RefMet Compound Details

RefMet ID, RefMet name, exact mass and formula
RefMet IDRM0153554
RefMet name2-Hydroxyglutaric acid
Systematic name(2S)-2-hydroxypentanedioic acid
SynonymsPubChem Synonyms
Sum CompositionFA 5:1;O3 View other entries in RefMet with this sum composition
Exact mass148.037175 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC5H8O5View other entries in RefMet with this formula
Molecular descriptors
Molfile77475 (Download molfile/View MW Metabolite Database details)
InChIInChI=1S/C5H8O5/c6-3(5(9)10)1-2-4(7)8/h3,6H,1-2H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKeyHWXBTNAVRSUOJR-UHFFFAOYSA-NView other enantiomers/diastereomers of this metabolite in RefMet
SMILESC(CC(=O)O)C(C(=O)O)O
Run Tanimoto similarity search (with similarity coefficient >=0.6)
Chemical/Biochemical Classification
Super ClassFatty Acyls
Main ClassFatty acids
Sub ClassDicarboxylic acids
Distribution of 2-Hydroxyglutaric acid in NMDR studies
SpeciesPlot Species distribution
Sample sourcePlot Sample source(tissue) distribution
PlatformPlatform (MS/NMR) used for detection
ChromatographyChromatography methods used for detection
StudiesNMDR Studies reporting 2-Hydroxyglutaric acid
External Links
Pubchem CID43
LIPID MAPSLMFA01050483
ChEBI ID17084
KEGG IDC02630
HMDB IDHMDB0059655
Structural annotation level
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving 2-Hydroxyglutaric acid

Rxn IDKEGG ReactionEnzyme
R03534 2-Hydroxyglutarate + FAD <=> 2-Oxoglutarate + FADH22-Hydroxyglutarate:(acceptor) 2-oxidoreductase

Table of KEGG human pathways containing 2-Hydroxyglutaric acid

Pathway IDHuman Pathway# of reactions
hsa00650 Butanoate metabolism 1
  logo