Data for (Study ST002228)
(Analysis AN003637)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 1,5-Anhydrosorbitol | 0.9925 | 1.0490 | 1.0011 | 0.9338 |
| 1-Hexadecanol | 0.8571 | 1.0289 | 0.8379 | 1.3083 |
| 2,3-Dihydroxybutanedioic acid | 1.0046 | 0.9742 | 0.9718 | 1.0617 |
| 2-Aminoheptanedioic acid | 0.7423 | 1.0900 | 1.2621 | 0.9435 |
| 2-Hydroxy-3-methylbutyric acid | 0.4724 | 0.5032 | 1.7407 | 1.7246 |
| 2-Hydroxybutyric acid | 0.9296 | 1.1621 | 0.8572 | 0.9881 |
| 2-Phosphoglyceric acid | 0.3322 | 0.3916 | 1.0295 | 2.7938 |
| 3-aminoglutaric acid_1 | 1.0105 | 1.0554 | 0.9527 | 0.9484 |
| 3-aminoglutaric acid_2 | 0.9139 | 0.8622 | 1.0946 | 1.2315 |
| 3-Hydroxyanthranilic acid | 0.7535 | 0.7017 | 1.1734 | 1.6126 |
| 3-Hydroxybutyric acid | 1.2918 | 1.0184 | 0.7633 | 0.8194 |
| 3-Hydroxyisovaleric acid | 0.9097 | 0.9281 | 1.1448 | 1.0859 |
| 3-Phosphoglyceric acid | 0.3448 | 0.4103 | 1.1089 | 2.6690 |
| 4-Hydroxybenzoic acid | 0.4278 | 1.6718 | 0.7859 | 0.9469 |
| 4-Hydroxyproline | 0.5934 | 0.6243 | 1.5556 | 1.5627 |
| 5-Aminopentanoic acid | 0.8807 | 0.7642 | 1.2472 | 1.2733 |
| 5-Methoxytryptamine | 1.0397 | 0.9692 | 0.9102 | 1.0841 |
| 7-Methylguanine | 0.9151 | 1.1366 | 0.9418 | 0.9619 |
| Acetoacetic acid | 1.0005 | 1.0005 | 0.9935 | 1.0051 |
| Acetylglycine | 0.7467 | 0.7808 | 1.4199 | 1.2540 |
| Adenine | 0.9462 | 0.9627 | 1.0864 | 1.0426 |
| Adenosine | 0.5305 | 0.7986 | 1.4294 | 1.5054 |
| Adipic acid | 0.9845 | 0.9892 | 1.1409 | 0.8963 |
| Allantoin | 0.8966 | 0.8064 | 1.3153 | 1.1405 |
| Alpha-Hydroxyisobutyric acid | 0.4823 | 0.4928 | 1.7855 | 1.6824 |
| Aminoadipic acid | 0.7363 | 0.9109 | 1.1859 | 1.3023 |
| Arachidonic acid | 1.0547 | 1.0438 | 0.9969 | 0.8630 |
| Azelaic acid | 1.0251 | 0.9334 | 1.0087 | 1.0600 |
| Benzoic acid | 0.9684 | 1.0231 | 0.9465 | 1.0603 |
| Beta-Alanine | 0.3769 | 0.4129 | 1.9040 | 1.8271 |
| Beta-Glycerophosphoric acid | 0.8215 | 0.9130 | 1.0891 | 1.2823 |
| Cadaverine | 0.7717 | 0.7047 | 1.3649 | 1.3923 |
| Capric acid | 0.9575 | 1.0120 | 0.9919 | 1.0464 |
| Caprylic acid | 0.9330 | 1.0606 | 0.9545 | 1.0419 |
| Cholesterol | 1.0387 | 0.9992 | 0.9743 | 0.9753 |
| cis-Aconitic acid | 0.7451 | 1.1162 | 1.2292 | 0.9324 |
| Citramalic acid | 0.9783 | 1.1605 | 0.8917 | 0.8911 |
| Citric acid | 0.7411 | 1.0906 | 1.2574 | 0.9489 |
| Creatinine | 1.0124 | 1.0029 | 0.9970 | 0.9821 |
| D-Alpha-aminobutyric acid | 0.9745 | 1.4764 | 0.6329 | 0.6706 |
| D-Arabitol | 1.0054 | 0.8852 | 1.1219 | 1.0470 |
| D-Fucose | 0.9742 | 0.8445 | 1.1473 | 1.1255 |
| D-Galactose | 0.9554 | 0.7254 | 1.1726 | 1.3079 |
| Dihydrouracil | 0.7925 | 0.8252 | 1.3643 | 1.1804 |
| Dimethylglycine | 0.8352 | 1.0085 | 1.1242 | 1.0824 |
| D-Leucic acid | 0.9093 | 0.8235 | 1.3490 | 1.0427 |
| D-Mannose | 0.9642 | 0.7585 | 1.1514 | 1.2666 |
| Docosahexaenoic acid | 1.0792 | 1.0392 | 0.9742 | 0.8600 |
| Dodecanoic acid | 0.9739 | 0.9061 | 1.1059 | 1.0728 |
| Dopamine | 0.3432 | 2.0489 | 0.5616 | 0.7058 |
| D-Sedoheptulose 7-phosphate | 1.0762 | 0.9806 | 1.0714 | 0.8567 |
| D-Tagatose | 0.9317 | 1.0610 | 1.0230 | 0.9746 |
| D-Threitol | 1.0050 | 0.9824 | 1.1411 | 0.8791 |
| D-Xylitol | 1.0962 | 0.8573 | 1.1964 | 0.8941 |
| D-Xylose | 0.9999 | 1.0377 | 1.0883 | 0.8540 |
| Eicosapentaenoic acid | 1.0399 | 1.0308 | 1.0076 | 0.8920 |
| Elaidic acid | 1.1629 | 1.0248 | 0.9107 | 0.8341 |
| Ethanolamine | 0.9261 | 1.0810 | 0.9988 | 0.9756 |
| Ethylmalonic acid | 1.0256 | 0.9463 | 1.0827 | 0.9654 |
| Fructose 1-phosphate | 0.8687 | 0.5800 | 0.7114 | 2.1078 |
| Fructose 6-phosphate | 0.6694 | 0.3540 | 0.4861 | 2.9452 |
| Fumaric acid | 0.9955 | 0.9096 | 1.0465 | 1.0982 |
| Galacturonic acid | 0.6745 | 0.5948 | 1.5434 | 1.5119 |
| Gamma-Aminobutyric acid | 1.0163 | 0.8769 | 1.1624 | 1.0047 |
| Gluconic acid | 0.9817 | 0.8642 | 1.0704 | 1.1622 |
| Glucose 6-phosphate | 0.6691 | 0.3394 | 0.5830 | 2.8712 |
| Glutamate, gamma-methyl ester | 0.9755 | 1.0585 | 0.9252 | 1.0178 |
| Glutaric acid | 0.9288 | 0.9443 | 1.0857 | 1.0946 |
| Glutathione | 0.8909 | 0.9973 | 1.1126 | 1.0371 |
| Glyceraldehyde | 1.0121 | 0.9882 | 0.9943 | 1.0078 |
| Glyceric acid | 0.7360 | 0.9799 | 0.9721 | 1.4107 |
| Glycerol | 1.0317 | 0.9477 | 1.0704 | 0.9675 |
| Glycerol 3-phosphate | 0.7700 | 0.7472 | 1.2161 | 1.4781 |
| Glycine | 0.8288 | 0.8160 | 1.2455 | 1.2649 |
| Glycolic acid | 0.9797 | 1.0851 | 0.9895 | 0.9070 |
| Glycyl-glycine | 1.0257 | 0.8973 | 1.2087 | 0.9146 |
| Guanine | 0.7852 | 0.9329 | 1.5355 | 0.8539 |
| Guanosine | 0.8247 | 0.9613 | 1.2683 | 1.0248 |
| Heptadecanoic acid | 0.9773 | 1.0328 | 0.9706 | 1.0093 |
| Histamine | 0.6805 | 1.2881 | 0.8042 | 1.1801 |
| Homocysteine | 1.1278 | 0.8507 | 0.9115 | 1.1471 |
| Hydroxylamine | 1.0021 | 0.9641 | 0.9854 | 1.0668 |
| Hydroxyphenyllactic acid | 1.0076 | 0.9523 | 0.9740 | 1.0890 |
| Hydroxypropionic acid | 0.9358 | 0.9943 | 1.0773 | 1.0171 |
| Hypotaurine | 0.7666 | 0.7003 | 1.3875 | 1.3832 |
| Hypoxanthine | 0.9789 | 1.0333 | 1.1432 | 0.8339 |
| Inosine | 1.0306 | 0.9513 | 1.2023 | 0.8315 |
| Isocitric acid | 0.8276 | 1.0031 | 1.3401 | 0.8850 |
| Isomaltose | 0.8283 | 0.6281 | 1.2690 | 1.5302 |
| Itaconic acid | 0.9674 | 0.8998 | 1.0610 | 1.1361 |
| L-2-Hydroxyglutaric acid | 1.1421 | 0.9570 | 1.1418 | 0.7347 |
| Labelled compound_Taurine | 0.9593 | 0.9537 | 1.0845 | 1.0408 |
| Lactitol | 1.1799 | 0.7948 | 1.0570 | 1.0179 |
| L-Alanine | 0.9445 | 0.8914 | 1.1182 | 1.1223 |
| L-Arginine | 0.9491 | 0.9246 | 1.0989 | 1.0846 |
| L-Asparagine | 0.9356 | 0.9306 | 1.1171 | 1.0752 |
| L-Aspartic acid | 1.0110 | 1.0552 | 0.9517 | 0.9491 |
| L-Cystathionine | 0.7928 | 0.7425 | 1.3170 | 1.3543 |
| L-Cysteine | 0.8061 | 0.9864 | 1.1153 | 1.1640 |
| L-Erythrulose | 1.1426 | 0.9399 | 1.0853 | 0.8167 |
| L-Glutamic acid | 1.0256 | 1.0297 | 0.9884 | 0.9321 |
| L-Glutamine | 1.1887 | 0.9118 | 1.0397 | 0.8439 |
| L-Histidine | 1.0476 | 0.6944 | 1.3626 | 1.0489 |
| L-Homoserine | 0.9494 | 0.9526 | 1.0673 | 1.0727 |
| Linoleic acid | 1.1320 | 0.9114 | 1.0682 | 0.8916 |
| L-Isoleucine | 0.8941 | 0.8836 | 1.1450 | 1.1747 |
| L-Kynurenine | 1.2346 | 1.3314 | 0.5813 | 0.5977 |
| L-Lactic acid | 1.0046 | 0.9468 | 1.0963 | 0.9791 |
| L-Leucine | 0.8968 | 0.8650 | 1.1874 | 1.1572 |
| L-Lysine | 0.9344 | 0.8767 | 1.1194 | 1.1571 |
| L-Methionine | 0.9539 | 0.9806 | 1.0284 | 1.0628 |
| L-Phenylalanine | 0.9027 | 0.9297 | 1.1070 | 1.1305 |
| L-Proline | 0.8011 | 0.8553 | 1.2526 | 1.2345 |
| L-Serine | 0.8499 | 0.9162 | 1.1959 | 1.1327 |
| L-Sorbose | 0.7661 | 0.6784 | 1.2376 | 1.5673 |
| L-Threonine | 0.8394 | 0.8867 | 1.1876 | 1.2003 |
| L-Tryptophan | 1.0990 | 0.9904 | 0.9350 | 0.9477 |
| L-Tyrosine | 0.9351 | 0.9073 | 1.1008 | 1.1279 |
| L-Valine | 0.8722 | 0.8635 | 1.1894 | 1.1903 |
| Maleic acid | 1.0443 | 0.8859 | 1.0762 | 1.0397 |
| Malic acid | 1.0549 | 0.8941 | 1.0712 | 1.0181 |
| Maltitol | 1.0114 | 0.7942 | 1.2666 | 1.0552 |
| Mannose 6-phosphate | 0.6813 | 0.3366 | 0.5876 | 2.8545 |
| Mesaconic acid | 0.9383 | 1.2114 | 0.8772 | 0.8809 |
| Methylmalonic acid | 0.9685 | 0.9890 | 1.0956 | 0.9632 |
| Methylsuccinic acid | 1.0380 | 1.0455 | 0.9407 | 0.9388 |
| MG(18:0e/0:0/0:0) | 0.9696 | 1.0238 | 0.9969 | 1.0070 |
| myo-Inositol | 0.9897 | 1.0264 | 0.9765 | 0.9967 |
| N-Acetyl-D-glucosamine | 0.9458 | 1.0177 | 0.9954 | 1.0497 |
| N-Acetylgalactosamine | 0.9447 | 1.0170 | 0.9948 | 1.0529 |
| N-Acetylglutamine | 0.9250 | 0.8695 | 1.1465 | 1.1535 |
| N-Acetyl-L-alanine | 0.9425 | 0.9618 | 1.0653 | 1.0700 |
| N-Acetyl-L-alanine_2 | 0.8962 | 0.8639 | 1.1869 | 1.1602 |
| N-Acetyl-L-aspartic acid | 1.0365 | 0.9670 | 1.0881 | 0.9139 |
| N-Acetylserine | 0.7411 | 0.8101 | 1.3461 | 1.2902 |
| N-Formyl-L-Methionine | 0.9613 | 0.9554 | 1.0775 | 1.0425 |
| Niacinamide | 1.0328 | 0.9582 | 1.0922 | 0.9281 |
| Nicotinic acid | 0.8642 | 0.9626 | 1.0416 | 1.1969 |
| Norvaline | 0.7995 | 0.9768 | 1.0224 | 1.2806 |
| Oleic acid | 1.1823 | 0.9872 | 0.9417 | 0.8349 |
| O-Phosphoethanolamine | 0.8282 | 1.1277 | 0.9921 | 1.0411 |
| Ornithine | 0.9421 | 0.9531 | 1.1124 | 1.0368 |
| Oxalacetic acid | 0.9687 | 0.8763 | 1.1389 | 1.0924 |
| Oxalic acid | 0.9079 | 1.0234 | 1.0112 | 1.0757 |
| Palmitic acid | 1.0267 | 1.0042 | 0.9895 | 0.9685 |
| Palmitoleic acid | 1.1049 | 0.9748 | 0.9816 | 0.9172 |
| Pantothenic acid | 1.2139 | 1.1692 | 0.7107 | 0.7447 |
| Pelargonic acid | 0.9695 | 1.0471 | 0.9657 | 1.0027 |
| Phenylacetic acid | 1.0324 | 1.0517 | 0.9474 | 0.9300 |
| Phenyllactic acid | 0.8480 | 0.9206 | 1.1936 | 1.1307 |
| Phosphoenolpyruvic acid | 0.7747 | 1.0079 | 0.6784 | 1.6099 |
| p-Hydroxyphenylacetic acid | 0.8684 | 0.9860 | 1.0936 | 1.1033 |
| Pimelic acid | 1.0796 | 0.9590 | 1.0356 | 0.9211 |
| p-Octopamine | 0.9599 | 0.8244 | 1.2052 | 1.1174 |
| Psicose_2 | 0.7617 | 0.6416 | 1.2580 | 1.6093 |
| Putrescine | 0.9485 | 0.9143 | 1.2228 | 0.9773 |
| Pyroglutamic acid | 0.9423 | 1.0716 | 0.9989 | 0.9683 |
| Pyruvic acid | 0.9196 | 0.7555 | 1.1626 | 1.3196 |
| Rhamnose | 0.9590 | 0.8017 | 1.2707 | 1.0802 |
| Ribitol | 1.0567 | 0.9271 | 1.0946 | 0.9415 |
| (S)-3-Hydroxyisobutyric acid | 1.1778 | 0.9834 | 0.8611 | 0.9273 |
| Sarcosine | 0.8775 | 0.9666 | 1.1572 | 1.0574 |
| Spermidine | 0.8131 | 0.9404 | 1.2267 | 1.1139 |
| Stearic acid | 0.9673 | 1.0429 | 0.9835 | 0.9943 |
| Succinic acid | 0.7888 | 0.8659 | 1.1642 | 1.3230 |
| Sucrose | 1.2610 | 0.9725 | 0.8619 | 0.8322 |
| Threonic acid | 0.8353 | 0.9994 | 1.0810 | 1.1395 |
| Thymine | 0.8395 | 1.0113 | 1.0511 | 1.1457 |
| Trehalose | 1.1542 | 0.8088 | 1.0313 | 1.0563 |
| Triethanolamine | 0.9625 | 1.0082 | 1.0084 | 1.0290 |
| Tryptamine | 1.2086 | 1.1299 | 0.7538 | 0.7689 |
| Tyramine | 0.9327 | 0.8814 | 1.1170 | 1.1546 |
| Uracil | 0.9722 | 0.9104 | 1.1600 | 1.0145 |
| Urea | 0.8639 | 0.8721 | 1.2176 | 1.1599 |
| Uric acid | 0.7001 | 0.9309 | 1.2169 | 1.2888 |
| Uridine | 0.8831 | 0.9740 | 1.0921 | 1.1037 |
| Xanthine | 0.8692 | 1.0506 | 1.1587 | 0.9381 |
| Xanthosine | 0.7658 | 0.8642 | 1.4936 | 1.0270 |
Factors:
| F1 | Sex:Female | Genotype:ERalpha-knockout |
| F2 | Sex:Female | Genotype:Floxed Control |
| F3 | Sex:Male | Genotype:ERalpha-knockout |
| F4 | Sex:Male | Genotype:Floxed Control |
