Data for (Study ST002199)

(Analysis AN003599)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Metabolite	F1	F2	F3	F4	F5	F6
12,13-DiHOME	0.7893	1.3553	1.3771	1.7736	0.0705	0.0806
1-methyladenosine	0.7763	0.6117	0.8225	0.8248	1.5480	1.4167
1-methylhistidine	0.8588	0.7410	1.0849	1.2002	1.0709	1.0442
1-methylnicotinamide	1.6677	1.5329	1.0403	1.1917	0.3175	0.2498
2/3-phosphoglycerate	1.3419	1.2123	0.8432	1.0757	0.8516	0.6753
2-aminoheptanoate	0.7296	0.6262	1.3018	1.1275	0.9991	1.2158
2-hydroxyglutarate	0.6452	0.7432	0.6166	0.7037	1.6542	1.6371
2-methyl-3-hydroxybutyrate	0.7795	0.7970	0.6899	0.7783	1.4356	1.5197
2-oxoglutarate	0.4532	0.4932	0.4423	0.4776	2.1525	1.9812
3-methylhistidine	0.9056	0.7688	1.0292	1.2073	1.0251	1.0640
3-phosphoserine	0.3246	0.2789	0.2274	0.1859	2.5932	2.3901
4-aminobutyrate	1.1959	1.0060	0.5665	0.5120	1.3346	1.3851
4-hydroxyphenylpyruvate	0.7119	0.6436	1.0456	1.1576	1.2890	1.1523
4-hydroxyproline	1.0221	0.9948	0.9620	1.0621	0.9429	1.0161
4-imidazolone-5-propionate	0.5713	0.5320	0.6175	0.6279	1.9597	1.6916
4-pyridoxate	1.5510	1.3189	1.2154	1.2118	0.3582	0.3447
5-hydroxyindoleacetate	0.6794	0.6383	0.9256	0.8377	1.4953	1.4238
5-methylcytidine	1.2058	0.9932	1.1525	1.2238	0.7532	0.6714
acetylcarnitine	1.3407	1.1642	1.0344	1.0820	0.7436	0.6350
acetyl-CoA	1.3159	1.1940	0.9127	1.1826	0.7465	0.6484
aconitate	0.2747	0.3038	0.3052	0.3252	2.7180	2.0730
acrylate	1.4574	1.2818	1.5135	1.6417	0.0562	0.0494
adenosine	1.3245	0.9293	1.3239	1.2768	0.6271	0.5184
ADP	1.3564	1.0342	0.9782	1.1139	0.8468	0.6705
ADP-ribose	1.3530	1.1937	0.9603	1.0740	0.7152	0.7038
Alanine	0.8524	0.7706	0.8860	0.9303	1.3041	1.2566
Alanyl-Glutamine	0.8786	0.6572	1.2288	1.2627	1.0564	0.9162
Alanylisoleucine	0.9915	0.7701	1.1021	1.3652	0.9479	0.8232
allantoin	0.8265	0.9909	0.9897	1.1718	1.0930	0.9281
AMP	0.9153	0.8380	1.0963	1.1093	1.0932	0.9479
anserine	1.1704	1.1294	1.3631	1.3913	0.4438	0.5021
arachidonate	1.4193	1.2777	1.1006	1.3178	0.4148	0.4697
arginine	1.0279	0.9054	1.2790	1.3556	0.7322	0.6999
argininosuccinate	1.1895	1.0594	1.8943	1.8292	0.0139	0.0137
asparagine	1.1841	0.9415	1.1478	1.2263	0.8201	0.6802
aspartate	0.5466	0.4840	0.5773	0.6414	1.9206	1.8300
ATP	1.4729	0.8831	0.8817	1.1111	0.9676	0.6836
benzaldehyde	0.7816	0.6733	1.1035	1.2247	1.1381	1.0789
beta-alanine	1.1244	1.1600	0.9075	0.9843	0.9719	0.8520
beta-aspartyl-glycine	1.0996	1.0131	1.0367	1.1455	0.9088	0.7962
betaine	0.5279	0.5003	1.3257	1.6010	1.0285	1.0165
bis(2-ethylhexyl)phthalate	1.1160	1.0679	1.0813	1.2019	0.8699	0.6629
C3-Carnitine	0.1793	0.1978	0.2967	0.3077	2.6091	2.4096
C4-Carnitine	1.0350	1.0465	0.5891	0.6772	1.3681	1.2842
C5-carnitine	0.3538	0.3075	0.3016	0.3279	2.3445	2.3647
carnosine	1.0904	1.2026	1.2580	1.3265	0.5840	0.5385
Choline	1.4464	1.6049	1.0978	1.3518	0.2381	0.2611
cinnamate	0.7497	0.6504	1.1013	1.2499	1.1578	1.0909
citicoline	1.4768	1.2610	0.8262	0.8988	0.8161	0.7211
citrulline	0.8603	0.7296	0.9756	0.9433	1.3044	1.1867
CMP-N-Acetylneuraminate	0.6212	0.5062	1.1789	1.2518	1.3205	1.1214
Coenzyme A	1.4789	1.0513	1.0705	1.3835	0.5946	0.4212
creatine	0.7167	0.6093	1.1102	1.0485	1.3159	1.1993
creatinine	1.0365	0.9335	0.9957	1.0286	1.0552	0.9506
cyclic ADP-ribose	1.0529	0.9895	0.9788	1.0765	1.0096	0.8926
cyclic AMP	1.3964	1.3008	0.8148	0.9586	0.8551	0.6743
cystathionine	0.8947	0.9197	0.6105	0.8538	1.2929	1.4283
cysteinylglycine	1.1383	1.2385	0.9885	1.2852	0.6482	0.7014
cystine	1.2194	1.7348	0.8708	1.3016	0.3875	0.4859
cytidine	1.0571	0.9126	0.9114	1.0030	1.1672	0.9487
cytidine monophosphate	0.7921	0.6695	0.9647	0.9792	1.4010	1.1935
cytosine	1.0415	0.9231	0.8891	0.9471	1.1950	1.0041
deoxycholate	0.6956	0.6483	0.6262	3.2641	0.3719	0.3939
deoxycytidine	0.8914	0.8648	1.0127	1.1487	1.0594	1.0230
dethiobiotin	0.9646	0.7871	0.9248	0.9691	1.2336	1.1208
didecyldimethylammonium	0.5259	0.6745	1.9830	1.6081	0.7662	0.4423
diethanolamine	0.4043	0.2933	0.4610	0.6298	1.7114	2.5002
dihydrobiopterin	1.0738	1.0291	1.1287	1.2543	0.7648	0.7493
dihydroorotate	1.4403	1.1447	0.7264	0.7461	0.8556	1.0869
dihydroxyacetone phosphate	1.3048	1.2923	0.9530	0.9789	0.7691	0.7019
dodecyl sulfate	0.9911	0.9773	1.0817	1.1586	0.8288	0.9624
erythritol	1.0477	0.9839	1.0524	1.1923	0.9203	0.8035
erythronate/threonate	1.0412	0.9436	0.7905	0.8679	1.2470	1.1098
FAD	0.9967	0.9699	0.9978	1.3859	0.8980	0.7517
fructose 6-phosphate	1.1963	1.1982	1.0921	1.3650	0.5767	0.5717
fumarate	1.4649	1.2834	1.4960	1.6432	0.0586	0.0539
gamma-glutamylcysteine	0.3656	0.4743	0.9828	1.7977	1.2022	1.1774
gamma-glutamylglutamate	0.8763	0.8246	0.9350	1.0719	1.2009	1.0914
gamma-glutamylglycine	0.8779	0.5503	0.4907	0.3341	2.0869	1.6600
gamma-glutamylhistidine	1.0504	1.0232	0.8291	0.8364	1.1953	1.0656
gamma-glutamylleucine	0.4277	0.2339	0.4424	0.2961	2.5461	2.0538
gamma-glutamylvaline	0.3348	0.2133	0.3990	0.2880	2.6378	2.1272
GDP	1.6805	1.0125	0.9318	1.1926	0.6714	0.5113
GDP-fucose	1.2988	1.1191	0.9518	1.1090	0.8469	0.6744
GDP-hexose	1.3068	1.1194	1.0903	1.3355	0.6525	0.4954
glucose	1.0716	1.1033	1.1651	1.3164	0.6095	0.7341
glucose 6-phosphate	1.2136	1.1386	1.1153	1.4272	0.5145	0.5908
glucuronate	1.1482	1.4519	0.9721	1.1390	0.7024	0.5863
glutamate	0.5761	0.4627	0.5870	0.5356	2.0859	1.7528
glutamine	1.1877	1.0302	1.2621	1.2746	0.6194	0.6261
glutathione reduced	1.1814	1.2333	1.0270	1.2572	0.6323	0.6687
glyceraldehyde 3-phosphate	0.8582	0.9323	0.9853	1.2102	1.0452	0.9687
glycerol 2-phosphate	0.8089	0.6637	0.8105	0.7075	1.6750	1.3344
glycerol 3-phosphate	1.0933	1.0264	1.3422	1.5124	0.5892	0.4365
glycerophosphocholine	0.9249	0.7520	0.8747	0.8179	1.4238	1.2067
Glycine	1.3660	1.2357	0.9904	1.1273	0.6867	0.5939
Glycyl-Aspartate	0.8761	0.7679	0.9440	0.9995	1.2847	1.1278
Glycyl-Glutamate	0.8773	0.5501	0.4907	0.3340	2.0872	1.6608
Glycyl-Proline	1.0241	0.8802	1.0791	1.1478	0.9611	0.9077
Glycyl-Serine	0.6965	0.6591	1.1076	1.1098	1.2161	1.2109
GMP	0.9146	0.7504	1.0230	1.0961	1.1338	1.0820
guanosine	1.1446	0.8742	1.0349	0.9871	1.0702	0.8890
hexadecanoylcarnitine	1.6882	1.1704	0.6590	0.6864	0.9352	0.8608
hexanoate	0.9994	1.0247	0.9559	0.9922	0.9745	1.0533
hexanoylcarnitine	1.6033	1.5511	0.8850	0.9532	0.5020	0.5054
hexitol	1.1301	0.9350	1.1327	0.8262	1.0279	0.9481
hexosamine phosphates	1.1177	0.9407	0.8113	0.7335	1.2684	1.1284
histidine	0.8992	0.8608	1.0917	1.2378	0.9277	0.9828
Histidinyl-Isoleucine	0.9293	0.7661	1.0526	1.2740	1.0389	0.9392
Histidinyl-Valine	0.8937	0.7846	0.9730	1.2430	1.1052	1.0005
homoarginine	0.9813	0.8526	1.3187	1.4030	0.7272	0.7172
homocitrulline	0.6165	0.5479	0.7490	0.8637	1.6704	1.5524
hydroquinone	1.2189	0.9651	1.0856	1.0196	0.8979	0.8129
hydroxybutyrylcarnitine	0.7275	0.7856	1.3401	1.5657	0.8410	0.7402
hydroxyphenyllactate	0.4634	0.3963	1.0186	0.9837	1.6971	1.4410
hypotaurine	1.1589	1.1165	0.9621	1.0419	0.9318	0.7889
hypoxanthine	0.9960	1.2370	0.7103	2.0177	0.4676	0.5714
IMP	1.1256	1.3878	0.6112	1.6597	0.5476	0.6681
Indole-3-acrylate	0.7096	0.6313	1.0782	1.2375	1.2181	1.1253
Indole-3-aldehyde	0.7041	0.6350	1.0664	1.2308	1.2374	1.1264
Indole-3-lactate	0.7853	0.7705	1.1207	1.2593	1.0815	0.9827
Indole-3-propionate	0.7666	0.6635	1.0946	1.2319	1.1414	1.1020
inosine	1.2574	1.3388	0.5856	2.1310	0.3594	0.3278
inositol	1.3094	1.4533	0.9795	1.0094	0.6189	0.6295
isoleucine	0.8683	0.7716	1.0771	1.2203	1.0647	0.9980
ketoleucine	0.9762	0.9462	0.8250	0.9418	1.1513	1.1595
ketovaline	0.8855	1.0245	0.7711	0.7979	1.1581	1.3629
kynurenine	0.7148	0.6217	0.9063	0.9776	1.4031	1.3765
lactate	1.1866	1.2723	1.0506	1.3556	0.5725	0.5624
L-Cartinine	1.4562	1.2930	0.9118	1.0073	0.6964	0.6353
leucine	0.9123	0.7578	1.1835	1.2755	0.9691	0.9018
Leucyl-Glycine	1.0065	0.7910	1.0969	1.3223	0.9296	0.8536
Leucyl-Proline	0.6234	0.5376	0.7865	0.8880	1.6574	1.5072
Leucyl-Serine	0.9121	0.7218	1.0341	1.2906	1.0744	0.9669
Leucyl-Valine	1.0732	0.7760	1.1548	1.4539	0.8228	0.7194
linoleate	1.7114	1.3967	0.9981	0.7886	0.5066	0.5986
lysine	0.9694	0.8581	1.3800	1.5106	0.6526	0.6293
malate	0.2087	0.2871	0.2992	0.3767	2.4795	2.3488
methionine	0.9215	0.7115	1.2281	1.2870	0.9698	0.8820
methionine sulfone	0.9710	0.7897	1.1143	1.1982	0.9674	0.9594
methionine sulfoxide	0.8957	0.6578	1.1387	0.9538	1.2298	1.1242
methylimidazoleacetate	1.0637	1.0014	1.1653	1.1356	0.8477	0.7862
methylthioadenosine	1.2005	1.0544	0.8567	0.8626	1.1082	0.9176
myristate	1.1009	1.0477	0.8958	1.3992	0.7525	0.8038
myristoylcarnitine	1.3166	1.1301	0.6357	0.6138	1.2427	1.0611
N2-Acetylornithine	0.6925	0.5593	0.9992	1.0481	1.4102	1.2909
N2-gamma-Glutamylglutamine	0.9396	0.8505	1.0642	1.2171	0.9683	0.9603
N6-acetyllysine	1.0465	0.9630	1.1625	1.2985	0.7760	0.7536
N6-methyllysine	1.1452	1.2106	1.0996	1.1060	0.6576	0.7810
N6,N6,N6-trimethyllysine	1.0814	0.8930	1.6714	1.7779	0.3075	0.2688
N-acetylalanine	0.8813	0.8743	0.6105	0.6835	1.5486	1.4018
N-acetylaspartate	0.4765	0.4824	0.5761	0.5924	1.8122	2.0603
N-acetylaspartylglutamate	0.3120	0.3068	0.5712	0.6006	2.1657	2.0437
N-acetylglucosamine	1.4076	1.0481	0.9315	0.9584	0.8634	0.7911
N-acetylglutamate	0.5361	0.5020	0.5620	0.5621	2.0459	1.7920
N-acetylglutamine	1.2676	1.0034	0.9821	0.9666	0.9338	0.8466
N-acetylhistidine	0.6188	0.9016	1.1271	1.3182	0.8414	1.1929
N-acetylleucine	0.8601	0.7741	1.1718	1.1983	1.0429	0.9529
N-acetylmethionine	0.9940	0.8881	0.8657	1.0090	1.1683	1.0749
N-acetylneuraminate	1.2543	1.1801	1.0915	1.5171	0.4965	0.4605
N-acetylputrescine	0.6844	0.5000	0.5043	0.3144	2.1851	1.8118
N-acetylserine	0.7736	0.6697	0.6559	0.7702	1.6316	1.4991
N-acetylthreonine	0.8303	0.7277	0.7016	0.7594	1.5933	1.3877
NAD	1.0499	0.9865	0.9628	1.0724	1.0185	0.9098
NADH	0.7116	1.0174	1.2698	2.4675	0.4855	0.0483
NADP	1.3713	1.0212	0.9953	1.1345	0.7877	0.6899
NADPH	1.0119	1.0670	0.7762	1.2278	1.1759	0.7411
N-alpha-acetyllysine	1.4258	1.6945	0.6710	0.8395	0.7198	0.6493
N-carbamoylaspartate	1.0656	1.3397	0.5211	0.5777	1.2721	1.2239
nervonate	1.1134	1.0121	0.5385	0.3759	1.2336	1.7265
nicotinamide	0.9687	0.8419	0.8620	1.0556	1.1310	1.1409
N,N-dimethylarginine	1.0580	0.8480	1.3262	1.3899	0.6803	0.6976
oleate	1.2559	1.2078	0.8838	0.8651	0.8092	0.9782
ophthalmate	0.8422	0.4013	0.4288	0.2646	2.1262	1.9368
ornithine	0.5765	0.5950	1.0194	1.0210	1.3890	1.3991
orotate	1.0229	0.8305	0.7271	0.8830	0.9106	1.6259
oxalate	1.0897	0.9496	1.0185	1.0773	0.9484	0.9164
oxidized glutathione	1.0869	1.2342	1.0106	1.3004	0.6696	0.6983
palmitate	0.7233	1.3946	1.2595	1.4220	0.5521	0.6486
palmitoleate	1.7643	1.4956	0.7752	0.6955	0.5881	0.6812
palmitoylethanolamide	0.8300	0.8026	0.9787	1.0137	1.0770	1.2980
palmitoyl sphingomyelin	0.8734	0.9476	0.7969	0.6807	1.1075	1.5940
pantothenate	0.8624	0.6812	0.9840	0.8571	1.4056	1.2097
pentitol	1.1005	0.9713	0.6506	0.6041	1.4535	1.2200
pentose phosphate	1.5887	1.5017	0.8340	0.9704	0.5913	0.5139
phenylalanine	0.7576	0.6574	1.0847	1.2313	1.1706	1.0984
phenylalanylalanine	1.0352	0.8598	1.0157	1.2251	1.0042	0.8600
phenylalanylproline	0.6087	0.5596	0.7599	0.9102	1.6773	1.4844
phosphocreatine	0.8340	0.6418	0.9571	0.8582	1.4681	1.2408
phosphoenolpyruvate	1.0870	0.9972	0.6768	1.0234	1.0539	1.1616
phosphorylcholine	1.0563	0.9090	1.0042	1.0976	0.9802	0.9527
proline	0.4277	0.3704	0.6702	0.7454	1.9633	1.8229
Prolyl-Alanine	1.0718	0.8937	1.0402	1.1481	0.9658	0.8804
pseudouridine	0.9408	0.8937	0.9562	1.0753	1.0924	1.0414
pyridoxal	1.1470	0.9702	1.0076	1.1151	0.9353	0.8248
pyridoxine	1.0598	0.9586	0.9844	1.0915	1.0038	0.9019
pyroglutamate	1.0981	1.1054	1.0319	1.2089	0.8191	0.7366
pyruvate	0.5462	0.5101	0.6584	0.9847	1.6160	1.6846
quinoline	0.7096	0.6652	1.0557	1.2080	1.2327	1.1288
(R)C(S)S-alliin	0.6929	0.6340	0.9351	0.9589	1.5118	1.2674
riboflavin	0.7716	0.9540	0.8708	1.1522	1.1355	1.1159
Ribothymidine	1.0729	1.1240	1.0098	1.2661	0.8136	0.7136
S-(2-succinyl)cysteine	1.3346	1.4718	1.2839	1.8953	0.0071	0.0072
S-adenosylhomocysteine	0.8615	0.7076	0.8527	0.6664	1.5053	1.4064
S-adenosylmethionine	1.1869	1.0596	0.9719	0.9566	0.9626	0.8624
S-allylcysteine	1.7168	1.8405	0.6115	1.3687	0.2257	0.2368
sarcosine	0.8233	1.4599	1.0203	0.7086	0.9764	1.0115
sedoheptulose 7-phosphate	1.0226	1.0916	0.8216	0.8829	1.1527	1.0286
serine	1.3481	1.2659	1.2148	1.2186	0.5022	0.4505
Serylalanine	0.7682	0.6309	0.9263	0.9157	1.4646	1.2943
sphinganine	0.7273	0.7382	0.8477	0.8422	1.2581	1.5865
stearate	0.6922	1.4449	1.3430	1.3870	0.4714	0.6614
stearoylethanolamide	0.8903	0.8733	0.8912	0.8475	1.2319	1.2658
succinate	1.2845	1.1503	0.9739	1.1544	0.8467	0.5902
targinine	0.8495	0.7766	1.1568	1.2045	0.9763	1.0363
taurine	1.1164	1.0738	1.0427	1.1043	0.8665	0.7963
threonine	0.9334	0.8742	1.1230	1.1587	0.9648	0.9458
Threoninyl-Glutamine	1.2286	0.8474	1.4286	1.5613	0.4824	0.4518
Threoninyl-Leucine	1.0124	0.6369	1.1669	1.5452	0.8775	0.7611
Threoninyl-Serine	0.8532	0.6529	1.0405	1.2297	1.2165	1.0071
Tiglylcarnitine	0.3611	0.3085	1.8304	1.9605	0.8346	0.7051
tryptophan	0.7137	0.6336	1.0726	1.2365	1.2115	1.1321
tyrosine	0.8195	0.7303	1.1381	1.2975	1.0432	0.9715
UDP	1.2804	0.9911	0.7851	0.9063	1.1432	0.8940
UDP-GlcNAc	1.1737	1.0129	0.9206	0.9237	1.0831	0.8860
UDP-glucose	0.9948	1.0070	0.7671	0.8708	1.2635	1.0967
UDP-glucuronate	1.8412	1.1641	0.8561	1.4786	0.3932	0.2669
UMP	0.9474	0.8520	0.9184	0.9729	1.1920	1.1172
uracil	0.8706	0.8304	0.8864	1.0479	1.2811	1.0836
urate	1.4038	1.6989	0.7626	0.6282	0.7113	0.7953
uridine	0.8635	0.7737	0.9452	0.9899	1.2164	1.2113
urocanate	0.7656	0.5936	0.9593	1.2712	0.4512	1.9591
valine	0.8661	0.7546	1.1313	1.2452	1.0233	0.9795
Valyl-Valine	1.1601	0.8814	1.1438	1.4392	0.7296	0.6459
xanthine	1.1024	1.0189	1.0625	1.0362	0.9240	0.8559
xanthosine monophosphate	1.2223	1.4467	0.8341	1.1825	0.7526	0.5618

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1	Genotype:Fh1-/-CL19 | Treatment:siFoxa2
F2	Genotype:Fh1-/-CL19 | Treatment:siNT
F3	Genotype:Fh1-/-CL1 | Treatment:siFoxa2
F4	Genotype:Fh1-/-CL1 | Treatment:siNT
F5	Genotype:Fh1fl/fl | Treatment:siFoxa2
F6	Genotype:Fh1fl/fl | Treatment:siNT