Data for (Study ST002031)

(Analysis AN003301)

Values have been normalized by dividing by the sample mean across all metabolites for each experimental condition

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MetaboliteF1F2F3F4F5F6F7F8F9F10F11F12
2^,3^-Cyclic CMP 0.0057 0.0044 0.0069 0.0060 0.0057 0.0060 0.0054 0.0054 0.0055 0.0057 0.0043 0.0044
3^,5^-Cyclic AMP 0.0120 0.0142 0.0108 0.0131 0.0109 0.0197 0.0099 0.0120 0.0152 0.0165 0.0099 0.0176
4-Acetamidobutanoate 0.0240 0.0281 0.0278 0.0261 0.0263 0.0245 0.0216 0.0233 0.0175 0.0217 0.0225 0.0203
5-6-Dihydrothymine 0.0385 0.0343 0.0327 0.0375 0.0348 0.0412 0.0326 0.0332 0.0262 0.0274 0.0309 0.0325
5-6-Dihydrouracil 0.0200 0.0350 0.0102 0.0218 0.0402 0.0184 0.0230 0.0212 0.0164 0.0144 0.0212 0.0323
5-Guanidino-2-oxopentanoate 0.0164 0.0175 0.0169 0.0130 0.0133 0.0193 0.0200 0.0206 0.0144 0.0188 0.0171 0.0233
5-Hydroxyindoleacetate 0.0403 0.0441 0.0375 0.0360 0.0461 0.0501 0.0282 0.0409 0.0274 0.0346 0.0312 0.0494
5-Hydroxyisourate 0.1349 0.1605 0.1310 0.1504 0.1236 0.1482 0.1015 0.1233 0.1037 0.1526 0.1117 0.1399
5-Oxoproline 0.9708 0.9622 0.9319 0.9929 0.8707 1.0186 0.7865 0.7936 0.8377 1.0200 0.7699 0.8530
acetyl-carnitine (acyl-C2) 11.1983 12.4563 10.6300 12.8801 12.3974 13.5490 9.0694 9.9289 10.4478 12.2906 9.1026 12.7590
Acetylcholine 0.2513 0.2052 0.1915 0.4065 0.2084 0.4134 0.2523 0.2708 0.2840 0.3959 0.3826 0.5096
acyl-C18:2 (Linoleoyl-CoA) 0.0319 0.0275 0.0270 0.0304 0.0300 0.0371 0.0160 0.0289 0.0286 0.0263 0.0258 0.0404
acyl-C20:4 0.0086 0.0075 0.0077 0.0112 0.0082 0.0140 0.0052 0.0085 0.0081 0.0080 0.0071 0.0156
acyl-C4-OH (Hydroxybutyrylcarnitine) 0.0376 0.0523 0.0287 0.0425 0.0529 0.0470 0.0245 0.0256 0.0335 0.0394 0.0267 0.0518
acyl-C5:1 (Tiglylcarnitine) 0.0220 0.0349 0.0195 0.0182 0.0242 0.0206 0.0278 0.0283 0.0120 0.0235 0.0219 0.0246
acyl-C5-OH (hydroxyisovalerylcarnitine) 0.0283 0.0206 0.0191 0.0353 0.0283 0.0268 0.0204 0.0211 0.0258 0.0244 0.0216 0.0254
Adenosine 0.0199 0.0210 0.0211 0.0263 0.0209 0.0200 0.0153 0.0174 0.0181 0.0209 0.0195 0.0146
Allantoate 0.0580 0.0495 0.0375 0.0463 0.0556 0.0367 0.0522 0.0435 0.0386 0.0445 0.0555 0.0268
Anthranilate 0.2758 0.2601 0.3521 0.2142 0.2518 0.3946 0.3238 0.2982 0.3021 0.2664 0.3681 0.3163
butanoyl-l-carnitine (acyl-C4) 0.0672 0.0612 0.0546 0.0561 0.0825 0.0715 0.0658 0.0506 0.0477 0.0435 0.0618 0.0618
Carnosine 0.0445 0.0423 0.0404 0.0428 0.0411 0.0445 0.0318 0.0413 0.0320 0.0448 0.0359 0.0478
Creatine 6.8123 9.3280 5.7713 6.8400 6.9945 5.5398 5.9165 5.9423 5.4997 7.0594 5.8955 4.7095
Creatinine 0.2331 0.2687 0.2221 0.2235 0.2326 0.1950 0.2583 0.2246 0.1854 0.2145 0.2239 0.1803
Cytidine 0.0187 0.0209 0.0154 0.0231 0.0183 0.0260 0.0116 0.0132 0.0181 0.0198 0.0105 0.0265
Cytosine 0.0251 0.0280 0.0240 0.0268 0.0299 0.0444 0.0226 0.0238 0.0242 0.0270 0.0197 0.0448
D-Glucosamine 0.0037 0.0036 0.0038 0.0050 0.0036 0.0055 0.0033 0.0046 0.0042 0.0057 0.0042 0.0053
Dimethylglycine 0.1856 0.2768 0.1207 0.2146 0.1826 0.1471 0.1862 0.1854 0.1404 0.1681 0.1757 0.1382
Dopamine 0.0566 0.0666 0.0490 0.0579 0.0590 0.0547 0.0381 0.0506 0.0359 0.0547 0.0383 0.0415
Ectoine 0.0826 0.0744 0.1009 0.0636 0.0900 0.1095 0.1179 0.0999 0.0809 0.0860 0.1053 0.1031
gamma-Glutamyl-gamma-aminobutyrate 0.0108 0.0166 0.0090 0.0105 0.0118 0.0095 0.0066 0.0094 0.0076 0.0077 0.0078 0.0064
Glutathione disulfide 1.6035 1.8026 1.7387 1.7425 1.8098 2.0774 1.3761 1.5882 1.3680 1.7123 1.4450 2.0001
g-Oxalo-crotonate 0.2795 0.1183 0.3299 0.2020 0.6088 0.6584 0.6246 0.4980 0.7908 0.5880 0.8336 0.7439
Guanidinoacetate 0.0188 0.0130 0.0133 0.0170 0.0146 0.0133 0.0126 0.0143 0.0105 0.0141 0.0168 0.0186
Guanine 0.0069 0.0087 0.0077 0.0083 0.0100 0.0077 0.0046 0.0059 0.0068 0.0081 0.0057 0.0042
Hexadecenoyl-carnitine (acyl-C16:1) 0.0128 0.0175 0.0129 0.0179 0.0152 0.0191 0.0064 0.0108 0.0126 0.0099 0.0084 0.0150
hexanoyl-L-carnitine (acyl-C6) 0.0157 0.0213 0.0101 0.0166 0.0179 0.0217 0.0080 0.0087 0.0071 0.0089 0.0079 0.0200
Hydroxyindole-acetylglycine 0.0033 0.0047 0.0039 0.0024 0.0045 0.0043 0.0069 0.0044 0.0036 0.0039 0.0041 0.0040
Hypoxanthine 1.4666 0.6951 1.7076 1.0824 2.9440 3.8493 2.5530 2.4202 4.0462 2.5926 3.3717 6.1159
IMP 0.3966 0.3778 0.5241 0.4584 0.5981 0.6278 0.2931 0.4596 0.4521 0.5141 0.3119 0.4527
Indole 0.1051 0.0867 0.1244 0.0990 0.1114 0.0763 0.1048 0.1307 0.1456 0.0936 0.1474 0.0843
Indolepyruvate 0.0282 0.0156 0.0152 0.0133 0.0312 0.0325 0.0248 0.0372 0.0233 0.0329 0.0209 0.0284
Indoxyl 0.1840 0.1325 0.1451 0.1376 0.1873 0.1649 0.2438 0.2351 0.1466 0.1525 0.2304 0.0599
Inosine 0.0319 0.0114 0.0340 0.0216 0.0681 0.1068 0.0474 0.0635 0.0743 0.0489 0.0790 0.2290
kynurenine 0.0232 0.0278 0.0140 0.0214 0.0246 0.0202 0.0373 0.0436 0.0207 0.0321 0.0300 0.0223
L-Adrenaline 0.0451 0.0597 0.0394 0.0426 0.0432 0.0372 0.0284 0.0383 0.0331 0.0438 0.0260 0.0270
L-alanine 2.5132 2.3503 2.7327 2.1457 2.0995 2.1691 2.7591 2.7804 2.0648 2.4657 2.5877 1.7045
L-arginine 0.3059 0.4262 0.4149 0.3061 0.3472 0.4094 0.4419 0.5088 0.4437 0.5222 0.4500 0.5074
L-asparagine 0.0684 0.1040 0.0540 0.0707 0.1026 0.0641 0.0869 0.0733 0.0641 0.0608 0.0700 0.0976
L-aspartate 0.0178 0.0195 0.0113 0.0129 0.0111 0.0169 0.0240 0.0165 0.0109 0.0159 0.0145 0.0173
L-Carnitine 2.7358 2.2546 2.1504 2.4590 2.0108 2.1360 1.7195 2.0121 1.7231 2.1367 1.6195 1.8572
L-Citrulline 0.2261 0.1372 0.1704 0.1740 0.1705 0.1693 0.2081 0.1707 0.1570 0.1768 0.1860 0.1680
L-cystine 0.0048 0.0079 0.0064 0.0053 0.0055 0.0039 0.0065 0.0059 0.0045 0.0049 0.0047 0.0031
L-glutamate 0.2649 0.2624 0.2741 0.2626 0.2694 0.3735 0.2219 0.2251 0.2402 0.2821 0.2128 0.3503
L-glutamine 1.2227 1.2618 1.2515 1.2641 1.0717 1.1276 0.9946 1.0394 0.9734 1.3161 1.0228 0.9335
L-histidine 0.3520 0.2807 0.3456 0.3432 0.3066 0.2732 0.3592 0.3809 0.3508 0.4247 0.3856 0.3249
L-Homocysteine 0.0116 0.0204 0.0038 0.0147 0.0105 0.0058 0.0061 0.0127 0.0093 0.0129 0.0106 0.0052
L-leucine/isoleucine 14.3222 16.7184 15.4372 15.9092 14.7171 15.0179 15.3408 13.4722 14.5688 13.6908 13.5900 14.9266
L-lysine 1.4528 1.8584 1.6851 1.5676 1.5457 1.5593 1.6371 1.8106 1.5163 2.0057 1.8554 1.8744
L-methionine 2.5295 2.0393 2.9006 2.2830 2.2283 2.7902 3.7322 2.7992 2.5317 2.4162 3.1628 3.1824
L-Methionine S-oxide 0.0641 0.0663 0.0641 0.0751 0.0673 0.0649 0.0767 0.0665 0.0619 0.0651 0.0693 0.0500
L-octanoylcarnitine (acyl-C8) 0.0113 0.0133 0.0088 0.0114 0.0119 0.0441 0.0051 0.0061 0.0066 0.0097 0.0050 0.0367
L-Palmitoylcarnitine (acyl-C16) 0.1016 0.1108 0.1008 0.1195 0.1107 0.1243 0.0563 0.0912 0.0871 0.1015 0.0809 0.1182
L-phenylalanine 2.5919 2.4535 2.3372 2.5874 2.3580 2.1716 2.1775 2.0766 2.0461 2.2124 1.9316 1.9631
L-proline 6.4595 5.4108 5.9420 4.8614 5.2113 5.2317 7.0613 6.9631 5.5671 5.7668 6.5492 5.4780
L-serine 0.0880 0.0768 0.0899 0.0873 0.0758 0.0863 0.0982 0.1088 0.0891 0.1169 0.1147 0.0904
L-threonine 0.2747 0.3650 0.3255 0.2987 0.2803 0.3121 0.4758 0.4293 0.3943 0.3773 0.5006 0.3862
L-tryptophan 11.0191 9.0880 13.1325 10.5017 11.7990 8.4013 12.1124 13.9719 14.3267 10.9777 14.7991 8.7318
L-tyrosine 2.3422 1.2480 1.7046 2.2293 1.8266 1.4519 2.3538 1.9132 1.9716 2.0840 1.8923 2.0345
L-valine 16.1487 14.8048 14.8035 15.4735 14.9823 14.3968 16.9665 16.2795 15.5216 15.2075 16.2441 14.4832
N-Acetylornithine 0.2749 0.2531 0.2624 0.2656 0.2769 0.3544 0.2031 0.1930 0.1693 0.2049 0.1559 0.2099
NAD+ 0.0393 0.0331 0.0303 0.0369 0.0407 0.0373 0.0261 0.0269 0.0195 0.0296 0.0262 0.0267
NADP+ 0.0158 0.0155 0.0133 0.0161 0.0145 0.0143 0.0133 0.0140 0.0111 0.0160 0.0132 0.0114
N-formyl kynurenine 0.0445 0.0597 0.0364 0.0451 0.0442 0.0360 0.0311 0.0629 0.0221 0.0553 0.0302 0.0334
Nicotinamide 2.8606 3.3953 3.0495 3.4498 2.8827 3.7984 2.4637 2.7079 2.5577 3.3186 2.3666 3.3375
N-Methylethanolamine phosphate 0.0454 0.0250 0.0248 0.0261 0.0274 0.0241 0.0547 0.0457 0.0358 0.0422 0.0500 0.0257
octenoyl-l-carnitine (acyl-C8:1) 0.0030 0.0030 0.0018 0.0035 0.0030 0.0070 0.0019 0.0028 0.0018 0.0021 0.0013 0.0073
O-Decenoyl-L-carnitine (acyl-C10:1) 0.0091 0.0092 0.0051 0.0076 0.0066 0.0263 0.0037 0.0048 0.0043 0.0066 0.0044 0.0252
O-dodecanoyl-carnitine (acyl-C12) 0.0128 0.0088 0.0056 0.0081 0.0095 0.0103 0.0036 0.0063 0.0058 0.0067 0.0045 0.0094
O-dodecenoyl-carnitine (acyl-C12:1) 0.0053 0.0052 0.0026 0.0040 0.0039 0.0040 0.0024 0.0026 0.0021 0.0025 0.0021 0.0034
O-octadecenoyl-L-carnitine (acyl-C18:1) 0.0500 0.0630 0.0457 0.0526 0.0532 0.0466 0.0226 0.0415 0.0336 0.0402 0.0317 0.0433
Ornithine 0.2433 0.2208 0.1820 0.2184 0.2419 0.1836 0.1960 0.1972 0.1825 0.1761 0.2595 0.1638
O-tetradecanoyl-L-carnitine (acyl-C14) 0.0225 0.0182 0.0170 0.0214 0.0206 0.0223 0.0095 0.0149 0.0152 0.0135 0.0124 0.0263
Pantetheine 0.0055 0.0066 0.0062 0.0053 0.0059 0.0038 0.0058 0.0073 0.0060 0.0060 0.0063 0.0036
Pantetheine 4--phosphate 0.0046 0.0053 0.0048 0.0049 0.0043 0.0066 0.0038 0.0055 0.0044 0.0059 0.0057 0.0064
Pantothenol 0.0784 0.1121 0.0710 0.0936 0.1226 0.1065 0.0584 0.0638 0.0602 0.0696 0.0551 0.0786
Phosphate 2.5947 2.9244 2.4293 2.6888 2.5850 1.5446 1.7928 2.0309 2.1417 2.1105 1.9979 1.1303
propionyl-carnitine (acyl-C3) 0.1605 0.1296 0.1019 0.1116 0.1653 0.2042 0.1273 0.1099 0.1240 0.1141 0.1116 0.2389
Putrescine 0.0027 0.0026 0.0031 0.0030 0.0030 0.0054 0.0013 0.0012 0.0019 0.0022 0.0014 0.0055
Pyridoxamine 5^-phosphate 0.0398 0.0347 0.0334 0.0435 0.0493 0.0274 0.0559 0.0423 0.0459 0.0517 0.0463 0.0233
S-Adenosyl-L-methionine 0.0045 0.0050 0.0053 0.0047 0.0041 0.0058 0.0047 0.0048 0.0046 0.0055 0.0048 0.0065
S-Glutathionyl-L-cysteine 0.0722 0.0842 0.0729 0.0740 0.0729 0.0704 0.0759 0.0753 0.0681 0.0784 0.0738 0.0572
Spermidine 0.2045 0.1524 0.1909 0.2211 0.1703 1.8330 0.1433 0.1411 0.1385 0.2201 0.1327 1.9680
Spermine 0.0223 0.0201 0.0192 0.0282 0.0172 0.0929 0.0221 0.0309 0.0182 0.0332 0.0188 0.1017
Sphingosine 0.2470 0.2166 0.2489 0.2719 0.2030 0.2174 0.1270 0.2528 0.1678 0.1846 0.1961 0.1379
Taurine 0.3824 0.4196 0.4331 0.3677 0.4622 0.5405 0.2539 0.2536 0.3425 0.3840 0.2809 0.4012
Tetradecenoyl Carnitine (acyl-C14:1) 0.0102 0.0133 0.0073 0.0103 0.0117 0.0085 0.0046 0.0076 0.0055 0.0062 0.0053 0.0087
trans-4-Hydroxy-L-proline 0.0811 0.0699 0.0779 0.0688 0.0742 0.0761 0.0978 0.1018 0.0807 0.0849 0.0897 0.0803
Xanthine 0.1846 0.1025 0.2154 0.1334 0.3203 0.4216 0.2109 0.2007 0.2804 0.2402 0.2895 0.3569
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Factors:

F1Treatment:IV iron | Radiation Dose:Gy10
F2Treatment:IV iron | Radiation Dose:Gy11
F3Treatment:IV iron | Radiation Dose:Gy7
F4Treatment:IV iron | Radiation Dose:Gy8
F5Treatment:IV iron | Radiation Dose:Gy9
F6Treatment:IV iron | Radiation Dose:no irradiated
F7Treatment:Saline | Radiation Dose:Gy10
F8Treatment:Saline | Radiation Dose:Gy11
F9Treatment:Saline | Radiation Dose:Gy7
F10Treatment:Saline | Radiation Dose:Gy8
F11Treatment:Saline | Radiation Dose:Gy9
F12Treatment:Saline | Radiation Dose:no irradiated
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