocysteine | 0.0264 | NA | 0.9101 | 1.2044 | 1.1754 | 1.4082 | 1.0021 | NA | 0.5194 | 0.1520 | 0.8694 | 0.8669 | 1.6164 | NA | 1.4237 | 0.1630 | 2.4487 | 1.4188 | 1.4004 | NA | 1.1004 | NA | 1.5874 | 1.0346 | NA | 0.8717 | NA | 0.8932 | 1.3379 | 0.8156 | 1.0214 | 1.0581 | NA | 1.2281 | 1.1422 | 0.8807 | 0.8651 | 0.7849 | NA | 0.5255 | 0.2263 | 1.3191 | 0.4248 | 1.2244 | NA | 1.1263 | 1.6145 | 0.9542 | 0.3584 |
| Sorbitol | 1.1094 | NA | 0.1004 | 0.0513 | 0.4788 | 0.0755 | 0.8304 | NA | 0.9168 | 0.4533 | 0.3920 | 0.3323 | 0.8114 | NA | 2.0557 | 1.3918 | 0.5719 | 0.5708 | 0.6881 | NA | 1.8578 | 1.0848 | 0.9575 | 0.9096 | NA | 1.4103 | NA | 1.2692 | 1.1890 | 0.4890 | 1.0759 | 2.4477 | NA | 1.5549 | 1.1003 | 0.7123 | 0.5984 | 1.3213 | NA | 1.7950 | 0.9772 | 0.6396 | 0.5572 | 5.2238 | NA | 0.8310 | 0.0788 | 0.5159 | 0.5737 |
| Succinic acid | 0.8140 | NA | 0.5689 | 0.8468 | 0.8235 | 1.0786 | 0.0612 | NA | 0.0455 | 0.9425 | 1.1109 | 0.3674 | 0.7902 | NA | 1.0647 | 1.6592 | 2.0165 | 1.6047 | 0.8321 | NA | 1.5873 | 1.3134 | 1.8592 | 1.3422 | NA | 0.8900 | NA | 0.9151 | 0.4028 | 0.5205 | 0.6779 | 1.1728 | NA | 1.4053 | 0.0115 | 0.7910 | 0.7202 | 1.6687 | NA | 1.3068 | 1.0681 | 0.5685 | 0.8358 | 1.2467 | NA | 1.2090 | 2.1410 | 0.6652 | 1.0542 |
| Trehalose | 0.5503 | NA | 0.8077 | 1.3541 | 1.3864 | 1.9168 | 1.0817 | NA | 0.7266 | 1.3826 | 1.1034 | 0.1082 | 0.9383 | NA | 1.1300 | 2.0666 | 2.0780 | 0.1682 | 0.9350 | NA | 0.9440 | 0.1510 | 1.9092 | 0.9336 | NA | 0.4703 | NA | 0.3282 | 0.0950 | 0.8848 | 0.6963 | 0.4751 | NA | 1.0090 | 1.1853 | 0.5076 | 0.0769 | 0.5183 | NA | 3.2236 | 2.8596 | 1.0249 | 1.1087 | 0.3670 | NA | 0.4886 | 1.7808 | 0.5776 | 0.6510 |
| Uracil | 0.6251 | NA | 0.7101 | 0.5087 | 0.5054 | 1.3533 | 1.2400 | NA | 0.6712 | 0.5843 | 0.4850 | 0.3384 | 0.5944 | NA | 0.6180 | 0.4970 | 0.4660 | 0.7109 | 1.0319 | NA | 0.9623 | 0.7139 | 1.0086 | 0.6057 | NA | 1.6526 | NA | 1.3349 | 2.1205 | 0.2518 | 1.5815 | 1.8469 | NA | 1.8102 | 2.2464 | 0.0490 | 1.9059 | 1.1185 | NA | 0.5300 | 2.1696 | 0.1558 | 0.8636 | 1.8338 | NA | 1.2970 | 2.5095 | 0.3323 | 0.1602 |
| Uridine 5^-monophosphate | 1.2464 | NA | 0.5120 | 0.6387 | 0.1359 | 3.7342 | 0.1387 | NA | 0.7999 | 0.7242 | 1.7438 | 0.7604 | 0.2590 | NA | 0.6071 | 2.3143 | 1.2136 | 1.9257 | 0.6441 | NA | 1.3807 | 2.8651 | 2.3587 | 1.8186 | NA | 0.8965 | NA | 0.4529 | 0.8813 | 0.3900 | 0.4248 | 0.9367 | NA | 0.1976 | 0.8755 | 0.2743 | 0.5847 | 0.1790 | NA | 0.2271 | 2.6956 | 0.1427 | 0.7024 | 1.2322 | NA | 0.5992 | 1.1695 | 0.7930 | 0.5237 |
| Uridine diphosphate glucose | 0.6326 | NA | 0.6248 | 0.1108 | 0.0944 | 2.9221 | 0.6911 | NA | 0.4951 | 1.5690 | 1.1975 | 0.7979 | 1.6654 | NA | 1.2541 | 2.6569 | 2.5272 | 1.9472 | 1.0486 | NA | 0.9775 | 1.6213 | 2.1970 | 0.1589 | NA | 0.0544 | NA | 0.5153 | 0.8799 | 0.7603 | 0.7529 | 0.7796 | NA | 0.6121 | 0.9050 | 0.7286 | 0.0838 | 0.7924 | NA | 0.8550 | 1.1419 | 1.2504 | 1.0750 | 0.8695 | NA | 0.7041 | 0.1037 | 1.0379 | 0.9087 |
| Xanthosine | 0.4452 | NA | 1.0148 | 1.5708 | 2.1759 | 0.0315 | 0.0800 | NA | 0.7284 | 1.4047 | 1.1167 | 0.0632 | 0.6639 | NA | 0.1030 | 0.5911 | 0.1404 | 0.2967 | 1.7863 | NA | 1.9645 | 1.0243 | 1.4241 | 0.2438 | NA | 2.0878 | NA | 0.0838 | 0.7579 | 1.0235 | 1.9254 | 2.9084 | NA | 1.3515 | 1.4495 | 0.5695 | 1.4520 | 0.0345 | NA | 0.4364 | 0.5166 | 0.9270 | 0.1114 | 2.9543 | NA | 0.0086 | 2.4579 | 0.6203 | 1.4541 |
Factors:
| F1 | Exposure time:Month | Nanomaterial:C | Replicate:N1 |
| F2 | Exposure time:Month | Nanomaterial:C- | Replicate:N1 |
| F3 | Exposure time:Month | Nanomaterial:C | Replicate:N2 |
| F4 | Exposure time:Month | Nanomaterial:C | Replicate:N3 |
| F5 | Exposure time:Month | Nanomaterial:C | Replicate:N4 |
| F6 | Exposure time:Month | Nanomaterial:C | Replicate:N5 |
| F7 | Exposure time:Month | Nanomaterial:FLG | Replicate:N1 |
| F8 | Exposure time:Month | Nanomaterial:FLG- | Replicate:N1 |
| F9 | Exposure time:Month | Nanomaterial:FLG | Replicate:N2 |
| F10 | Exposure time:Month | Nanomaterial:FLG | Replicate:N3 |
| F11 | Exposure time:Month | Nanomaterial:FLG | Replicate:N4 |
| F12 | Exposure time:Month | Nanomaterial:FLG | Replicate:N5 |
| F13 | Exposure time:Month | Nanomaterial:GO g | Replicate:N1 |
| F14 | Exposure time:Month | Nanomaterial:GO g- | Replicate:N1 |
| F15 | Exposure time:Month | Nanomaterial:GO g | Replicate:N2 |
| F16 | Exposure time:Month | Nanomaterial:GO g | Replicate:N3 |
| F17 | Exposure time:Month | Nanomaterial:GO g | Replicate:N4 |
| F18 | Exposure time:Month | Nanomaterial:GO g | Replicate:N5 |
| F19 | Exposure time:Month | Nanomaterial:GO | Replicate:N1 |
| F20 | Exposure time:Month | Nanomaterial:GO- | Replicate:N1 |
| F21 | Exposure time:Month | Nanomaterial:GO | Replicate:N2 |
| F22 | Exposure time:Month | Nanomaterial:GO | Replicate:N3 |
| F23 | Exposure time:Month | Nanomaterial:GO | Replicate:N4 |
| F24 | Exposure time:Month | Nanomaterial:GO | Replicate:N5 |
| F25 | Exposure time:- | Nanomaterial:- | Replicate:- |
| F26 | Exposure time:Week | Nanomaterial:C | Replicate:N1 |
| F27 | Exposure time:Week | Nanomaterial:C- | Replicate:N1 |
| F28 | Exposure time:Week | Nanomaterial:C | Replicate:N2 |
| F29 | Exposure time:Week | Nanomaterial:C | Replicate:N3 |
| F30 | Exposure time:Week | Nanomaterial:C | Replicate:N4 |
| F31 | Exposure time:Week | Nanomaterial:C | Replicate:N5 |
| F32 | Exposure time:Week | Nanomaterial:FLG | Replicate:N1 |
| F33 | Exposure time:Week | Nanomaterial:FLG- | Replicate:N1 |
| F34 | Exposure time:Week | Nanomaterial:FLG | Replicate:N2 |
| F35 | Exposure time:Week | Nanomaterial:FLG | Replicate:N3 |
| F36 | Exposure time:Week | Nanomaterial:FLG | Replicate:N4 |
| F37 | Exposure time:Week | Nanomaterial:FLG | Replicate:N5 |
| F38 | Exposure time:Week | Nanomaterial:GO g | Replicate:N1 |
| F39 | Exposure time:Week | Nanomaterial:GO g- | Replicate:N1 |
| F40 | Exposure time:Week | Nanomaterial:GO g | Replicate:N2 |
| F41 | Exposure time:Week | Nanomaterial:GO g | Replicate:N3 |
| F42 | Exposure time:Week | Nanomaterial:GO g | Replicate:N4 |
| F43 | Exposure time:Week | Nanomaterial:GO g | Replicate:N5 |
| F44 | Exposure time:Week | Nanomaterial:GO | Replicate:N1 |
| F45 | Exposure time:Week | Nanomaterial:GO- | Replicate:N1 |
| F46 | Exposure time:Week | Nanomaterial:GO | Replicate:N2 |
| F47 | Exposure time:Week | Nanomaterial:GO | Replicate:N3 |
| F48 | Exposure time:Week | Nanomaterial:GO | Replicate:N4 |
| F49 | Exposure time:Week | Nanomaterial:GO | Replicate:N5 |
